Bus Talca, ML to La Serena: Compare prices and save money

Compare all timetables for the bus from Talca, ML to La Serena

Here is a selection of the cheapest bus trips from the schedule from Talca, ML to La Serena from various bus operators like Turbus or FlixBus for the next days.

today

tomorrow

$32

Friday

Saturday

$26

Sunday

$29

Monday

$35

Tuesday

$32

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Turbus	10h 0m	12:10 PM	Talca, ML	Central Bus Station	10:10 PM	La Serena	Avda. Fco de Aguirre Station		Premium Economy	$32	A Bus from Turbus goes from Central Bus Station, Talca, ML (Chile) at 8/27/2026 12:10:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 8/27/2026 10:10:00 PM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 10h 0m
	Turbus	9h 35m	1:00 PM	Talca, ML	Central Bus Station	10:35 PM	La Serena	Avda. Fco de Aguirre Station		First Class	$42	A Bus from Turbus goes from Central Bus Station, Talca, ML (Chile) at 8/27/2026 1:00:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 8/27/2026 10:35:00 PM. 50 First Class ticket for $42 per person are available. Travel duration is 9h 35m

Did you know that if you travel from Coquimbo to Talca, ML via La Serena, you can save more than $29? You will find the corresponding connections below.
- Save more than 91%
  
  0h 20m
  
  0 mi
  
  11:50 AM
  
  Coquimbo
  Bus Station
  
  12:10 PM
  
  La Serena
  Central Bus Station
  
  378 mi
  
  Talca, ML
  
  First Class
  
  $3
  
  A Bus from goes from Bus Station, Coquimbo (Chile) at 8/27/2026 11:50:00 AM to Central Bus Station, La Serena (Chile) arriving at 8/27/2026 12:10:00 PM. 50 First Class ticket for $3 per person are available. Travel duration is 0h 20m
Did you know that if you travel from Talca, ML to La Serena via Viña del Mar, you can save more than $4? You can find the corresponding connections below.
- Turbus
  
  13h 10m
  
  0
  
  7:10 AM
  
  Talca, ML
  Central Bus Station
  
  12:05 PM
  
  Viña del Mar
  Libertad Bus Station
  
  0
  
  Premium Economy
  
  $17
  
  A Bus from Turbus goes from Central Bus Station, Talca, ML (Chile) at 8/29/2026 7:10:00 AM to Libertad Bus Station, Viña del Mar (Chile) arriving at 8/29/2026 12:05:00 PM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 4h 55m
- Turbus
  
  7h 25m
  
  0
  
  12:55 PM
  
  Viña del Mar
  Libertad Bus Station
  
  8:20 PM
  
  La Serena
  Avda. Fco de Aguirre Station
  
  0
  
  Premium Economy
  
  $11
  
  A Bus from Turbus goes from Libertad Bus Station, Viña del Mar (Chile) at 8/29/2026 12:55:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 8/29/2026 8:20:00 PM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 7h 25m
Travel time is 3h 35m longer, but you will save $4

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	10h 10m	4:50 PM	Talca, ML	Cruce Varoli	3:00 AM	La Serena	Central Bus Station	Economy	$26	A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 8/29/2026 4:50:00 PM to Central Bus Station, La Serena (Chile) arriving at 8/30/2026 3:00:00 AM. 50 Economy ticket for $26 per person are available. Travel duration is 10h 10m
Turbus	10h 0m	12:10 PM	Talca, ML	Central Bus Station	10:10 PM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$32	A Bus from Turbus goes from Central Bus Station, Talca, ML (Chile) at 8/29/2026 12:10:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 8/29/2026 10:10:00 PM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 10h 0m
Turbus	9h 35m	1:00 PM	Talca, ML	Central Bus Station	10:35 PM	La Serena	Avda. Fco de Aguirre Station	First Class	$42	A Bus from Turbus goes from Central Bus Station, Talca, ML (Chile) at 8/29/2026 1:00:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 8/29/2026 10:35:00 PM. 50 First Class ticket for $42 per person are available. Travel duration is 9h 35m

Cheapest bus trips Sunday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	11h 10m	4:50 PM	Talca, ML	Cruce Varoli	4:00 AM	La Serena	Central Bus Station		Economy	$29	A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 8/30/2026 4:50:00 PM to Central Bus Station, La Serena (Chile) arriving at 8/31/2026 4:00:00 AM. 50 Economy ticket for $29 per person are available. Travel duration is 11h 10m

