Bus Houston to San Diego - Compare all Companies

Compare all timetables for the bus from Houston to San Diego

Here is a selection of the cheapest bus trips from the schedule from Houston to San Diego from various bus operators like Greyhound US, FlixBus or Valley Transit for the next days.

today

$167

tomorrow

$153

Saturday

$156

Sunday

$151

Monday

Tuesday

$175

Wednesday

$164

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	40h 0m	8:15 AM	Houston	Harrisburg Blvd Station	10:15 PM	San Diego	Seaport Village	Economy	$167	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 8/27/2026 8:15:00 AM to Seaport Village, San Diego (USA) arriving at 8/28/2026 10:15:00 PM. 50 Economy ticket for $167 per person are available. Travel duration is 40h 0m
Greyhound US	40h 25m	2:00 AM	Houston	Harrisburg Blvd Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$168	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 8/27/2026 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/28/2026 4:25:00 PM. 50 Economy ticket for $168 per person are available. Travel duration is 40h 25m
Valley Transit	55h 10m	6:35 AM	Houston	SW Agencia Autobuses	11:45 AM	San Diego	Old Town Transit Center	Economy	$173	A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 8/27/2026 6:35:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/29/2026 11:45:00 AM. 50 Economy ticket for $173 per person are available. Travel duration is 55h 10m
Valley Transit	53h 50m	6:35 AM	Houston	SW Agencia Autobuses	10:25 AM	San Diego	Seaport Village	Economy	$174	A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 8/27/2026 6:35:00 AM to Seaport Village, San Diego (USA) arriving at 8/29/2026 10:25:00 AM. 50 Economy ticket for $174 per person are available. Travel duration is 53h 50m
FlixBus	47h 20m	2:25 PM	Houston	Downtown Houston	11:45 AM	San Diego	Old Town Transit Center	Economy	$174	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 8/27/2026 2:25:00 PM to Old Town Transit Center, San Diego (USA) arriving at 8/29/2026 11:45:00 AM. 50 Economy ticket for $174 per person are available. Travel duration is 47h 20m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	40h 25m	2:00 AM	Houston	Harrisburg Blvd Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$153	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 8/28/2026 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/29/2026 4:25:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 40h 25m
Greyhound US	39h 55m	2:00 AM	Houston	Harrisburg Blvd Station	3:55 PM	San Diego	La Jolla Village	Economy	$157	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 8/28/2026 2:00:00 AM to La Jolla Village, San Diego (USA) arriving at 8/29/2026 3:55:00 PM. 50 Economy ticket for $157 per person are available. Travel duration is 39h 55m
FlixBus	52h 40m	7:35 PM	Houston	Downtown Houston	10:15 PM	San Diego	Seaport Village	Economy	$162	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 8/28/2026 7:35:00 PM to Seaport Village, San Diego (USA) arriving at 8/30/2026 10:15:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 52h 40m
FlixBus	48h 10m	7:35 PM	Houston	Downtown Houston	5:45 PM	San Diego	Old Town Transit Center	Economy	$163	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 8/28/2026 7:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 8/30/2026 5:45:00 PM. 50 Economy ticket for $163 per person are available. Travel duration is 48h 10m
Valley Transit	53h 30m	6:35 AM	Houston	SW Agencia Autobuses	10:05 AM	San Diego	Old Town Transit Center	Economy	$167	A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 8/28/2026 6:35:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/30/2026 10:05:00 AM. 50 Economy ticket for $167 per person are available. Travel duration is 53h 30m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	40h 25m	2:00 AM	Houston	Harrisburg Blvd Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$156	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 8/29/2026 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/30/2026 4:25:00 PM. 50 Economy ticket for $156 per person are available. Travel duration is 40h 25m
Greyhound US	42h 20m	2:00 AM	Houston	Harrisburg Blvd Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$157	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 8/29/2026 2:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 8/30/2026 6:20:00 PM. 50 Economy ticket for $157 per person are available. Travel duration is 42h 20m
FlixBus	43h 45m	6:00 PM	Houston	Downtown Houston	11:45 AM	San Diego	Old Town Transit Center	Economy	$161	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 8/29/2026 6:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 8/31/2026 11:45:00 AM. 50 Economy ticket for $161 per person are available. Travel duration is 43h 45m
FlixBus	48h 25m	6:00 PM	Houston	Downtown Houston	4:25 PM	San Diego	Old Town Transit Center	Economy	$161	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 8/29/2026 6:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 8/31/2026 4:25:00 PM. 50 Economy ticket for $161 per person are available. Travel duration is 48h 25m
Valley Transit	59h 50m	6:35 AM	Houston	SW Agencia Autobuses	4:25 PM	San Diego	Old Town Transit Center	Economy	$163	A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 8/29/2026 6:35:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/31/2026 4:25:00 PM. 50 Economy ticket for $163 per person are available. Travel duration is 59h 50m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	40h 0m	8:15 AM	Houston	Harrisburg Blvd Station	10:15 PM	San Diego	Seaport Village	Economy	$151	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 8/30/2026 8:15:00 AM to Seaport Village, San Diego (USA) arriving at 8/31/2026 10:15:00 PM. 50 Economy ticket for $151 per person are available. Travel duration is 40h 0m
Greyhound US	40h 25m	2:00 AM	Houston	Harrisburg Blvd Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$153	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 8/30/2026 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/31/2026 4:25:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 40h 25m
Valley Transit	55h 10m	6:35 AM	Houston	SW Agencia Autobuses	11:45 AM	San Diego	Old Town Transit Center	Economy	$162	A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 8/30/2026 6:35:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/1/2026 11:45:00 AM. 50 Economy ticket for $162 per person are available. Travel duration is 55h 10m
FlixBus	48h 25m	6:00 PM	Houston	Downtown Houston	4:25 PM	San Diego	Old Town Transit Center	Economy	$165	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 8/30/2026 6:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/1/2026 4:25:00 PM. 50 Economy ticket for $165 per person are available. Travel duration is 48h 25m
FlixBus	43h 45m	6:00 PM	Houston	Downtown Houston	11:45 AM	San Diego	Old Town Transit Center	Economy	$165	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 8/30/2026 6:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/1/2026 11:45:00 AM. 50 Economy ticket for $165 per person are available. Travel duration is 43h 45m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	40h 25m	2:00 AM	Houston	Harrisburg Blvd Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$175	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 9/1/2026 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/2/2026 4:25:00 PM. 50 Economy ticket for $175 per person are available. Travel duration is 40h 25m
Greyhound US	35h 30m	8:15 AM	Houston	Harrisburg Blvd Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$181	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 9/1/2026 8:15:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/2/2026 5:45:00 PM. 50 Economy ticket for $181 per person are available. Travel duration is 35h 30m
FlixBus	48h 25m	6:00 PM	Houston	Downtown Houston	4:25 PM	San Diego	Old Town Transit Center	Economy	$194	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 9/1/2026 6:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/3/2026 4:25:00 PM. 50 Economy ticket for $194 per person are available. Travel duration is 48h 25m
Valley Transit	61h 45m	6:35 AM	Houston	SW Agencia Autobuses	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$195	A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 9/1/2026 6:35:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 9/3/2026 6:20:00 PM. 50 Economy ticket for $195 per person are available. Travel duration is 61h 45m
FlixBus	50h 20m	6:00 PM	Houston	Downtown Houston	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$197	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 9/1/2026 6:00:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 9/3/2026 6:20:00 PM. 50 Economy ticket for $197 per person are available. Travel duration is 50h 20m

