Which bus from San Francisco to Santa Ana, CA is the cheapest?

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Compare all timetables for the bus from San Francisco to Santa Ana, CA

Here is a selection of the cheapest bus trips from the schedule from San Francisco to Santa Ana, CA from various bus operators like Greyhound US or FlixBus for the next days.

today
$55
tomorrow
Saturday
Sunday
$70
Monday
Tuesday
$57
Wednesday
$63

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 14h 50m 7:10 AM San Francisco 5th/Townsend 10:00 PM Santa Ana, CA Bus Stop  Economy $55
Greyhound US 15h 30m 6:30 AM San Francisco Salesforce Transit Center 10:00 PM Santa Ana, CA Bus Stop  Economy $64
Greyhound US 11h 30m 10:30 PM San Francisco Salesforce Transit Center 10:00 AM Santa Ana, CA Bus Stop  Economy $110

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 15h 30m 6:30 AM San Francisco Salesforce Transit Center 10:00 PM Santa Ana, CA Bus Stop  Economy $70
Greyhound US 11h 30m 10:30 PM San Francisco Salesforce Transit Center 10:00 AM Santa Ana, CA Bus Stop  Economy $132
  • Did you know that if you travel from San Francisco to Santa Ana, CA via Los Angeles, you can save more than $19? You can find the corresponding connections below.
    • FlixBus
      11h 45m
      0
      10:15 AM
      San Francisco
      5th/Townsend
      5:10 PM
      Los Angeles
      University of California (curbside)
      0
      FlixBus
      Economy
      $44
      • Waiting Time 3h 10m
    • Greyhound US
      1h 40m
      0
      8:20 PM
      Los Angeles
      Union Station
      10:00 PM
      Santa Ana, CA
      Bus Stop
      0
      Greyhound US
      Economy
      $7
    Travel time is 0h 15m longer, but you will save $19

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 14h 50m 7:10 AM San Francisco 5th/Townsend 10:00 PM Santa Ana, CA Bus Stop  Economy $57
Greyhound US 15h 30m 6:30 AM San Francisco Salesforce Transit Center 10:00 PM Santa Ana, CA Bus Stop  Economy $67
Greyhound US 11h 30m 10:30 PM San Francisco Salesforce Transit Center 10:00 AM Santa Ana, CA Bus Stop  Economy $97
  • Did you know that if you travel from San Francisco to Santa Ana, CA via Los Angeles, you can save more than $6? You can find the corresponding connections below.
    • FlixBus
      11h 45m
      0
      10:15 AM
      San Francisco
      5th/Townsend
      5:10 PM
      Los Angeles
      University of California (curbside)
      0
      FlixBus
      Economy
      $44
      • Waiting Time 3h 10m
    • Greyhound US
      1h 40m
      0
      8:20 PM
      Los Angeles
      Union Station
      10:00 PM
      Santa Ana, CA
      Bus Stop
      0
      Greyhound US
      Economy
      $7
    Travel time is 0h 15m longer, but you will save $6

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 15h 30m 6:30 AM San Francisco Salesforce Transit Center 10:00 PM Santa Ana, CA Bus Stop  Economy $63
FlixBus 14h 50m 7:10 AM San Francisco 5th/Townsend 10:00 PM Santa Ana, CA Bus Stop  Economy $66
Greyhound US 11h 30m 10:30 PM San Francisco Salesforce Transit Center 10:00 AM Santa Ana, CA Bus Stop  Economy $154
  • Did you know that if you travel from San Francisco to Santa Ana, CA via Los Angeles, you can save more than $12? You can find the corresponding connections below.
    • FlixBus
      11h 45m
      0
      10:15 AM
      San Francisco
      5th/Townsend
      5:10 PM
      Los Angeles
      University of California (curbside)
      0
      FlixBus
      Economy
      $44
      • Waiting Time 3h 10m
    • Greyhound US
      1h 40m
      0
      8:20 PM
      Los Angeles
      Union Station
      10:00 PM
      Santa Ana, CA
      Bus Stop
      0
      Greyhound US
      Economy
      $7
    Travel time is 0h 15m longer, but you will save $12

Best Price Offer: The price for the cheapest bus from San Francisco to Santa Ana, CA is $39 on 8/26/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between San Francisco and Santa Ana, CA

See here how frequent the connections between San Francisco and Santa Ana, CA are, during different times and days of the week.
Tuesday is the busiest day, with more than 6 daily buses from San Francisco to Santa Ana, CA. Sunday has instead the fewest connections, with only 2 daily coaches between San Francisco and Santa Ana, CA.
The busiest time of the day is the Morning, with 9 buses from San Francisco to Santa Ana, CA, while Evening sees the fewest connections between San Francisco and Santa Ana, CA, with 5 offers.

