Bus San Antonio, TX to Chicago: Compare prices and save money

Compare all timetables for the bus from San Antonio, TX to Chicago

Here is a selection of the cheapest bus trips from the schedule from San Antonio, TX to Chicago from various bus operators like FlixBus, Greyhound Lines Mexico or Greyhound US for the next days.

today

$132

tomorrow

$113

Monday

$124

Tuesday

$111

Wednesday

$128

Thursday

$136

Friday

$141

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound Lines Mexico	27h 40m	1:30 AM	San Antonio, TX	Bus Station	5:10 AM	Chicago	95th Red Line Station	Economy	$132	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 10/24/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 10/25/2026 5:10:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 27h 40m
Greyhound Lines Mexico	30h 45m	4:20 AM	San Antonio, TX	Bus Station	11:05 AM	Chicago	95th Red Line Station	Economy	$132	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 10/24/2026 4:20:00 AM to 95th Red Line Station, Chicago (USA) arriving at 10/25/2026 11:05:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 30h 45m
FlixBus	31h 15m	9:55 PM	San Antonio, TX	Bus Station	5:10 AM	Chicago	95th Red Line Station	Economy	$132	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 10/24/2026 9:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 10/26/2026 5:10:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 31h 15m
FlixBus	49h 20m	9:45 AM	San Antonio, TX	Pearl District	11:05 AM	Chicago	95th Red Line Station	Economy	$138	A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 10/24/2026 9:45:00 AM to 95th Red Line Station, Chicago (USA) arriving at 10/26/2026 11:05:00 AM. 50 Economy ticket for $138 per person are available. Travel duration is 49h 20m
Greyhound US	30h 40m	4:20 AM	San Antonio, TX	Bus Station	11:00 AM	Chicago	95th Red Line Station	Economy	$185	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 10/24/2026 4:20:00 AM to 95th Red Line Station, Chicago (USA) arriving at 10/25/2026 11:00:00 AM. 50 Economy ticket for $185 per person are available. Travel duration is 30h 40m

Did you know that if you travel from San Antonio, TX to Chicago via Naperville, IL, you can save more than $21? You can find the corresponding connections below.
- Greyhound US
  
  33h 25m
  
  0
  
  1:30 AM
  
  San Antonio, TX
  Bus Station
  
  6:55 AM
  
  Naperville, IL
  Route 59 Metra Station
  
  0
  
  Economy
  
  $105
  
  A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 10/25/2026 1:30:00 AM to Route 59 Metra Station, Naperville, IL (USA) arriving at 10/26/2026 6:55:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 29h 25m
- Greyhound US
  
  0h 45m
  
  0
  
  10:10 AM
  
  Naperville, IL
  Route 59 Metra Station
  
  10:55 AM
  
  Chicago
  Downtown Bus Station
  
  0
  
  Economy
  
  $5
  
  A Bus from Greyhound US goes from Route 59 Metra Station, Naperville, IL (USA) at 10/26/2026 10:10:00 AM to Downtown Bus Station, Chicago (USA) arriving at 10/26/2026 10:55:00 AM. 50 Economy ticket for $5 per person are available. Travel duration is 0h 45m
Travel time is 5h 45m longer, but you will save $21

