Bus Santiago del Estero to Mendoza: Compare prices and save money

Compare all timetables for the bus from Santiago del Estero to Mendoza

Here is a selection of the cheapest bus trips from the schedule from Santiago del Estero to Mendoza from various bus operators like 20 de Junio, Andesmar or Autotransportes San Juan for the next days.

today

$99

tomorrow

$99

Monday

$99

Tuesday

$99

Wednesday

$99

Thursday

$99

Friday

$99

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Andesmar	17h 15m	5:15 PM	Santiago del Estero	Central Bus Station	10:30 AM	Mendoza	Bus Station	Premium Economy	$99	A Bus from Andesmar goes from Central Bus Station, Santiago del Estero (Argentina) at 10/24/2026 5:15:00 PM to Bus Station, Mendoza (Argentina) arriving at 10/25/2026 10:30:00 AM. 50 Premium Economy ticket for $99 per person are available. Travel duration is 17h 15m
Autotransportes San Juan	18h 45m	2:15 PM	Santiago del Estero	Central Bus Station	9:00 AM	Mendoza	Bus Station	Premium Economy	$99	A Bus from Autotransportes San Juan goes from Central Bus Station, Santiago del Estero (Argentina) at 10/24/2026 2:15:00 PM to Bus Station, Mendoza (Argentina) arriving at 10/25/2026 9:00:00 AM. 50 Premium Economy ticket for $99 per person are available. Travel duration is 18h 45m
20 de Junio	17h 15m	6:40 AM	Santiago del Estero	Central Bus Station	11:55 PM	Mendoza	Bus Station	Premium Economy	$116	A Bus from 20 de Junio goes from Central Bus Station, Santiago del Estero (Argentina) at 10/24/2026 6:40:00 AM to Bus Station, Mendoza (Argentina) arriving at 10/24/2026 11:55:00 PM. 50 Premium Economy ticket for $116 per person are available. Travel duration is 17h 15m

Did you know that if you travel from Santiago del Estero to Mendoza via Córdoba, CD, you can save more than $47? You can find the corresponding connections below.
- Vía Tac
  
  22h 39m
  
  0
  
  8:26 AM
  
  Santiago del Estero
  Central Bus Station
  
  4:46 PM
  
  Córdoba, CD
  Bus Station
  
  0
  
  Premium Economy
  
  $20
  
  A Bus from Vía Tac goes from Central Bus Station, Santiago del Estero (Argentina) at 10/25/2026 8:26:00 AM to Bus Station, Córdoba, CD (Argentina) arriving at 10/25/2026 4:46:00 PM. 50 Premium Economy ticket for $20 per person are available. Travel duration is 8h 20m
- Vía Tac
  
  10h 35m
  
  0
  
  8:30 PM
  
  Córdoba, CD
  Bus Station
  
  7:05 AM
  
  Mendoza
  Bus Station
  
  0
  
  Premium Economy
  
  $32
  
  A Bus from Vía Tac goes from Bus Station, Córdoba, CD (Argentina) at 10/25/2026 8:30:00 PM to Bus Station, Mendoza (Argentina) arriving at 10/26/2026 7:05:00 AM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 10h 35m
Travel time is 5h 24m longer, but you will save $47

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Andesmar	17h 15m	5:15 PM	Santiago del Estero	Central Bus Station	10:30 AM	Mendoza	Bus Station	Premium Economy	$99	A Bus from Andesmar goes from Central Bus Station, Santiago del Estero (Argentina) at 10/25/2026 5:15:00 PM to Bus Station, Mendoza (Argentina) arriving at 10/26/2026 10:30:00 AM. 50 Premium Economy ticket for $99 per person are available. Travel duration is 17h 15m
Autotransportes San Juan	17h 20m	12:20 AM	Santiago del Estero	Central Bus Station	5:40 PM	Mendoza	Bus Station	Premium Economy	$104	A Bus from Autotransportes San Juan goes from Central Bus Station, Santiago del Estero (Argentina) at 10/25/2026 12:20:00 AM to Bus Station, Mendoza (Argentina) arriving at 10/25/2026 5:40:00 PM. 50 Premium Economy ticket for $104 per person are available. Travel duration is 17h 20m
Autotransportes San Juan	18h 45m	2:15 PM	Santiago del Estero	Central Bus Station	9:00 AM	Mendoza	Bus Station	Premium Economy	$104	A Bus from Autotransportes San Juan goes from Central Bus Station, Santiago del Estero (Argentina) at 10/25/2026 2:15:00 PM to Bus Station, Mendoza (Argentina) arriving at 10/26/2026 9:00:00 AM. 50 Premium Economy ticket for $104 per person are available. Travel duration is 18h 45m
20 de Junio	17h 45m	1:15 AM	Santiago del Estero	Central Bus Station	7:00 PM	Mendoza	Bus Station	Economy	$107	A Bus from 20 de Junio goes from Central Bus Station, Santiago del Estero (Argentina) at 10/25/2026 1:15:00 AM to Bus Station, Mendoza (Argentina) arriving at 10/25/2026 7:00:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 17h 45m
20 de Junio	17h 15m	6:40 AM	Santiago del Estero	Central Bus Station	11:55 PM	Mendoza	Bus Station	Premium Economy	$116	A Bus from 20 de Junio goes from Central Bus Station, Santiago del Estero (Argentina) at 10/25/2026 6:40:00 AM to Bus Station, Mendoza (Argentina) arriving at 10/25/2026 11:55:00 PM. 50 Premium Economy ticket for $116 per person are available. Travel duration is 17h 15m

