Bus Indianapolis to Columbia, MO: Compare prices and save money

Compare all timetables for the bus from Indianapolis to Columbia, MO

Here is a selection of the cheapest bus trips from the schedule from Indianapolis to Columbia, MO from various bus operators like Greyhound US or FlixBus for the next days.

today

$40

tomorrow

$44

Thursday

Friday

$57

Saturday

Sunday

$54

Monday

$51

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	11h 10m	4:50 AM	Indianapolis	Central Bus Station	3:00 PM	Columbia, MO	Red Thread	Economy	$40	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 8/25/2026 4:50:00 AM to Red Thread, Columbia, MO (USA) arriving at 8/25/2026 3:00:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 11h 10m
Greyhound US	9h 35m	11:05 AM	Indianapolis	Central Bus Station	7:40 PM	Columbia, MO	Red Thread	Economy	$40	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 8/25/2026 11:05:00 AM to Red Thread, Columbia, MO (USA) arriving at 8/25/2026 7:40:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 9h 35m
Greyhound US	13h 50m	7:55 PM	Indianapolis	Central Bus Station	8:45 AM	Columbia, MO	Red Thread	Economy	$40	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 8/25/2026 7:55:00 PM to Red Thread, Columbia, MO (USA) arriving at 8/26/2026 8:45:00 AM. 50 Economy ticket for $40 per person are available. Travel duration is 13h 50m
Greyhound US	10h 40m	4:50 AM	Indianapolis	Central Bus Station	2:30 PM	Columbia, MO	Bus Stop	Economy	$40	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 8/25/2026 4:50:00 AM to Bus Stop, Columbia, MO (USA) arriving at 8/25/2026 2:30:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 10h 40m
Greyhound US	13h 25m	7:55 PM	Indianapolis	Central Bus Station	8:20 AM	Columbia, MO	Bus Stop	Economy	$41	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 8/25/2026 7:55:00 PM to Bus Stop, Columbia, MO (USA) arriving at 8/26/2026 8:20:00 AM. 50 Economy ticket for $41 per person are available. Travel duration is 13h 25m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	11h 10m	4:50 AM	Indianapolis	Central Bus Station	3:00 PM	Columbia, MO	Red Thread	Economy	$44	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 8/26/2026 4:50:00 AM to Red Thread, Columbia, MO (USA) arriving at 8/26/2026 3:00:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 11h 10m
Greyhound US	9h 35m	11:05 AM	Indianapolis	Central Bus Station	7:40 PM	Columbia, MO	Red Thread	Economy	$44	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 8/26/2026 11:05:00 AM to Red Thread, Columbia, MO (USA) arriving at 8/26/2026 7:40:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 9h 35m
Greyhound US	10h 40m	4:50 AM	Indianapolis	Central Bus Station	2:30 PM	Columbia, MO	Bus Stop	Economy	$44	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 8/26/2026 4:50:00 AM to Bus Stop, Columbia, MO (USA) arriving at 8/26/2026 2:30:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 10h 40m
Greyhound US	13h 25m	7:55 PM	Indianapolis	Central Bus Station	8:20 AM	Columbia, MO	Bus Stop	Economy	$44	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 8/26/2026 7:55:00 PM to Bus Stop, Columbia, MO (USA) arriving at 8/27/2026 8:20:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 13h 25m
Greyhound US	13h 50m	7:55 PM	Indianapolis	Central Bus Station	8:45 AM	Columbia, MO	Red Thread	Economy	$45	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 8/26/2026 7:55:00 PM to Red Thread, Columbia, MO (USA) arriving at 8/27/2026 8:45:00 AM. 50 Economy ticket for $45 per person are available. Travel duration is 13h 50m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	17h 25m	3:15 AM	Indianapolis	Washington / Delaware	7:40 PM	Columbia, MO	Red Thread	Economy	$57	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 8/28/2026 3:15:00 AM to Red Thread, Columbia, MO (USA) arriving at 8/28/2026 7:40:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 17h 25m
Greyhound US	10h 40m	4:50 AM	Indianapolis	Central Bus Station	2:30 PM	Columbia, MO	Bus Stop	Economy	$57	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 8/28/2026 4:50:00 AM to Bus Stop, Columbia, MO (USA) arriving at 8/28/2026 2:30:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 10h 40m
Greyhound US	11h 10m	4:50 AM	Indianapolis	Central Bus Station	3:00 PM	Columbia, MO	Red Thread	Economy	$57	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 8/28/2026 4:50:00 AM to Red Thread, Columbia, MO (USA) arriving at 8/28/2026 3:00:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 11h 10m
Greyhound US	9h 35m	11:05 AM	Indianapolis	Central Bus Station	7:40 PM	Columbia, MO	Red Thread	Economy	$57	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 8/28/2026 11:05:00 AM to Red Thread, Columbia, MO (USA) arriving at 8/28/2026 7:40:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 9h 35m