Did you know that if you travel from Houston to San Diego via El Centro, CA, you can save more than $37? You can find the corresponding connections below.
- Greyhound US
  
  35h 30m
  
  0
  
  8:15 AM
  
  Houston
  Harrisburg Blvd Station
  
  3:05 PM
  
  El Centro, CA
  Bus Stop
  
  0
  
  Economy
  
  $117
  
  A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 8/31/2026 8:15:00 AM to Bus Stop, El Centro, CA (USA) arriving at 9/1/2026 3:05:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 32h 50m
- Greyhound US
  
  2h 30m
  
  0
  
  3:15 PM
  
  El Centro, CA
  Bus Stop
  
  5:45 PM
  
  San Diego
  Old Town Transit Center
  
  0
  
  Economy
  
  $21
  
  A Bus from Greyhound US goes from Bus Stop, El Centro, CA (USA) at 9/1/2026 3:15:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/1/2026 5:45:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 2h 30m
Travel time is 2h 0m longer, but you will save $37

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	40h 25m	2:00 AM	Houston	Harrisburg Blvd Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$164	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 9/2/2026 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/3/2026 4:25:00 PM. 50 Economy ticket for $164 per person are available. Travel duration is 40h 25m
Greyhound US	42h 20m	2:00 AM	Houston	Harrisburg Blvd Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$167	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 9/2/2026 2:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 9/3/2026 6:20:00 PM. 50 Economy ticket for $167 per person are available. Travel duration is 42h 20m
FlixBus	55h 15m	11:10 AM	Houston	Downtown Houston	4:25 PM	San Diego	Old Town Transit Center	Economy	$177	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 9/2/2026 11:10:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/4/2026 4:25:00 PM. 50 Economy ticket for $177 per person are available. Travel duration is 55h 15m
FlixBus	50h 35m	11:10 AM	Houston	Downtown Houston	11:45 AM	San Diego	Old Town Transit Center	Economy	$177	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 9/2/2026 11:10:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/4/2026 11:45:00 AM. 50 Economy ticket for $177 per person are available. Travel duration is 50h 35m
Valley Transit	59h 50m	6:35 AM	Houston	SW Agencia Autobuses	4:25 PM	San Diego	Old Town Transit Center	Economy	$180	A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 9/2/2026 6:35:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/4/2026 4:25:00 PM. 50 Economy ticket for $180 per person are available. Travel duration is 59h 50m

Did you know that if you travel from Houston to San Diego via El Centro, CA, you can save more than $26? You can find the corresponding connections below.
- Greyhound US
  
