Compare all timetables for the bus from Talca, ML to La Serena
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 12h 50m | 11:30 AM | Talca, ML | Ocho Sur/ Veintiuno y Medio Ote Bus Stop | 12:20 AM | La Serena | Central Bus Station | Economy | $20 |
A Bus from FlixBus goes from Ocho Sur/ Veintiuno y Medio Ote Bus Stop, Talca, ML (Chile) at 10/22/2026 11:30:00 AM to Central Bus Station, La Serena (Chile) arriving at 10/23/2026 12:20:00 AM. 50 Economy ticket for $20 per person are available. Travel duration is 12h 50m
|
||
| FlixBus | 11h 15m | 4:45 PM | Talca, ML | Ocho Sur/ Veintiuno y Medio Ote Bus Stop | 4:00 AM | La Serena | Central Bus Station | Economy | $25 |
A Bus from FlixBus goes from Ocho Sur/ Veintiuno y Medio Ote Bus Stop, Talca, ML (Chile) at 10/22/2026 4:45:00 PM to Central Bus Station, La Serena (Chile) arriving at 10/23/2026 4:00:00 AM. 50 Economy ticket for $25 per person are available. Travel duration is 11h 15m
|
||
| FlixBus | 13h 0m | 11:20 AM | Talca, ML | Cruce Varoli | 12:20 AM | La Serena | Central Bus Station | Economy | $26 |
A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 10/22/2026 11:20:00 AM to Central Bus Station, La Serena (Chile) arriving at 10/23/2026 12:20:00 AM. 50 Economy ticket for $26 per person are available. Travel duration is 13h 0m
|
||
| FlixBus | 11h 10m | 4:50 PM | Talca, ML | Cruce Varoli | 4:00 AM | La Serena | Central Bus Station | Economy | $31 |
A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 10/22/2026 4:50:00 PM to Central Bus Station, La Serena (Chile) arriving at 10/23/2026 4:00:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 11h 10m
|
-
-
FlixBus10h 46m011:30 AMTalca, MLCruce Varoli2:50 PMSantiago, RMTerminal San Borja0BusinessA Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 10/23/2026 11:30:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 10/23/2026 2:50:00 PM. 50 Business ticket for $6 per person are available. Travel duration is 3h 20m
-
Pluss Chile6h 20m03:56 PMSantiago, RMSur Bus Station10:16 PMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 10/23/2026 3:56:00 PM to Central Bus Station, La Serena (Chile) arriving at 10/23/2026 10:16:00 PM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 6h 20m
Waiting Time 1h 6m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 13h 0m | 11:20 AM | Talca, ML | Cruce Varoli | 12:20 AM | La Serena | Central Bus Station | Economy | $20 |
A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 10/23/2026 11:20:00 AM to Central Bus Station, La Serena (Chile) arriving at 10/24/2026 12:20:00 AM. 50 Economy ticket for $20 per person are available. Travel duration is 13h 0m
|
||
| FlixBus | 11h 40m | 10:20 AM | Talca, ML | Cruce Varoli | 10:00 PM | La Serena | Central Bus Station | Economy | $22 |
A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 10/23/2026 10:20:00 AM to Central Bus Station, La Serena (Chile) arriving at 10/23/2026 10:00:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 11h 40m
|
||
| FlixBus | 11h 10m | 4:50 PM | Talca, ML | Cruce Varoli | 4:00 AM | La Serena | Central Bus Station | Economy | $23 |
A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 10/23/2026 4:50:00 PM to Central Bus Station, La Serena (Chile) arriving at 10/24/2026 4:00:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 11h 10m
|
||
| Turbus | 10h 0m | 12:10 PM | Talca, ML | Central Bus Station | 10:10 PM | La Serena | Avda. Fco de Aguirre Station | Premium Economy | $38 |
A Bus from Turbus goes from Central Bus Station, Talca, ML (Chile) at 10/23/2026 12:10:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 10/23/2026 10:10:00 PM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 10h 0m
|
-
-
FlixBus10h 46m011:30 AMTalca, MLCruce Varoli2:50 PMSantiago, RMTerminal San Borja0BusinessA Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 10/23/2026 11:30:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 10/23/2026 2:50:00 PM. 50 Business ticket for $6 per person are available. Travel duration is 3h 20m
-
Pluss Chile6h 20m03:56 PMSantiago, RMSur Bus Station10:16 PMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 10/23/2026 3:56:00 PM to Central Bus Station, La Serena (Chile) arriving at 10/23/2026 10:16:00 PM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 6h 20m
