Which bus from Philadelphia to St. Louis, MO is the cheapest?

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Compare all timetables for the bus from Philadelphia to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Philadelphia to St. Louis, MO from various bus operators like Greyhound US or FlixBus for the next days.

today
$81
tomorrow
$88
Monday
$80
Tuesday
$81
Wednesday
$79
Thursday
Friday

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 22h 35m 5:35 PM Philadelphia Central Bus Station 3:10 PM St. Louis, MO Gateway Station  Economy $81
Greyhound US 20h 50m 12:05 PM Philadelphia Central Bus Station 7:55 AM St. Louis, MO Gateway Station  Economy $86
Greyhound US 20h 50m 3:25 AM Philadelphia Central Bus Station 11:15 PM St. Louis, MO Gateway Station  Economy $94
FlixBus 24h 20m 11:55 PM Philadelphia Central Bus Station 11:15 PM St. Louis, MO Gateway Station  Economy $108

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 22h 35m 5:35 PM Philadelphia Central Bus Station 3:10 PM St. Louis, MO Gateway Station  Economy $88
Greyhound US 20h 50m 3:25 AM Philadelphia Central Bus Station 11:15 PM St. Louis, MO Gateway Station  Economy $93
Greyhound US 20h 50m 12:05 PM Philadelphia Central Bus Station 7:55 AM St. Louis, MO Gateway Station  Economy $97
FlixBus 24h 20m 11:55 PM Philadelphia Central Bus Station 11:15 PM St. Louis, MO Gateway Station  Economy $112

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 22h 35m 5:35 PM Philadelphia Central Bus Station 3:10 PM St. Louis, MO Gateway Station  Economy $80
Greyhound US 20h 50m 12:05 PM Philadelphia Central Bus Station 7:55 AM St. Louis, MO Gateway Station  Economy $82
FlixBus 24h 20m 11:55 PM Philadelphia Central Bus Station 11:15 PM St. Louis, MO Gateway Station  Economy $100
Greyhound US 20h 50m 3:25 AM Philadelphia Central Bus Station 11:15 PM St. Louis, MO Gateway Station  Economy $104

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 20h 50m 12:05 PM Philadelphia Central Bus Station 7:55 AM St. Louis, MO Gateway Station  Economy $81
Greyhound US 20h 50m 3:25 AM Philadelphia Central Bus Station 11:15 PM St. Louis, MO Gateway Station  Economy $91
FlixBus 24h 20m 11:55 PM Philadelphia Central Bus Station 11:15 PM St. Louis, MO Gateway Station  Economy $97
Greyhound US 22h 35m 5:35 PM Philadelphia Central Bus Station 3:10 PM St. Louis, MO Gateway Station  Economy $202

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 22h 35m 5:35 PM Philadelphia Central Bus Station 3:10 PM St. Louis, MO Gateway Station  Economy $79
Greyhound US 20h 50m 12:05 PM Philadelphia Central Bus Station 7:55 AM St. Louis, MO Gateway Station  Economy $83
Greyhound US 20h 50m 3:25 AM Philadelphia Central Bus Station 11:15 PM St. Louis, MO Gateway Station  Economy $97
Greyhound US 28h 55m 7:20 PM Philadelphia Central Bus Station 11:15 PM St. Louis, MO Gateway Station  Economy $104

Best Price Offer: The price for the cheapest bus from Philadelphia to St. Louis, MO is $79 on 10/28/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Philadelphia and St. Louis, MO

See here how frequent the connections between Philadelphia and St. Louis, MO are, during different times and days of the week.
Sunday is the busiest day, with more than 8 daily buses from Philadelphia to St. Louis, MO. Wednesday has instead the fewest connections, with only 4 daily coaches between Philadelphia and St. Louis, MO.
The busiest time of the day is the Afternoon, with 18 buses from Philadelphia to St. Louis, MO, while Evening sees the fewest connections between Philadelphia and St. Louis, MO, with 9 offers.

Facts about the bus from Philadelphia to St. Louis, MO

Compare all providers like Greyhound US and FlixBus that travel 7 times every day by bus from Philadelphia to St. Louis, MO in one click! Book your bus ticket from Philadelphia to St. Louis, MO starting from $79!

