Bus from Rome to Lyon from $35

Compare all the bus companies and find the best price with CheckMyBus
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Rome to Lyon

Here is a selection of the cheapest bus trips from the schedule from Rome to Lyon from various bus operators like FlixBus, Itabus or BlaBlaCar Bus for the next days.

today
$47
tomorrow
$58
Friday
$58
Saturday
$70
Sunday
$58
Monday
$50
Tuesday
$41

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 14h 30m 7:00 AM Rome Tiburtina Bus Station 9:30 PM Lyon Perrache Bus Stop  Premium Economy $47
BlaBlaCar Bus 14h 45m 3:20 PM Rome Tiburtina Bus Station 6:05 AM Lyon Perrache Train Station  Economy $70
Itabus 15h 15m 9:45 PM Rome Tiburtina Bus Station 1:00 PM Lyon Perrache Bus Stop  Premium Economy $93
FlixBus 15h 20m 5:25 PM Rome Anagnina Bus Station 8:45 AM Lyon Lyon Avenue Tony Garnier Bus Stop  Economy $101
FlixBus 16h 50m 1:20 AM Rome Tiburtina Bus Station 6:10 PM Lyon Lyon Avenue Tony Garnier Bus Stop  Economy $114

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 14h 30m 7:00 AM Rome Tiburtina Bus Station 9:30 PM Lyon Perrache Bus Stop  Premium Economy $58
BlaBlaCar Bus 14h 45m 3:20 PM Rome Tiburtina Bus Station 6:05 AM Lyon Perrache Train Station  Economy $70
Itabus 15h 55m 1:00 PM Rome Tiburtina Bus Station 4:55 AM Lyon Perrache Bus Stop  Economy $78
FlixBus 16h 15m 9:55 PM Rome Tiburtina Bus Station 2:10 PM Lyon Lyon Avenue Tony Garnier Bus Stop  Economy $104
FlixBus 14h 55m 8:50 AM Rome Tiburtina Bus Station 11:45 PM Lyon Lyon Avenue Tony Garnier Bus Stop  Economy $112

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 14h 30m 7:00 AM Rome Tiburtina Bus Station 9:30 PM Lyon Perrache Bus Stop  Premium Economy $58
Itabus 16h 25m 8:00 AM Rome Tiburtina Bus Station 12:25 AM Lyon Perrache Bus Stop  Premium Economy $82
BlaBlaCar Bus 14h 45m 3:20 PM Rome Tiburtina Bus Station 6:05 AM Lyon Perrache Train Station  Economy $93
FlixBus 16h 15m 9:55 PM Rome Tiburtina Bus Station 2:10 PM Lyon Lyon Avenue Tony Garnier Bus Stop  Economy $94
FlixBus 16h 50m 1:20 AM Rome Tiburtina Bus Station 6:10 PM Lyon Lyon Avenue Tony Garnier Bus Stop  Economy $98

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 14h 30m 7:00 AM Rome Tiburtina Bus Station 9:30 PM Lyon Perrache Bus Stop  Premium Economy $70
Itabus 15h 55m 1:00 PM Rome Tiburtina Bus Station 4:55 AM Lyon Perrache Bus Stop  Premium Economy $82
BlaBlaCar Bus 14h 45m 3:20 PM Rome Tiburtina Bus Station 6:05 AM Lyon Perrache Train Station  Economy $82
FlixBus 16h 15m 9:55 PM Rome Tiburtina Bus Station 2:10 PM Lyon Lyon Avenue Tony Garnier Bus Stop  Economy $91
FlixBus 14h 50m 1:05 PM Rome Anagnina Bus Station 3:55 AM Lyon Lyon Avenue Tony Garnier Bus Stop  Economy $97
  • Did you know that if you travel from Rome to Lyon via Chambery, you can save more than $15? You can find the corresponding connections below.
    • Itabus
      17h 20m
      0
      7:00 AM
      Rome
      Tiburtina Bus Station
      8:00 PM
      Chambery
      Bus Station
      0
      Itabus
      Premium Economy
      $47
      • Waiting Time 2h 25m
    • FlixBus
      1h 55m
      0
      10:25 PM
      Chambery
      Bus Station
      12:20 AM
      Lyon
      Lyon Avenue Tony Garnier Bus Stop
      0
      FlixBus
      Economy
      $9
    Travel time is 2h 50m longer, but you will save $15

