Bus St. Louis, MO to Orlando, FL: Compare prices and save money

Compare all timetables for the bus from St. Louis, MO to Orlando, FL

Here is a selection of the cheapest bus trips from the schedule from St. Louis, MO to Orlando, FL from various bus operators like Greyhound US or FlixBus for the next days.

today

$112

tomorrow

$108

Sunday

$104

Monday

$104

Tuesday

$108

Wednesday

Thursday

$100

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	24h 35m	1:00 AM	St. Louis, MO	Gateway Station	2:35 AM	Orlando, FL	Bus Station	Economy	$112	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/23/2026 1:00:00 AM to Bus Station, Orlando, FL (USA) arriving at 10/24/2026 2:35:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 24h 35m
Greyhound US	28h 55m	9:00 AM	St. Louis, MO	Gateway Station	2:55 PM	Orlando, FL	Florida Mall	Economy	$112	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/23/2026 9:00:00 AM to Florida Mall, Orlando, FL (USA) arriving at 10/24/2026 2:55:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 28h 55m
FlixBus	19h 15m	11:45 PM	St. Louis, MO	Gateway Station	8:00 PM	Orlando, FL	Bus Station	Economy	$113	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 10/23/2026 11:45:00 PM to Bus Station, Orlando, FL (USA) arriving at 10/24/2026 8:00:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 19h 15m
FlixBus	23h 14m	11:45 PM	St. Louis, MO	Gateway Station	11:59 PM	Orlando, FL	Florida Mall	Economy	$113	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 10/23/2026 11:45:00 PM to Florida Mall, Orlando, FL (USA) arriving at 10/24/2026 11:59:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 23h 14m
FlixBus	23h 20m	4:00 PM	St. Louis, MO	Gateway Station	4:20 PM	Orlando, FL	Bus Station	Economy	$114	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 10/23/2026 4:00:00 PM to Bus Station, Orlando, FL (USA) arriving at 10/24/2026 4:20:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 23h 20m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	24h 35m	1:00 AM	St. Louis, MO	Gateway Station	2:35 AM	Orlando, FL	Bus Station	Economy	$108	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/24/2026 1:00:00 AM to Bus Station, Orlando, FL (USA) arriving at 10/25/2026 2:35:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 24h 35m
FlixBus	19h 15m	11:45 PM	St. Louis, MO	Gateway Station	8:00 PM	Orlando, FL	Bus Station	Economy	$108	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 10/24/2026 11:45:00 PM to Bus Station, Orlando, FL (USA) arriving at 10/25/2026 8:00:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 19h 15m
FlixBus	23h 14m	11:45 PM	St. Louis, MO	Gateway Station	11:59 PM	Orlando, FL	Florida Mall	Economy	$108	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 10/24/2026 11:45:00 PM to Florida Mall, Orlando, FL (USA) arriving at 10/25/2026 11:59:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 23h 14m
FlixBus	23h 20m	4:00 PM	St. Louis, MO	Gateway Station	4:20 PM	Orlando, FL	Bus Station	Economy	$109	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 10/24/2026 4:00:00 PM to Bus Station, Orlando, FL (USA) arriving at 10/25/2026 4:20:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 23h 20m
Greyhound US	28h 55m	9:00 AM	St. Louis, MO	Gateway Station	2:55 PM	Orlando, FL	Florida Mall	Economy	$114	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/24/2026 9:00:00 AM to Florida Mall, Orlando, FL (USA) arriving at 10/25/2026 2:55:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 28h 55m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	19h 15m	11:45 PM	St. Louis, MO	Gateway Station	8:00 PM	Orlando, FL	Bus Station	Economy	$104	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 10/25/2026 11:45:00 PM to Bus Station, Orlando, FL (USA) arriving at 10/26/2026 8:00:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 19h 15m