Waiting Time 1h 6m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 12h 50m | 11:30 AM | Talca, ML | Cruce Varoli | 12:20 AM | La Serena | Central Bus Station | Economy | $20 |
A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 10/24/2026 11:30:00 AM to Central Bus Station, La Serena (Chile) arriving at 10/25/2026 12:20:00 AM. 50 Economy ticket for $20 per person are available. Travel duration is 12h 50m
|
||
| FlixBus | 11h 15m | 4:45 PM | Talca, ML | Cruce Varoli | 4:00 AM | La Serena | Central Bus Station | Economy | $23 |
A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 10/24/2026 4:45:00 PM to Central Bus Station, La Serena (Chile) arriving at 10/25/2026 4:00:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 11h 15m
|
||
| FlixBus | 13h 0m | 11:20 AM | Talca, ML | Ocho Sur/ Veintiuno y Medio Ote Bus Stop | 12:20 AM | La Serena | Central Bus Station | Economy | $28 |
A Bus from FlixBus goes from Ocho Sur/ Veintiuno y Medio Ote Bus Stop, Talca, ML (Chile) at 10/24/2026 11:20:00 AM to Central Bus Station, La Serena (Chile) arriving at 10/25/2026 12:20:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 13h 0m
|
||
| Turbus | 10h 0m | 12:10 PM | Talca, ML | Central Bus Station | 10:10 PM | La Serena | Avda. Fco de Aguirre Station | Premium Economy | $30 |
A Bus from Turbus goes from Central Bus Station, Talca, ML (Chile) at 10/24/2026 12:10:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 10/24/2026 10:10:00 PM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 10h 0m
|
-
-
FlixBus10h 46m011:30 AMTalca, MLCruce Varoli2:50 PMSantiago, RMTerminal San Borja0BusinessA Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 10/23/2026 11:30:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 10/23/2026 2:50:00 PM. 50 Business ticket for $6 per person are available. Travel duration is 3h 20m
-
Pluss Chile6h 20m03:56 PMSantiago, RMSur Bus Station10:16 PMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 10/23/2026 3:56:00 PM to Central Bus Station, La Serena (Chile) arriving at 10/23/2026 10:16:00 PM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 6h 20m
Waiting Time 1h 6m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 10h 35m | 10:20 AM | Talca, ML | Cruce Varoli | 8:55 PM | La Serena | Central Bus Station | Economy | $32 |
A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 10/25/2026 10:20:00 AM to Central Bus Station, La Serena (Chile) arriving at 10/25/2026 8:55:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 10h 35m
|
||
| FlixBus | 11h 10m | 4:50 PM | Talca, ML | Cruce Varoli | 4:00 AM | La Serena | Central Bus Station | Economy | $34 |
A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 10/25/2026 4:50:00 PM to Central Bus Station, La Serena (Chile) arriving at 10/26/2026 4:00:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 11h 10m
|
-
-
FlixBus10h 46m011:30 AMTalca, MLCruce Varoli2:50 PMSantiago, RMTerminal San Borja0BusinessA Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 10/23/2026 11:30:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 10/23/2026 2:50:00 PM. 50 Business ticket for $6 per person are available. Travel duration is 3h 20m
-
Pluss Chile6h 20m03:56 PMSantiago, RMSur Bus Station10:16 PMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 10/23/2026 3:56:00 PM to Central Bus Station, La Serena (Chile) arriving at 10/23/2026 10:16:00 PM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 6h 20m
Waiting Time 1h 6m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 13h 0m | 11:20 AM | Talca, ML | Cruce Varoli | 12:20 AM | La Serena | Central Bus Station | Economy | $20 |
A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 10/26/2026 11:20:00 AM to Central Bus Station, La Serena (Chile) arriving at 10/27/2026 12:20:00 AM. 50 Economy ticket for $20 per person are available. Travel duration is 13h 0m
|
||
| FlixBus | 11h 40m | 10:20 AM | Talca, ML | Cruce Varoli | 10:00 PM | La Serena | Central Bus Station | Economy | $21 |
A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 10/26/2026 10:20:00 AM to Central Bus Station, La Serena (Chile) arriving at 10/26/2026 10:00:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 11h 40m
|
||
| FlixBus | 11h 10m | 4:50 PM | Talca, ML | Cruce Varoli | 4:00 AM | La Serena | Central Bus Station | Economy | $23 |