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 14h 30m 7:00 AM Rome Tiburtina Bus Station 9:30 PM Lyon Perrache Bus Stop  Premium Economy $58
Itabus 16h 25m 8:00 AM Rome Tiburtina Bus Station 12:25 AM Lyon Perrache Bus Stop  Premium Economy $73
BlaBlaCar Bus 14h 45m 3:20 PM Rome Tiburtina Bus Station 6:05 AM Lyon Perrache Train Station  Economy $82
FlixBus 14h 55m 7:45 AM Rome Tiburtina Bus Station 10:40 PM Lyon Lyon Avenue Tony Garnier Bus Stop  Economy $96
FlixBus 16h 15m 9:55 PM Rome Tiburtina Bus Station 2:10 PM Lyon Lyon Avenue Tony Garnier Bus Stop  Economy $97

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 15h 55m 1:00 PM Rome Tiburtina Bus Station 4:55 AM Lyon Perrache Bus Stop  Premium Economy $50
Itabus 16h 25m 8:00 AM Rome Tiburtina Bus Station 12:25 AM Lyon Perrache Bus Stop  Premium Economy $63
Itabus 14h 30m 7:00 AM Rome Tiburtina Bus Station 9:30 PM Lyon Perrache Bus Stop  Premium Economy $82
FlixBus 15h 20m 5:25 PM Rome Anagnina Bus Station 8:45 AM Lyon Lyon Avenue Tony Garnier Bus Stop  Economy $83
FlixBus 14h 55m 7:45 AM Rome Tiburtina Bus Station 10:40 PM Lyon Lyon Avenue Tony Garnier Bus Stop  Economy $90

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 16h 25m 8:00 AM Rome Tiburtina Bus Station 12:25 AM Lyon Perrache Bus Stop  Premium Economy $41
Itabus 14h 30m 7:00 AM Rome Tiburtina Bus Station 9:30 PM Lyon Perrache Bus Stop  Premium Economy $47
FlixBus 15h 20m 5:25 PM Rome Anagnina Bus Station 8:45 AM Lyon Lyon Avenue Tony Garnier Bus Stop  Economy $59
FlixBus 15h 30m 11:35 PM Rome Anagnina Bus Station 3:05 PM Lyon Lyon Avenue Tony Garnier Bus Stop  Economy $62
FlixBus 15h 40m 5:05 PM Rome Tiburtina Bus Station 8:45 AM Lyon Lyon Avenue Tony Garnier Bus Stop  Economy $66

Best Price Offer: The price for the cheapest bus from Rome to Lyon is $35 on 9/3/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Rome and Lyon

See here how frequent the connections between Rome and Lyon are, during different times and days of the week.
Saturday is the busiest day, with more than 33 daily buses from Rome to Lyon. Tuesday has instead the fewest connections, with only 19 daily coaches between Rome and Lyon.
The busiest time of the day is the Evening, with 62 buses from Rome to Lyon, while Night sees the fewest connections between Rome and Lyon, with 12 offers.

Facts about the bus from Rome to Lyon

Compare all providers like FlixBus, Itabus and BlaBlaCar Bus that travel 26 times every day by bus from Rome to Lyon in one click! Book your bus ticket from Rome to Lyon starting from $35!