Cheapest Bus $79
Fastest Bus 19h 50m
Earliest Bus 3:25 AM
Latest Bus 7:20 PM
Daily Bus Routes 7 Ø
Distance 807.9 miles
Bus Companies Greyhound US and FlixBus

Cheapest bus connections from Philadelphia to St. Louis, MO

Every day, 7 buses from 2 bus companies leave Philadelphia for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/24/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 10/18
Monday 10/19
Tuesday 10/20
Wednesday 10/21
Thursday 10/22
Friday 10/23
Saturday 10/24
$81
Sunday 10/25
$88
Monday 10/26
$80
Tuesday 10/27
$81
Wednesday 10/28
$79
Thursday 10/29
Friday 10/30
Saturday 10/31
$91
Sunday 11/01
Monday 11/02
$93
Tuesday 11/03
$88
Wednesday 11/04
$83
Thursday 11/05
Friday 11/06
$86
Saturday 11/07
$93
Sunday 11/08
$89
Monday 11/09
$85
Tuesday 11/10
$94
Wednesday 11/11
$86
Thursday 11/12
$83
Friday 11/13
Saturday 11/14

The cheapest time to travel from Philadelphia to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Philadelphia to St. Louis, MO, for the next 30 days.
With a price starting from $79, Tuesday is the cheapest day for a bus from Philadelphia to St. Louis, MO. Sunday instead is the most expensive day with prices starting from $88.
Afternoon is the cheapest day time for bus tickets from Philadelphia to St. Louis, MO, with $79. Evening is the most expensive time of the day with prices starting from $97.

How to save money travelling from Philadelphia to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Philadelphia to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Philadelphia to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Philadelphia to St. Louis, MO are also emptier.

Beloved bus companies from Philadelphia to St. Louis, MO

These are the most booked bus companies between Philadelphia to St. Louis, MO from our users.

Greyhound US from Philadelphia to St. Louis, MO

Greyhound US

Here you will find the key facts about the Greyhound US bus route Philadelphia to St. Louis, MO:

Cheapest Price $79
Fastest Bus 19h 50m
Earliest Bus 3:25 AM
Last Bus 7:20 PM
Daily Connections 5 Ø
Found on 10/13/2026

All bus stations and stops in Philadelphia and St. Louis, MO

In the map below, you can see where to find all bus stations in Philadelphia and St. Louis, MO.

Service and Comfort on the bus from Philadelphia to St. Louis, MO

Want to know which seat classes are available on the buses from Philadelphia to St. Louis, MO? Or which bus companies serve the route Philadelphia to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Philadelphia to St. Louis, MO bus

How much does a Philadelphia St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $79 and takes 21h 35m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Philadelphia to St. Louis, MO?

This route is offered by 2 companies with a range of ticket prices between $79 and $206. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Philadelphia to St. Louis, MO each day?

Every day, the Philadelphia to St. Louis, MO bus route is served by approximately 7 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Philadelphia to St. Louis, MO take?

The fastest bus from Philadelphia to St. Louis, MO is offered by Greyhound US and takes 19h 50m. Bus tickets for this connection cost $98. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Philadelphia to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Philadelphia starts at 3:25 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Philadelphia to St. Louis, MO?

The latest bus trip departing from Philadelphia for St. Louis, MO starts at 7:20 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Philadelphia St. Louis, MO route?

When traveling by bus from Philadelphia to St. Louis, MO, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Philadelphia and St. Louis, MO?

You can check all the direct connections between Philadelphia and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Philadelphia to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Philadelphia St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Philadelphia St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Philadelphia to St. Louis, MO on your planned travel date.

How does CheckMyBus find the best bus deals from Philadelphia to St. Louis, MO?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 7 daily trips between Philadelphia and St. Louis, MO. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Philadelphia to St. Louis, MO?

Prices and availability for 7 trips between Philadelphia and St. Louis, MO change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Philadelphia to St. Louis, MO

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Philadelphia and to St. Louis, MO

Here’s an overview of the most popular bus routes to Philadelphia and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Philadelphia and to St. Louis, MO
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