Bus San Francisco to Myrtle Beach, SC: Compare prices and save money

Compare all timetables for the bus from San Francisco to Myrtle Beach, SC

Here is a selection of the cheapest bus trips from the schedule from San Francisco to Myrtle Beach, SC from various bus operators like Greyhound US or FlixBus for the next days.

today

tomorrow

Sunday

Monday

$226

Tuesday

$222

Wednesday

$220

Thursday

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	71h 40m	1:10 PM	San Francisco	Bus Station Transbay	3:50 PM	Myrtle Beach, SC	Bus Stop	Economy	$226	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 10/26/2026 1:10:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 10/29/2026 3:50:00 PM. 50 Economy ticket for $226 per person are available. Travel duration is 71h 40m
FlixBus	76h 10m	8:40 AM	San Francisco	5th/Townsend	3:50 PM	Myrtle Beach, SC	Bus Stop	Economy	$233	A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 10/26/2026 8:40:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 10/29/2026 3:50:00 PM. 50 Economy ticket for $233 per person are available. Travel duration is 76h 10m
Greyhound US	86h 20m	10:30 PM	San Francisco	Bus Station Transbay	3:50 PM	Myrtle Beach, SC	Bus Stop	Economy	$262	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 10/26/2026 10:30:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 10/30/2026 3:50:00 PM. 50 Economy ticket for $262 per person are available. Travel duration is 86h 20m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	71h 40m	1:10 PM	San Francisco	Bus Station Transbay	3:50 PM	Myrtle Beach, SC	Bus Stop	Economy	$222	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 10/27/2026 1:10:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 10/30/2026 3:50:00 PM. 50 Economy ticket for $222 per person are available. Travel duration is 71h 40m
FlixBus	76h 10m	8:40 AM	San Francisco	5th/Townsend	3:50 PM	Myrtle Beach, SC	Bus Stop	Economy	$226	A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 10/27/2026 8:40:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 10/30/2026 3:50:00 PM. 50 Economy ticket for $226 per person are available. Travel duration is 76h 10m
Greyhound US	86h 20m	10:30 PM	San Francisco	Bus Station Transbay	3:50 PM	Myrtle Beach, SC	Bus Stop	Economy	$241	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 10/27/2026 10:30:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 10/31/2026 3:50:00 PM. 50 Economy ticket for $241 per person are available. Travel duration is 86h 20m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	71h 40m	1:10 PM	San Francisco	Bus Station Transbay	3:50 PM	Myrtle Beach, SC	Bus Stop	Economy	$220	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 10/28/2026 1:10:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 10/31/2026 3:50:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 71h 40m
FlixBus	76h 10m	8:40 AM	San Francisco	5th/Townsend	3:50 PM	Myrtle Beach, SC	Bus Stop	Economy	$240	A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 10/28/2026 8:40:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 10/31/2026 3:50:00 PM. 50 Economy ticket for $240 per person are available. Travel duration is 76h 10m
Greyhound US	87h 20m	10:30 PM	San Francisco	Bus Station Transbay	3:50 PM	Myrtle Beach, SC	Bus Stop	Economy	$288	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 10/28/2026 10:30:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/1/2026 3:50:00 PM. 50 Economy ticket for $288 per person are available. Travel duration is 87h 20m

Best Price Offer: The price for the cheapest bus from San Francisco to Myrtle Beach, SC is $213 on 11/12/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between San Francisco and Myrtle Beach, SC

See here how frequent the connections between San Francisco and Myrtle Beach, SC are, during different times and days of the week.

Monday is the busiest day, with more than 3 daily buses from San Francisco to Myrtle Beach, SC. Monday has instead the fewest connections, with only 3 daily coaches between San Francisco and Myrtle Beach, SC.

The busiest time of the day is the Morning, with 3 buses from San Francisco to Myrtle Beach, SC, while Morning sees the fewest connections between San Francisco and Myrtle Beach, SC, with 3 offers.

Facts about the bus from San Francisco to Myrtle Beach, SC

Compare all providers like Greyhound US and FlixBus that travel 3 times every day by bus from San Francisco to Myrtle Beach, SC in one click! Book your bus ticket from San Francisco to Myrtle Beach, SC starting from $213!