Did you know that if you travel from Santiago del Estero to Mendoza via Córdoba, CD, you can save more than $47? You can find the corresponding connections below.
- Vía Tac
  
  22h 39m
  
  0
  
  8:26 AM
  
  Santiago del Estero
  Central Bus Station
  
  4:46 PM
  
  Córdoba, CD
  Bus Station
  
  0
  
  Premium Economy
  
  $20
  
  A Bus from Vía Tac goes from Central Bus Station, Santiago del Estero (Argentina) at 10/25/2026 8:26:00 AM to Bus Station, Córdoba, CD (Argentina) arriving at 10/25/2026 4:46:00 PM. 50 Premium Economy ticket for $20 per person are available. Travel duration is 8h 20m
- Vía Tac
  
  10h 35m
  
  0
  
  8:30 PM
  
  Córdoba, CD
  Bus Station
  
  7:05 AM
  
  Mendoza
  Bus Station
  
  0
  
  Premium Economy
  
  $32
  
  A Bus from Vía Tac goes from Bus Station, Córdoba, CD (Argentina) at 10/25/2026 8:30:00 PM to Bus Station, Mendoza (Argentina) arriving at 10/26/2026 7:05:00 AM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 10h 35m
Travel time is 5h 24m longer, but you will save $47

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Andesmar	17h 15m	5:15 PM	Santiago del Estero	Central Bus Station	10:30 AM	Mendoza	Bus Station	Premium Economy	$99	A Bus from Andesmar goes from Central Bus Station, Santiago del Estero (Argentina) at 10/26/2026 5:15:00 PM to Bus Station, Mendoza (Argentina) arriving at 10/27/2026 10:30:00 AM. 50 Premium Economy ticket for $99 per person are available. Travel duration is 17h 15m
20 de Junio	17h 15m	6:40 AM	Santiago del Estero	Central Bus Station	11:55 PM	Mendoza	Bus Station	Premium Economy	$103	A Bus from 20 de Junio goes from Central Bus Station, Santiago del Estero (Argentina) at 10/26/2026 6:40:00 AM to Bus Station, Mendoza (Argentina) arriving at 10/26/2026 11:55:00 PM. 50 Premium Economy ticket for $103 per person are available. Travel duration is 17h 15m
Autotransportes San Juan	17h 20m	12:20 AM	Santiago del Estero	Central Bus Station	5:40 PM	Mendoza	Bus Station	Premium Economy	$104	A Bus from Autotransportes San Juan goes from Central Bus Station, Santiago del Estero (Argentina) at 10/26/2026 12:20:00 AM to Bus Station, Mendoza (Argentina) arriving at 10/26/2026 5:40:00 PM. 50 Premium Economy ticket for $104 per person are available. Travel duration is 17h 20m
Autotransportes San Juan	18h 45m	2:15 PM	Santiago del Estero	Central Bus Station	9:00 AM	Mendoza	Bus Station	Premium Economy	$104	A Bus from Autotransportes San Juan goes from Central Bus Station, Santiago del Estero (Argentina) at 10/26/2026 2:15:00 PM to Bus Station, Mendoza (Argentina) arriving at 10/27/2026 9:00:00 AM. 50 Premium Economy ticket for $104 per person are available. Travel duration is 18h 45m
20 de Junio	17h 45m	1:15 AM	Santiago del Estero	Central Bus Station	7:00 PM	Mendoza	Bus Station	Economy	$107	A Bus from 20 de Junio goes from Central Bus Station, Santiago del Estero (Argentina) at 10/26/2026 1:15:00 AM to Bus Station, Mendoza (Argentina) arriving at 10/26/2026 7:00:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 17h 45m

