Which bus from Mexico City to San Diego is the cheapest?

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Compare all timetables for the bus from Mexico City to San Diego

Here is a selection of the cheapest bus trips from the schedule from Mexico City to San Diego from various bus operators like Flix Mexico for the next days.

today
$213
tomorrow
$210
Friday
$220
Saturday
$212
Sunday
$217
Monday
$215
Tuesday
$214

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Flix Mexico 73h 25m 10:20 PM Mexico City San Pedro Santa Clara Bus Stop 10:45 PM San Diego San Ysidro Transit Center  Economy $213
Flix Mexico 73h 0m 10:45 PM Mexico City Fórum Buenavista 10:45 PM San Diego San Ysidro Transit Center  Economy $213
Flix Mexico 69h 20m 10:00 PM Mexico City San Pedro Santa Clara Bus Stop 6:20 PM San Diego San Ysidro Transit Center  Economy $215
Flix Mexico 68h 55m 10:25 PM Mexico City Fórum Buenavista 6:20 PM San Diego San Ysidro Transit Center  Economy $215
Flix Mexico 68h 25m 10:20 PM Mexico City San Pedro Santa Clara Bus Stop 5:45 PM San Diego Old Town Transit Center  Economy $223
  • Did you know that if you travel from Mexico City to San Diego via Tijuana, BC, you can save more than $85? You can find the corresponding connections below.
    • ACN Autobuses
      59h 20m
      0
      10:30 PM
      Mexico City
      Eje Central Bus Stop
      4:30 PM
      Tijuana, BC
      Buena Vista
      0
      ACN Autobuses
      Economy
      $124
      • Waiting Time 14h 40m
    • Greyhound US
      1h 40m
      0
      7:10 AM
      Tijuana, BC
      Central Bus Station
      8:50 AM
      San Diego
      San Ysidro Transit Center
      0
      Greyhound US
      Economy
      $4
    Travel Time is 8h 5m shorter, and you will save $85

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Flix Mexico 69h 20m 10:00 PM Mexico City San Pedro Santa Clara Bus Stop 6:20 PM San Diego San Ysidro Transit Center  Economy $210
Flix Mexico 68h 55m 10:25 PM Mexico City Fórum Buenavista 6:20 PM San Diego San Ysidro Transit Center  Economy $210
Flix Mexico 68h 45m 2:40 PM Mexico City San Pedro Santa Clara Bus Stop 10:25 AM San Diego Seaport Village  Economy $218
Flix Mexico 68h 0m 2:40 PM Mexico City San Pedro Santa Clara Bus Stop 9:40 AM San Diego La Jolla Village  Economy $218
Flix Mexico 68h 25m 2:40 PM Mexico City San Pedro Santa Clara Bus Stop 10:05 AM San Diego Old Town Transit Center  Economy $218
  • Did you know that if you travel from Mexico City to San Diego via Tijuana, BC, you can save more than $83? You can find the corresponding connections below.
    • ACN Autobuses
      45h 5m
      0
      10:30 PM
      Mexico City
      Eje Central Bus Stop
      4:30 PM
      Tijuana, BC
      Buena Vista
      0
      ACN Autobuses
      Economy
      $123
      • Waiting Time 0h 30m
    • Greyhound US
      1h 35m
      0
      5:00 PM
      Tijuana, BC
      Central Bus Station
      6:35 PM
      San Diego
      San Ysidro Transit Center
      0
      Greyhound US
      Economy
      $4
    Travel Time is 21h 55m shorter, and you will save $83

