Bus Salisbury, NC to Buffalo, NY: Compare prices and save money

Compare all timetables for the bus from Salisbury, NC to Buffalo, NY

Here is a selection of the cheapest bus trips from the schedule from Salisbury, NC to Buffalo, NY from various bus operators like Greyhound US for the next days.

today

$109

tomorrow

$101

Sunday

$108

Monday

$93

Tuesday

$102

Wednesday

$104

Thursday

$104

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	28h 5m	11:00 AM	Salisbury, NC	Greyhound bus station	3:05 PM	Buffalo, NY	Central Bus Station	Economy	$109	A Bus from Greyhound US goes from Greyhound bus station, Salisbury, NC (USA) at 10/23/2026 11:00:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 10/24/2026 3:05:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 28h 5m
Greyhound US	23h 35m	7:15 PM	Salisbury, NC	Greyhound bus station	6:50 PM	Buffalo, NY	Central Bus Station	Economy	$120	A Bus from Greyhound US goes from Greyhound bus station, Salisbury, NC (USA) at 10/23/2026 7:15:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 10/24/2026 6:50:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 23h 35m
Greyhound US	25h 20m	6:10 AM	Salisbury, NC	Greyhound bus station	7:30 AM	Buffalo, NY	Central Bus Station	Economy	$121	A Bus from Greyhound US goes from Greyhound bus station, Salisbury, NC (USA) at 10/23/2026 6:10:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 10/24/2026 7:30:00 AM. 50 Economy ticket for $121 per person are available. Travel duration is 25h 20m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	23h 35m	7:15 PM	Salisbury, NC	Greyhound bus station	6:50 PM	Buffalo, NY	Central Bus Station	Economy	$101	A Bus from Greyhound US goes from Greyhound bus station, Salisbury, NC (USA) at 10/24/2026 7:15:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 10/25/2026 6:50:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 23h 35m
Greyhound US	28h 5m	11:00 AM	Salisbury, NC	Greyhound bus station	3:05 PM	Buffalo, NY	Central Bus Station	Economy	$102	A Bus from Greyhound US goes from Greyhound bus station, Salisbury, NC (USA) at 10/24/2026 11:00:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 10/25/2026 3:05:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 28h 5m
Greyhound US	25h 20m	6:10 AM	Salisbury, NC	Greyhound bus station	7:30 AM	Buffalo, NY	Central Bus Station	Economy	$118	A Bus from Greyhound US goes from Greyhound bus station, Salisbury, NC (USA) at 10/24/2026 6:10:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 10/25/2026 7:30:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 25h 20m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	28h 5m	11:00 AM	Salisbury, NC	Greyhound bus station	3:05 PM	Buffalo, NY	Central Bus Station	Economy	$108	A Bus from Greyhound US goes from Greyhound bus station, Salisbury, NC (USA) at 10/25/2026 11:00:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 10/26/2026 3:05:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 28h 5m
Greyhound US	23h 35m	7:15 PM	Salisbury, NC	Greyhound bus station	6:50 PM	Buffalo, NY	Central Bus Station	Economy	$108	A Bus from Greyhound US goes from Greyhound bus station, Salisbury, NC (USA) at 10/25/2026 7:15:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 10/26/2026 6:50:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 23h 35m
Greyhound US	25h 20m	6:10 AM	Salisbury, NC	Greyhound bus station	7:30 AM	Buffalo, NY	Central Bus Station	Economy	$135	A Bus from Greyhound US goes from Greyhound bus station, Salisbury, NC (USA) at 10/25/2026 6:10:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 10/26/2026 7:30:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 25h 20m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	28h 5m	11:00 AM	Salisbury, NC	Greyhound bus station	3:05 PM	Buffalo, NY	Central Bus Station	Economy	$93	A Bus from Greyhound US goes from Greyhound bus station, Salisbury, NC (USA) at 10/26/2026 11:00:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 10/27/2026 3:05:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 28h 5m
