Bus Tupelo, MS to Houston: Compare prices and save money

Compare all timetables for the bus from Tupelo, MS to Houston

Here is a selection of the cheapest bus trips from the schedule from Tupelo, MS to Houston from various bus operators like Greyhound US for the next days.

today

$85

tomorrow

$82

Saturday

$76

Sunday

$86

Monday

Tuesday

$96

Wednesday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	17h 55m	5:35 AM	Tupelo, MS	Bus Stop	11:30 PM	Houston	Harrisburg Blvd Station	Economy	$85	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/27/2026 5:35:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 8/27/2026 11:30:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 17h 55m
Greyhound US	20h 15m	10:55 AM	Tupelo, MS	Bus Stop	7:10 AM	Houston	Harrisburg Blvd Station	Economy	$86	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/27/2026 10:55:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 8/28/2026 7:10:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 20h 15m
Greyhound US	19h 20m	9:45 PM	Tupelo, MS	Bus Stop	5:05 PM	Houston	Harrisburg Blvd Station	Economy	$86	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/27/2026 9:45:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 8/28/2026 5:05:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 19h 20m
Greyhound US	20h 20m	9:45 PM	Tupelo, MS	Bus Stop	6:05 PM	Houston	Downtown Houston	Economy	$86	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/27/2026 9:45:00 PM to Downtown Houston, Houston (USA) arriving at 8/28/2026 6:05:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 20h 20m
Greyhound US	27h 20m	10:55 AM	Tupelo, MS	Bus Stop	2:15 PM	Houston	Downtown Houston	Economy	$87	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/27/2026 10:55:00 AM to Downtown Houston, Houston (USA) arriving at 8/28/2026 2:15:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 27h 20m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	20h 15m	10:55 AM	Tupelo, MS	Bus Stop	7:10 AM	Houston	Harrisburg Blvd Station	Economy	$82	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/28/2026 10:55:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 8/29/2026 7:10:00 AM. 50 Economy ticket for $82 per person are available. Travel duration is 20h 15m
Greyhound US	19h 20m	9:45 PM	Tupelo, MS	Bus Stop	5:05 PM	Houston	Harrisburg Blvd Station	Economy	$82	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/28/2026 9:45:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 8/29/2026 5:05:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 19h 20m
Greyhound US	23h 35m	11:15 PM	Tupelo, MS	Bus Stop	10:50 PM	Houston	Harrisburg Blvd Station	Economy	$82	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/28/2026 11:15:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 8/29/2026 10:50:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 23h 35m
Greyhound US	20h 20m	9:45 PM	Tupelo, MS	Bus Stop	6:05 PM	Houston	Downtown Houston	Economy	$82	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/28/2026 9:45:00 PM to Downtown Houston, Houston (USA) arriving at 8/29/2026 6:05:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 20h 20m
Greyhound US	29h 50m	11:15 PM	Tupelo, MS	Bus Stop	5:05 AM	Houston	Downtown Houston	Economy	$83	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/28/2026 11:15:00 PM to Downtown Houston, Houston (USA) arriving at 8/30/2026 5:05:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 29h 50m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	17h 55m	5:35 AM	Tupelo, MS	Bus Stop	11:30 PM	Houston	Harrisburg Blvd Station	Economy	$76	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/29/2026 5:35:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 8/29/2026 11:30:00 PM. 50 Economy ticket for $76 per person are available. Travel duration is 17h 55m
Greyhound US	19h 20m	9:45 PM	Tupelo, MS	Bus Stop	5:05 PM	Houston	Harrisburg Blvd Station	Economy	$77	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/29/2026 9:45:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 8/30/2026 5:05:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 19h 20m