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Flix Mexico 67h 50m 10:20 PM Mexico City San Pedro Santa Clara Bus Stop 5:10 PM San Diego San Ysidro Transit Center  Economy $220
Flix Mexico 72h 55m 10:20 PM Mexico City San Pedro Santa Clara Bus Stop 10:15 PM San Diego Seaport Village  Economy $222
Flix Mexico 72h 30m 10:45 PM Mexico City Fórum Buenavista 10:15 PM San Diego Seaport Village  Economy $222
Flix Mexico 68h 25m 10:20 PM Mexico City San Pedro Santa Clara Bus Stop 5:45 PM San Diego Old Town Transit Center  Economy $223
Flix Mexico 68h 0m 10:45 PM Mexico City Fórum Buenavista 5:45 PM San Diego Old Town Transit Center  Economy $223
  • Did you know that if you travel from Mexico City to San Diego via Tijuana, BC, you can save more than $93? You can find the corresponding connections below.
    • ACN Autobuses
      45h 5m
      0
      10:30 PM
      Mexico City
      Eje Central Bus Stop
      4:30 PM
      Tijuana, BC
      Buena Vista
      0
      ACN Autobuses
      Economy
      $123
      • Waiting Time 0h 30m
    • Greyhound US
      1h 35m
      0
      5:00 PM
      Tijuana, BC
      Central Bus Station
      6:35 PM
      San Diego
      San Ysidro Transit Center
      0
      Greyhound US
      Economy
      $4
    Travel Time is 21h 45m shorter, and you will save $93

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Flix Mexico 72h 30m 10:45 PM Mexico City Fórum Buenavista 10:15 PM San Diego Seaport Village  Economy $212
Flix Mexico 72h 0m 10:45 PM Mexico City Fórum Buenavista 9:45 PM San Diego La Jolla Village  Economy $213
Flix Mexico 68h 0m 10:45 PM Mexico City Fórum Buenavista 5:45 PM San Diego Old Town Transit Center  Economy $214
Flix Mexico 73h 0m 10:45 PM Mexico City Fórum Buenavista 10:45 PM San Diego San Ysidro Transit Center  Economy $221
Flix Mexico 69h 40m 3:05 PM Mexico City Fórum Buenavista 11:45 AM San Diego Old Town Transit Center  Economy $231
  • Did you know that if you travel from Mexico City to San Diego via Tijuana, BC, you can save more than $86? You can find the corresponding connections below.
    • ACN Autobuses
      59h 20m
      0
      10:30 PM
      Mexico City
      Eje Central Bus Stop
      4:30 PM
      Tijuana, BC
      Buena Vista
      0
      ACN Autobuses
      Economy
      $122
      • Waiting Time 14h 40m
    • Greyhound US
      1h 40m
      0
      7:10 AM
      Tijuana, BC
      Central Bus Station
      8:50 AM
      San Diego
      San Ysidro Transit Center
      0
      Greyhound US
      Economy
      $4
    Travel Time is 7h 40m shorter, and you will save $86

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Flix Mexico 68h 25m 10:20 PM Mexico City San Pedro Santa Clara Bus Stop 5:45 PM San Diego Old Town Transit Center  Economy $217
Flix Mexico 68h 0m 10:45 PM Mexico City Fórum Buenavista 5:45 PM San Diego Old Town Transit Center  Economy $217
Flix Mexico 72h 25m 10:20 PM Mexico City San Pedro Santa Clara Bus Stop 9:45 PM San Diego La Jolla Village  Economy $218
Flix Mexico 72h 0m 10:45 PM Mexico City Fórum Buenavista 9:45 PM San Diego La Jolla Village  Economy $218
Flix Mexico 72h 55m 10:20 PM Mexico City San Pedro Santa Clara Bus Stop 10:15 PM San Diego Seaport Village  Economy $218
  • Did you know that if you travel from Mexico City to San Diego via Tijuana, BC, you can save more than $91? You can find the corresponding connections below.
    • ACN Autobuses
      59h 20m
      0
      10:30 PM
      Mexico City
      Eje Central Bus Stop
      4:30 PM
      Tijuana, BC
      Buena Vista
      0
      ACN Autobuses
      Economy
      $122
      • Waiting Time 14h 40m
    • Greyhound US
      1h 40m
      0
      7:10 AM
      Tijuana, BC
      Central Bus Station
      8:50 AM
      San Diego
      San Ysidro Transit Center
      0
      Greyhound US
      Economy
      $4
    Travel Time is 7h 40m shorter, and you will save $91