Greyhound US	20h 5m	9:00 AM	St. Louis, MO	Gateway Station	6:05 AM	Orlando, FL	Bus Station	Economy	$105	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/25/2026 9:00:00 AM to Bus Station, Orlando, FL (USA) arriving at 10/26/2026 6:05:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 20h 5m
FlixBus	23h 20m	4:00 PM	St. Louis, MO	Gateway Station	4:20 PM	Orlando, FL	Bus Station	Economy	$105	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 10/25/2026 4:00:00 PM to Bus Station, Orlando, FL (USA) arriving at 10/26/2026 4:20:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 23h 20m
FlixBus	23h 14m	11:45 PM	St. Louis, MO	Gateway Station	11:59 PM	Orlando, FL	Florida Mall	Economy	$105	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 10/25/2026 11:45:00 PM to Florida Mall, Orlando, FL (USA) arriving at 10/26/2026 11:59:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 23h 14m
Greyhound US	28h 55m	9:00 AM	St. Louis, MO	Gateway Station	2:55 PM	Orlando, FL	Florida Mall	Economy	$106	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/25/2026 9:00:00 AM to Florida Mall, Orlando, FL (USA) arriving at 10/26/2026 2:55:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 28h 55m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	24h 35m	1:00 AM	St. Louis, MO	Gateway Station	2:35 AM	Orlando, FL	Bus Station	Economy	$104	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/26/2026 1:00:00 AM to Bus Station, Orlando, FL (USA) arriving at 10/27/2026 2:35:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 24h 35m
Greyhound US	28h 55m	9:00 AM	St. Louis, MO	Gateway Station	2:55 PM	Orlando, FL	Florida Mall	Economy	$104	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/26/2026 9:00:00 AM to Florida Mall, Orlando, FL (USA) arriving at 10/27/2026 2:55:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 28h 55m
FlixBus	23h 20m	4:00 PM	St. Louis, MO	Gateway Station	4:20 PM	Orlando, FL	Bus Station	Economy	$104	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 10/26/2026 4:00:00 PM to Bus Station, Orlando, FL (USA) arriving at 10/27/2026 4:20:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 23h 20m
FlixBus	23h 14m	11:45 PM	St. Louis, MO	Gateway Station	11:59 PM	Orlando, FL	Florida Mall	Economy	$106	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 10/26/2026 11:45:00 PM to Florida Mall, Orlando, FL (USA) arriving at 10/27/2026 11:59:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 23h 14m
FlixBus	19h 15m	11:45 PM	St. Louis, MO	Gateway Station	8:00 PM	Orlando, FL	Bus Station	Economy	$108	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 10/26/2026 11:45:00 PM to Bus Station, Orlando, FL (USA) arriving at 10/27/2026 8:00:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 19h 15m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	24h 35m	1:00 AM	St. Louis, MO	Gateway Station	2:35 AM	Orlando, FL	Bus Station	Economy	$108	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/27/2026 1:00:00 AM to Bus Station, Orlando, FL (USA) arriving at 10/28/2026 2:35:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 24h 35m
Greyhound US	25h 35m	1:45 PM	St. Louis, MO	Gateway Station	4:20 PM	Orlando, FL	Bus Station	Economy	$109	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/27/2026 1:45:00 PM to Bus Station, Orlando, FL (USA) arriving at 10/28/2026 4:20:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 25h 35m
Greyhound US	21h 50m	9:00 AM	St. Louis, MO	Gateway Station	7:50 AM	Orlando, FL	Bus Station	Economy	$111	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/27/2026 9:00:00 AM to Bus Station, Orlando, FL (USA) arriving at 10/28/2026 7:50:00 AM. 50 Economy ticket for $111 per person are available. Travel duration is 21h 50m

