Which bus from Mesa, AZ to St. Louis, MO is the cheapest?

Compare all bus companies and find the best price: Bus tickets from $107
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Compare all timetables for the bus from Mesa, AZ to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Mesa, AZ to St. Louis, MO from various bus operators like Greyhound US for the next days.

today
$122
tomorrow
$130
Saturday
Sunday
$127
Monday
Tuesday
$168
Wednesday

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 33h 15m 7:55 PM Mesa, AZ Greyhound 7:10 AM St. Louis, MO Gateway Station  Economy $122

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 37h 5m 7:40 AM Mesa, AZ Greyhound 10:45 PM St. Louis, MO Gateway Station  Economy $130
Greyhound US 33h 15m 7:55 PM Mesa, AZ Greyhound 7:10 AM St. Louis, MO Gateway Station  Economy $141

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 37h 5m 7:40 AM Mesa, AZ Greyhound 10:45 PM St. Louis, MO Gateway Station  Economy $127
Greyhound US 33h 15m 7:55 PM Mesa, AZ Greyhound 7:10 AM St. Louis, MO Gateway Station  Economy $150

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 37h 5m 7:40 AM Mesa, AZ Greyhound 10:45 PM St. Louis, MO Gateway Station  Economy $168
Greyhound US 33h 15m 7:55 PM Mesa, AZ Greyhound 7:10 AM St. Louis, MO Gateway Station  Economy $174
  • Did you know that if you travel from Mesa, AZ to St. Louis, MO via Phoenix, AZ, you can save more than $42? You can find the corresponding connections below.
    • Greyhound US
      48h 50m
      0
      7:55 PM
      Mesa, AZ
      Greyhound
      8:15 PM
      Phoenix, AZ
      Bus Station
      0
      Greyhound US
      Economy
      $3
      • Waiting Time 13h 20m
    • Greyhound US
      35h 10m
      0
      9:35 AM
      Phoenix, AZ
      Bus Station
      10:45 PM
      St. Louis, MO
      Gateway Station
      0
      Greyhound US
      Economy
      $123
    Travel time is 13h 35m longer, but you will save $42

Best Price Offer: The price for the cheapest bus from Mesa, AZ to St. Louis, MO is $107 on 8/24/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Mesa, AZ and St. Louis, MO

See here how frequent the connections between Mesa, AZ and St. Louis, MO are, during different times and days of the week.
Tuesday is the busiest day, with more than 4 daily buses from Mesa, AZ to St. Louis, MO. Thursday has instead the fewest connections, with only 1 daily coaches between Mesa, AZ and St. Louis, MO.
The busiest time of the day is the Evening, with 6 buses from Mesa, AZ to St. Louis, MO, while Morning sees the fewest connections between Mesa, AZ and St. Louis, MO, with 5 offers.

Facts about the bus from Mesa, AZ to St. Louis, MO

Compare all providers like Greyhound US that travel 2 times every day by bus from Mesa, AZ to St. Louis, MO in one click! Book your bus ticket from Mesa, AZ to St. Louis, MO starting from $107!

Cheapest Bus $107
Fastest Bus 35h 15m
Earliest Bus 7:55 PM
Latest Bus 7:55 PM
Daily Bus Routes 2 Ø
Distance 1,258.1 miles
Bus Companies Greyhound US

Cheapest bus connections from Mesa, AZ to St. Louis, MO

Every day, 2 buses from 1 bus companies leave Mesa, AZ for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 08/27/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 08/23
Monday 08/24
Tuesday 08/25
Wednesday 08/26
Thursday 08/27
$118
Friday 08/28
$134
Saturday 08/29
Sunday 08/30
$127
Monday 08/31
Tuesday 09/01
$172
Wednesday 09/02
Thursday 09/03
$141
Friday 09/04
Saturday 09/05
Sunday 09/06
$145
Monday 09/07
$120
Tuesday 09/08
Wednesday 09/09
$124
Thursday 09/10
$124
Friday 09/11
$123
Saturday 09/12
Sunday 09/13
$120
Monday 09/14
$118
Tuesday 09/15
$122
Wednesday 09/16
Thursday 09/17
$133
Friday 09/18
$125
Saturday 09/19

The cheapest time to travel from Mesa, AZ to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Mesa, AZ to St. Louis, MO, for the next 30 days.
With a price starting from $118, Thursday is the cheapest day for a bus from Mesa, AZ to St. Louis, MO. Friday instead is the most expensive day with prices starting from $123.
Evening is the cheapest day time for bus tickets from Mesa, AZ to St. Louis, MO, with $122. Morning is the most expensive time of the day with prices starting from $127.

How to save money travelling from Mesa, AZ to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mesa, AZ to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mesa, AZ to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mesa, AZ to St. Louis, MO are also emptier.

All bus stations and stops in Mesa, AZ and St. Louis, MO

In the map below, you can see where to find all bus stations in Mesa, AZ and St. Louis, MO.

Service and Comfort on the bus from Mesa, AZ to St. Louis, MO

Want to know which seat classes are available on the buses from Mesa, AZ to St. Louis, MO? Or which bus companies serve the route Mesa, AZ to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Mesa, AZ to St. Louis, MO bus

How much does a Mesa, AZ St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $107 and takes 35h 15m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Mesa, AZ to St. Louis, MO?

This route is offered by 1 companies with a range of ticket prices between $107 and $178. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Mesa, AZ to St. Louis, MO each day?

Every day, the Mesa, AZ to St. Louis, MO bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mesa, AZ to St. Louis, MO take?

The fastest bus from Mesa, AZ to St. Louis, MO is offered by Greyhound US and takes 35h 15m. Bus tickets for this connection cost $122. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mesa, AZ to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Mesa, AZ starts at 7:55 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mesa, AZ to St. Louis, MO?

The latest bus trip departing from Mesa, AZ for St. Louis, MO starts at 7:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mesa, AZ St. Louis, MO route?

When traveling by bus from Mesa, AZ to St. Louis, MO, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mesa, AZ and St. Louis, MO?

You can check all the direct connections between Mesa, AZ and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Mesa, AZ to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mesa, AZ St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mesa, AZ St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mesa, AZ to St. Louis, MO on your planned travel date.

How does CheckMyBus find the best bus deals from Mesa, AZ to St. Louis, MO?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Mesa, AZ and St. Louis, MO. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Mesa, AZ to St. Louis, MO?

Prices and availability for 2 trips between Mesa, AZ and St. Louis, MO change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Mesa, AZ to St. Louis, MO

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mesa, AZ and to St. Louis, MO

Here’s an overview of the most popular bus routes to Mesa, AZ and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!
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From Champaign, IL to St. Louis, MO bus From Champaign, IL to St. Louis, MO bus
Buses Clarksville, TN - St. Louis, MO Buses Clarksville, TN - St. Louis, MO
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Popular Airport Shuttles to Mesa, AZ and to St. Louis, MO
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