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	30h 45m	4:20 AM	San Antonio, TX	Bus Station	11:05 AM	Chicago	95th Red Line Station	Economy	$113	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 10/25/2026 4:20:00 AM to 95th Red Line Station, Chicago (USA) arriving at 10/26/2026 11:05:00 AM. 50 Economy ticket for $113 per person are available. Travel duration is 30h 45m
Greyhound US	27h 40m	1:30 AM	San Antonio, TX	Bus Station	5:10 AM	Chicago	95th Red Line Station	Economy	$114	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 10/25/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 10/26/2026 5:10:00 AM. 50 Economy ticket for $114 per person are available. Travel duration is 27h 40m
FlixBus	31h 15m	9:55 PM	San Antonio, TX	Bus Station	5:10 AM	Chicago	95th Red Line Station	Economy	$114	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 10/25/2026 9:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 10/27/2026 5:10:00 AM. 50 Economy ticket for $114 per person are available. Travel duration is 31h 15m
FlixBus	49h 20m	9:45 AM	San Antonio, TX	Pearl District	11:05 AM	Chicago	95th Red Line Station	Economy	$117	A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 10/25/2026 9:45:00 AM to 95th Red Line Station, Chicago (USA) arriving at 10/27/2026 11:05:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 49h 20m
Tornado Bus Company	24h 16m	11:05 AM	San Antonio, TX	Tornado Bus Company	11:21 AM	Chicago	California & 35th Street Bus Stop	Economy	$255	A Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 10/25/2026 11:05:00 AM to California & 35th Street Bus Stop, Chicago (USA) arriving at 10/26/2026 11:21:00 AM. 50 Economy ticket for $255 per person are available. Travel duration is 24h 16m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	27h 40m	1:30 AM	San Antonio, TX	Bus Station	5:10 AM	Chicago	95th Red Line Station	Economy	$124	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 10/26/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 10/27/2026 5:10:00 AM. 50 Economy ticket for $124 per person are available. Travel duration is 27h 40m
Greyhound US	30h 45m	4:20 AM	San Antonio, TX	Bus Station	11:05 AM	Chicago	95th Red Line Station	Economy	$124	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 10/26/2026 4:20:00 AM to 95th Red Line Station, Chicago (USA) arriving at 10/27/2026 11:05:00 AM. 50 Economy ticket for $124 per person are available. Travel duration is 30h 45m
FlixBus	36h 25m	9:55 PM	San Antonio, TX	Bus Station	10:20 AM	Chicago	95th Red Line Station	Economy	$125	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 10/26/2026 9:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 10/28/2026 10:20:00 AM. 50 Economy ticket for $125 per person are available. Travel duration is 36h 25m
FlixBus	39h 45m	7:45 AM	San Antonio, TX	Pearl District	11:30 PM	Chicago	95th Red Line Station	Economy	$125	A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 10/26/2026 7:45:00 AM to 95th Red Line Station, Chicago (USA) arriving at 10/27/2026 11:30:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 39h 45m
Greyhound US	31h 10m	4:20 AM	San Antonio, TX	Bus Station	11:30 AM	Chicago	Downtown Bus Station	Economy	$126	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 10/26/2026 4:20:00 AM to Downtown Bus Station, Chicago (USA) arriving at 10/27/2026 11:30:00 AM. 50 Economy ticket for $126 per person are available. Travel duration is 31h 10m

Did you know that if you travel from San Antonio, TX to Chicago via Naperville, IL, you can save more than $13? You can find the corresponding connections below.
- Greyhound US
  
  33h 25m
  
  0
  
  1:30 AM
  
  San Antonio, TX
  Bus Station
  
  6:55 AM
  
  Naperville, IL
  Route 59 Metra Station
  
  0
  
  Economy
  
  $105
  
  A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 10/25/2026 1:30:00 AM to Route 59 Metra Station, Naperville, IL (USA) arriving at 10/26/2026 6:55:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 29h 25m
- Greyhound US
  
  0h 45m
  
  0
  
  10:10 AM
  
  Naperville, IL
  Route 59 Metra Station
  
  10:55 AM
  
  Chicago
  Downtown Bus Station
  
  0
  
  Economy
  
  $5
  
  A Bus from Greyhound US goes from Route 59 Metra Station, Naperville, IL (USA) at 10/26/2026 10:10:00 AM to Downtown Bus Station, Chicago (USA) arriving at 10/26/2026 10:55:00 AM. 50 Economy ticket for $5 per person are available. Travel duration is 0h 45m
Travel time is 5h 45m longer, but you will save $13