Greyhound US	25h 20m	7:15 PM	Salisbury, NC	Greyhound bus station	8:35 PM	Buffalo, NY	Central Bus Station	Economy	$94	A Bus from Greyhound US goes from Greyhound bus station, Salisbury, NC (USA) at 10/26/2026 7:15:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 10/27/2026 8:35:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 25h 20m
Greyhound US	25h 20m	6:10 AM	Salisbury, NC	Greyhound bus station	7:30 AM	Buffalo, NY	Central Bus Station	Economy	$122	A Bus from Greyhound US goes from Greyhound bus station, Salisbury, NC (USA) at 10/26/2026 6:10:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 10/27/2026 7:30:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 25h 20m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	28h 5m	11:00 AM	Salisbury, NC	Greyhound bus station	3:05 PM	Buffalo, NY	Central Bus Station	Economy	$102	A Bus from Greyhound US goes from Greyhound bus station, Salisbury, NC (USA) at 10/27/2026 11:00:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 10/28/2026 3:05:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 28h 5m
Greyhound US	23h 35m	7:15 PM	Salisbury, NC	Greyhound bus station	6:50 PM	Buffalo, NY	Central Bus Station	Economy	$103	A Bus from Greyhound US goes from Greyhound bus station, Salisbury, NC (USA) at 10/27/2026 7:15:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 10/28/2026 6:50:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 23h 35m
Greyhound US	25h 20m	6:10 AM	Salisbury, NC	Greyhound bus station	7:30 AM	Buffalo, NY	Central Bus Station	Economy	$112	A Bus from Greyhound US goes from Greyhound bus station, Salisbury, NC (USA) at 10/27/2026 6:10:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 10/28/2026 7:30:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 25h 20m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	28h 5m	11:00 AM	Salisbury, NC	Greyhound bus station	3:05 PM	Buffalo, NY	Central Bus Station	Economy	$104	A Bus from Greyhound US goes from Greyhound bus station, Salisbury, NC (USA) at 10/28/2026 11:00:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 10/29/2026 3:05:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 28h 5m
Greyhound US	23h 35m	7:15 PM	Salisbury, NC	Greyhound bus station	6:50 PM	Buffalo, NY	Central Bus Station	Economy	$106	A Bus from Greyhound US goes from Greyhound bus station, Salisbury, NC (USA) at 10/28/2026 7:15:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 10/29/2026 6:50:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 23h 35m
Greyhound US	25h 20m	6:10 AM	Salisbury, NC	Greyhound bus station	7:30 AM	Buffalo, NY	Central Bus Station	Economy	$110	A Bus from Greyhound US goes from Greyhound bus station, Salisbury, NC (USA) at 10/28/2026 6:10:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 10/29/2026 7:30:00 AM. 50 Economy ticket for $110 per person are available. Travel duration is 25h 20m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	28h 5m	11:00 AM	Salisbury, NC	Greyhound bus station	3:05 PM	Buffalo, NY	Central Bus Station	Economy	$104	A Bus from Greyhound US goes from Greyhound bus station, Salisbury, NC (USA) at 10/29/2026 11:00:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 10/30/2026 3:05:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 28h 5m
Greyhound US	23h 35m	7:15 PM	Salisbury, NC	Greyhound bus station	6:50 PM	Buffalo, NY	Central Bus Station	Economy	$109	A Bus from Greyhound US goes from Greyhound bus station, Salisbury, NC (USA) at 10/29/2026 7:15:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 10/30/2026 6:50:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 23h 35m
Greyhound US	25h 20m	6:10 AM	Salisbury, NC	Greyhound bus station	7:30 AM	Buffalo, NY	Central Bus Station	Economy	$117	A Bus from Greyhound US goes from Greyhound bus station, Salisbury, NC (USA) at 10/29/2026 6:10:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 10/30/2026 7:30:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 25h 20m