Did you know that if you travel from Indianapolis to Columbia, MO via St. Louis, MO, you can save more than $8? You can find the corresponding connections below.
- Greyhound US
  
  9h 35m
  
  0
  
  11:05 AM
  
  Indianapolis
  Central Bus Station
  
  3:10 PM
  
  St. Louis, MO
  Gateway Station
  
  0
  
  Economy
  
  $29
  
  A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 8/26/2026 11:05:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 8/26/2026 3:10:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 5h 5m
- Greyhound US
  
  2h 25m
  
  0
  
  5:15 PM
  
  St. Louis, MO
  Gateway Station
  
  7:40 PM
  
  Columbia, MO
  Red Thread
  
  0
  
  Economy
  
  $20
  
  A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 8/26/2026 5:15:00 PM to Red Thread, Columbia, MO (USA) arriving at 8/26/2026 7:40:00 PM. 50 Economy ticket for $20 per person are available. Travel duration is 2h 25m
Travel time is 1h 0m longer, but you will save $8

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	11h 10m	4:50 AM	Indianapolis	Central Bus Station	3:00 PM	Columbia, MO	Red Thread	Economy	$54	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 8/30/2026 4:50:00 AM to Red Thread, Columbia, MO (USA) arriving at 8/30/2026 3:00:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 11h 10m
Greyhound US	9h 35m	11:05 AM	Indianapolis	Central Bus Station	7:40 PM	Columbia, MO	Red Thread	Economy	$54	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 8/30/2026 11:05:00 AM to Red Thread, Columbia, MO (USA) arriving at 8/30/2026 7:40:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 9h 35m
Greyhound US	10h 40m	4:50 AM	Indianapolis	Central Bus Station	2:30 PM	Columbia, MO	Bus Stop	Economy	$54	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 8/30/2026 4:50:00 AM to Bus Stop, Columbia, MO (USA) arriving at 8/30/2026 2:30:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 10h 40m
FlixBus	17h 25m	3:15 AM	Indianapolis	Washington / Delaware	7:40 PM	Columbia, MO	Red Thread	Economy	$59	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 8/30/2026 3:15:00 AM to Red Thread, Columbia, MO (USA) arriving at 8/30/2026 7:40:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 17h 25m

Did you know that if you travel from Indianapolis to Columbia, MO via St. Louis, MO, you can save more than $5? You can find the corresponding connections below.
- Greyhound US
  
  9h 35m
  
  0
  
  11:05 AM
  
  Indianapolis
  Central Bus Station
  
  3:10 PM
  
  St. Louis, MO
  Gateway Station
  
  0
  
  Economy
  
  $29
  
  A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 8/26/2026 11:05:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 8/26/2026 3:10:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 5h 5m
- Greyhound US
  
  2h 25m
  
  0
  
  5:15 PM
  
  St. Louis, MO
  Gateway Station
  
  7:40 PM
  
  Columbia, MO
  Red Thread
  
  0
  
  Economy
  
  $20
  
  A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 8/26/2026 5:15:00 PM to Red Thread, Columbia, MO (USA) arriving at 8/26/2026 7:40:00 PM. 50 Economy ticket for $20 per person are available. Travel duration is 2h 25m
Travel time is 1h 0m longer, but you will save $5

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	17h 25m	3:15 AM	Indianapolis	Washington / Delaware	7:40 PM	Columbia, MO	Red Thread	Economy	$51	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 8/31/2026 3:15:00 AM to Red Thread, Columbia, MO (USA) arriving at 8/31/2026 7:40:00 PM. 50 Economy ticket for $51 per person are available. Travel duration is 17h 25m
Greyhound US	10h 40m	4:50 AM	Indianapolis	Central Bus Station	2:30 PM	Columbia, MO	Bus Stop	Economy	$51	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 8/31/2026 4:50:00 AM to Bus Stop, Columbia, MO (USA) arriving at 8/31/2026 2:30:00 PM. 50 Economy ticket for $51 per person are available. Travel duration is 10h 40m
Greyhound US	11h 10m	4:50 AM	Indianapolis	Central Bus Station	3:00 PM	Columbia, MO	Red Thread	Economy	$51	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 8/31/2026 4:50:00 AM to Red Thread, Columbia, MO (USA) arriving at 8/31/2026 3:00:00 PM. 50 Economy ticket for $51 per person are available. Travel duration is 11h 10m
Greyhound US	9h 35m	11:05 AM	Indianapolis	Central Bus Station	7:40 PM	Columbia, MO	Red Thread	Economy	$51	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 8/31/2026 11:05:00 AM to Red Thread, Columbia, MO (USA) arriving at 8/31/2026 7:40:00 PM. 50 Economy ticket for $51 per person are available. Travel duration is 9h 35m

Best Price Offer: The price for the cheapest bus from Indianapolis to Columbia, MO is $40 on 8/25/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Indianapolis and Columbia, MO

See here how frequent the connections between Indianapolis and Columbia, MO are, during different times and days of the week.