Did you know that if you travel from Santiago del Estero to Mendoza via Córdoba, CD, you can save more than $47? You can find the corresponding connections below.
- Vía Tac
  
  22h 39m
  
  0
  
  8:26 AM
  
  Santiago del Estero
  Central Bus Station
  
  4:46 PM
  
  Córdoba, CD
  Bus Station
  
  0
  
  Premium Economy
  
  $20
  
  A Bus from Vía Tac goes from Central Bus Station, Santiago del Estero (Argentina) at 10/25/2026 8:26:00 AM to Bus Station, Córdoba, CD (Argentina) arriving at 10/25/2026 4:46:00 PM. 50 Premium Economy ticket for $20 per person are available. Travel duration is 8h 20m
- Vía Tac
  
  10h 35m
  
  0
  
  8:30 PM
  
  Córdoba, CD
  Bus Station
  
  7:05 AM
  
  Mendoza
  Bus Station
  
  0
  
  Premium Economy
  
  $32
  
  A Bus from Vía Tac goes from Bus Station, Córdoba, CD (Argentina) at 10/25/2026 8:30:00 PM to Bus Station, Mendoza (Argentina) arriving at 10/26/2026 7:05:00 AM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 10h 35m
Travel time is 5h 24m longer, but you will save $47

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Andesmar	17h 15m	5:15 PM	Santiago del Estero	Central Bus Station	10:30 AM	Mendoza	Bus Station	Premium Economy	$99	A Bus from Andesmar goes from Central Bus Station, Santiago del Estero (Argentina) at 10/27/2026 5:15:00 PM to Bus Station, Mendoza (Argentina) arriving at 10/28/2026 10:30:00 AM. 50 Premium Economy ticket for $99 per person are available. Travel duration is 17h 15m
20 de Junio	17h 15m	6:40 AM	Santiago del Estero	Central Bus Station	11:55 PM	Mendoza	Bus Station	Premium Economy	$103	A Bus from 20 de Junio goes from Central Bus Station, Santiago del Estero (Argentina) at 10/27/2026 6:40:00 AM to Bus Station, Mendoza (Argentina) arriving at 10/27/2026 11:55:00 PM. 50 Premium Economy ticket for $103 per person are available. Travel duration is 17h 15m
Autotransportes San Juan	17h 20m	12:20 AM	Santiago del Estero	Central Bus Station	5:40 PM	Mendoza	Bus Station	Premium Economy	$104	A Bus from Autotransportes San Juan goes from Central Bus Station, Santiago del Estero (Argentina) at 10/27/2026 12:20:00 AM to Bus Station, Mendoza (Argentina) arriving at 10/27/2026 5:40:00 PM. 50 Premium Economy ticket for $104 per person are available. Travel duration is 17h 20m
Autotransportes San Juan	18h 45m	2:15 PM	Santiago del Estero	Central Bus Station	9:00 AM	Mendoza	Bus Station	Premium Economy	$104	A Bus from Autotransportes San Juan goes from Central Bus Station, Santiago del Estero (Argentina) at 10/27/2026 2:15:00 PM to Bus Station, Mendoza (Argentina) arriving at 10/28/2026 9:00:00 AM. 50 Premium Economy ticket for $104 per person are available. Travel duration is 18h 45m
20 de Junio	17h 45m	1:15 AM	Santiago del Estero	Central Bus Station	7:00 PM	Mendoza	Bus Station	Economy	$107	A Bus from 20 de Junio goes from Central Bus Station, Santiago del Estero (Argentina) at 10/27/2026 1:15:00 AM to Bus Station, Mendoza (Argentina) arriving at 10/27/2026 7:00:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 17h 45m

Did you know that if you travel from Santiago del Estero to Mendoza via Córdoba, CD, you can save more than $47? You can find the corresponding connections below.
- Vía Tac
  
