Bus Tupelo, MS to Cincinnati: Compare prices and save money

Compare all timetables for the bus from Tupelo, MS to Cincinnati

Here is a selection of the cheapest bus trips from the schedule from Tupelo, MS to Cincinnati from various bus operators like Greyhound US for the next days.

today

tomorrow

$74

Thursday

$75

Friday

$81

Saturday

$83

Sunday

$90

Monday

$78

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	15h 45m	10:55 AM	Tupelo, MS	Bus Stop	3:40 AM	Cincinnati	Greyhound Bus Station		Economy	$74	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/26/2026 10:55:00 AM to Greyhound Bus Station, Cincinnati (USA) arriving at 8/27/2026 3:40:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 15h 45m

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	15h 45m	10:55 AM	Tupelo, MS	Bus Stop	3:40 AM	Cincinnati	Greyhound Bus Station		Economy	$75	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/27/2026 10:55:00 AM to Greyhound Bus Station, Cincinnati (USA) arriving at 8/28/2026 3:40:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 15h 45m
	Greyhound US	18h 40m	9:45 PM	Tupelo, MS	Bus Stop	5:25 PM	Cincinnati	Greyhound Bus Station		Economy	$85	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/27/2026 9:45:00 PM to Greyhound Bus Station, Cincinnati (USA) arriving at 8/28/2026 5:25:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 18h 40m

Cheapest bus trips Friday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	18h 40m	9:45 PM	Tupelo, MS	Bus Stop	5:25 PM	Cincinnati	E Galbraith Rd		Economy	$81	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/28/2026 9:45:00 PM to E Galbraith Rd, Cincinnati (USA) arriving at 8/29/2026 5:25:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 18h 40m
	Greyhound US	15h 45m	10:55 AM	Tupelo, MS	Bus Stop	3:40 AM	Cincinnati	E Galbraith Rd		Economy	$88	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/28/2026 10:55:00 AM to E Galbraith Rd, Cincinnati (USA) arriving at 8/29/2026 3:40:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 15h 45m

Cheapest bus trips Saturday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	18h 40m	9:45 PM	Tupelo, MS	Bus Stop	5:25 PM	Cincinnati	E Galbraith Rd		Economy	$83	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/29/2026 9:45:00 PM to E Galbraith Rd, Cincinnati (USA) arriving at 8/30/2026 5:25:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 18h 40m
	Greyhound US	15h 45m	10:55 AM	Tupelo, MS	Bus Stop	3:40 AM	Cincinnati	E Galbraith Rd		Economy	$84	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/29/2026 10:55:00 AM to E Galbraith Rd, Cincinnati (USA) arriving at 8/30/2026 3:40:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 15h 45m

Cheapest bus trips Sunday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	18h 40m	9:45 PM	Tupelo, MS	Bus Stop	5:25 PM	Cincinnati	Greyhound Bus Station		Economy	$90	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/30/2026 9:45:00 PM to Greyhound Bus Station, Cincinnati (USA) arriving at 8/31/2026 5:25:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 18h 40m
	Greyhound US	15h 45m	10:55 AM	Tupelo, MS	Bus Stop	3:40 AM	Cincinnati	Greyhound Bus Station		Economy	$91	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/30/2026 10:55:00 AM to Greyhound Bus Station, Cincinnati (USA) arriving at 8/31/2026 3:40:00 AM. 50 Economy ticket for $91 per person are available. Travel duration is 15h 45m

Did you know that if you travel from Tupelo, MS to Cincinnati via Nashville, you can save more than $12? You can find the corresponding connections below.
- Greyhound US
  
  18h 40m
  
  0
  
  9:45 PM
  
  Tupelo, MS
  Bus Stop
  
  4:25 AM
  
  Nashville
  5th Ave South Station
  
  0
  
  Economy
  
  $44
  
  A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/26/2026 9:45:00 PM to 5th Ave South Station, Nashville (USA) arriving at 8/27/2026 4:25:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 6h 40m
- Greyhound US
  
  6h 35m
  
  0
  
  9:50 AM
  
  Nashville
  5th Ave South Station
  
  5:25 PM
  
  Cincinnati
  E Galbraith Rd
  
  0
  
  Economy
  
  $34
  
  A Bus from Greyhound US goes from 5th Ave South Station, Nashville (USA) at 8/27/2026 9:50:00 AM to E Galbraith Rd, Cincinnati (USA) arriving at 8/27/2026 5:25:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 6h 35m
Travel time is 1h 55m longer, but you will save $12

Cheapest bus trips Monday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	15h 45m	10:55 AM	Tupelo, MS	Bus Stop	3:40 AM	Cincinnati	Greyhound Bus Station		Economy	$78	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/31/2026 10:55:00 AM to Greyhound Bus Station, Cincinnati (USA) arriving at 9/1/2026 3:40:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 15h 45m
	Greyhound US	18h 40m	9:45 PM	Tupelo, MS	Bus Stop	5:25 PM	Cincinnati	Greyhound Bus Station		Economy	$79	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 8/31/2026 9:45:00 PM to Greyhound Bus Station, Cincinnati (USA) arriving at 9/1/2026 5:25:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 18h 40m

Best Price Offer: The price for the cheapest bus from Tupelo, MS to Cincinnati is $69 on 9/17/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Tupelo, MS and Cincinnati

See here how frequent the connections between Tupelo, MS and Cincinnati are, during different times and days of the week.