Did you know that if you travel from St. Louis, MO to Orlando, FL via Atlanta, GA, you can save more than $14? You can find the corresponding connections below.
- Greyhound US
  
  20h 5m
  
  0
  
  9:00 AM
  
  St. Louis, MO
  Gateway Station
  
  9:40 PM
  
  Atlanta, GA
  Garnett Transit Station
  
  0
  
  Economy
  
  $48
  
  A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/28/2026 9:00:00 AM to Garnett Transit Station, Atlanta, GA (USA) arriving at 10/28/2026 9:40:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 11h 40m
- FlixBus
  
  7h 20m
  
  0
  
  10:45 PM
  
  Atlanta, GA
  Garnett Transit Station
  
  6:05 AM
  
  Orlando, FL
  Bus Station
  
  0
  
  Economy
  
  $46
  
  A Bus from FlixBus goes from Garnett Transit Station, Atlanta, GA (USA) at 10/28/2026 10:45:00 PM to Bus Station, Orlando, FL (USA) arriving at 10/29/2026 6:05:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 7h 20m
Travel Time is 2h 45m shorter, and you will save $14

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	27h 50m	1:00 AM	St. Louis, MO	Gateway Station	5:50 AM	Orlando, FL	Central Bus Station	Economy	$100	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/29/2026 1:00:00 AM to Central Bus Station, Orlando, FL (USA) arriving at 10/30/2026 5:50:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 27h 50m
Greyhound US	24h 35m	1:00 AM	St. Louis, MO	Gateway Station	2:35 AM	Orlando, FL	Central Bus Station	Economy	$103	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/29/2026 1:00:00 AM to Central Bus Station, Orlando, FL (USA) arriving at 10/30/2026 2:35:00 AM. 50 Economy ticket for $103 per person are available. Travel duration is 24h 35m
FlixBus	19h 15m	11:45 PM	St. Louis, MO	Gateway Station	8:00 PM	Orlando, FL	Bus Station	Economy	$104	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 10/29/2026 11:45:00 PM to Bus Station, Orlando, FL (USA) arriving at 10/30/2026 8:00:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 19h 15m
Greyhound US	26h 35m	1:45 PM	St. Louis, MO	Gateway Station	5:20 PM	Orlando, FL	Florida Mall	Economy	$105	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/29/2026 1:45:00 PM to Florida Mall, Orlando, FL (USA) arriving at 10/30/2026 5:20:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 26h 35m
FlixBus	23h 20m	4:00 PM	St. Louis, MO	Gateway Station	4:20 PM	Orlando, FL	Bus Station	Economy	$105	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 10/29/2026 4:00:00 PM to Bus Station, Orlando, FL (USA) arriving at 10/30/2026 4:20:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 23h 20m

Best Price Offer: The price for the cheapest bus from St. Louis, MO to Orlando, FL is $77 on 10/18/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between St. Louis, MO and Orlando, FL

See here how frequent the connections between St. Louis, MO and Orlando, FL are, during different times and days of the week.

Thursday is the busiest day, with more than 16 daily buses from St. Louis, MO to Orlando, FL. Tuesday has instead the fewest connections, with only 6 daily coaches between St. Louis, MO and Orlando, FL.

The busiest time of the day is the Morning, with 23 buses from St. Louis, MO to Orlando, FL, while Afternoon sees the fewest connections between St. Louis, MO and Orlando, FL, with 13 offers.

Facts about the bus from St. Louis, MO to Orlando, FL

Compare all providers like Greyhound US and FlixBus that travel 11 times every day by bus from St. Louis, MO to Orlando, FL in one click! Book your bus ticket from St. Louis, MO to Orlando, FL starting from $77!

Cheapest Bus	$77
Fastest Bus	20h 15m
Earliest Bus	1:00 AM
Latest Bus	11:45 PM
Daily Bus Routes	11 Ø
Distance	861.4 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from St. Louis, MO to Orlando, FL

Every day, 11 buses from 2 bus companies leave St. Louis, MO for Orlando, FL: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/23/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 10/18

Monday 10/19

Tuesday 10/20

Wednesday 10/21

Thursday 10/22

Friday 10/23

$112

Saturday 10/24

$108

Sunday 10/25

$104

Monday 10/26

$104

Tuesday 10/27

$108

Wednesday 10/28

Thursday 10/29

$104

Friday 10/30

$90

Saturday 10/31

$107

Sunday 11/01

$125

Monday 11/02

$96

Tuesday 11/03

$103

Wednesday 11/04

$108

Thursday 11/05

$132

Friday 11/06

$114

Saturday 11/07

$93

Sunday 11/08

$113

Monday 11/09

$120

Tuesday 11/10

$111

Wednesday 11/11

$102

Thursday 11/12

Friday 11/13

$120

Saturday 11/14

The cheapest time to travel from St. Louis, MO to Orlando, FL

See here on which day and which time of the day you can find the cheapest bus ticket from St. Louis, MO to Orlando, FL, for the next 30 days.

