Compare all timetables for the bus from San Francisco to Indianapolis
Here is a selection of the cheapest bus trips from the schedule from San Francisco to Indianapolis from various bus operators like Greyhound US or FlixBus for the next days.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 55h 5m | 1:10 PM | San Francisco | Bus Station Transbay | 11:15 PM | Indianapolis | Washington / Delaware | Economy | $159 |
A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 10/24/2026 1:10:00 PM to Washington / Delaware, Indianapolis (USA) arriving at 10/26/2026 11:15:00 PM. 50 Economy ticket for $159 per person are available. Travel duration is 55h 5m
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| Greyhound US | 51h 20m | 1:10 PM | San Francisco | Bus Station Transbay | 7:30 PM | Indianapolis | Central Bus Station | Economy | $160 |
A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 10/24/2026 1:10:00 PM to Central Bus Station, Indianapolis (USA) arriving at 10/26/2026 7:30:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 51h 20m
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| FlixBus | 59h 35m | 8:40 AM | San Francisco | 5th/Townsend | 11:15 PM | Indianapolis | Washington / Delaware | Economy | $161 |
A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 10/24/2026 8:40:00 AM to Washington / Delaware, Indianapolis (USA) arriving at 10/26/2026 11:15:00 PM. 50 Economy ticket for $161 per person are available. Travel duration is 59h 35m
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| FlixBus | 55h 50m | 8:40 AM | San Francisco | 5th/Townsend | 7:30 PM | Indianapolis | Central Bus Station | Economy | $162 |
A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 10/24/2026 8:40:00 AM to Central Bus Station, Indianapolis (USA) arriving at 10/26/2026 7:30:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 55h 50m
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| FlixBus | 58h 25m | 1:05 AM | San Francisco | 5th/Townsend | 2:30 PM | Indianapolis | Central Bus Station | Economy | $180 |
A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 10/24/2026 1:05:00 AM to Central Bus Station, Indianapolis (USA) arriving at 10/26/2026 2:30:00 PM. 50 Economy ticket for $180 per person are available. Travel duration is 58h 25m
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Best Price Offer: The price for the cheapest bus from San Francisco to Indianapolis is $133 on 11/5/2026. Flexible travelers save on ticket prices.
Facts about the bus from San Francisco to Indianapolis
Compare all providers like Greyhound US and FlixBus that travel 7 times every day by bus from San Francisco to Indianapolis in one click! Book your bus ticket from San Francisco to Indianapolis starting from $133!
| Cheapest Bus | $133 |
| Fastest Bus | 54h 20m |
| Earliest Bus | 1:05 AM |
| Latest Bus | 10:30 PM |
| Daily Bus Routes | 7 Ø |
| Distance | 1,944.5 miles |
| Bus Companies | Greyhound US and FlixBus |
Cheapest bus connections from San Francisco to Indianapolis
Every day, 7 buses from 2 bus companies leave San Francisco for Indianapolis: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/22/2026 and for the following days.
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
10/18
Monday
10/19
Tuesday
10/20
Wednesday
10/21
Thursday
10/22
Friday
10/23
Saturday
10/24
$159
Sunday
10/25
Monday
10/26
Tuesday
10/27
Wednesday
10/28
Thursday
10/29
Friday
10/30
$180
Saturday
10/31
$167
Sunday
11/01
Monday
11/02
Tuesday
11/03
Wednesday
11/04
$167
Thursday
11/05
$133
Friday
11/06
Saturday
11/07
$148
Sunday
11/08
Monday
11/09
$165
Tuesday
11/10
Wednesday
11/11
$138
Thursday
11/12
Friday
11/13
Saturday
11/14
How to save money travelling from San Francisco to Indianapolis
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:
Book the ticket from San Francisco to Indianapolis in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Francisco to Indianapolis, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Francisco to Indianapolis are also emptier.Beloved bus companies from San Francisco to Indianapolis
These are the most booked bus companies between San Francisco to Indianapolis from our users.
FlixBus from San Francisco to Indianapolis
Here you will find the key facts about the FlixBus bus route San Francisco to Indianapolis:
| Cheapest Price | $161 |
| Fastest Bus | 58h 50m |
| Earliest Bus | 1:05 AM |
| Last Bus | 8:40 AM |
| Daily Connections | 3 Ø |
| Found on | 9/24/2026 |
All bus stations and stops in San Francisco and Indianapolis
In the map below, you can see where to find all bus stations in San Francisco and Indianapolis.