Cheapest Bus $35
Fastest Bus 14h 30m
Earliest Bus 1:20 AM
Latest Bus 11:35 PM
Daily Bus Routes 26 Ø
Distance 465.5 miles
Bus Companies FlixBus, Itabus and BlaBlaCar Bus

Cheapest bus connections from Rome to Lyon

Every day, 26 buses from 3 bus companies leave Rome for Lyon: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 08/26/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 08/23
Monday 08/24
Tuesday 08/25
Wednesday 08/26
$124
Thursday 08/27
$58
Friday 08/28
$94
Saturday 08/29
$71
Sunday 08/30
$60
Monday 08/31
$93
Tuesday 09/01
$41
Wednesday 09/02
$53
Thursday 09/03
$35
Friday 09/04
$53
Saturday 09/05
$37
Sunday 09/06
$48
Monday 09/07
$36
Tuesday 09/08
$38
Wednesday 09/09
$53
Thursday 09/10
$36
Friday 09/11
$47
Saturday 09/12
$47
Sunday 09/13
$47
Monday 09/14
$37
Tuesday 09/15
$36
Wednesday 09/16
$59
Thursday 09/17
$38
Friday 09/18
$47
Saturday 09/19

The cheapest time to travel from Rome to Lyon

See here on which day and which time of the day you can find the cheapest bus ticket from Rome to Lyon, for the next 30 days.
With a price starting from $34, Saturday is the cheapest day for a bus from Rome to Lyon. Sunday instead is the most expensive day with prices starting from $47.
Night is the cheapest day time for bus tickets from Rome to Lyon, with $34. Evening is the most expensive time of the day with prices starting from $62.

How to save money travelling from Rome to Lyon

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Lyon in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Lyon, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Rome to Lyon are also emptier.

Beloved bus companies from Rome to Lyon

These are the most booked bus companies between Rome to Lyon from our users.

Itabus from Rome to Lyon

Itabus

Here you will find the key facts about the Itabus bus route Rome to Lyon:

Cheapest Price $41
Fastest Bus 14h 30m
Earliest Bus 7:00 AM
Last Bus 9:45 PM
Daily Connections 12 Ø
Found on 8/26/2026

All bus stations and stops in Rome and Lyon

In the map below, you can see where to find all bus stations in Rome and Lyon.

Service and Comfort on the bus from Rome to Lyon

Want to know which seat classes are available on the buses from Rome to Lyon? Or which bus companies serve the route Rome to Lyon? Below you will find answers to your questions.

FAQs about the Rome to Lyon bus

How much does a Rome Lyon bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $35 and takes 16h 25m to reach Lyon. Compare offers to save money!

How much could I save by comparing buses from Rome to Lyon?

This route is offered by 3 companies with a range of ticket prices between $35 and $274. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Lyon.

On average, how many connections are available from Rome to Lyon each day?

Every day, the Rome to Lyon bus route is served by approximately 26 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Rome to Lyon take?

The fastest bus from Rome to Lyon is offered by Itabus and takes 14h 30m. Bus tickets for this connection cost $53. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Rome to Lyon?

The earliest bus arriving in Lyon from Rome starts at 1:20 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Rome to Lyon?

The latest bus trip departing from Rome for Lyon starts at 11:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Rome Lyon route?

When traveling by bus from Rome to Lyon, passengers can travel with FlixBus, Itabus and BlaBlaCar Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Rome and Lyon?

You can check all the direct connections between Rome and Lyon by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Itabus and BlaBlaCar Bus.

What can I take with me on the Rome to Lyon bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Rome Lyon bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Lyon bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Lyon on your planned travel date.

How does CheckMyBus find the best bus deals from Rome to Lyon?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 26 daily trips between Rome and Lyon. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Rome to Lyon?

Prices and availability for 26 trips between Rome and Lyon change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Rome to Lyon

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Rome and to Lyon

Here’s an overview of the most popular bus routes to Rome and to Lyon. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses Riccione to Rome Buses Riccione to Rome
From Mestre to Rome bus From Mestre to Rome bus
Bus from Montpellier to Rome Bus from Montpellier to Rome
Bus from Genoa to Rome Bus from Genoa to Rome
Bus to Lyon from Massy Bus to Lyon from Massy
Buses Bern - Lyon Buses Bern - Lyon
Buses from Bilbao to Lyon Buses from Bilbao to Lyon
Bus Basel - Lyon Bus Basel - Lyon
Popular Airport Shuttles to Rome and to Lyon
CheckMyBus › Buses in Italy › Bus to Rome › Bus to Lyon

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.