Bus Jacksonville, FL to Chicago: Compare prices and save money

Compare all timetables for the bus from Jacksonville, FL to Chicago

Here is a selection of the cheapest bus trips from the schedule from Jacksonville, FL to Chicago from various bus operators like FlixBus or Greyhound US for the next days.

today

$126

tomorrow

$129

Sunday

$133

Monday

$118

Tuesday

$115

Wednesday

$118

Thursday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	23h 45m	4:30 PM	Jacksonville, FL	Amtrak Train Station	3:15 PM	Chicago	Downtown Bus Station	Economy	$126	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 10/23/2026 4:30:00 PM to Downtown Bus Station, Chicago (USA) arriving at 10/24/2026 3:15:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 23h 45m
FlixBus	23h 45m	9:25 PM	Jacksonville, FL	Amtrak Train Station	8:10 PM	Chicago	Downtown Bus Station	Economy	$126	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 10/23/2026 9:25:00 PM to Downtown Bus Station, Chicago (USA) arriving at 10/24/2026 8:10:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 23h 45m
Greyhound US	27h 0m	9:30 AM	Jacksonville, FL	Amtrak Train Station	11:30 AM	Chicago	Downtown Bus Station	Economy	$129	A Bus from Greyhound US goes from Amtrak Train Station, Jacksonville, FL (USA) at 10/23/2026 9:30:00 AM to Downtown Bus Station, Chicago (USA) arriving at 10/24/2026 11:30:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 27h 0m
FlixBus	23h 55m	9:05 AM	Jacksonville, FL	Amtrak Train Station	8:00 AM	Chicago	Union Station	Economy	$131	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 10/23/2026 9:05:00 AM to Union Station, Chicago (USA) arriving at 10/24/2026 8:00:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 23h 55m
Greyhound US	29h 15m	9:30 AM	Jacksonville, FL	Amtrak Train Station	1:45 PM	Chicago	Union Station	Economy	$134	A Bus from Greyhound US goes from Amtrak Train Station, Jacksonville, FL (USA) at 10/23/2026 9:30:00 AM to Union Station, Chicago (USA) arriving at 10/24/2026 1:45:00 PM. 50 Economy ticket for $134 per person are available. Travel duration is 29h 15m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	27h 0m	9:30 AM	Jacksonville, FL	Amtrak Train Station	11:30 AM	Chicago	Downtown Bus Station	Economy	$129	A Bus from Greyhound US goes from Amtrak Train Station, Jacksonville, FL (USA) at 10/24/2026 9:30:00 AM to Downtown Bus Station, Chicago (USA) arriving at 10/25/2026 11:30:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 27h 0m
FlixBus	23h 55m	9:05 AM	Jacksonville, FL	Amtrak Train Station	8:00 AM	Chicago	Union Station	Economy	$130	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 10/24/2026 9:05:00 AM to Union Station, Chicago (USA) arriving at 10/25/2026 8:00:00 AM. 50 Economy ticket for $130 per person are available. Travel duration is 23h 55m
FlixBus	24h 20m	9:05 AM	Jacksonville, FL	Amtrak Train Station	8:25 AM	Chicago	Downtown Bus Station	Economy	$130	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 10/24/2026 9:05:00 AM to Downtown Bus Station, Chicago (USA) arriving at 10/25/2026 8:25:00 AM. 50 Economy ticket for $130 per person are available. Travel duration is 24h 20m
FlixBus	23h 45m	4:30 PM	Jacksonville, FL	Amtrak Train Station	3:15 PM	Chicago	Downtown Bus Station	Economy	$130	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 10/24/2026 4:30:00 PM to Downtown Bus Station, Chicago (USA) arriving at 10/25/2026 3:15:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 23h 45m
Greyhound US	29h 15m	9:30 AM	Jacksonville, FL	Amtrak Train Station	1:45 PM	Chicago	Union Station	Economy	$138	A Bus from Greyhound US goes from Amtrak Train Station, Jacksonville, FL (USA) at 10/24/2026 9:30:00 AM to Union Station, Chicago (USA) arriving at 10/25/2026 1:45:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 29h 15m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	23h 45m	4:30 PM	Jacksonville, FL	Amtrak Train Station	3:15 PM	Chicago	Downtown Bus Station	Economy	$133	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 10/25/2026 4:30:00 PM to Downtown Bus Station, Chicago (USA) arriving at 10/26/2026 3:15:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 23h 45m
FlixBus	23h 45m	9:25 PM	Jacksonville, FL	Amtrak Train Station	8:10 PM	Chicago	Downtown Bus Station	Economy	$133	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 10/25/2026 9:25:00 PM to Downtown Bus Station, Chicago (USA) arriving at 10/26/2026 8:10:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 23h 45m
Greyhound US	27h 0m	9:30 AM	Jacksonville, FL	Amtrak Train Station	11:30 AM	Chicago	Downtown Bus Station	Economy	$133	A Bus from Greyhound US goes from Amtrak Train Station, Jacksonville, FL (USA) at 10/25/2026 9:30:00 AM to Downtown Bus Station, Chicago (USA) arriving at 10/26/2026 11:30:00 AM. 50 Economy ticket for $133 per person are available. Travel duration is 27h 0m
Greyhound US	29h 15m	9:30 AM	Jacksonville, FL	Amtrak Train Station	1:45 PM	Chicago	Union Station	Economy	$136	A Bus from Greyhound US goes from Amtrak Train Station, Jacksonville, FL (USA) at 10/25/2026 9:30:00 AM to Union Station, Chicago (USA) arriving at 10/26/2026 1:45:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 29h 15m
FlixBus	23h 55m	9:05 AM	Jacksonville, FL	Amtrak Train Station	8:00 AM	Chicago	Union Station	Economy	$144	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 10/25/2026 9:05:00 AM to Union Station, Chicago (USA) arriving at 10/26/2026 8:00:00 AM. 50 Economy ticket for $144 per person are available. Travel duration is 23h 55m