Cheapest bus trips Monday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	11h 10m	4:50 PM	Talca, ML	Cruce Varoli	4:00 AM	La Serena	Central Bus Station		Economy	$35	A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 8/31/2026 4:50:00 PM to Central Bus Station, La Serena (Chile) arriving at 9/1/2026 4:00:00 AM. 50 Economy ticket for $35 per person are available. Travel duration is 11h 10m

Did you know that if you travel from Talca, ML to La Serena via Viña del Mar, you can save more than $8? You can find the corresponding connections below.
- Turbus
  
  13h 15m
  
  0
  
  10:50 AM
  
  Talca, ML
  Central Bus Station
  
  4:20 PM
  
  Viña del Mar
  Libertad Bus Station
  
  0
  
  Premium Economy
  
  $16
  
  A Bus from Turbus goes from Central Bus Station, Talca, ML (Chile) at 8/29/2026 10:50:00 AM to Libertad Bus Station, Viña del Mar (Chile) arriving at 8/29/2026 4:20:00 PM. 50 Premium Economy ticket for $16 per person are available. Travel duration is 5h 30m
- Turbus
  
  5h 45m
  
  0
  
  6:20 PM
  
  Viña del Mar
  Libertad Bus Station
  
  12:05 AM
  
  La Serena
  Avda. Fco de Aguirre Station
  
  0
  
  Premium Economy
  
  $11
  
  A Bus from Turbus goes from Libertad Bus Station, Viña del Mar (Chile) at 8/29/2026 6:20:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 8/30/2026 12:05:00 AM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 5h 45m
Travel time is 2h 5m longer, but you will save $8

Cheapest bus trips Tuesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Turbus	10h 0m	12:10 PM	Talca, ML	Central Bus Station	10:10 PM	La Serena	Avda. Fco de Aguirre Station		Premium Economy	$32	A Bus from Turbus goes from Central Bus Station, Talca, ML (Chile) at 9/1/2026 12:10:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 9/1/2026 10:10:00 PM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 10h 0m
	Turbus	9h 35m	1:00 PM	Talca, ML	Central Bus Station	10:35 PM	La Serena	Avda. Fco de Aguirre Station		First Class	$42	A Bus from Turbus goes from Central Bus Station, Talca, ML (Chile) at 9/1/2026 1:00:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 9/1/2026 10:35:00 PM. 50 First Class ticket for $42 per person are available. Travel duration is 9h 35m

Did you know that if you travel from Coquimbo to Talca, ML via La Serena, you can save more than $27? You will find the corresponding connections below.
- Save more than 84%
  
  0h 20m
  
  0 mi
  
  6:05 AM
  
  Coquimbo
  Bus Station
  
  6:25 AM
  
  La Serena
  Central Bus Station
  
  378 mi
  
  Talca, ML
  
  Premium Economy
  
  $5
  
  A Bus from goes from Bus Station, Coquimbo (Chile) at 9/1/2026 6:05:00 AM to Central Bus Station, La Serena (Chile) arriving at 9/1/2026 6:25:00 AM. 50 Premium Economy ticket for $5 per person are available. Travel duration is 0h 20m
Did you know that if you travel from Talca, ML to La Serena via Viña del Mar, you can save more than $5? You can find the corresponding connections below.
- Turbus
  
  13h 15m
  
  0
  
  10:50 AM
  
  Talca, ML
  Central Bus Station
  
  4:20 PM
  
  Viña del Mar
  Libertad Bus Station
  
  0
  
  Premium Economy
  
  $16
  
  A Bus from Turbus goes from Central Bus Station, Talca, ML (Chile) at 8/29/2026 10:50:00 AM to Libertad Bus Station, Viña del Mar (Chile) arriving at 8/29/2026 4:20:00 PM. 50 Premium Economy ticket for $16 per person are available. Travel duration is 5h 30m
- Turbus
  
  5h 45m
  
  0
  
  6:20 PM
  
  Viña del Mar
  Libertad Bus Station
  
  12:05 AM
  
  La Serena
  Avda. Fco de Aguirre Station
  
  0
  
  Premium Economy
  
  $11
  
  A Bus from Turbus goes from Libertad Bus Station, Viña del Mar (Chile) at 8/29/2026 6:20:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 8/30/2026 12:05:00 AM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 5h 45m
Travel time is 3h 40m longer, but you will save $5

Best Price Offer: The price for the cheapest bus from Talca, ML to La Serena is $26 on 8/29/2026. Flexible travelers save on ticket prices.