Friday is the busiest day, with more than 4 daily buses from Tupelo, MS to Cincinnati. Wednesday has instead the fewest connections, with only 1 daily coaches between Tupelo, MS and Cincinnati.

The busiest time of the day is the Morning, with 8 buses from Tupelo, MS to Cincinnati, while Evening sees the fewest connections between Tupelo, MS and Cincinnati, with 7 offers.

Facts about the bus from Tupelo, MS to Cincinnati

Compare all providers like Greyhound US that travel 2 times every day by bus from Tupelo, MS to Cincinnati in one click! Book your bus ticket from Tupelo, MS to Cincinnati starting from $69!

Cheapest Bus	$69
Fastest Bus	16h 45m
Earliest Bus	10:55 AM
Latest Bus	9:45 PM
Daily Bus Routes	2 Ø
Distance	406.9 miles
Bus Companies	Greyhound US

Cheapest bus connections from Tupelo, MS to Cincinnati

Every day, 2 buses from 1 bus companies leave Tupelo, MS for Cincinnati: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 08/25/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 08/23

Monday 08/24

Tuesday 08/25

Wednesday 08/26

$74

Thursday 08/27

$75

Friday 08/28

$85

Saturday 08/29

$87

Sunday 08/30

$90

Monday 08/31

$78

Tuesday 09/01

$99

Wednesday 09/02

Thursday 09/03

Friday 09/04

$82

Saturday 09/05

$86

Sunday 09/06

$86

Monday 09/07

Tuesday 09/08

Wednesday 09/09

Thursday 09/10

$70

Friday 09/11

Saturday 09/12

$79

Sunday 09/13

Monday 09/14

$78

Tuesday 09/15

$76

Wednesday 09/16

Thursday 09/17

$69

Friday 09/18

$74

Saturday 09/19

The cheapest time to travel from Tupelo, MS to Cincinnati

See here on which day and which time of the day you can find the cheapest bus ticket from Tupelo, MS to Cincinnati, for the next 30 days.

With a price starting from $69, Thursday is the cheapest day for a bus from Tupelo, MS to Cincinnati. Saturday instead is the most expensive day with prices starting from $79.

Morning is the cheapest day time for bus tickets from Tupelo, MS to Cincinnati, with $74. Evening is the most expensive time of the day with prices starting from $79.

How to save money travelling from Tupelo, MS to Cincinnati

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Tupelo, MS to Cincinnati in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Tupelo, MS to Cincinnati, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Tupelo, MS to Cincinnati are also emptier.

All bus stations and stops in Tupelo, MS and Cincinnati

In the map below, you can see where to find all bus stations in Tupelo, MS and Cincinnati.

Bus Stop

S Eason Blvd 2831

University of Cincinnati

Commons Way 2815

Greyhound Bus Station

Gilbert Ave 1005

E Galbraith Rd

Downtown

E Court St 419

Hughes STEM High School

2515 Clifton Ave

Service and Comfort on the bus from Tupelo, MS to Cincinnati

Want to know which seat classes are available on the buses from Tupelo, MS to Cincinnati? Or which bus companies serve the route Tupelo, MS to Cincinnati? Below you will find answers to your questions.

FAQs about the Tupelo, MS to Cincinnati bus

How much does a Tupelo, MS Cincinnati bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $69 and takes 16h 45m to reach Cincinnati. Compare offers to save money!

How much could I save by comparing buses from Tupelo, MS to Cincinnati?

This route is offered by 1 companies with a range of ticket prices between $69 and $92. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Cincinnati.

On average, how many connections are available from Tupelo, MS to Cincinnati each day?

Every day, the Tupelo, MS to Cincinnati bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Tupelo, MS to Cincinnati take?

The fastest bus from Tupelo, MS to Cincinnati is offered by Greyhound US and takes 16h 45m. Bus tickets for this connection cost $74. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Tupelo, MS to Cincinnati?

The earliest bus arriving in Cincinnati from Tupelo, MS starts at 10:55 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Tupelo, MS to Cincinnati?

The latest bus trip departing from Tupelo, MS for Cincinnati starts at 9:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Tupelo, MS Cincinnati route?

When traveling by bus from Tupelo, MS to Cincinnati, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Tupelo, MS and Cincinnati?

You can check all the direct connections between Tupelo, MS and Cincinnati by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Tupelo, MS to Cincinnati bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Tupelo, MS Cincinnati bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Tupelo, MS Cincinnati bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Tupelo, MS to Cincinnati on your planned travel date.

How does CheckMyBus find the best bus deals from Tupelo, MS to Cincinnati?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Tupelo, MS and Cincinnati. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Tupelo, MS to Cincinnati?

Prices and availability for 2 trips between Tupelo, MS and Cincinnati change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Tupelo, MS to Cincinnati

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Tupelo, MS and to Cincinnati

Here’s an overview of the most popular bus routes to Tupelo, MS and to Cincinnati. Simply click on the connection of your choice, and you will find all the details about your bus route!