Which bus from Lafayette, LA to St. Louis, MO is the cheapest?

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Compare all timetables for the bus from Lafayette, LA to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Lafayette, LA to St. Louis, MO from various bus operators like Greyhound US or FlixBus for the next days.

today
tomorrow
$111
Sunday
$108
Monday
Tuesday
$108
Wednesday
$108
Thursday
$104

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 16h 45m 9:30 PM Lafayette, LA TA Travel Center 2:15 PM St. Louis, MO Gateway Station  Economy $111
Greyhound US 19h 10m 3:50 AM Lafayette, LA Bus Stop 11:00 PM St. Louis, MO Gateway Station  Economy $111
Greyhound US 20h 50m 5:25 PM Lafayette, LA Bus Stop 2:15 PM St. Louis, MO Gateway Station  Economy $111
Greyhound US 24h 35m 10:10 PM Lafayette, LA Bus Stop 10:45 PM St. Louis, MO Gateway Station  Economy $111
FlixBus 30h 55m 2:25 AM Lafayette, LA TA Travel Center 9:20 AM St. Louis, MO Gateway Station  Economy $112
  • Did you know that if you travel from Lafayette, LA to St. Louis, MO via New Orleans, LA, you can save more than $28? You can find the corresponding connections below.
    • FlixBus
      20h 35m
      0
      2:25 AM
      Lafayette, LA
      TA Travel Center
      4:55 AM
      New Orleans, LA
      Central Bus Station
      0
      FlixBus
      Economy
      $19
      • Waiting Time 3h 25m
    • Greyhound US
      14h 40m
      0
      8:20 AM
      New Orleans, LA
      Central Bus Station
      11:00 PM
      St. Louis, MO
      Gateway Station
      0
      Greyhound US
      Economy
      $64
    Travel time is 3h 50m longer, but you will save $28

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 25h 20m 9:25 PM Lafayette, LA Bus Stop 10:45 PM St. Louis, MO Gateway Station  Economy $108
FlixBus 16h 45m 9:30 PM Lafayette, LA TA Travel Center 2:15 PM St. Louis, MO Gateway Station  Economy $109
Greyhound US 20h 50m 5:25 PM Lafayette, LA Bus Stop 2:15 PM St. Louis, MO Gateway Station  Economy $109
FlixBus 30h 55m 2:25 AM Lafayette, LA TA Travel Center 9:20 AM St. Louis, MO Gateway Station  Economy $110
Greyhound US 23h 45m 9:35 AM Lafayette, LA Bus Stop 9:20 AM St. Louis, MO Gateway Station  Economy $112
  • Did you know that if you travel from Lafayette, LA to St. Louis, MO via New Orleans, LA, you can save more than $29? You can find the corresponding connections below.
    • FlixBus
      20h 35m
      0
      2:25 AM
      Lafayette, LA
      TA Travel Center
      4:55 AM
      New Orleans, LA
      Central Bus Station
      0
      FlixBus
      Economy
      $19
      • Waiting Time 3h 25m
    • Greyhound US
      14h 40m
      0
      8:20 AM
      New Orleans, LA
      Canal and Charles
      11:00 PM
      St. Louis, MO
      Gateway Station
      0
      Greyhound US
      Economy
      $60
    Travel time is 3h 50m longer, but you will save $29

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 25h 20m 9:25 PM Lafayette, LA Bus Stop 10:45 PM St. Louis, MO Gateway Station  Economy $108
Greyhound US 27h 35m 9:20 AM Lafayette, LA Bus Stop 12:55 PM St. Louis, MO Gateway Station  Economy $114
Greyhound US 28h 5m 5:25 PM Lafayette, LA Bus Stop 9:30 PM St. Louis, MO Gateway Station  Economy $114
FlixBus 28h 35m 8:20 AM Lafayette, LA TA Travel Center 12:55 PM St. Louis, MO Gateway Station  Economy $115
FlixBus 32h 40m 12:50 PM Lafayette, LA TA Travel Center 9:30 PM St. Louis, MO Gateway Station  Economy $115
  • Did you know that if you travel from Lafayette, LA to St. Louis, MO via New Orleans, LA, you can save more than $29? You can find the corresponding connections below.
    • FlixBus
      20h 35m
      0
      2:25 AM
      Lafayette, LA
      TA Travel Center
      4:55 AM
      New Orleans, LA
      Central Bus Station
      0
      FlixBus
      Economy
      $19
      • Waiting Time 3h 25m
    • Greyhound US
      14h 40m
      0
      8:20 AM
      New Orleans, LA
      Canal and Charles
      11:00 PM
      St. Louis, MO
      Gateway Station
      0
      Greyhound US
      Economy
      $60
    Travel Time is 4h 45m shorter, and you will save $29