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	39h 20m	4:20 AM	San Antonio, TX	Bus Station	7:40 PM	Chicago	95th Red Line Station	Economy	$111	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 10/27/2026 4:20:00 AM to 95th Red Line Station, Chicago (USA) arriving at 10/28/2026 7:40:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 39h 20m
Greyhound US	35h 31m	11:59 AM	San Antonio, TX	Bus Station	11:30 PM	Chicago	95th Red Line Station	Economy	$111	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 10/27/2026 11:59:00 AM to 95th Red Line Station, Chicago (USA) arriving at 10/28/2026 11:30:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 35h 31m
FlixBus	36h 25m	9:55 PM	San Antonio, TX	Bus Station	10:20 AM	Chicago	95th Red Line Station	Economy	$113	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 10/27/2026 9:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 10/29/2026 10:20:00 AM. 50 Economy ticket for $113 per person are available. Travel duration is 36h 25m
FlixBus	34h 5m	9:55 PM	San Antonio, TX	Bus Station	8:00 AM	Chicago	Canal & Van Buren	Economy	$128	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 10/27/2026 9:55:00 PM to Canal & Van Buren, Chicago (USA) arriving at 10/29/2026 8:00:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 34h 5m
Tornado Bus Company	23h 48m	11:05 AM	San Antonio, TX	Tornado Bus Company	10:52 AM	Chicago	California & 35th Street Bus Stop	Economy	$255	A Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 10/27/2026 11:05:00 AM to California & 35th Street Bus Stop, Chicago (USA) arriving at 10/28/2026 10:52:30 AM. 50 Economy ticket for $255 per person are available. Travel duration is 23h 48m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound Lines Mexico	32h 50m	1:30 AM	San Antonio, TX	Bus Station	10:20 AM	Chicago	95th Red Line Station	Economy	$128	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 10/28/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 10/29/2026 10:20:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 32h 50m
FlixBus	32h 10m	9:00 PM	San Antonio, TX	Bus Station	5:10 AM	Chicago	95th Red Line Station	Economy	$128	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 10/28/2026 9:00:00 PM to 95th Red Line Station, Chicago (USA) arriving at 10/30/2026 5:10:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 32h 10m
Greyhound Lines Mexico	38h 5m	4:20 AM	San Antonio, TX	Bus Station	6:25 PM	Chicago	95th Red Line Station	Economy	$129	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 10/28/2026 4:20:00 AM to 95th Red Line Station, Chicago (USA) arriving at 10/29/2026 6:25:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 38h 5m
Greyhound Lines Mexico	35h 31m	11:59 AM	San Antonio, TX	Bus Station	11:30 PM	Chicago	95th Red Line Station	Economy	$131	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 10/28/2026 11:59:00 AM to 95th Red Line Station, Chicago (USA) arriving at 10/29/2026 11:30:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 35h 31m
FlixBus	31h 20m	9:00 PM	San Antonio, TX	Bus Station	4:20 AM	Chicago	Downtown Bus Station	Economy	$133	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 10/28/2026 9:00:00 PM to Downtown Bus Station, Chicago (USA) arriving at 10/30/2026 4:20:00 AM. 50 Economy ticket for $133 per person are available. Travel duration is 31h 20m

Did you know that if you travel from San Antonio, TX to Chicago via Naperville, IL, you can save more than $17? You can find the corresponding connections below.
- Greyhound US
  
  33h 25m
  
  0
  
  1:30 AM
  
  San Antonio, TX
  Bus Station
  
  6:55 AM
  
  Naperville, IL
  Route 59 Metra Station
  
  0
  
  Economy
  
  $105
  
  A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 10/25/2026 1:30:00 AM to Route 59 Metra Station, Naperville, IL (USA) arriving at 10/26/2026 6:55:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 29h 25m
- Greyhound US
  
  0h 45m
  
  0
  
  10:10 AM
  
  Naperville, IL
  Route 59 Metra Station
  
  10:55 AM
  
  Chicago
  Downtown Bus Station
  
  0
  
  Economy
  
  $5
  
  A Bus from Greyhound US goes from Route 59 Metra Station, Naperville, IL (USA) at 10/26/2026 10:10:00 AM to Downtown Bus Station, Chicago (USA) arriving at 10/26/2026 10:55:00 AM. 50 Economy ticket for $5 per person are available. Travel duration is 0h 45m
Travel time is 2h 5m longer, but you will save $17