  22h 39m
  
  0
  
  8:26 AM
  
  Santiago del Estero
  Central Bus Station
  
  4:46 PM
  
  Córdoba, CD
  Bus Station
  
  0
  
  Premium Economy
  
  $20
  
  A Bus from Vía Tac goes from Central Bus Station, Santiago del Estero (Argentina) at 10/25/2026 8:26:00 AM to Bus Station, Córdoba, CD (Argentina) arriving at 10/25/2026 4:46:00 PM. 50 Premium Economy ticket for $20 per person are available. Travel duration is 8h 20m
- Vía Tac
  
  10h 35m
  
  0
  
  8:30 PM
  
  Córdoba, CD
  Bus Station
  
  7:05 AM
  
  Mendoza
  Bus Station
  
  0
  
  Premium Economy
  
  $32
  
  A Bus from Vía Tac goes from Bus Station, Córdoba, CD (Argentina) at 10/25/2026 8:30:00 PM to Bus Station, Mendoza (Argentina) arriving at 10/26/2026 7:05:00 AM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 10h 35m
Travel time is 5h 24m longer, but you will save $47

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Andesmar	17h 15m	5:15 PM	Santiago del Estero	Central Bus Station	10:30 AM	Mendoza	Bus Station	Premium Economy	$99	A Bus from Andesmar goes from Central Bus Station, Santiago del Estero (Argentina) at 10/28/2026 5:15:00 PM to Bus Station, Mendoza (Argentina) arriving at 10/29/2026 10:30:00 AM. 50 Premium Economy ticket for $99 per person are available. Travel duration is 17h 15m
Autotransportes San Juan	17h 20m	12:20 AM	Santiago del Estero	Central Bus Station	5:40 PM	Mendoza	Bus Station	Premium Economy	$104	A Bus from Autotransportes San Juan goes from Central Bus Station, Santiago del Estero (Argentina) at 10/28/2026 12:20:00 AM to Bus Station, Mendoza (Argentina) arriving at 10/28/2026 5:40:00 PM. 50 Premium Economy ticket for $104 per person are available. Travel duration is 17h 20m
Autotransportes San Juan	18h 45m	2:15 PM	Santiago del Estero	Central Bus Station	9:00 AM	Mendoza	Bus Station	Premium Economy	$104	A Bus from Autotransportes San Juan goes from Central Bus Station, Santiago del Estero (Argentina) at 10/28/2026 2:15:00 PM to Bus Station, Mendoza (Argentina) arriving at 10/29/2026 9:00:00 AM. 50 Premium Economy ticket for $104 per person are available. Travel duration is 18h 45m
20 de Junio	17h 45m	1:15 AM	Santiago del Estero	Central Bus Station	7:00 PM	Mendoza	Bus Station	Economy	$107	A Bus from 20 de Junio goes from Central Bus Station, Santiago del Estero (Argentina) at 10/28/2026 1:15:00 AM to Bus Station, Mendoza (Argentina) arriving at 10/28/2026 7:00:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 17h 45m
20 de Junio	17h 15m	6:40 AM	Santiago del Estero	Central Bus Station	11:55 PM	Mendoza	Bus Station	Premium Economy	$116	A Bus from 20 de Junio goes from Central Bus Station, Santiago del Estero (Argentina) at 10/28/2026 6:40:00 AM to Bus Station, Mendoza (Argentina) arriving at 10/28/2026 11:55:00 PM. 50 Premium Economy ticket for $116 per person are available. Travel duration is 17h 15m

Did you know that if you travel from Santiago del Estero to Mendoza via Córdoba, CD, you can save more than $47? You can find the corresponding connections below.
- Vía Tac
  
  22h 39m
  
  0
  
  8:26 AM
  
  Santiago del Estero
  Central Bus Station
  
  4:46 PM
  
  Córdoba, CD
  Bus Station
  
  0
  
  Premium Economy
  
  $20
  
  A Bus from Vía Tac goes from Central Bus Station, Santiago del Estero (Argentina) at 10/25/2026 8:26:00 AM to Bus Station, Córdoba, CD (Argentina) arriving at 10/25/2026 4:46:00 PM. 50 Premium Economy ticket for $20 per person are available. Travel duration is 8h 20m
- Vía Tac
  
  10h 35m
  
  0
  
  8:30 PM
  
  Córdoba, CD
  Bus Station
  
  7:05 AM
  
  Mendoza
  Bus Station
  
  0
  
  Premium Economy
  
  $32
  
  A Bus from Vía Tac goes from Bus Station, Córdoba, CD (Argentina) at 10/25/2026 8:30:00 PM to Bus Station, Mendoza (Argentina) arriving at 10/26/2026 7:05:00 AM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 10h 35m
Travel time is 5h 24m longer, but you will save $47