Sunday is the busiest day, with more than 11 daily buses from Indianapolis to Columbia, MO. Tuesday has instead the fewest connections, with only 5 daily coaches between Indianapolis and Columbia, MO.

The busiest time of the day is the Night, with 15 buses from Indianapolis to Columbia, MO, while Morning sees the fewest connections between Indianapolis and Columbia, MO, with 6 offers.

Facts about the bus from Indianapolis to Columbia, MO

Compare all providers like Greyhound US and FlixBus that travel 6 times every day by bus from Indianapolis to Columbia, MO in one click! Book your bus ticket from Indianapolis to Columbia, MO starting from $40!

Cheapest Bus	$40
Fastest Bus	8h 35m
Earliest Bus	4:50 AM
Latest Bus	7:55 PM
Daily Bus Routes	6 Ø
Distance	334.5 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Indianapolis to Columbia, MO

Every day, 6 buses from 2 bus companies leave Indianapolis for Columbia, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 08/25/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 08/23

Monday 08/24

Tuesday 08/25

$40

Wednesday 08/26

$44

Thursday 08/27

Friday 08/28

$57

Saturday 08/29

Sunday 08/30

$54

Monday 08/31

$51

Tuesday 09/01

$53

Wednesday 09/02

Thursday 09/03

$51

Friday 09/04

$58

Saturday 09/05

$55

Sunday 09/06

$59

Monday 09/07

Tuesday 09/08

Wednesday 09/09

Thursday 09/10

$45

Friday 09/11

Saturday 09/12

Sunday 09/13

$57

Monday 09/14

$45

Tuesday 09/15

Wednesday 09/16

$48

Thursday 09/17

Friday 09/18

$51

Saturday 09/19

The cheapest time to travel from Indianapolis to Columbia, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Indianapolis to Columbia, MO, for the next 30 days.

With a price starting from $40, Tuesday is the cheapest day for a bus from Indianapolis to Columbia, MO. Sunday instead is the most expensive day with prices starting from $54.

Night is the cheapest day time for bus tickets from Indianapolis to Columbia, MO, with $40. Morning is the most expensive time of the day with prices starting from $40.

How to save money travelling from Indianapolis to Columbia, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Indianapolis to Columbia, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Indianapolis to Columbia, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Indianapolis to Columbia, MO are also emptier.

All bus stations and stops in Indianapolis and Columbia, MO

In the map below, you can see where to find all bus stations in Indianapolis and Columbia, MO.

Mile Square

Monument Circle 2250

Washington / Delaware

E Washington St between N Delaware St and N Alabama St

Central Bus Station

Greyhound Bus Station

S Illinois St 350

S Keystone Avenue

S Keystone Avenue 3649

Bus Stop

N 10th St 198

Red Thread

Highway 40 W 6401

University

Fellows Pl 1301-1349

Service and Comfort on the bus from Indianapolis to Columbia, MO

Want to know which seat classes are available on the buses from Indianapolis to Columbia, MO? Or which bus companies serve the route Indianapolis to Columbia, MO? Below you will find answers to your questions.

FAQs about the Indianapolis to Columbia, MO bus

How much does a Indianapolis Columbia, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $40 and takes 9h 40m to reach Columbia, MO. Compare offers to save money!

How much could I save by comparing buses from Indianapolis to Columbia, MO?

This route is offered by 2 companies with a range of ticket prices between $40 and $59. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Columbia, MO.

On average, how many connections are available from Indianapolis to Columbia, MO each day?

Every day, the Indianapolis to Columbia, MO bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Indianapolis to Columbia, MO take?

The fastest bus from Indianapolis to Columbia, MO is offered by Greyhound US and takes 8h 35m. Bus tickets for this connection cost $40. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Indianapolis to Columbia, MO?

The earliest bus arriving in Columbia, MO from Indianapolis starts at 4:50 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Indianapolis to Columbia, MO?

The latest bus trip departing from Indianapolis for Columbia, MO starts at 7:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Indianapolis Columbia, MO route?

When traveling by bus from Indianapolis to Columbia, MO, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Indianapolis and Columbia, MO?

You can check all the direct connections between Indianapolis and Columbia, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Indianapolis to Columbia, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Indianapolis Columbia, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Indianapolis Columbia, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Indianapolis to Columbia, MO on your planned travel date.

How does CheckMyBus find the best bus deals from Indianapolis to Columbia, MO?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Indianapolis and Columbia, MO. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Indianapolis to Columbia, MO?

Prices and availability for 6 trips between Indianapolis and Columbia, MO change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Indianapolis to Columbia, MO

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Indianapolis and to Columbia, MO

Here’s an overview of the most popular bus routes to Indianapolis and to Columbia, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!