Greyhound US	25h 5m	10:55 AM	Tupelo, MS	Bus Stop	12:00 PM	Houston	Downtown Houston	Economy	$77	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/29/2026 10:55:00 AM to Downtown Houston, Houston (USA) arriving at 8/30/2026 12:00:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 25h 5m
Greyhound US	20h 20m	9:45 PM	Tupelo, MS	Bus Stop	6:05 PM	Houston	Downtown Houston	Economy	$77	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/29/2026 9:45:00 PM to Downtown Houston, Houston (USA) arriving at 8/30/2026 6:05:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 20h 20m
Greyhound US	29h 50m	11:15 PM	Tupelo, MS	Bus Stop	5:05 AM	Houston	Downtown Houston	Economy	$77	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/29/2026 11:15:00 PM to Downtown Houston, Houston (USA) arriving at 8/31/2026 5:05:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 29h 50m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	17h 55m	5:35 AM	Tupelo, MS	Bus Stop	11:30 PM	Houston	Harrisburg Blvd Station	Economy	$86	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/30/2026 5:35:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 8/30/2026 11:30:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 17h 55m
Greyhound US	19h 20m	9:45 PM	Tupelo, MS	Bus Stop	5:05 PM	Houston	Harrisburg Blvd Station	Economy	$86	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/30/2026 9:45:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 8/31/2026 5:05:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 19h 20m
Greyhound US	25h 5m	10:55 AM	Tupelo, MS	Bus Stop	12:00 PM	Houston	Downtown Houston	Economy	$86	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/30/2026 10:55:00 AM to Downtown Houston, Houston (USA) arriving at 8/31/2026 12:00:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 25h 5m
Greyhound US	20h 15m	10:55 AM	Tupelo, MS	Bus Stop	7:10 AM	Houston	Harrisburg Blvd Station	Economy	$87	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/30/2026 10:55:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 8/31/2026 7:10:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 20h 15m
Greyhound US	20h 20m	9:45 PM	Tupelo, MS	Bus Stop	6:05 PM	Houston	Downtown Houston	Economy	$87	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/30/2026 9:45:00 PM to Downtown Houston, Houston (USA) arriving at 8/31/2026 6:05:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 20h 20m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	20h 15m	10:55 AM	Tupelo, MS	Bus Stop	7:10 AM	Houston	Harrisburg Blvd Station	Economy	$96	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 9/1/2026 10:55:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 9/2/2026 7:10:00 AM. 50 Economy ticket for $96 per person are available. Travel duration is 20h 15m
Greyhound US	19h 20m	9:45 PM	Tupelo, MS	Bus Stop	5:05 PM	Houston	Harrisburg Blvd Station	Economy	$96	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 9/1/2026 9:45:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 9/2/2026 5:05:00 PM. 50 Economy ticket for $96 per person are available. Travel duration is 19h 20m
Greyhound US	23h 35m	11:15 PM	Tupelo, MS	Bus Stop	10:50 PM	Houston	Harrisburg Blvd Station	Economy	$96	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 9/1/2026 11:15:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 9/2/2026 10:50:00 PM. 50 Economy ticket for $96 per person are available. Travel duration is 23h 35m
Greyhound US	23h 30m	5:35 AM	Tupelo, MS	Bus Stop	5:05 AM	Houston	Downtown Houston	Economy	$97	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 9/1/2026 5:35:00 AM to Downtown Houston, Houston (USA) arriving at 9/2/2026 5:05:00 AM. 50 Economy ticket for $97 per person are available. Travel duration is 23h 30m
Greyhound US	25h 5m	10:55 AM	Tupelo, MS	Bus Stop	12:00 PM	Houston	Downtown Houston	Economy	$97	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 9/1/2026 10:55:00 AM to Downtown Houston, Houston (USA) arriving at 9/2/2026 12:00:00 PM. 50 Economy ticket for $97 per person are available. Travel duration is 25h 5m