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 23h 45m 9:35 AM Lafayette, LA Bus Stop 9:20 AM St. Louis, MO Gateway Station  Economy $108
Greyhound US 25h 20m 9:25 PM Lafayette, LA Bus Stop 10:45 PM St. Louis, MO Gateway Station  Economy $108
Greyhound US 28h 5m 5:25 PM Lafayette, LA Bus Stop 9:30 PM St. Louis, MO Gateway Station  Economy $111
FlixBus 32h 40m 12:50 PM Lafayette, LA TA Travel Center 9:30 PM St. Louis, MO Gateway Station  Economy $111
  • Did you know that if you travel from Lafayette, LA to St. Louis, MO via New Orleans, LA, you can save more than $29? You can find the corresponding connections below.
    • FlixBus
      20h 35m
      0
      2:25 AM
      Lafayette, LA
      TA Travel Center
      4:55 AM
      New Orleans, LA
      Central Bus Station
      0
      FlixBus
      Economy
      $19
      • Waiting Time 3h 25m
    • Greyhound US
      14h 40m
      0
      8:20 AM
      New Orleans, LA
      Canal and Charles
      11:00 PM
      St. Louis, MO
      Gateway Station
      0
      Greyhound US
      Economy
      $60
    Travel Time is 3h 10m shorter, and you will save $29

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 23h 45m 9:35 AM Lafayette, LA Bus Stop 9:20 AM St. Louis, MO Gateway Station  Economy $104
FlixBus 16h 45m 9:30 PM Lafayette, LA TA Travel Center 2:15 PM St. Louis, MO Gateway Station  Economy $105
Greyhound US 27h 50m 3:15 AM Lafayette, LA Bus Stop 7:05 AM St. Louis, MO Gateway Station  Economy $105
Greyhound US 20h 50m 5:25 PM Lafayette, LA Bus Stop 2:15 PM St. Louis, MO Gateway Station  Economy $105
FlixBus 30h 55m 2:25 AM Lafayette, LA TA Travel Center 9:20 AM St. Louis, MO Gateway Station  Economy $106
  • Did you know that if you travel from Lafayette, LA to St. Louis, MO via New Orleans, LA, you can save more than $25? You can find the corresponding connections below.
    • FlixBus
      20h 35m
      0
      2:25 AM
      Lafayette, LA
      TA Travel Center
      4:55 AM
      New Orleans, LA
      Central Bus Station
      0
      FlixBus
      Economy
      $19
      • Waiting Time 3h 25m
    • Greyhound US
      14h 40m
      0
      8:20 AM
      New Orleans, LA
      Canal and Charles
      11:00 PM
      St. Louis, MO
      Gateway Station
      0
      Greyhound US
      Economy
      $60
    Travel time is 3h 50m longer, but you will save $25

Best Price Offer: The price for the cheapest bus from Lafayette, LA to St. Louis, MO is $92 on 11/7/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Lafayette, LA and St. Louis, MO

See here how frequent the connections between Lafayette, LA and St. Louis, MO are, during different times and days of the week.
Sunday is the busiest day, with more than 8 daily buses from Lafayette, LA to St. Louis, MO. Wednesday has instead the fewest connections, with only 4 daily coaches between Lafayette, LA and St. Louis, MO.
The busiest time of the day is the Morning, with 8 buses from Lafayette, LA to St. Louis, MO, while Afternoon sees the fewest connections between Lafayette, LA and St. Louis, MO, with 7 offers.

Facts about the bus from Lafayette, LA to St. Louis, MO

Compare all providers like Greyhound US and FlixBus that travel 6 times every day by bus from Lafayette, LA to St. Louis, MO in one click! Book your bus ticket from Lafayette, LA to St. Louis, MO starting from $92!