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound Lines Mexico	27h 40m	1:30 AM	San Antonio, TX	Bus Station	5:10 AM	Chicago	95th Red Line Station	Economy	$136	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 10/29/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 10/30/2026 5:10:00 AM. 50 Economy ticket for $136 per person are available. Travel duration is 27h 40m
FlixBus	32h 10m	9:00 PM	San Antonio, TX	Bus Station	5:10 AM	Chicago	95th Red Line Station	Economy	$136	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 10/29/2026 9:00:00 PM to 95th Red Line Station, Chicago (USA) arriving at 10/31/2026 5:10:00 AM. 50 Economy ticket for $136 per person are available. Travel duration is 32h 10m
FlixBus	34h 55m	7:30 AM	San Antonio, TX	Bus Station	6:25 PM	Chicago	95th Red Line Station	Economy	$138	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 10/29/2026 7:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 10/30/2026 6:25:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 34h 55m
FlixBus	34h 40m	7:45 AM	San Antonio, TX	Pearl District	6:25 PM	Chicago	95th Red Line Station	Economy	$138	A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 10/29/2026 7:45:00 AM to 95th Red Line Station, Chicago (USA) arriving at 10/30/2026 6:25:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 34h 40m
Greyhound Lines Mexico	35h 31m	11:59 AM	San Antonio, TX	Bus Station	11:30 PM	Chicago	95th Red Line Station	Economy	$140	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 10/29/2026 11:59:00 AM to 95th Red Line Station, Chicago (USA) arriving at 10/30/2026 11:30:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 35h 31m

Did you know that if you travel from San Antonio, TX to Chicago via Naperville, IL, you can save more than $25? You can find the corresponding connections below.
- Greyhound US
  
  33h 25m
  
  0
  
  1:30 AM
  
  San Antonio, TX
  Bus Station
  
  6:55 AM
  
  Naperville, IL
  Route 59 Metra Station
  
  0
  
  Economy
  
  $105
  
  A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 10/25/2026 1:30:00 AM to Route 59 Metra Station, Naperville, IL (USA) arriving at 10/26/2026 6:55:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 29h 25m
- Greyhound US
  
  0h 45m
  
  0
  
  10:10 AM
  
  Naperville, IL
  Route 59 Metra Station
  
  10:55 AM
  
  Chicago
  Downtown Bus Station
  
  0
  
  Economy
  
  $5
  
  A Bus from Greyhound US goes from Route 59 Metra Station, Naperville, IL (USA) at 10/26/2026 10:10:00 AM to Downtown Bus Station, Chicago (USA) arriving at 10/26/2026 10:55:00 AM. 50 Economy ticket for $5 per person are available. Travel duration is 0h 45m
Travel time is 5h 45m longer, but you will save $25

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound Lines Mexico	26h 50m	1:30 AM	San Antonio, TX	Bus Station	4:20 AM	Chicago	Downtown Bus Station	Economy	$141	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 10/30/2026 1:30:00 AM to Downtown Bus Station, Chicago (USA) arriving at 10/31/2026 4:20:00 AM. 50 Economy ticket for $141 per person are available. Travel duration is 26h 50m
FlixBus	34h 5m	9:55 PM	San Antonio, TX	Bus Station	7:00 AM	Chicago	Union Station	Economy	$141	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 10/30/2026 9:55:00 PM to Union Station, Chicago (USA) arriving at 11/1/2026 7:00:00 AM. 50 Economy ticket for $141 per person are available. Travel duration is 34h 5m
FlixBus	30h 25m	9:55 PM	San Antonio, TX	Bus Station	3:20 AM	Chicago	Downtown Bus Station	Economy	$141	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 10/30/2026 9:55:00 PM to Downtown Bus Station, Chicago (USA) arriving at 11/1/2026 3:20:00 AM. 50 Economy ticket for $141 per person are available. Travel duration is 30h 25m
Greyhound Lines Mexico	32h 11m	11:59 AM	San Antonio, TX	Bus Station	8:10 PM	Chicago	Downtown Bus Station	Economy	$144	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 10/30/2026 11:59:00 AM to Downtown Bus Station, Chicago (USA) arriving at 10/31/2026 8:10:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 32h 11m
FlixBus	48h 15m	7:45 AM	San Antonio, TX	Pearl District	7:00 AM	Chicago	Union Station	Economy	$146	A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 10/30/2026 7:45:00 AM to Union Station, Chicago (USA) arriving at 11/1/2026 7:00:00 AM. 50 Economy ticket for $146 per person are available. Travel duration is 48h 15m