Did you know that if you travel from Jacksonville, FL to Chicago via Lafayette, IN, you can save more than $14? You can find the corresponding connections below.
- FlixBus
  
  23h 55m
  
  0
  
  9:05 AM
  
  Jacksonville, FL
  Amtrak Train Station
  
  6:35 AM
  
  Lafayette, IN
  Next to CityBus Center
  
  0
  
  Economy
  
  $99
  
  A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 10/27/2026 9:05:00 AM to Next to CityBus Center, Lafayette, IN (USA) arriving at 10/28/2026 6:35:00 AM. 50 Economy ticket for $99 per person are available. Travel duration is 21h 30m
- Greyhound US
  
  2h 20m
  
  0
  
  6:40 AM
  
  Lafayette, IN
  Next to CityBus Center
  
  8:00 AM
  
  Chicago
  Canal & Van Buren
  
  0
  
  Economy
  
  $20
  
  A Bus from Greyhound US goes from Next to CityBus Center, Lafayette, IN (USA) at 10/28/2026 6:40:00 AM to Canal & Van Buren, Chicago (USA) arriving at 10/28/2026 8:00:00 AM. 50 Economy ticket for $20 per person are available. Travel duration is 2h 20m
Travel time is 1h 10m longer, but you will save $14

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	27h 5m	9:25 PM	Jacksonville, FL	Amtrak Train Station	11:30 PM	Chicago	95th Red Line Station	Economy	$118	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 10/26/2026 9:25:00 PM to 95th Red Line Station, Chicago (USA) arriving at 10/27/2026 11:30:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 27h 5m
Greyhound US	26h 35m	9:30 AM	Jacksonville, FL	Amtrak Train Station	11:05 AM	Chicago	95th Red Line Station	Economy	$118	A Bus from Greyhound US goes from Amtrak Train Station, Jacksonville, FL (USA) at 10/26/2026 9:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 10/27/2026 11:05:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 26h 35m
FlixBus	26h 15m	9:05 AM	Jacksonville, FL	Amtrak Train Station	10:20 AM	Chicago	95th Red Line Station	Economy	$123	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 10/26/2026 9:05:00 AM to 95th Red Line Station, Chicago (USA) arriving at 10/27/2026 10:20:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 26h 15m
FlixBus	23h 45m	9:25 PM	Jacksonville, FL	Amtrak Train Station	8:10 PM	Chicago	Downtown Bus Station	Economy	$133	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 10/26/2026 9:25:00 PM to Downtown Bus Station, Chicago (USA) arriving at 10/27/2026 8:10:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 23h 45m
Greyhound US	27h 0m	9:30 AM	Jacksonville, FL	Amtrak Train Station	11:30 AM	Chicago	Downtown Bus Station	Economy	$134	A Bus from Greyhound US goes from Amtrak Train Station, Jacksonville, FL (USA) at 10/26/2026 9:30:00 AM to Downtown Bus Station, Chicago (USA) arriving at 10/27/2026 11:30:00 AM. 50 Economy ticket for $134 per person are available. Travel duration is 27h 0m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	27h 5m	9:25 PM	Jacksonville, FL	Downtown Bus Stop	11:30 PM	Chicago	95th Red Line Station	Economy	$115	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 10/27/2026 9:25:00 PM to 95th Red Line Station, Chicago (USA) arriving at 10/28/2026 11:30:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 27h 5m
Greyhound US	26h 35m	9:30 AM	Jacksonville, FL	Downtown Bus Stop	11:05 AM	Chicago	95th Red Line Station	Economy	$115	A Bus from Greyhound US goes from Downtown Bus Stop, Jacksonville, FL (USA) at 10/27/2026 9:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 10/28/2026 11:05:00 AM. 50 Economy ticket for $115 per person are available. Travel duration is 26h 35m