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Andesmar	17h 15m	5:15 PM	Santiago del Estero	Central Bus Station	10:30 AM	Mendoza	Bus Station	Premium Economy	$99	A Bus from Andesmar goes from Central Bus Station, Santiago del Estero (Argentina) at 10/29/2026 5:15:00 PM to Bus Station, Mendoza (Argentina) arriving at 10/30/2026 10:30:00 AM. 50 Premium Economy ticket for $99 per person are available. Travel duration is 17h 15m
Autotransportes San Juan	17h 20m	12:20 AM	Santiago del Estero	Central Bus Station	5:40 PM	Mendoza	Bus Station	Premium Economy	$104	A Bus from Autotransportes San Juan goes from Central Bus Station, Santiago del Estero (Argentina) at 10/29/2026 12:20:00 AM to Bus Station, Mendoza (Argentina) arriving at 10/29/2026 5:40:00 PM. 50 Premium Economy ticket for $104 per person are available. Travel duration is 17h 20m
Autotransportes San Juan	18h 45m	2:15 PM	Santiago del Estero	Central Bus Station	9:00 AM	Mendoza	Bus Station	Premium Economy	$104	A Bus from Autotransportes San Juan goes from Central Bus Station, Santiago del Estero (Argentina) at 10/29/2026 2:15:00 PM to Bus Station, Mendoza (Argentina) arriving at 10/30/2026 9:00:00 AM. 50 Premium Economy ticket for $104 per person are available. Travel duration is 18h 45m
20 de Junio	17h 45m	1:15 AM	Santiago del Estero	Central Bus Station	7:00 PM	Mendoza	Bus Station	Economy	$107	A Bus from 20 de Junio goes from Central Bus Station, Santiago del Estero (Argentina) at 10/29/2026 1:15:00 AM to Bus Station, Mendoza (Argentina) arriving at 10/29/2026 7:00:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 17h 45m
20 de Junio	17h 15m	6:40 AM	Santiago del Estero	Central Bus Station	11:55 PM	Mendoza	Bus Station	Premium Economy	$116	A Bus from 20 de Junio goes from Central Bus Station, Santiago del Estero (Argentina) at 10/29/2026 6:40:00 AM to Bus Station, Mendoza (Argentina) arriving at 10/29/2026 11:55:00 PM. 50 Premium Economy ticket for $116 per person are available. Travel duration is 17h 15m

Did you know that if you travel from Santiago del Estero to Mendoza via Córdoba, CD, you can save more than $47? You can find the corresponding connections below.
- Vía Tac
  
  22h 39m
  
  0
  
  8:26 AM
  
  Santiago del Estero
  Central Bus Station
  
  4:46 PM
  
  Córdoba, CD
  Bus Station
  
  0
  
  Premium Economy
  
  $20
  
  A Bus from Vía Tac goes from Central Bus Station, Santiago del Estero (Argentina) at 10/25/2026 8:26:00 AM to Bus Station, Córdoba, CD (Argentina) arriving at 10/25/2026 4:46:00 PM. 50 Premium Economy ticket for $20 per person are available. Travel duration is 8h 20m
- Vía Tac
  
  10h 35m
  
  0
  
  8:30 PM
  
  Córdoba, CD
  Bus Station
  
  7:05 AM
  
  Mendoza
  Bus Station
  
  0
  
  Premium Economy
  
  $32
  
  A Bus from Vía Tac goes from Bus Station, Córdoba, CD (Argentina) at 10/25/2026 8:30:00 PM to Bus Station, Mendoza (Argentina) arriving at 10/26/2026 7:05:00 AM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 10h 35m
Travel time is 5h 24m longer, but you will save $47