Best Price Offer: The price for the cheapest bus from Salisbury, NC to Buffalo, NY is $79 on 11/6/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Salisbury, NC and Buffalo, NY

See here how frequent the connections between Salisbury, NC and Buffalo, NY are, during different times and days of the week.

Monday is the busiest day, with more than 6 daily buses from Salisbury, NC to Buffalo, NY. Sunday has instead the fewest connections, with only 3 daily coaches between Salisbury, NC and Buffalo, NY.

The busiest time of the day is the Morning, with 20 buses from Salisbury, NC to Buffalo, NY, while Evening sees the fewest connections between Salisbury, NC and Buffalo, NY, with 10 offers.

Facts about the bus from Salisbury, NC to Buffalo, NY

Compare all providers like Greyhound US that travel 4 times every day by bus from Salisbury, NC to Buffalo, NY in one click! Book your bus ticket from Salisbury, NC to Buffalo, NY starting from $79!

Cheapest Bus	$79
Fastest Bus	23h 35m
Earliest Bus	6:10 AM
Latest Bus	7:15 PM
Daily Bus Routes	4 Ø
Distance	505.7 miles
Bus Companies	Greyhound US

Cheapest bus connections from Salisbury, NC to Buffalo, NY

Every day, 4 buses from 1 bus companies leave Salisbury, NC for Buffalo, NY: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/23/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 10/18

Monday 10/19

Tuesday 10/20

Wednesday 10/21

Thursday 10/22

Friday 10/23

$109

Saturday 10/24

$101

Sunday 10/25

$108

Monday 10/26

$97

Tuesday 10/27

$102

Wednesday 10/28

$108

Thursday 10/29

$108

Friday 10/30

$104

Saturday 10/31

$108

Sunday 11/01

Monday 11/02

$98

Tuesday 11/03

$98

Wednesday 11/04

$107

Thursday 11/05

$83

Friday 11/06

$79

Saturday 11/07

$81

Sunday 11/08

$87

Monday 11/09

$96

Tuesday 11/10

$90

Wednesday 11/11

$88

Thursday 11/12

$87

Friday 11/13

Saturday 11/14

The cheapest time to travel from Salisbury, NC to Buffalo, NY

See here on which day and which time of the day you can find the cheapest bus ticket from Salisbury, NC to Buffalo, NY, for the next 30 days.

With a price starting from $79, Friday is the cheapest day for a bus from Salisbury, NC to Buffalo, NY. Monday instead is the most expensive day with prices starting from $93.

Morning is the cheapest day time for bus tickets from Salisbury, NC to Buffalo, NY, with $93. Evening is the most expensive time of the day with prices starting from $94.

How to save money travelling from Salisbury, NC to Buffalo, NY

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Salisbury, NC to Buffalo, NY in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Salisbury, NC to Buffalo, NY, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Salisbury, NC to Buffalo, NY are also emptier.

All bus stations and stops in Salisbury, NC and Buffalo, NY

In the map below, you can see where to find all bus stations in Salisbury, NC and Buffalo, NY.

Greyhound bus station

Andrews St 100

Stokes Ferry Rd

Stokes Ferry Rd 1510

La Alcancia

S Main St 3023

South Salisbury Blvd

South Salisbury Blvd 1147

Central Bus Station

Ellicott Street 181

MTC / Downtown Terminal

Ellicott Street 181

Maple Road Gulf

Maple Rd 4641

Cleveland Hall

Asia Food Market

Niagara Falls Blvd 2055

Service and Comfort on the bus from Salisbury, NC to Buffalo, NY

Want to know which seat classes are available on the buses from Salisbury, NC to Buffalo, NY? Or which bus companies serve the route Salisbury, NC to Buffalo, NY? Below you will find answers to your questions.

FAQs about the Salisbury, NC to Buffalo, NY bus

How much does a Salisbury, NC Buffalo, NY bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $79 and takes 28h 5m to reach Buffalo, NY. Compare offers to save money!

How much could I save by comparing buses from Salisbury, NC to Buffalo, NY?

This route is offered by 1 companies with a range of ticket prices between $79 and $135. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Buffalo, NY.

On average, how many connections are available from Salisbury, NC to Buffalo, NY each day?

Every day, the Salisbury, NC to Buffalo, NY bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Salisbury, NC to Buffalo, NY take?

The fastest bus from Salisbury, NC to Buffalo, NY is offered by Greyhound US and takes 23h 35m. Bus tickets for this connection cost $120. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Salisbury, NC to Buffalo, NY?

The earliest bus arriving in Buffalo, NY from Salisbury, NC starts at 6:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Salisbury, NC to Buffalo, NY?

The latest bus trip departing from Salisbury, NC for Buffalo, NY starts at 7:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Salisbury, NC Buffalo, NY route?

When traveling by bus from Salisbury, NC to Buffalo, NY, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Salisbury, NC and Buffalo, NY?

You can check all the direct connections between Salisbury, NC and Buffalo, NY by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Salisbury, NC to Buffalo, NY bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Salisbury, NC Buffalo, NY bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Salisbury, NC Buffalo, NY bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Salisbury, NC to Buffalo, NY on your planned travel date.

How does CheckMyBus find the best bus deals from Salisbury, NC to Buffalo, NY?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 4 daily trips between Salisbury, NC and Buffalo, NY. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Salisbury, NC to Buffalo, NY?

Prices and availability for 4 trips between Salisbury, NC and Buffalo, NY change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Salisbury, NC to Buffalo, NY

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Salisbury, NC and to Buffalo, NY

Here’s an overview of the most popular bus routes to Salisbury, NC and to Buffalo, NY. Simply click on the connection of your choice, and you will find all the details about your bus route!