Greyhound US	29h 25m	3:15 PM	Jacksonville, FL	Downtown Bus Stop	7:40 PM	Chicago	95th Red Line Station	Economy	$116	A Bus from Greyhound US goes from Downtown Bus Stop, Jacksonville, FL (USA) at 10/27/2026 3:15:00 PM to 95th Red Line Station, Chicago (USA) arriving at 10/28/2026 7:40:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 29h 25m
FlixBus	26h 15m	9:05 AM	Jacksonville, FL	Downtown Bus Stop	10:20 AM	Chicago	95th Red Line Station	Economy	$118	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 10/27/2026 9:05:00 AM to 95th Red Line Station, Chicago (USA) arriving at 10/28/2026 10:20:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 26h 15m
Greyhound US	25h 0m	3:15 PM	Jacksonville, FL	Downtown Bus Stop	3:15 PM	Chicago	Downtown Bus Station	Economy	$128	A Bus from Greyhound US goes from Downtown Bus Stop, Jacksonville, FL (USA) at 10/27/2026 3:15:00 PM to Downtown Bus Station, Chicago (USA) arriving at 10/28/2026 3:15:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 25h 0m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	26h 55m	4:30 PM	Jacksonville, FL	Amtrak Train Station	6:25 PM	Chicago	95th Red Line Station	Economy	$118	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 10/28/2026 4:30:00 PM to 95th Red Line Station, Chicago (USA) arriving at 10/29/2026 6:25:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 26h 55m
Greyhound US	26h 35m	9:30 AM	Jacksonville, FL	Amtrak Train Station	11:05 AM	Chicago	95th Red Line Station	Economy	$118	A Bus from Greyhound US goes from Amtrak Train Station, Jacksonville, FL (USA) at 10/28/2026 9:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 10/29/2026 11:05:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 26h 35m
FlixBus	27h 5m	9:25 PM	Jacksonville, FL	Amtrak Train Station	11:30 PM	Chicago	95th Red Line Station	Economy	$119	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 10/28/2026 9:25:00 PM to 95th Red Line Station, Chicago (USA) arriving at 10/29/2026 11:30:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 27h 5m
FlixBus	26h 15m	9:05 AM	Jacksonville, FL	Amtrak Train Station	10:20 AM	Chicago	95th Red Line Station	Economy	$129	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 10/28/2026 9:05:00 AM to 95th Red Line Station, Chicago (USA) arriving at 10/29/2026 10:20:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 26h 15m

Best Price Offer: The price for the cheapest bus from Jacksonville, FL to Chicago is $91 on 10/18/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Jacksonville, FL and Chicago

See here how frequent the connections between Jacksonville, FL and Chicago are, during different times and days of the week.

Tuesday is the busiest day, with more than 12 daily buses from Jacksonville, FL to Chicago. Wednesday has instead the fewest connections, with only 4 daily coaches between Jacksonville, FL and Chicago.

The busiest time of the day is the Morning, with 26 buses from Jacksonville, FL to Chicago, while Afternoon sees the fewest connections between Jacksonville, FL and Chicago, with 7 offers.

Facts about the bus from Jacksonville, FL to Chicago

Compare all providers like FlixBus and Greyhound US that travel 8 times every day by bus from Jacksonville, FL to Chicago in one click! Book your bus ticket from Jacksonville, FL to Chicago starting from $91!