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Flix Mexico 69h 20m 10:00 PM Mexico City San Pedro Santa Clara Bus Stop 6:20 PM San Diego San Ysidro Transit Center  Economy $215
Flix Mexico 68h 55m 10:25 PM Mexico City Fórum Buenavista 6:20 PM San Diego San Ysidro Transit Center  Economy $215
Flix Mexico 68h 25m 10:20 PM Mexico City San Pedro Santa Clara Bus Stop 5:45 PM San Diego Old Town Transit Center  Economy $216
Flix Mexico 72h 25m 10:20 PM Mexico City San Pedro Santa Clara Bus Stop 9:45 PM San Diego La Jolla Village  Economy $216
Flix Mexico 68h 0m 10:45 PM Mexico City Fórum Buenavista 5:45 PM San Diego Old Town Transit Center  Economy $216
  • Did you know that if you travel from Mexico City to San Diego via Tijuana, BC, you can save more than $90? You can find the corresponding connections below.
    • ACN Autobuses
      45h 5m
      0
      10:30 PM
      Mexico City
      Eje Central Bus Stop
      4:30 PM
      Tijuana, BC
      Buena Vista
      0
      ACN Autobuses
      Economy
      $121
      • Waiting Time 0h 30m
    • Greyhound US
      1h 35m
      0
      5:00 PM
      Tijuana, BC
      Central Bus Station
      6:35 PM
      San Diego
      San Ysidro Transit Center
      0
      Greyhound US
      Economy
      $4
    Travel Time is 21h 55m shorter, and you will save $90

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Flix Mexico 73h 15m 10:00 PM Mexico City San Pedro Santa Clara Bus Stop 10:15 PM San Diego Seaport Village  Economy $214
Flix Mexico 72h 50m 10:25 PM Mexico City Fórum Buenavista 10:15 PM San Diego Seaport Village  Economy $214
Flix Mexico 68h 45m 10:00 PM Mexico City San Pedro Santa Clara Bus Stop 5:45 PM San Diego Old Town Transit Center  Economy $216
Flix Mexico 68h 20m 10:25 PM Mexico City Fórum Buenavista 5:45 PM San Diego Old Town Transit Center  Economy $216
Flix Mexico 73h 10m 11:35 AM Mexico City San Pedro Santa Clara Bus Stop 11:45 AM San Diego Old Town Transit Center  Economy $234
  • Did you know that if you travel from Mexico City to San Diego via Tijuana, BC, you can save more than $89? You can find the corresponding connections below.
    • ACN Autobuses
      45h 5m
      0
      10:30 PM
      Mexico City
      Eje Central Bus Stop
      4:30 PM
      Tijuana, BC
      Buena Vista
      0
      ACN Autobuses
      Economy
      $121
      • Waiting Time 0h 30m
    • Greyhound US
      1h 35m
      0
      5:00 PM
      Tijuana, BC
      Central Bus Station
      6:35 PM
      San Diego
      San Ysidro Transit Center
      0
      Greyhound US
      Economy
      $4
    Travel Time is 22h 15m shorter, and you will save $89

Best Price Offer: The price for the cheapest bus from Mexico City to San Diego is $210 on 11/9/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Mexico City and San Diego

See here how frequent the connections between Mexico City and San Diego are, during different times and days of the week.
Thursday is the busiest day, with more than 30 daily buses from Mexico City to San Diego. Tuesday has instead the fewest connections, with only 10 daily coaches between Mexico City and San Diego.
The busiest time of the day is the Evening, with 70 buses from Mexico City to San Diego, while Morning sees the fewest connections between Mexico City and San Diego, with 12 offers.

Facts about the bus from Mexico City to San Diego

Compare all providers like Flix Mexico that travel 19 times every day by bus from Mexico City to San Diego in one click! Book your bus ticket from Mexico City to San Diego starting from $210!

