Bus Mezcales to San Luis Potosí - Compare all Companies

Compare all timetables for the bus from Mezcales to San Luis Potosí

Here is a selection of the cheapest bus trips from the schedule from Mezcales to San Luis Potosí from various bus operators like ETN Autobuses for the next days.

today

tomorrow

Monday

Tuesday

Wednesday

$158

Thursday

Friday

Cheapest bus trips Wednesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	ETN Autobuses	12h 20m	2:50 PM	Mezcales	Vallarte Plus	3:10 AM	San Luis Potosí	Central Bus Station		Premium Economy	$158	A Bus from ETN Autobuses goes from Vallarte Plus, Mezcales (Mexico) at 10/28/2026 2:50:00 PM to Central Bus Station, San Luis Potosí (Mexico) arriving at 10/29/2026 3:10:00 AM. 50 Premium Economy ticket for $158 per person are available. Travel duration is 12h 20m

Did you know that if you travel from Mezcales to San Luis Potosí via Puerto Vallarta, you can save more than $56? You will find the corresponding connections below.
- Primera Plus
  
  Save more than 35%
  
  9h 25m
  
  Mezcales
  
  8 mi
  
  9:20 PM
  
  Puerto Vallarta
  Central Bus Station
  
  6:45 AM
  
  San Luis Potosí
  Central Bus Station
  
  0 mi
  
  Economy
  
  $102
  
  A Bus from Primera Plus goes from Central Bus Station, Puerto Vallarta (Mexico) at 10/28/2026 9:20:00 PM to Central Bus Station, San Luis Potosí (Mexico) arriving at 10/29/2026 6:45:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 9h 25m
Did you know that if you travel from Mezcales to San Luis Potosí via Aguascalientes, you can save more than $63? You can find the corresponding connections below.
- Futura
  
  15h 21m
  
  0
  
  5:49 PM
  
  Mezcales
  Primera Plus
  
  3:00 AM
  
  Aguascalientes
  Central Bus Station
  
  0
  
  Economy
  
  $87
  
  A Bus from Futura goes from Primera Plus, Mezcales (Mexico) at 10/25/2026 5:49:00 PM to Central Bus Station, Aguascalientes (Mexico) arriving at 10/26/2026 3:00:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 9h 11m
- Flix Mexico
  
  2h 45m
  
  0
  
  6:25 AM
  
  Aguascalientes
  Ignacio Valtierra Bus Stop
  
  9:10 AM
  
  San Luis Potosí
  Soriana El Paseo Bus Station
  
  0
  
  Economy
  
  $8
  
  A Bus from Flix Mexico goes from Ignacio Valtierra Bus Stop, Aguascalientes (Mexico) at 10/26/2026 6:25:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 10/26/2026 9:10:00 AM. 50 Economy ticket for $8 per person are available. Travel duration is 2h 45m
Travel time is 3h 1m longer, but you will save $63

Best Price Offer: The price for the cheapest bus from Mezcales to San Luis Potosí is $153 on 11/11/2026. Flexible travelers save on ticket prices.

Facts about the bus from Mezcales to San Luis Potosí

Compare all providers like ETN Autobuses that travel 1 times every day by bus from Mezcales to San Luis Potosí in one click! Book your bus ticket from Mezcales to San Luis Potosí starting from $153!

Cheapest Bus	$153
Fastest Bus	12h 20m
Earliest Bus	2:50 PM
Latest Bus	2:50 PM
Daily Bus Routes	1 Ø
Distance	295.3 miles
Bus Companies	ETN Autobuses

Cheapest bus connections from Mezcales to San Luis Potosí

Every day, 1 buses from 1 bus companies leave Mezcales for San Luis Potosí: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/24/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 10/18

Monday 10/19

Tuesday 10/20

Wednesday 10/21

Thursday 10/22

Friday 10/23

Saturday 10/24

Sunday 10/25

Monday 10/26

Tuesday 10/27

Wednesday 10/28

$158

Thursday 10/29

Friday 10/30

Saturday 10/31

Sunday 11/01

Monday 11/02

Tuesday 11/03

$156

Wednesday 11/04

$156

Thursday 11/05

Friday 11/06

Saturday 11/07

Sunday 11/08

Monday 11/09

Tuesday 11/10

$154

Wednesday 11/11

$153

Thursday 11/12

Friday 11/13

Saturday 11/14

How to save money travelling from Mezcales to San Luis Potosí

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mezcales to San Luis Potosí in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mezcales to San Luis Potosí, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mezcales to San Luis Potosí are also emptier.

All bus stations and stops in Mezcales and San Luis Potosí

In the map below, you can see where to find all bus stations in Mezcales and San Luis Potosí.

Primera Plus

Blvrd Riviera Nayarit 171

Central Bus Station

Av Benito Juarez 250

Soriana El Paseo Bus Station

Doctor Salvador Nava Martínez 405

Av Constitución / Manual José Othón Bus Stop

Avenida Constitución 300

Barrio de Santiago

Trojes del Horizonte

Service and Comfort on the bus from Mezcales to San Luis Potosí

Want to know which seat classes are available on the buses from Mezcales to San Luis Potosí? Or which bus companies serve the route Mezcales to San Luis Potosí? Below you will find answers to your questions.

FAQs about the Mezcales to San Luis Potosí bus

How much does a Mezcales San Luis Potosí bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $153 and takes 12h 20m to reach San Luis Potosí. Compare offers to save money!

How much could I save by comparing buses from Mezcales to San Luis Potosí?

This route is offered by 1 companies with a range of ticket prices between $153 and $158. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Luis Potosí.

On average, how many connections are available from Mezcales to San Luis Potosí each day?

Every day, the Mezcales to San Luis Potosí bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mezcales to San Luis Potosí take?

The fastest bus from Mezcales to San Luis Potosí is offered by ETN Autobuses and takes 12h 20m. Bus tickets for this connection cost $158. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mezcales to San Luis Potosí?

The earliest bus arriving in San Luis Potosí from Mezcales starts at 2:50 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mezcales to San Luis Potosí?

The latest bus trip departing from Mezcales for San Luis Potosí starts at 2:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mezcales San Luis Potosí route?

When traveling by bus from Mezcales to San Luis Potosí, passengers can travel with ETN Autobuses. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mezcales and San Luis Potosí?

You can check all the direct connections between Mezcales and San Luis Potosí by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: ETN Autobuses.

What can I take with me on the Mezcales to San Luis Potosí bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mezcales San Luis Potosí bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mezcales San Luis Potosí bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mezcales to San Luis Potosí on your planned travel date.

How does CheckMyBus find the best bus deals from Mezcales to San Luis Potosí?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 1 daily trips between Mezcales and San Luis Potosí. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Mezcales to San Luis Potosí?

Prices and availability for 1 trips between Mezcales and San Luis Potosí change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Mezcales to San Luis Potosí

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Mezcales and to San Luis Potosí

Here’s an overview of the most popular bus routes to Mezcales and to San Luis Potosí. Simply click on the connection of your choice, and you will find all the details about your bus route!