Bus from Siracusa to Rome from $46

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Compare all timetables for the bus from Siracusa to Rome

Here is a selection of the cheapest bus trips from the schedule from Siracusa to Rome from various bus operators like FlixBus or Trenitalia for the next days.

today
$86
tomorrow
$55
Sunday
$85
Monday
$76
Tuesday
$78
Wednesday
Thursday
$70

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Trenitalia 12h 44m 5:50 AM Siracusa Central Station 6:34 PM Rome Termini Central Station  Economy $86
FlixBus 14h 15m 7:15 AM Siracusa Corso Umberto Bus Station 9:30 PM Rome Tiburtina Bus Station  Economy $99
FlixBus 13h 30m 5:20 PM Siracusa Corso Umberto Bus Station 6:50 AM Rome Tiburtina Bus Station  Economy $102
FlixBus 18h 30m 5:20 PM Siracusa Corso Umberto Bus Station 11:50 AM Rome Anagnina Bus Station  Economy $113
  • Did you know that if you travel from Siracusa to Rome via Messina, you can save more than $73? You can find the corresponding connections below.
    • FlixBus
      8h 10m
      0
      7:15 AM
      Siracusa
      Corso Umberto Bus Station
      10:00 AM
      Messina
      Piazza della Repubblica
      0
      FlixBus
      Economy
      $10
      • Waiting Time 4h 15m
    • Interbus
      1h 10m
      0
      2:15 PM
      Messina
      Central Station
      3:25 PM
      Rome
      Appia/Quarto Miglio
      0
      Interbus
      Economy
      $3
    Travel Time is 4h 34m shorter, and you will save $73

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 19h 30m 5:20 PM Siracusa Corso Umberto Bus Station 11:50 AM Rome Anagnina Bus Station  Economy $55
FlixBus 13h 30m 5:20 PM Siracusa Corso Umberto Bus Station 5:50 AM Rome Tiburtina Bus Station  Economy $56
FlixBus 14h 15m 7:15 AM Siracusa Corso Umberto Bus Station 9:30 PM Rome Tiburtina Bus Station  Economy $69
  • Did you know that if you travel from Siracusa to Rome via Messina, you can save more than $42? You can find the corresponding connections below.
    • FlixBus
      8h 10m
      0
      7:15 AM
      Siracusa
      Corso Umberto Bus Station
      10:00 AM
      Messina
      Piazza della Repubblica
      0
      FlixBus
      Economy
      $10
      • Waiting Time 4h 15m
    • Interbus
      1h 10m
      0
      2:15 PM
      Messina
      Central Station
      3:25 PM
      Rome
      Appia/Quarto Miglio
      0
      Interbus
      Economy
      $3
    Travel Time is 4h 20m shorter, and you will save $42

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 18h 30m 5:20 PM Siracusa Corso Umberto Bus Station 11:50 AM Rome Anagnina Bus Station  Economy $85
FlixBus 14h 15m 7:15 AM Siracusa Corso Umberto Bus Station 9:30 PM Rome Tiburtina Bus Station  Economy $97
FlixBus 13h 30m 5:20 PM Siracusa Corso Umberto Bus Station 6:50 AM Rome Tiburtina Bus Station  Economy $102
  • Did you know that if you travel from Siracusa to Rome via Messina, you can save more than $72? You can find the corresponding connections below.
    • FlixBus
      8h 10m
      0
      7:15 AM
      Siracusa
      Corso Umberto Bus Station
      10:00 AM
      Messina
      Piazza della Repubblica
      0
      FlixBus
      Economy
      $10
      • Waiting Time 4h 15m
    • Interbus
      1h 10m
      0
      2:15 PM
      Messina
      Central Station
      3:25 PM
      Rome
      Appia/Quarto Miglio
      0
      Interbus
      Economy
      $3
    Travel Time is 5h 20m shorter, and you will save $72