Service and Comfort on the bus from San Francisco to Indianapolis
Want to know which seat classes are available on the buses from San Francisco to Indianapolis? Or which bus companies serve the route San Francisco to Indianapolis? Below you will find answers to your questions.
FAQs about the San Francisco to Indianapolis bus
How much does a San Francisco Indianapolis bus trip cost?
This depends on, among other things, the day and time of travel. The cheapest trip is available from $133 and takes 58h 5m to reach Indianapolis. Compare offers to save money!
How much could I save by comparing buses from San Francisco to Indianapolis?
This route is offered by 2 companies with a range of ticket prices between $133 and $204. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Indianapolis.
On average, how many connections are available from San Francisco to Indianapolis each day?
Every day, the San Francisco to Indianapolis bus route is served by approximately 7 connections. With our search, you can compare bus times to find the perfect trip.
How long does a bus journey from San Francisco to Indianapolis take?
The fastest bus from San Francisco to Indianapolis is offered by Greyhound US and takes 54h 20m. Bus tickets for this connection cost $160. In this context, bear in mind that the journey can take longer due to traffic.
What time is the first bus from San Francisco to Indianapolis?
The earliest bus arriving in Indianapolis from San Francisco starts at 1:05 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.
What time is the last bus from San Francisco to Indianapolis?
The latest bus trip departing from San Francisco for Indianapolis starts at 10:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.
Which bus companies operate the San Francisco Indianapolis route?
When traveling by bus from San Francisco to Indianapolis, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.
Is there a direct bus between San Francisco and Indianapolis?
You can check all the direct connections between San Francisco and Indianapolis by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.
What can I take with me on the San Francisco to Indianapolis bus route?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Francisco Indianapolis bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.
What equipment is available for the San Francisco Indianapolis bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Francisco to Indianapolis on your planned travel date.
How does CheckMyBus find the best bus deals from San Francisco to Indianapolis?
CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 7 daily trips between San Francisco and Indianapolis. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.
How does CheckMyBus technology work for trips from San Francisco to Indianapolis?
Prices and availability for 7 trips between San Francisco and Indianapolis change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.
Available seat classes which are offered on the bus route San Francisco to Indianapolis
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to San Francisco and to Indianapolis
Here’s an overview of the most popular bus routes to San Francisco and to Indianapolis. Simply click on the connection of your choice, and you will find all the details about your bus route!
- Bus Routes to San Francisco
- Buses Anaheim, CA - San Francisco
- Bus from Chicago to San Francisco
- Bus Denver - San Francisco
- Buses El Centro, CA - San Francisco
- Glendale, CA to San Francisco bus
- Bus Huntington Park, CA - San Francisco
- Bus to San Francisco from Katy, TX
- Bus Las Vegas - San Francisco
- Bus from Los Angeles to San Francisco
- Bus to San Francisco from Monterey, CA
- Bus Redding, CA to San Francisco
- Buses to San Francisco from Reno, NV
- Buses from Riverside, CA to San Francisco
- Bus to San Francisco from Sacramento
- Bus San Diego to San Francisco
- From San Fernando, CA to San Francisco bus
- From San Jose, CA to San Francisco bus
- Bus Santa Barbara, CA - San Francisco
- Buses Seattle, WA - San Francisco
- Buses Tucson, AZ to San Francisco
- Bus Routes to Indianapolis
- Bus from Atlanta, GA to Indianapolis
- Bus to Indianapolis from Baton Rouge
- Bus from Cincinnati to Indianapolis
- Bus Columbus, OH to Indianapolis
- Bus Del Rio, TX - Indianapolis
- Bus from Fort Myers, FL to Indianapolis
- Fort Wayne, IN to Indianapolis bus
- Bus from Joplin, MO to Indianapolis
- Bus from Lafayette, IN to Indianapolis
- Bus from Louisville, KY to Indianapolis
- Buses from Monterrey, NL to Indianapolis
- From Nashville to Indianapolis bus
- Buses New Orleans, LA - Indianapolis
- New York to Indianapolis bus
- Buses from Orlando, FL to Indianapolis
- Bus Richmond, VA - Indianapolis
- Bus San Antonio, TX to Indianapolis
- From St. Louis, MO to Indianapolis bus
- Bus to Indianapolis from Toledo, OH
- Buses Tucson, AZ - Indianapolis
Popular Airport Shuttles to San Francisco and to Indianapolis