  35h 30m
  
  0
  
  8:15 AM
  
  Houston
  Harrisburg Blvd Station
  
  3:05 PM
  
  El Centro, CA
  Bus Stop
  
  0
  
  Economy
  
  $117
  
  A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 8/31/2026 8:15:00 AM to Bus Stop, El Centro, CA (USA) arriving at 9/1/2026 3:05:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 32h 50m
- Greyhound US
  
  2h 30m
  
  0
  
  3:15 PM
  
  El Centro, CA
  Bus Stop
  
  5:45 PM
  
  San Diego
  Old Town Transit Center
  
  0
  
  Economy
  
  $21
  
  A Bus from Greyhound US goes from Bus Stop, El Centro, CA (USA) at 9/1/2026 3:15:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/1/2026 5:45:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 2h 30m
Travel Time is 2h 55m shorter, and you will save $26

Best Price Offer: The price for the cheapest bus from Houston to San Diego is $140 on 8/24/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Houston and San Diego

See here how frequent the connections between Houston and San Diego are, during different times and days of the week.

Friday is the busiest day, with more than 48 daily buses from Houston to San Diego. Tuesday has instead the fewest connections, with only 15 daily coaches between Houston and San Diego.

The busiest time of the day is the Evening, with 80 buses from Houston to San Diego, while Afternoon sees the fewest connections between Houston and San Diego, with 14 offers.

Facts about the bus from Houston to San Diego

Compare all providers like Greyhound US, FlixBus and Valley Transit that travel 28 times every day by bus from Houston to San Diego in one click! Book your bus ticket from Houston to San Diego starting from $140!

Cheapest Bus	$140
Fastest Bus	33h 30m
Earliest Bus	2:00 AM
Latest Bus	6:55 PM
Daily Bus Routes	28 Ø
Distance	1,301.0 miles
Bus Companies	Greyhound US, FlixBus and Valley Transit

Cheapest bus connections from Houston to San Diego

Every day, 28 buses from 3 bus companies leave Houston for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 08/27/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 08/23

Monday 08/24

Tuesday 08/25

Wednesday 08/26

Thursday 08/27

$171

Friday 08/28

$157

Saturday 08/29

$160

Sunday 08/30

$151

Monday 08/31

Tuesday 09/01

$175

Wednesday 09/02

$164

Thursday 09/03

$156

Friday 09/04

$206

Saturday 09/05

$150

Sunday 09/06

$151

Monday 09/07

$163

Tuesday 09/08

$179

Wednesday 09/09

$163

Thursday 09/10

$158

Friday 09/11

$163

Saturday 09/12

$167

Sunday 09/13

$159

Monday 09/14

$141

Tuesday 09/15

$150

Wednesday 09/16

$160

Thursday 09/17

$165

Friday 09/18

Saturday 09/19

The cheapest time to travel from Houston to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from Houston to San Diego, for the next 30 days.

With a price starting from $150, Tuesday is the cheapest day for a bus from Houston to San Diego. Wednesday instead is the most expensive day with prices starting from $160.

Night is the cheapest day time for bus tickets from Houston to San Diego, with $141. Afternoon is the most expensive time of the day with prices starting from $174.

How to save money travelling from Houston to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Houston to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Houston to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Houston to San Diego are also emptier.

All bus stations and stops in Houston and San Diego

In the map below, you can see where to find all bus stations in Houston and San Diego.

Downtown Houston

Gray St 605

Harrisburg Blvd Station

Harrisburg Blvd 7000

Main Street

Main St 2121

Chase Bank

Milam Street 212

Uptown/Upper Kirby

Southwest Fwy 2525

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Santa Fe Depot

Kettner Blvd 1050

Seaport Village

W Harbor Dr 789

Downtown

Service and Comfort on the bus from Houston to San Diego

Want to know which seat classes are available on the buses from Houston to San Diego? Or which bus companies serve the route Houston to San Diego? Below you will find answers to your questions.

FAQs about the Houston to San Diego bus

How much does a Houston San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $140 and takes 38h 0m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Houston to San Diego?

This route is offered by 3 companies with a range of ticket prices between $140 and $213. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Houston to San Diego each day?

Every day, the Houston to San Diego bus route is served by approximately 28 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Houston to San Diego take?

The fastest bus from Houston to San Diego is offered by Greyhound US and takes 33h 30m. Bus tickets for this connection cost $173. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Houston to San Diego?

The earliest bus arriving in San Diego from Houston starts at 2:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Houston to San Diego?

The latest bus trip departing from Houston for San Diego starts at 6:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Houston San Diego route?

When traveling by bus from Houston to San Diego, passengers can travel with Greyhound US, FlixBus and Valley Transit. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Houston and San Diego?

You can check all the direct connections between Houston and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US, FlixBus and Valley Transit.

What can I take with me on the Houston to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Houston San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Houston San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Houston to San Diego on your planned travel date.

How does CheckMyBus find the best bus deals from Houston to San Diego?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 28 daily trips between Houston and San Diego. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Houston to San Diego?

Prices and availability for 28 trips between Houston and San Diego change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Houston to San Diego

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Houston and to San Diego

Here’s an overview of the most popular bus routes to Houston and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!