Did you know that if you travel from San Antonio, TX to Chicago via Naperville, IL, you can save more than $30? You can find the corresponding connections below.
- Greyhound US
  
  33h 25m
  
  0
  
  1:30 AM
  
  San Antonio, TX
  Bus Station
  
  6:55 AM
  
  Naperville, IL
  Route 59 Metra Station
  
  0
  
  Economy
  
  $105
  
  A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 10/25/2026 1:30:00 AM to Route 59 Metra Station, Naperville, IL (USA) arriving at 10/26/2026 6:55:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 29h 25m
- Greyhound US
  
  0h 45m
  
  0
  
  10:10 AM
  
  Naperville, IL
  Route 59 Metra Station
  
  10:55 AM
  
  Chicago
  Downtown Bus Station
  
  0
  
  Economy
  
  $5
  
  A Bus from Greyhound US goes from Route 59 Metra Station, Naperville, IL (USA) at 10/26/2026 10:10:00 AM to Downtown Bus Station, Chicago (USA) arriving at 10/26/2026 10:55:00 AM. 50 Economy ticket for $5 per person are available. Travel duration is 0h 45m
Travel time is 6h 35m longer, but you will save $30

Best Price Offer: The price for the cheapest bus from San Antonio, TX to Chicago is $97 on 10/18/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between San Antonio, TX and Chicago

See here how frequent the connections between San Antonio, TX and Chicago are, during different times and days of the week.

Saturday is the busiest day, with more than 41 daily buses from San Antonio, TX to Chicago. Thursday has instead the fewest connections, with only 6 daily coaches between San Antonio, TX and Chicago.

The busiest time of the day is the Morning, with 65 buses from San Antonio, TX to Chicago, while Evening sees the fewest connections between San Antonio, TX and Chicago, with 24 offers.

Facts about the bus from San Antonio, TX to Chicago

Compare all providers like FlixBus, Greyhound Lines Mexico and Greyhound US that travel 19 times every day by bus from San Antonio, TX to Chicago in one click! Book your bus ticket from San Antonio, TX to Chicago starting from $97!

Cheapest Bus	$97
Fastest Bus	23h 17m
Earliest Bus	1:30 AM
Latest Bus	9:55 PM
Daily Bus Routes	19 Ø
Distance	1,052.2 miles
Bus Companies	FlixBus, Greyhound Lines Mexico, Greyhound US and Tornado Bus Company

Cheapest bus connections from San Antonio, TX to Chicago

Every day, 19 buses from 4 bus companies leave San Antonio, TX for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/24/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 10/18

Monday 10/19

Tuesday 10/20

Wednesday 10/21

Thursday 10/22

Friday 10/23

Saturday 10/24

$178

Sunday 10/25

$113

Monday 10/26

$124

Tuesday 10/27

$126

Wednesday 10/28

$133

Thursday 10/29

$136

Friday 10/30

$141

Saturday 10/31

$132

Sunday 11/01

Monday 11/02

Tuesday 11/03

$124

Wednesday 11/04

Thursday 11/05

$124

Friday 11/06

$112

Saturday 11/07

Sunday 11/08

$120

Monday 11/09

$116

Tuesday 11/10

Wednesday 11/11

$110

Thursday 11/12

$110

Friday 11/13

Saturday 11/14

The cheapest time to travel from San Antonio, TX to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from San Antonio, TX to Chicago, for the next 30 days.