With a price starting from $89, Sunday is the cheapest day for a bus from St. Louis, MO to Orlando, FL. Tuesday instead is the most expensive day with prices starting from $103.

Night is the cheapest day time for bus tickets from St. Louis, MO to Orlando, FL, with $89. Afternoon is the most expensive time of the day with prices starting from $104.

How to save money travelling from St. Louis, MO to Orlando, FL

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from St. Louis, MO to Orlando, FL in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from St. Louis, MO to Orlando, FL, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from St. Louis, MO to Orlando, FL are also emptier.

Beloved bus companies from St. Louis, MO to Orlando, FL

These are the most booked bus companies between St. Louis, MO to Orlando, FL from our users.

Greyhound US from St. Louis, MO to Orlando, FL

Here you will find the key facts about the Greyhound US bus route St. Louis, MO to Orlando, FL:

Cheapest Price	$100
Fastest Bus	21h 5m
Earliest Bus	1:00 AM
Last Bus	1:45 PM
Daily Connections	6 Ø
Found on	10/21/2026

FlixBus from St. Louis, MO to Orlando, FL

Here you will find the key facts about the FlixBus bus route St. Louis, MO to Orlando, FL:

Cheapest Price	$104
Fastest Bus	20h 15m
Earliest Bus	4:00 PM
Last Bus	11:45 PM
Daily Connections	6 Ø
Found on	10/21/2026

All bus stations and stops in St. Louis, MO and Orlando, FL

In the map below, you can see where to find all bus stations in St. Louis, MO and Orlando, FL.

Gateway Station

S 15th St 430

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Lindbergh @ Hackberry NB Bus Stop

Bus Station

N John Young Pkwy 555

Florida Mall

Florida Mall Avenue 1602

RedCoach Station

Belle Isle

Universal Studio Orlando Resort

Universal Blvd 5800

UCF (University of Central Florida)

Libra Drive 3820

Service and Comfort on the bus from St. Louis, MO to Orlando, FL

Want to know which seat classes are available on the buses from St. Louis, MO to Orlando, FL? Or which bus companies serve the route St. Louis, MO to Orlando, FL? Below you will find answers to your questions.

FAQs about the St. Louis, MO to Orlando, FL bus

How much does a St. Louis, MO Orlando, FL bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $77 and takes 28h 50m to reach Orlando, FL. Compare offers to save money!

How much could I save by comparing buses from St. Louis, MO to Orlando, FL?

This route is offered by 2 companies with a range of ticket prices between $77 and $152. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Orlando, FL.

On average, how many connections are available from St. Louis, MO to Orlando, FL each day?

Every day, the St. Louis, MO to Orlando, FL bus route is served by approximately 11 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from St. Louis, MO to Orlando, FL take?

The fastest bus from St. Louis, MO to Orlando, FL is offered by FlixBus and takes 20h 15m. Bus tickets for this connection cost $113. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from St. Louis, MO to Orlando, FL?

The earliest bus arriving in Orlando, FL from St. Louis, MO starts at 1:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from St. Louis, MO to Orlando, FL?

The latest bus trip departing from St. Louis, MO for Orlando, FL starts at 11:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the St. Louis, MO Orlando, FL route?

When traveling by bus from St. Louis, MO to Orlando, FL, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between St. Louis, MO and Orlando, FL?

You can check all the direct connections between St. Louis, MO and Orlando, FL by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the St. Louis, MO to Orlando, FL bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the St. Louis, MO Orlando, FL bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the St. Louis, MO Orlando, FL bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from St. Louis, MO to Orlando, FL on your planned travel date.

How does CheckMyBus find the best bus deals from St. Louis, MO to Orlando, FL?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 11 daily trips between St. Louis, MO and Orlando, FL. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from St. Louis, MO to Orlando, FL?

Prices and availability for 11 trips between St. Louis, MO and Orlando, FL change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route St. Louis, MO to Orlando, FL

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to St. Louis, MO and to Orlando, FL

Here’s an overview of the most popular bus routes to St. Louis, MO and to Orlando, FL. Simply click on the connection of your choice, and you will find all the details about your bus route!