Cheapest Bus	$91
Fastest Bus	22h 45m
Earliest Bus	9:05 AM
Latest Bus	9:25 PM
Daily Bus Routes	8 Ø
Distance	864.3 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Jacksonville, FL to Chicago

Every day, 8 buses from 2 bus companies leave Jacksonville, FL for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/23/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 10/18

Monday 10/19

Tuesday 10/20

Wednesday 10/21

Thursday 10/22

Friday 10/23

$126

Saturday 10/24

$129

Sunday 10/25

$133

Monday 10/26

$133

Tuesday 10/27

$115

Wednesday 10/28

$118

Thursday 10/29

Friday 10/30

Saturday 10/31

$140

Sunday 11/01

Monday 11/02

$126

Tuesday 11/03

$104

Wednesday 11/04

$101

Thursday 11/05

$109

Friday 11/06

$106

Saturday 11/07

Sunday 11/08

$122

Monday 11/09

$104

Tuesday 11/10

$119

Wednesday 11/11

$122

Thursday 11/12

Friday 11/13

Saturday 11/14

The cheapest time to travel from Jacksonville, FL to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from Jacksonville, FL to Chicago, for the next 30 days.

With a price starting from $100, Sunday is the cheapest day for a bus from Jacksonville, FL to Chicago. Friday instead is the most expensive day with prices starting from $106.

Evening is the cheapest day time for bus tickets from Jacksonville, FL to Chicago, with $115. Afternoon is the most expensive time of the day with prices starting from $116.

How to save money travelling from Jacksonville, FL to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Jacksonville, FL to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Jacksonville, FL to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Jacksonville, FL to Chicago are also emptier.

Beloved bus companies from Jacksonville, FL to Chicago

These are the most booked bus companies between Jacksonville, FL to Chicago from our users.

Greyhound US from Jacksonville, FL to Chicago

Here you will find the key facts about the Greyhound US bus route Jacksonville, FL to Chicago:

Cheapest Price	$115
Fastest Bus	24h 0m
Earliest Bus	9:30 AM
Last Bus	9:30 AM
Daily Connections	2 Ø
Found on	9/28/2026

All bus stations and stops in Jacksonville, FL and Chicago

In the map below, you can see where to find all bus stations in Jacksonville, FL and Chicago.

Downtown Bus Stop

West Forsyth Street 1111

Beaver St. & Ocean St. Bus Stop

Central Bus Station

Old St. Augustine Rd

Old St. Augustine Rd 10584-13

Southpoint Bus Stop

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Service and Comfort on the bus from Jacksonville, FL to Chicago

Want to know which seat classes are available on the buses from Jacksonville, FL to Chicago? Or which bus companies serve the route Jacksonville, FL to Chicago? Below you will find answers to your questions.

FAQs about the Jacksonville, FL to Chicago bus

How much does a Jacksonville, FL Chicago bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $91 and takes 26h 5m to reach Chicago. Compare offers to save money!

How much could I save by comparing buses from Jacksonville, FL to Chicago?

This route is offered by 2 companies with a range of ticket prices between $91 and $153. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.

On average, how many connections are available from Jacksonville, FL to Chicago each day?

Every day, the Jacksonville, FL to Chicago bus route is served by approximately 8 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Jacksonville, FL to Chicago take?

The fastest bus from Jacksonville, FL to Chicago is offered by FlixBus and takes 22h 45m. Bus tickets for this connection cost $126. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Jacksonville, FL to Chicago?

The earliest bus arriving in Chicago from Jacksonville, FL starts at 9:05 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Jacksonville, FL to Chicago?

The latest bus trip departing from Jacksonville, FL for Chicago starts at 9:25 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Jacksonville, FL Chicago route?

When traveling by bus from Jacksonville, FL to Chicago, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Jacksonville, FL and Chicago?

You can check all the direct connections between Jacksonville, FL and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Jacksonville, FL to Chicago bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Jacksonville, FL Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Jacksonville, FL Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Jacksonville, FL to Chicago on your planned travel date.

How does CheckMyBus find the best bus deals from Jacksonville, FL to Chicago?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 8 daily trips between Jacksonville, FL and Chicago. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Jacksonville, FL to Chicago?

Prices and availability for 8 trips between Jacksonville, FL and Chicago change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Jacksonville, FL to Chicago

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Jacksonville, FL and to Chicago

Here’s an overview of the most popular bus routes to Jacksonville, FL and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!