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Autotransportes San Juan	17h 20m	12:20 AM	Santiago del Estero	Central Bus Station	5:40 PM	Mendoza	Bus Station	Premium Economy	$99	A Bus from Autotransportes San Juan goes from Central Bus Station, Santiago del Estero (Argentina) at 10/30/2026 12:20:00 AM to Bus Station, Mendoza (Argentina) arriving at 10/30/2026 5:40:00 PM. 50 Premium Economy ticket for $99 per person are available. Travel duration is 17h 20m
Autotransportes San Juan	18h 45m	2:15 PM	Santiago del Estero	Central Bus Station	9:00 AM	Mendoza	Bus Station	Premium Economy	$99	A Bus from Autotransportes San Juan goes from Central Bus Station, Santiago del Estero (Argentina) at 10/30/2026 2:15:00 PM to Bus Station, Mendoza (Argentina) arriving at 10/31/2026 9:00:00 AM. 50 Premium Economy ticket for $99 per person are available. Travel duration is 18h 45m
Andesmar	17h 15m	5:15 PM	Santiago del Estero	Central Bus Station	10:30 AM	Mendoza	Bus Station	Premium Economy	$99	A Bus from Andesmar goes from Central Bus Station, Santiago del Estero (Argentina) at 10/30/2026 5:15:00 PM to Bus Station, Mendoza (Argentina) arriving at 10/31/2026 10:30:00 AM. 50 Premium Economy ticket for $99 per person are available. Travel duration is 17h 15m
20 de Junio	17h 45m	1:15 AM	Santiago del Estero	Central Bus Station	7:00 PM	Mendoza	Bus Station	Economy	$107	A Bus from 20 de Junio goes from Central Bus Station, Santiago del Estero (Argentina) at 10/30/2026 1:15:00 AM to Bus Station, Mendoza (Argentina) arriving at 10/30/2026 7:00:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 17h 45m
20 de Junio	17h 15m	6:40 AM	Santiago del Estero	Central Bus Station	11:55 PM	Mendoza	Bus Station	Premium Economy	$116	A Bus from 20 de Junio goes from Central Bus Station, Santiago del Estero (Argentina) at 10/30/2026 6:40:00 AM to Bus Station, Mendoza (Argentina) arriving at 10/30/2026 11:55:00 PM. 50 Premium Economy ticket for $116 per person are available. Travel duration is 17h 15m

Did you know that if you travel from Santiago del Estero to Mendoza via Córdoba, CD, you can save more than $47? You can find the corresponding connections below.
- Vía Tac
  
  22h 39m
  
  0
  
  8:26 AM
  
  Santiago del Estero
  Central Bus Station
  
  4:46 PM
  
  Córdoba, CD
  Bus Station
  
  0
  
  Premium Economy
  
  $20
  
  A Bus from Vía Tac goes from Central Bus Station, Santiago del Estero (Argentina) at 10/25/2026 8:26:00 AM to Bus Station, Córdoba, CD (Argentina) arriving at 10/25/2026 4:46:00 PM. 50 Premium Economy ticket for $20 per person are available. Travel duration is 8h 20m
- Vía Tac
  
  10h 35m
  
  0
  
  8:30 PM
  
  Córdoba, CD
  Bus Station
  
  7:05 AM
  
  Mendoza
  Bus Station
  
  0
  
  Premium Economy
  
  $32
  
  A Bus from Vía Tac goes from Bus Station, Córdoba, CD (Argentina) at 10/25/2026 8:30:00 PM to Bus Station, Mendoza (Argentina) arriving at 10/26/2026 7:05:00 AM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 10h 35m
Travel time is 5h 24m longer, but you will save $47

Best Price Offer: The price for the cheapest bus from Santiago del Estero to Mendoza is $99 on 10/24/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Santiago del Estero and Mendoza

See here how frequent the connections between Santiago del Estero and Mendoza are, during different times and days of the week.

Sunday is the busiest day, with more than 17 daily buses from Santiago del Estero to Mendoza. Saturday has instead the fewest connections, with only 8 daily coaches between Santiago del Estero and Mendoza.

The busiest time of the day is the Afternoon, with 54 buses from Santiago del Estero to Mendoza, while Night sees the fewest connections between Santiago del Estero and Mendoza, with 16 offers.

Facts about the bus from Santiago del Estero to Mendoza

Compare all providers like 20 de Junio, Andesmar and Autotransportes San Juan that travel 15 times every day by bus from Santiago del Estero to Mendoza in one click! Book your bus ticket from Santiago del Estero to Mendoza starting from $99!