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 14h 15m 7:15 AM Siracusa Corso Umberto Bus Station 9:30 PM Rome Tiburtina Bus Station  Economy $76
FlixBus 13h 30m 5:20 PM Siracusa Corso Umberto Bus Station 6:50 AM Rome Tiburtina Bus Station  Economy $85
  • Did you know that if you travel from Siracusa to Rome via Messina, you can save more than $63? You can find the corresponding connections below.
    • FlixBus
      8h 10m
      0
      7:15 AM
      Siracusa
      Corso Umberto Bus Station
      10:00 AM
      Messina
      Piazza della Repubblica
      0
      FlixBus
      Economy
      $10
      • Waiting Time 4h 15m
    • Interbus
      1h 10m
      0
      2:15 PM
      Messina
      Central Station
      3:25 PM
      Rome
      Appia/Quarto Miglio
      0
      Interbus
      Economy
      $3
    Travel Time is 5h 20m shorter, and you will save $63

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 14h 15m 7:15 AM Siracusa Corso Umberto Bus Station 9:30 PM Rome Tiburtina Bus Station  Economy $78
FlixBus 13h 30m 5:20 PM Siracusa Corso Umberto Bus Station 6:50 AM Rome Tiburtina Bus Station  Economy $79
  • Did you know that if you travel from Siracusa to Rome via Messina, you can save more than $65? You can find the corresponding connections below.
    • FlixBus
      8h 10m
      0
      7:15 AM
      Siracusa
      Corso Umberto Bus Station
      10:00 AM
      Messina
      Piazza della Repubblica
      0
      FlixBus
      Economy
      $10
      • Waiting Time 4h 15m
    • Interbus
      1h 10m
      0
      2:15 PM
      Messina
      Central Station
      3:25 PM
      Rome
      Appia/Quarto Miglio
      0
      Interbus
      Economy
      $3
    Travel Time is 5h 20m shorter, and you will save $65

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 13h 30m 5:20 PM Siracusa Corso Umberto Bus Station 6:50 AM Rome Tiburtina Bus Station  Economy $70
FlixBus 18h 30m 5:20 PM Siracusa Corso Umberto Bus Station 11:50 AM Rome Anagnina Bus Station  Economy $70
FlixBus 14h 15m 7:15 AM Siracusa Corso Umberto Bus Station 9:30 PM Rome Tiburtina Bus Station  Economy $77
  • Did you know that if you travel from Siracusa to Rome via Messina, you can save more than $57? You can find the corresponding connections below.
    • FlixBus
      8h 10m
      0
      7:15 AM
      Siracusa
      Corso Umberto Bus Station
      10:00 AM
      Messina
      Piazza della Repubblica
      0
      FlixBus
      Economy
      $10
      • Waiting Time 4h 15m
    • Interbus
      1h 10m
      0
      2:15 PM
      Messina
      Central Station
      3:25 PM
      Rome
      Appia/Quarto Miglio
      0
      Interbus
      Economy
      $3
    Travel Time is 5h 20m shorter, and you will save $57

Best Price Offer: The price for the cheapest bus from Siracusa to Rome is $46 on 11/12/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Siracusa and Rome

See here how frequent the connections between Siracusa and Rome are, during different times and days of the week.
Friday is the busiest day, with more than 4 daily buses from Siracusa to Rome. Monday has instead the fewest connections, with only 2 daily coaches between Siracusa and Rome.
The busiest time of the day is the Afternoon, with 10 buses from Siracusa to Rome, while Night sees the fewest connections between Siracusa and Rome, with 1 offers.

Facts about the bus from Siracusa to Rome

Compare all providers like FlixBus and Trenitalia that travel 2 times every day by bus from Siracusa to Rome in one click! Book your bus ticket from Siracusa to Rome starting from $46!