Best Price Offer: The price for the cheapest bus from Tupelo, MS to Houston is $74 on 9/14/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Tupelo, MS and Houston

See here how frequent the connections between Tupelo, MS and Houston are, during different times and days of the week.

Sunday is the busiest day, with more than 16 daily buses from Tupelo, MS to Houston. Thursday has instead the fewest connections, with only 8 daily coaches between Tupelo, MS and Houston.

The busiest time of the day is the Evening, with 28 buses from Tupelo, MS to Houston, while Morning sees the fewest connections between Tupelo, MS and Houston, with 16 offers.

Facts about the bus from Tupelo, MS to Houston

Compare all providers like Greyhound US that travel 12 times every day by bus from Tupelo, MS to Houston in one click! Book your bus ticket from Tupelo, MS to Houston starting from $74!

Cheapest Bus	$74
Fastest Bus	17h 55m
Earliest Bus	5:35 AM
Latest Bus	11:15 PM
Daily Bus Routes	12 Ø
Distance	499.6 miles
Bus Companies	Greyhound US

Cheapest bus connections from Tupelo, MS to Houston

Every day, 12 buses from 1 bus companies leave Tupelo, MS for Houston: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 08/27/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 08/23

Monday 08/24

Tuesday 08/25

Wednesday 08/26

Thursday 08/27

$85

Friday 08/28

$82

Saturday 08/29

$76

Sunday 08/30

$86

Monday 08/31

Tuesday 09/01

$100

Wednesday 09/02

Thursday 09/03

$108

Friday 09/04

$98

Saturday 09/05

Sunday 09/06

$94

Monday 09/07

$115

Tuesday 09/08

$90

Wednesday 09/09

$77

Thursday 09/10

$79

Friday 09/11

$77

Saturday 09/12

$78

Sunday 09/13

Monday 09/14

$74

Tuesday 09/15

$81

Wednesday 09/16

$82

Thursday 09/17

$82

Friday 09/18

$80

Saturday 09/19

The cheapest time to travel from Tupelo, MS to Houston

See here on which day and which time of the day you can find the cheapest bus ticket from Tupelo, MS to Houston, for the next 30 days.

With a price starting from $74, Saturday is the cheapest day for a bus from Tupelo, MS to Houston. Tuesday instead is the most expensive day with prices starting from $79.

Night is the cheapest day time for bus tickets from Tupelo, MS to Houston, with $74. Morning is the most expensive time of the day with prices starting from $77.

How to save money travelling from Tupelo, MS to Houston

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Tupelo, MS to Houston in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Tupelo, MS to Houston, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Tupelo, MS to Houston are also emptier.

Beloved bus companies from Tupelo, MS to Houston

These are the most booked bus companies between Tupelo, MS to Houston from our users.

Greyhound US from Tupelo, MS to Houston

Here you will find the key facts about the Greyhound US bus route Tupelo, MS to Houston:

Cheapest Price	$76
Fastest Bus	17h 55m
Earliest Bus	5:35 AM
Last Bus	11:15 PM
Daily Connections	12 Ø
Found on	8/2/2026

All bus stations and stops in Tupelo, MS and Houston

In the map below, you can see where to find all bus stations in Tupelo, MS and Houston.

Bus Stop

S Eason Blvd 2831

Downtown Houston

Gray St 605

Harrisburg Blvd Station

Harrisburg Blvd 7000

Main Street

Main St 2121

Chase Bank

Milam Street 212

Uptown/Upper Kirby

Southwest Fwy 2525

Service and Comfort on the bus from Tupelo, MS to Houston

Want to know which seat classes are available on the buses from Tupelo, MS to Houston? Or which bus companies serve the route Tupelo, MS to Houston? Below you will find answers to your questions.

FAQs about the Tupelo, MS to Houston bus

How much does a Tupelo, MS Houston bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $74 and takes 17h 55m to reach Houston. Compare offers to save money!

How much could I save by comparing buses from Tupelo, MS to Houston?

This route is offered by 1 companies with a range of ticket prices between $74 and $112. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Houston.

On average, how many connections are available from Tupelo, MS to Houston each day?

Every day, the Tupelo, MS to Houston bus route is served by approximately 12 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Tupelo, MS to Houston take?

The fastest bus from Tupelo, MS to Houston is offered by Greyhound US and takes 17h 55m. Bus tickets for this connection cost $85. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Tupelo, MS to Houston?

The earliest bus arriving in Houston from Tupelo, MS starts at 5:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Tupelo, MS to Houston?

The latest bus trip departing from Tupelo, MS for Houston starts at 11:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Tupelo, MS Houston route?

When traveling by bus from Tupelo, MS to Houston, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Tupelo, MS and Houston?

You can check all the direct connections between Tupelo, MS and Houston by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Tupelo, MS to Houston bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Tupelo, MS Houston bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Tupelo, MS Houston bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Tupelo, MS to Houston on your planned travel date.

How does CheckMyBus find the best bus deals from Tupelo, MS to Houston?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 12 daily trips between Tupelo, MS and Houston. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Tupelo, MS to Houston?

Prices and availability for 12 trips between Tupelo, MS and Houston change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Tupelo, MS to Houston

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Tupelo, MS and to Houston

Here’s an overview of the most popular bus routes to Tupelo, MS and to Houston. Simply click on the connection of your choice, and you will find all the details about your bus route!