A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 10/26/2026 4:50:00 PM to Central Bus Station, La Serena (Chile) arriving at 10/27/2026 4:00:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 11h 10m
|
||
| Turbus | 10h 0m | 12:10 PM | Talca, ML | Central Bus Station | 10:10 PM | La Serena | Avda. Fco de Aguirre Station | Premium Economy | $30 |
A Bus from Turbus goes from Central Bus Station, Talca, ML (Chile) at 10/26/2026 12:10:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 10/26/2026 10:10:00 PM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 10h 0m
|
-
-
FlixBus10h 46m011:30 AMTalca, MLCruce Varoli2:50 PMSantiago, RMTerminal San Borja0BusinessA Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 10/23/2026 11:30:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 10/23/2026 2:50:00 PM. 50 Business ticket for $6 per person are available. Travel duration is 3h 20m
-
Pluss Chile6h 20m03:56 PMSantiago, RMSur Bus Station10:16 PMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 10/23/2026 3:56:00 PM to Central Bus Station, La Serena (Chile) arriving at 10/23/2026 10:16:00 PM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 6h 20m
Waiting Time 1h 6m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 13h 0m | 11:20 AM | Talca, ML | Cruce Varoli | 12:20 AM | La Serena | Central Bus Station | Economy | $26 |
A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 10/27/2026 11:20:00 AM to Central Bus Station, La Serena (Chile) arriving at 10/28/2026 12:20:00 AM. 50 Economy ticket for $26 per person are available. Travel duration is 13h 0m
|
||
| Turbus | 10h 0m | 12:10 PM | Talca, ML | Central Bus Station | 10:10 PM | La Serena | Avda. Fco de Aguirre Station | Premium Economy | $30 |
A Bus from Turbus goes from Central Bus Station, Talca, ML (Chile) at 10/27/2026 12:10:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 10/27/2026 10:10:00 PM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 10h 0m
|
-
-
0h 15m0 mi9:50 AMCoquimboBus Station10:05 AMLa SerenaCentral Bus Station378 miTalca, MLFirst ClassA Bus from goes from Bus Station, Coquimbo (Chile) at 10/27/2026 9:50:00 AM to Central Bus Station, La Serena (Chile) arriving at 10/27/2026 10:05:00 AM. 50 First Class ticket for $213 per person are available. Travel duration is 0h 15m
-
-
-
FlixBus10h 46m011:30 AMTalca, MLCruce Varoli2:50 PMSantiago, RMTerminal San Borja0BusinessA Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 10/23/2026 11:30:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 10/23/2026 2:50:00 PM. 50 Business ticket for $6 per person are available. Travel duration is 3h 20m
-
Pluss Chile6h 20m03:56 PMSantiago, RMSur Bus Station10:16 PMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 10/23/2026 3:56:00 PM to Central Bus Station, La Serena (Chile) arriving at 10/23/2026 10:16:00 PM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 6h 20m
Waiting Time 1h 6m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Turbus | 10h 0m | 12:10 PM | Talca, ML | Central Bus Station | 10:10 PM | La Serena | Avda. Fco de Aguirre Station | Premium Economy | $30 |
A Bus from Turbus goes from Central Bus Station, Talca, ML (Chile) at 10/28/2026 12:10:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 10/28/2026 10:10:00 PM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 10h 0m
|
-
-
FlixBus10h 46m011:30 AMTalca, MLCruce Varoli2:50 PMSantiago, RMTerminal San Borja0BusinessA Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 10/23/2026 11:30:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 10/23/2026 2:50:00 PM. 50 Business ticket for $6 per person are available. Travel duration is 3h 20m
-
Pluss Chile6h 20m03:56 PMSantiago, RMSur Bus Station10:16 PMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 10/23/2026 3:56:00 PM to Central Bus Station, La Serena (Chile) arriving at 10/23/2026 10:16:00 PM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 6h 20m
Waiting Time 1h 6m -
Best Price Offer: The price for the cheapest bus from Talca, ML to La Serena is $18 on 10/19/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Talca, ML and La Serena
Facts about the bus from Talca, ML to La Serena
Compare all providers like FlixBus and Turbus that travel 4 times every day by bus from Talca, ML to La Serena in one click! Book your bus ticket from Talca, ML to La Serena starting from $18!