Cheapest Bus $46
Fastest Bus 12h 30m
Earliest Bus 5:50 AM
Latest Bus 5:20 PM
Daily Bus Routes 2 Ø
Distance 365.2 miles
Bus Companies FlixBus and Trenitalia

Cheapest bus connections from Siracusa to Rome

Every day, 2 buses from 2 bus companies leave Siracusa for Rome: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/23/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 10/18
Monday 10/19
Tuesday 10/20
Wednesday 10/21
Thursday 10/22
Friday 10/23
$86
Saturday 10/24
$55
Sunday 10/25
$85
Monday 10/26
$76
Tuesday 10/27
$78
Wednesday 10/28
Thursday 10/29
$70
Friday 10/30
$57
Saturday 10/31
$61
Sunday 11/01
Monday 11/02
$66
Tuesday 11/03
$84
Wednesday 11/04
$79
Thursday 11/05
$75
Friday 11/06
$59
Saturday 11/07
Sunday 11/08
$72
Monday 11/09
$53
Tuesday 11/10
Wednesday 11/11
Thursday 11/12
$46
Friday 11/13
Saturday 11/14

The cheapest time to travel from Siracusa to Rome

See here on which day and which time of the day you can find the cheapest bus ticket from Siracusa to Rome, for the next 30 days.
With a price starting from $46, Thursday is the cheapest day for a bus from Siracusa to Rome. Sunday instead is the most expensive day with prices starting from $72.
Night is the cheapest day time for bus tickets from Siracusa to Rome, with $46. Morning is the most expensive time of the day with prices starting from $69.

How to save money travelling from Siracusa to Rome

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Siracusa to Rome in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Siracusa to Rome, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Siracusa to Rome are also emptier.

Beloved bus companies from Siracusa to Rome

These are the most booked bus companies between Siracusa to Rome from our users.

Trenitalia from Siracusa to Rome

Trenitalia

Here you will find the key facts about the Trenitalia bus route Siracusa to Rome:

Cheapest Price $86
Fastest Bus 12h 44m
Earliest Bus 5:50 AM
Last Bus 5:50 AM
Daily Connections 1 Ø
Found on 10/22/2026

All bus stations and stops in Siracusa and Rome

In the map below, you can see where to find all bus stations in Siracusa and Rome.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Siracusa to Rome? Compare all modes of transports from Siracusa to Rome.

Service and Comfort on the bus from Siracusa to Rome

Want to know which seat classes are available on the buses from Siracusa to Rome? Or which bus companies serve the route Siracusa to Rome? Below you will find answers to your questions.

FAQs about the Siracusa to Rome bus

How much does a Siracusa Rome bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $46 and takes 18h 30m to reach Rome. Compare offers to save money!

How much could I save by comparing buses from Siracusa to Rome?

This route is offered by 2 companies with a range of ticket prices between $46 and $113. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Rome.

On average, how many connections are available from Siracusa to Rome each day?

Every day, the Siracusa to Rome bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Siracusa to Rome take?

The fastest bus from Siracusa to Rome is offered by FlixBus and takes 12h 30m. Bus tickets for this connection cost $56. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Siracusa to Rome?

The earliest bus arriving in Rome from Siracusa starts at 5:50 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Siracusa to Rome?

The latest bus trip departing from Siracusa for Rome starts at 5:20 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Siracusa Rome route?

When traveling by bus from Siracusa to Rome, passengers can travel with FlixBus and Trenitalia. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Siracusa and Rome?

You can check all the direct connections between Siracusa and Rome by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Trenitalia.

What can I take with me on the Siracusa to Rome bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Siracusa Rome bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Siracusa Rome bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Siracusa to Rome on your planned travel date.

How does CheckMyBus find the best bus deals from Siracusa to Rome?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Siracusa and Rome. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Siracusa to Rome?

Prices and availability for 2 trips between Siracusa and Rome change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Siracusa to Rome

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Siracusa and to Rome

Here’s an overview of the most popular bus routes to Siracusa and to Rome. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses from Letojanni to Siracusa Buses from Letojanni to Siracusa
Buses from Marina di Ragusa to Siracusa Buses from Marina di Ragusa to Siracusa
Buses from Todi to Siracusa Buses from Todi to Siracusa
Buses Caltagirone - Siracusa Buses Caltagirone - Siracusa
Hanover to Rome bus Hanover to Rome bus
Buses Oslo to Rome Buses Oslo to Rome
Buses Marseille to Rome Buses Marseille to Rome
Buses to Rome from Sora Buses to Rome from Sora
Popular Airport Shuttles to Siracusa and to Rome
CheckMyBus › Buses in Italy › Bus to Siracusa › Bus to Rome

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