With a price starting from $109, Monday is the cheapest day for a bus from San Antonio, TX to Chicago. Saturday instead is the most expensive day with prices starting from $131.

Night is the cheapest day time for bus tickets from San Antonio, TX to Chicago, with $109. Evening is the most expensive time of the day with prices starting from $113.

How to save money travelling from San Antonio, TX to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Antonio, TX to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Antonio, TX to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Antonio, TX to Chicago are also emptier.

Beloved bus companies from San Antonio, TX to Chicago

These are the most booked bus companies between San Antonio, TX to Chicago from our users.

Greyhound Lines Mexico from San Antonio, TX to Chicago

Here you will find the key facts about the Greyhound Lines Mexico bus route San Antonio, TX to Chicago:

Cheapest Price	$117
Fastest Bus	26h 50m
Earliest Bus	1:30 AM
Last Bus	11:59 AM
Daily Connections	4 Ø
Found on	9/30/2026

FlixBus from San Antonio, TX to Chicago

Here you will find the key facts about the FlixBus bus route San Antonio, TX to Chicago:

Cheapest Price	$113
Fastest Bus	29h 25m
Earliest Bus	7:30 AM
Last Bus	9:55 PM
Daily Connections	9 Ø
Found on	10/22/2026

All bus stations and stops in San Antonio, TX and Chicago

In the map below, you can see where to find all bus stations in San Antonio, TX and Chicago.

Bus Station

N St Mary's St 500

San Antonio

Pearl District

Avenue A 699-599

Commerce & Bowie Bus Stop

W. Southcross & Buffalo Bus Stop

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from San Antonio, TX to Chicago? Compare all modes of transports from San Antonio, TX to Chicago.

Service and Comfort on the bus from San Antonio, TX to Chicago

Want to know which seat classes are available on the buses from San Antonio, TX to Chicago? Or which bus companies serve the route San Antonio, TX to Chicago? Below you will find answers to your questions.

FAQs about the San Antonio, TX to Chicago bus

How much does a San Antonio, TX Chicago bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $97 and takes 39h 20m to reach Chicago. Compare offers to save money!

How much could I save by comparing buses from San Antonio, TX to Chicago?

This route is offered by 4 companies with a range of ticket prices between $97 and $265. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.

On average, how many connections are available from San Antonio, TX to Chicago each day?

Every day, the San Antonio, TX to Chicago bus route is served by approximately 19 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Antonio, TX to Chicago take?

The fastest bus from San Antonio, TX to Chicago is offered by Tornado Bus Company and takes 23h 17m. Bus tickets for this connection cost $255. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Antonio, TX to Chicago?

The earliest bus arriving in Chicago from San Antonio, TX starts at 1:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Antonio, TX to Chicago?

The latest bus trip departing from San Antonio, TX for Chicago starts at 9:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Antonio, TX Chicago route?

When traveling by bus from San Antonio, TX to Chicago, passengers can travel with FlixBus, Greyhound Lines Mexico and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Antonio, TX and Chicago?

You can check all the direct connections between San Antonio, TX and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound Lines Mexico and Greyhound US.

What can I take with me on the San Antonio, TX to Chicago bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Antonio, TX Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Antonio, TX Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Antonio, TX to Chicago on your planned travel date.

How does CheckMyBus find the best bus deals from San Antonio, TX to Chicago?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 19 daily trips between San Antonio, TX and Chicago. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Antonio, TX to Chicago?

Prices and availability for 19 trips between San Antonio, TX and Chicago change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Antonio, TX to Chicago

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Antonio, TX and to Chicago

Here’s an overview of the most popular bus routes to San Antonio, TX and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!