| Cheapest Bus | $18 |
| Fastest Bus | 10h 0m |
| Earliest Bus | 11:20 AM |
| Latest Bus | 12:10 PM |
| Daily Bus Routes | 4 Ø |
| Distance | 382.3 miles |
| Bus Companies | FlixBus and Turbus |
Cheapest bus connections from Talca, ML to La Serena
Every day, 4 buses from 2 bus companies leave Talca, ML for La Serena: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/22/2026 and for the following days.
The cheapest time to travel from Talca, ML to La Serena
How to save money travelling from Talca, ML to La Serena
Book the ticket from Talca, ML to La Serena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Talca, ML to La Serena, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Talca, ML to La Serena are also emptier.All bus stations and stops in Talca, ML and La Serena
In the map below, you can see where to find all bus stations in Talca, ML and La Serena.
Service and Comfort on the bus from Talca, ML to La Serena
FAQs about the Talca, ML to La Serena bus
How much does a Talca, ML La Serena bus trip cost?
How much could I save by comparing buses from Talca, ML to La Serena?
On average, how many connections are available from Talca, ML to La Serena each day?
How long does a bus journey from Talca, ML to La Serena take?
What time is the first bus from Talca, ML to La Serena?
What time is the last bus from Talca, ML to La Serena?
Which bus companies operate the Talca, ML La Serena route?
Is there a direct bus between Talca, ML and La Serena?
What can I take with me on the Talca, ML to La Serena bus route?
What equipment is available for the Talca, ML La Serena bus route?
How does CheckMyBus find the best bus deals from Talca, ML to La Serena?
How does CheckMyBus technology work for trips from Talca, ML to La Serena?
Available seat classes which are offered on the bus route Talca, ML to La Serena
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
More bus routes to Talca, ML and to La Serena
- Bus Routes to Talca, ML
- Bus Castro - Talca, ML
- Buses Concepción - Talca, ML
- Buses from Constitución to Talca, ML
- Buses to Talca, ML from Coquimbo
- Bus from Curicó to Talca, ML
- Bus La Calera to Talca, ML
- Bus to Talca, ML from Lautaro
- Bus Los Ángeles, BI - Talca, ML
- Bus Pucón, AR - Talca, ML
- Buses from Puerto Montt to Talca, ML
- Buses to Talca, ML from San Fernando, LI
- Bus to Talca, ML from Temuco
- Bus to Talca, ML from Valparaíso (CL)
- Bus from Villarrica (CL) to Talca, ML
- Bus Viña del Mar - Talca, ML
- Bus Routes to La Serena
- From Antofagasta to La Serena bus
- From Calama to La Serena bus
- Buses to La Serena from Chillán
- Buses to La Serena from Concepción
- Buses from Curicó to La Serena
- Bus to La Serena from Diego de Almagro
- Buses La Calera - La Serena
- Buses from Los Vilos to La Serena
- Bus Ovalle - La Serena
- Buses Pozo Almonte to La Serena
- Buses Puerto Montt - La Serena
- Rancagua to La Serena bus
- Bus Salamanca, CO - La Serena
- Bus Tocopilla - La Serena
- Vallenar to La Serena bus