Facts about the bus from San Francisco to Santa Ana, CA

Compare all providers like Greyhound US and FlixBus that travel 3 times every day by bus from San Francisco to Santa Ana, CA in one click! Book your bus ticket from San Francisco to Santa Ana, CA starting from $39!

Cheapest Bus $39
Fastest Bus 11h 30m
Earliest Bus 6:30 AM
Latest Bus 10:30 PM
Daily Bus Routes 3 Ø
Distance 376.9 miles
Bus Companies Greyhound US and FlixBus

Cheapest bus connections from San Francisco to Santa Ana, CA

Every day, 3 buses from 2 bus companies leave San Francisco for Santa Ana, CA: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 08/27/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 08/23
Monday 08/24
Tuesday 08/25
Wednesday 08/26
Thursday 08/27
$55
Friday 08/28
Saturday 08/29
Sunday 08/30
$70
Monday 08/31
Tuesday 09/01
$61
Wednesday 09/02
$63
Thursday 09/03
$83
Friday 09/04
$93
Saturday 09/05
$65
Sunday 09/06
Monday 09/07
$64
Tuesday 09/08
$62
Wednesday 09/09
Thursday 09/10
Friday 09/11
$78
Saturday 09/12
$70
Sunday 09/13
$75
Monday 09/14
$48
Tuesday 09/15
$47
Wednesday 09/16
$55
Thursday 09/17
$60
Friday 09/18
$79
Saturday 09/19

The cheapest time to travel from San Francisco to Santa Ana, CA

See here on which day and which time of the day you can find the cheapest bus ticket from San Francisco to Santa Ana, CA, for the next 30 days.
With a price starting from $47, Tuesday is the cheapest day for a bus from San Francisco to Santa Ana, CA. Sunday instead is the most expensive day with prices starting from $70.
Morning is the cheapest day time for bus tickets from San Francisco to Santa Ana, CA, with $55. Evening is the most expensive time of the day with prices starting from $97.

How to save money travelling from San Francisco to Santa Ana, CA

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Francisco to Santa Ana, CA in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Francisco to Santa Ana, CA, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Francisco to Santa Ana, CA are also emptier.

Beloved bus companies from San Francisco to Santa Ana, CA

These are the most booked bus companies between San Francisco to Santa Ana, CA from our users.

FlixBus from San Francisco to Santa Ana, CA

FlixBus

Here you will find the key facts about the FlixBus bus route San Francisco to Santa Ana, CA:

Cheapest Price $55
Fastest Bus 14h 50m
Earliest Bus 7:10 AM
Last Bus 7:10 AM
Daily Connections 1 Ø
Found on 8/2/2026

All bus stations and stops in San Francisco and Santa Ana, CA

In the map below, you can see where to find all bus stations in San Francisco and Santa Ana, CA.

Service and Comfort on the bus from San Francisco to Santa Ana, CA

Want to know which seat classes are available on the buses from San Francisco to Santa Ana, CA? Or which bus companies serve the route San Francisco to Santa Ana, CA? Below you will find answers to your questions.

FAQs about the San Francisco to Santa Ana, CA bus

How much does a San Francisco Santa Ana, CA bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $39 and takes 14h 50m to reach Santa Ana, CA. Compare offers to save money!

How much could I save by comparing buses from San Francisco to Santa Ana, CA?

This route is offered by 2 companies with a range of ticket prices between $39 and $154. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santa Ana, CA.

On average, how many connections are available from San Francisco to Santa Ana, CA each day?

Every day, the San Francisco to Santa Ana, CA bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Francisco to Santa Ana, CA take?

The fastest bus from San Francisco to Santa Ana, CA is offered by Greyhound US and takes 11h 30m. Bus tickets for this connection cost $110. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Francisco to Santa Ana, CA?

The earliest bus arriving in Santa Ana, CA from San Francisco starts at 6:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Francisco to Santa Ana, CA?

The latest bus trip departing from San Francisco for Santa Ana, CA starts at 10:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Francisco Santa Ana, CA route?

When traveling by bus from San Francisco to Santa Ana, CA, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Francisco and Santa Ana, CA?

You can check all the direct connections between San Francisco and Santa Ana, CA by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the San Francisco to Santa Ana, CA bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Francisco Santa Ana, CA bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Francisco Santa Ana, CA bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Francisco to Santa Ana, CA on your planned travel date.

How does CheckMyBus find the best bus deals from San Francisco to Santa Ana, CA?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between San Francisco and Santa Ana, CA. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Francisco to Santa Ana, CA?

Prices and availability for 3 trips between San Francisco and Santa Ana, CA change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Francisco to Santa Ana, CA

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Francisco and to Santa Ana, CA

Here’s an overview of the most popular bus routes to San Francisco and to Santa Ana, CA. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to San Francisco and to Santa Ana, CA
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