Cheapest Bus	$213
Fastest Bus	74h 40m
Earliest Bus	8:40 AM
Latest Bus	10:30 PM
Daily Bus Routes	3 Ø
Distance	2,435.5 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from San Francisco to Myrtle Beach, SC

Every day, 3 buses from 2 bus companies leave San Francisco for Myrtle Beach, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/23/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 10/18

Monday 10/19

Tuesday 10/20

Wednesday 10/21

Thursday 10/22

Friday 10/23

Saturday 10/24

Sunday 10/25

Monday 10/26

$226

Tuesday 10/27

$222

Wednesday 10/28

$220

Thursday 10/29

Friday 10/30

Saturday 10/31

Sunday 11/01

Monday 11/02

$214

Tuesday 11/03

Wednesday 11/04

Thursday 11/05

$214

Friday 11/06

Saturday 11/07

Sunday 11/08

$214

Monday 11/09

$214

Tuesday 11/10

$214

Wednesday 11/11

Thursday 11/12

$213

Friday 11/13

Saturday 11/14

The cheapest time to travel from San Francisco to Myrtle Beach, SC

See here on which day and which time of the day you can find the cheapest bus ticket from San Francisco to Myrtle Beach, SC, for the next 30 days.

With a price starting from $214, Monday is the cheapest day for a bus from San Francisco to Myrtle Beach, SC. Wednesday instead is the most expensive day with prices starting from $217.

Afternoon is the cheapest day time for bus tickets from San Francisco to Myrtle Beach, SC, with $220. Evening is the most expensive time of the day with prices starting from $241.

How to save money travelling from San Francisco to Myrtle Beach, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Francisco to Myrtle Beach, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Francisco to Myrtle Beach, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Francisco to Myrtle Beach, SC are also emptier.

All bus stations and stops in San Francisco and Myrtle Beach, SC

In the map below, you can see where to find all bus stations in San Francisco and Myrtle Beach, SC.

5th/Townsend

Townsend St 400

Union Square

Post St 470

Bus Station Transbay

Folsom Street 200

One Ferry Building

Passenger Loading Zone in front of Ferry Building on Embarcadero. Bus will stop near Marketbar Cafe.

Beach St & Hyde St

Bus Stop

7th Ave N 511

Service and Comfort on the bus from San Francisco to Myrtle Beach, SC

Want to know which seat classes are available on the buses from San Francisco to Myrtle Beach, SC? Or which bus companies serve the route San Francisco to Myrtle Beach, SC? Below you will find answers to your questions.

FAQs about the San Francisco to Myrtle Beach, SC bus

How much does a San Francisco Myrtle Beach, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $213 and takes 74h 40m to reach Myrtle Beach, SC. Compare offers to save money!

How much could I save by comparing buses from San Francisco to Myrtle Beach, SC?

This route is offered by 2 companies with a range of ticket prices between $213 and $288. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Myrtle Beach, SC.

On average, how many connections are available from San Francisco to Myrtle Beach, SC each day?

Every day, the San Francisco to Myrtle Beach, SC bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Francisco to Myrtle Beach, SC take?

The fastest bus from San Francisco to Myrtle Beach, SC is offered by Greyhound US and takes 74h 40m. Bus tickets for this connection cost $226. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Francisco to Myrtle Beach, SC?

The earliest bus arriving in Myrtle Beach, SC from San Francisco starts at 8:40 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Francisco to Myrtle Beach, SC?

The latest bus trip departing from San Francisco for Myrtle Beach, SC starts at 10:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Francisco Myrtle Beach, SC route?

When traveling by bus from San Francisco to Myrtle Beach, SC, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Francisco and Myrtle Beach, SC?

You can check all the direct connections between San Francisco and Myrtle Beach, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the San Francisco to Myrtle Beach, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Francisco Myrtle Beach, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Francisco Myrtle Beach, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Francisco to Myrtle Beach, SC on your planned travel date.

How does CheckMyBus find the best bus deals from San Francisco to Myrtle Beach, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between San Francisco and Myrtle Beach, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Francisco to Myrtle Beach, SC?

Prices and availability for 3 trips between San Francisco and Myrtle Beach, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Francisco to Myrtle Beach, SC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Francisco and to Myrtle Beach, SC

Here’s an overview of the most popular bus routes to San Francisco and to Myrtle Beach, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!