Cheapest Bus $210
Fastest Bus 66h 35m
Earliest Bus 10:35 AM
Latest Bus 10:25 PM
Daily Bus Routes 19 Ø
Distance 1,443.3 miles
Bus Companies Flix Mexico

Cheapest bus connections from Mexico City to San Diego

Every day, 19 buses from 1 bus companies leave Mexico City for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/21/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 10/18
Monday 10/19
Tuesday 10/20
Wednesday 10/21
$213
Thursday 10/22
$210
Friday 10/23
$235
Saturday 10/24
$221
Sunday 10/25
$226
Monday 10/26
$215
Tuesday 10/27
$237
Wednesday 10/28
$215
Thursday 10/29
$224
Friday 10/30
$253
Saturday 10/31
$238
Sunday 11/01
$211
Monday 11/02
$214
Tuesday 11/03
$225
Wednesday 11/04
$212
Thursday 11/05
$236
Friday 11/06
$221
Saturday 11/07
$221
Sunday 11/08
$214
Monday 11/09
$210
Tuesday 11/10
$213
Wednesday 11/11
$211
Thursday 11/12
$212
Friday 11/13
$211
Saturday 11/14

The cheapest time to travel from Mexico City to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from Mexico City to San Diego, for the next 30 days.
With a price starting from $210, Monday is the cheapest day for a bus from Mexico City to San Diego. Tuesday instead is the most expensive day with prices starting from $213.
Evening is the cheapest day time for bus tickets from Mexico City to San Diego, with $210. Morning is the most expensive time of the day with prices starting from $227.

How to save money travelling from Mexico City to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mexico City to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mexico City to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mexico City to San Diego are also emptier.

Beloved bus companies from Mexico City to San Diego

These are the most booked bus companies between Mexico City to San Diego from our users.

Flix Mexico from Mexico City to San Diego

Flix Mexico

Here you will find the key facts about the Flix Mexico bus route Mexico City to San Diego:

Cheapest Price $210
Fastest Bus 66h 35m
Earliest Bus 10:35 AM
Last Bus 10:25 PM
Daily Connections 19 Ø
Found on 10/20/2026

All bus stations and stops in Mexico City and San Diego

In the map below, you can see where to find all bus stations in Mexico City and San Diego.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Mexico City to San Diego? Compare all modes of transports from Mexico City to San Diego.

Service and Comfort on the bus from Mexico City to San Diego

Want to know which seat classes are available on the buses from Mexico City to San Diego? Or which bus companies serve the route Mexico City to San Diego? Below you will find answers to your questions.

FAQs about the Mexico City to San Diego bus

How much does a Mexico City San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $210 and takes 68h 20m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Mexico City to San Diego?

This route is offered by 1 companies with a range of ticket prices between $210 and $282. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Mexico City to San Diego each day?

Every day, the Mexico City to San Diego bus route is served by approximately 19 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mexico City to San Diego take?

The fastest bus from Mexico City to San Diego is offered by Flix Mexico and takes 66h 35m. Bus tickets for this connection cost $218. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mexico City to San Diego?

The earliest bus arriving in San Diego from Mexico City starts at 10:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mexico City to San Diego?

The latest bus trip departing from Mexico City for San Diego starts at 10:25 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mexico City San Diego route?

When traveling by bus from Mexico City to San Diego, passengers can travel with Flix Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mexico City and San Diego?

You can check all the direct connections between Mexico City and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Flix Mexico.

What can I take with me on the Mexico City to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mexico City San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mexico City San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mexico City to San Diego on your planned travel date.

How does CheckMyBus find the best bus deals from Mexico City to San Diego?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 19 daily trips between Mexico City and San Diego. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Mexico City to San Diego?

Prices and availability for 19 trips between Mexico City and San Diego change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Mexico City to San Diego

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mexico City and to San Diego

Here’s an overview of the most popular bus routes to Mexico City and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus to Mexico City from Acaponeta Bus to Mexico City from Acaponeta
Bus from Jiquilpan to Mexico City Bus from Jiquilpan to Mexico City
From Tonalá to Mexico City bus From Tonalá to Mexico City bus
Bus to Mexico City from San Cristóbal de las Casas Bus to Mexico City from San Cristóbal de las Casas
Hayward, CA to San Diego bus Hayward, CA to San Diego bus
Buses Lubbock, TX to San Diego Buses Lubbock, TX to San Diego
Buses from Gilroy, CA to San Diego Buses from Gilroy, CA to San Diego
Buses Downey, CA - San Diego Buses Downey, CA - San Diego
Popular Airport Shuttles to Mexico City and to San Diego
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