Facts about the bus from Talca, ML to La Serena

Compare all providers like Turbus and FlixBus that travel 1 times every day by bus from Talca, ML to La Serena in one click! Book your bus ticket from Talca, ML to La Serena starting from $26!

Cheapest Bus	$26
Fastest Bus	9h 35m
Earliest Bus	12:10 PM
Latest Bus	1:00 PM
Daily Bus Routes	1 Ø
Distance	382.3 miles
Bus Companies	Turbus and FlixBus

Cheapest bus connections from Talca, ML to La Serena

Every day, 1 buses from 2 bus companies leave Talca, ML for La Serena: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 08/26/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 08/23

Monday 08/24

Tuesday 08/25

Wednesday 08/26

Thursday 08/27

$32

Friday 08/28

Saturday 08/29

$26

Sunday 08/30

$29

Monday 08/31

$35

Tuesday 09/01

$32

Wednesday 09/02

Thursday 09/03

$35

Friday 09/04

$41

Saturday 09/05

$32

Sunday 09/06

$41

Monday 09/07

$36

Tuesday 09/08

$32

Wednesday 09/09

Thursday 09/10

$27

Friday 09/11

Saturday 09/12

Sunday 09/13

Monday 09/14

$28

Tuesday 09/15

$37

Wednesday 09/16

Thursday 09/17

$40

Friday 09/18

$44

Saturday 09/19

How to save money travelling from Talca, ML to La Serena

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Talca, ML to La Serena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Talca, ML to La Serena, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Talca, ML to La Serena are also emptier.

All bus stations and stops in Talca, ML and La Serena

In the map below, you can see where to find all bus stations in Talca, ML and La Serena.

Central Bus Station

Dos Sur 1932

Cruce Varoli

Terminal

Calle 1 Norte / 18 ote

Cruce Ruta 5

Avda. Fco de Aguirre Station

Avenida Francisco de Aguirre 410

Central Bus Station

Avenida El Santo 1475

terminal de buses covalle bus

El Sto, 1060

Rotonda

Service and Comfort on the bus from Talca, ML to La Serena

Want to know which seat classes are available on the buses from Talca, ML to La Serena? Or which bus companies serve the route Talca, ML to La Serena? Below you will find answers to your questions.

FAQs about the Talca, ML to La Serena bus

How much does a Talca, ML La Serena bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $26 and takes 10h 10m to reach La Serena. Compare offers to save money!

How much could I save by comparing buses from Talca, ML to La Serena?

This route is offered by 2 companies with a range of ticket prices between $26 and $42. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to La Serena.

On average, how many connections are available from Talca, ML to La Serena each day?

Every day, the Talca, ML to La Serena bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Talca, ML to La Serena take?

The fastest bus from Talca, ML to La Serena is offered by Turbus and takes 9h 35m. Bus tickets for this connection cost $42. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Talca, ML to La Serena?

The earliest bus arriving in La Serena from Talca, ML starts at 12:10 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Talca, ML to La Serena?

The latest bus trip departing from Talca, ML for La Serena starts at 1:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Talca, ML La Serena route?

When traveling by bus from Talca, ML to La Serena, passengers can travel with Turbus and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Talca, ML and La Serena?

You can check all the direct connections between Talca, ML and La Serena by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Turbus and FlixBus.

What can I take with me on the Talca, ML to La Serena bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Talca, ML La Serena bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Talca, ML La Serena bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Talca, ML to La Serena on your planned travel date.

How does CheckMyBus find the best bus deals from Talca, ML to La Serena?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 1 daily trips between Talca, ML and La Serena. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Talca, ML to La Serena?

Prices and availability for 1 trips between Talca, ML and La Serena change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Talca, ML to La Serena

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

First Class

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Talca, ML and to La Serena

Here’s an overview of the most popular bus routes to Talca, ML and to La Serena. Simply click on the connection of your choice, and you will find all the details about your bus route!