Cheapest Bus $92
Fastest Bus 16h 45m
Earliest Bus 1:30 AM
Latest Bus 9:30 PM
Daily Bus Routes 6 Ø
Distance 589.7 miles
Bus Companies Greyhound US and FlixBus

Cheapest bus connections from Lafayette, LA to St. Louis, MO

Every day, 6 buses from 2 bus companies leave Lafayette, LA for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/23/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 10/18
Monday 10/19
Tuesday 10/20
Wednesday 10/21
Thursday 10/22
Friday 10/23
Saturday 10/24
$111
Sunday 10/25
$108
Monday 10/26
Tuesday 10/27
$108
Wednesday 10/28
$108
Thursday 10/29
$104
Friday 10/30
Saturday 10/31
$119
Sunday 11/01
Monday 11/02
$109
Tuesday 11/03
Wednesday 11/04
$108
Thursday 11/05
Friday 11/06
$93
Saturday 11/07
$92
Sunday 11/08
$96
Monday 11/09
$99
Tuesday 11/10
$109
Wednesday 11/11
$102
Thursday 11/12
$108
Friday 11/13
Saturday 11/14

The cheapest time to travel from Lafayette, LA to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Lafayette, LA to St. Louis, MO, for the next 30 days.
With a price starting from $92, Saturday is the cheapest day for a bus from Lafayette, LA to St. Louis, MO. Tuesday instead is the most expensive day with prices starting from $108.
Night is the cheapest day time for bus tickets from Lafayette, LA to St. Louis, MO, with $92. Afternoon is the most expensive time of the day with prices starting from $105.

How to save money travelling from Lafayette, LA to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Lafayette, LA to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Lafayette, LA to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Lafayette, LA to St. Louis, MO are also emptier.

Beloved bus companies from Lafayette, LA to St. Louis, MO

These are the most booked bus companies between Lafayette, LA to St. Louis, MO from our users.

Greyhound US from Lafayette, LA to St. Louis, MO

Greyhound US

Here you will find the key facts about the Greyhound US bus route Lafayette, LA to St. Louis, MO:

Cheapest Price $104
Fastest Bus 19h 10m
Earliest Bus 3:50 AM
Last Bus 9:25 PM
Daily Connections 3 Ø
Found on 9/29/2026

All bus stations and stops in Lafayette, LA and St. Louis, MO

In the map below, you can see where to find all bus stations in Lafayette, LA and St. Louis, MO.

Service and Comfort on the bus from Lafayette, LA to St. Louis, MO

Want to know which seat classes are available on the buses from Lafayette, LA to St. Louis, MO? Or which bus companies serve the route Lafayette, LA to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Lafayette, LA to St. Louis, MO bus

How much does a Lafayette, LA St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $92 and takes 23h 45m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Lafayette, LA to St. Louis, MO?

This route is offered by 2 companies with a range of ticket prices between $92 and $127. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Lafayette, LA to St. Louis, MO each day?

Every day, the Lafayette, LA to St. Louis, MO bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Lafayette, LA to St. Louis, MO take?

The fastest bus from Lafayette, LA to St. Louis, MO is offered by FlixBus and takes 16h 45m. Bus tickets for this connection cost $111. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Lafayette, LA to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Lafayette, LA starts at 1:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Lafayette, LA to St. Louis, MO?

The latest bus trip departing from Lafayette, LA for St. Louis, MO starts at 9:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Lafayette, LA St. Louis, MO route?

When traveling by bus from Lafayette, LA to St. Louis, MO, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Lafayette, LA and St. Louis, MO?

You can check all the direct connections between Lafayette, LA and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Lafayette, LA to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Lafayette, LA St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Lafayette, LA St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Lafayette, LA to St. Louis, MO on your planned travel date.

How does CheckMyBus find the best bus deals from Lafayette, LA to St. Louis, MO?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Lafayette, LA and St. Louis, MO. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Lafayette, LA to St. Louis, MO?

Prices and availability for 6 trips between Lafayette, LA and St. Louis, MO change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Lafayette, LA to St. Louis, MO

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Lafayette, LA and to St. Louis, MO

Here’s an overview of the most popular bus routes to Lafayette, LA and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Bus to St. Louis, MO from Pittsburgh Bus to St. Louis, MO from Pittsburgh
Popular Airport Shuttles to Lafayette, LA and to St. Louis, MO
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