Cheapest Bus	$99
Fastest Bus	17h 15m
Earliest Bus	6:40 AM
Latest Bus	5:15 PM
Daily Bus Routes	15 Ø
Distance	445.5 miles
Bus Companies	20 de Junio, Andesmar and Autotransportes San Juan

Cheapest bus connections from Santiago del Estero to Mendoza

Every day, 15 buses from 3 bus companies leave Santiago del Estero for Mendoza: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/24/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 10/18

Monday 10/19

Tuesday 10/20

Wednesday 10/21

Thursday 10/22

Friday 10/23

Saturday 10/24

$99

Sunday 10/25

$103

Monday 10/26

$103

Tuesday 10/27

$103

Wednesday 10/28

$103

Thursday 10/29

$103

Friday 10/30

$99

Saturday 10/31

$103

Sunday 11/01

Monday 11/02

$99

Tuesday 11/03

$103

Wednesday 11/04

$99

Thursday 11/05

$103

Friday 11/06

$103

Saturday 11/07

$103

Sunday 11/08

$103

Monday 11/09

$103

Tuesday 11/10

$103

Wednesday 11/11

$103

Thursday 11/12

$103

Friday 11/13

Saturday 11/14

The cheapest time to travel from Santiago del Estero to Mendoza

See here on which day and which time of the day you can find the cheapest bus ticket from Santiago del Estero to Mendoza, for the next 30 days.

With a price starting from $99, Sunday is the cheapest day for a bus from Santiago del Estero to Mendoza. Sunday instead is the most expensive day with prices starting from $99.

Afternoon is the cheapest day time for bus tickets from Santiago del Estero to Mendoza, with $99. Morning is the most expensive time of the day with prices starting from $103.

How to save money travelling from Santiago del Estero to Mendoza

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santiago del Estero to Mendoza in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santiago del Estero to Mendoza, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santiago del Estero to Mendoza are also emptier.

All bus stations and stops in Santiago del Estero and Mendoza

In the map below, you can see where to find all bus stations in Santiago del Estero and Mendoza.

Central Bus Station

Av. Roca Norte 100

Av. Libertad & Av. Aguirre

Ambargasta

El Saladillo

Regional Hospital "Dr. Ramón Carrillo"

Bus Station

Juan B. Alberdi s/n

Hotel Internacional

Av. Sarmiento 720

Hotel Hyatt

Chile 1124

Puente del Inca

Hotel Aconcagua

San Lorenzo 545

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Santiago del Estero to Mendoza? Compare all modes of transports from Santiago del Estero to Mendoza.

Service and Comfort on the bus from Santiago del Estero to Mendoza

Want to know which seat classes are available on the buses from Santiago del Estero to Mendoza? Or which bus companies serve the route Santiago del Estero to Mendoza? Below you will find answers to your questions.

FAQs about the Santiago del Estero to Mendoza bus

How much does a Santiago del Estero Mendoza bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $99 and takes 17h 15m to reach Mendoza. Compare offers to save money!

How much could I save by comparing buses from Santiago del Estero to Mendoza?

This route is offered by 3 companies with a range of ticket prices between $99 and $152. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Mendoza.

On average, how many connections are available from Santiago del Estero to Mendoza each day?

Every day, the Santiago del Estero to Mendoza bus route is served by approximately 15 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Santiago del Estero to Mendoza take?

The fastest bus from Santiago del Estero to Mendoza is offered by 20 de Junio and takes 17h 15m. Bus tickets for this connection cost $116. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Santiago del Estero to Mendoza?

The earliest bus arriving in Mendoza from Santiago del Estero starts at 6:40 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Santiago del Estero to Mendoza?

The latest bus trip departing from Santiago del Estero for Mendoza starts at 5:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Santiago del Estero Mendoza route?

When traveling by bus from Santiago del Estero to Mendoza, passengers can travel with 20 de Junio, Andesmar and Autotransportes San Juan. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Santiago del Estero and Mendoza?

You can check all the direct connections between Santiago del Estero and Mendoza by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: 20 de Junio, Andesmar and Autotransportes San Juan.

What can I take with me on the Santiago del Estero to Mendoza bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Santiago del Estero Mendoza bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Santiago del Estero Mendoza bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santiago del Estero to Mendoza on your planned travel date.

How does CheckMyBus find the best bus deals from Santiago del Estero to Mendoza?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 15 daily trips between Santiago del Estero and Mendoza. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Santiago del Estero to Mendoza?

Prices and availability for 15 trips between Santiago del Estero and Mendoza change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Santiago del Estero to Mendoza

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Santiago del Estero and to Mendoza

Here’s an overview of the most popular bus routes to Santiago del Estero and to Mendoza. Simply click on the connection of your choice, and you will find all the details about your bus route!