Which bus from Messina to Milan is the cheapest?

Compare all bus companies and find the best price: Bus tickets from $56
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Messina to Milan

Here is a selection of the cheapest bus trips from the schedule from Messina to Milan from various bus operators like FlixBus, Itabus or Autoservizi Salemi for the next days.

today
$56
tomorrow
$67
Friday
$64
Saturday
$67
Sunday
$69
Monday
$67
Tuesday
$67

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 20h 45m 10:55 AM Messina Piazza della Repubblica 7:40 AM Milan San Donato Bus Station  Economy $56
Itabus 19h 5m 9:35 PM Messina Central Station 4:40 PM Milan Lampugnano Bus Station  Premium Economy $56
FlixBus 19h 10m 10:55 AM Messina Piazza della Repubblica 6:05 AM Milan Lampugnano Bus Station  Economy $67
Autoservizi Salemi 15h 55m 9:15 PM Messina Piazza della Repubblica 1:10 PM Milan San Donato Bus Station  Economy $84
Autoservizi Salemi 16h 35m 9:15 PM Messina Piazza della Repubblica 1:50 PM Milan Lampugnano Bus Station  Economy $84
  • Did you know that if you travel from Messina to Milan via Rome, you can save more than $43? You can find the corresponding connections below.
    • Interbus
      10h 50m
      0
      2:15 PM
      Messina
      Central Station
      3:25 PM
      Rome
      Appia/Quarto Miglio
      0
      Interbus
      Economy
      $3
      • Waiting Time 1h 10m
    • FlixBus
      8h 30m
      0
      4:35 PM
      Rome
      Tiburtina Bus Station
      1:05 AM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $10
    Travel Time is 5h 5m shorter, and you will save $43

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 19h 5m 9:35 PM Messina Central Station 4:40 PM Milan Lampugnano Bus Station  Premium Economy $67
FlixBus 19h 25m 1:30 AM Messina Piazza della Repubblica 8:55 PM Milan San Donato Bus Station  Economy $77
FlixBus 20h 10m 1:30 AM Messina Piazza della Repubblica 9:40 PM Milan Lampugnano Bus Station  Economy $82
FlixBus 17h 30m 8:15 PM Messina Piazza della Repubblica 1:45 PM Milan Lampugnano Bus Station  Economy $86
  • Did you know that if you travel from Messina to Milan via Rome, you can save more than $54? You can find the corresponding connections below.
    • Interbus
      10h 50m
      0
      2:15 PM
      Messina
      Central Station
      3:25 PM
      Rome
      Appia/Quarto Miglio
      0
      Interbus
      Economy
      $3
      • Waiting Time 1h 10m
    • FlixBus
      8h 30m
      0
      4:35 PM
      Rome
      Tiburtina Bus Station
      1:05 AM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $10
    Travel Time is 6h 40m shorter, and you will save $54

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 21h 10m 1:30 AM Messina Piazza della Repubblica 10:40 PM Milan Lampugnano Bus Station  Economy $64
Itabus 19h 5m 9:35 PM Messina Piazza della Repubblica 4:40 PM Milan Lampugnano Bus Station  Economy $65
FlixBus 19h 25m 1:30 AM Messina Piazza della Repubblica 8:55 PM Milan San Donato Bus Station  Economy $74
FlixBus 17h 30m 8:15 PM Messina Piazza della Repubblica 1:45 PM Milan Lampugnano Bus Station  Economy $79
  • Did you know that if you travel from Messina to Milan via Rome, you can save more than $51? You can find the corresponding connections below.
    • Interbus
      9h 44m
      0
      2:15 PM
      Messina
      Central Station
      3:25 PM
      Rome
      Appia/Quarto Miglio
      0
      Interbus
      Economy
      $3
      • Waiting Time 0h 20m
    • FlixBus
      8h 14m
      0
      3:45 PM
      Rome
      Tiburtina Bus Station
      11:59 PM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $10
    Travel Time is 7h 46m shorter, and you will save $51

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 19h 5m 9:35 PM Messina Central Station 3:40 PM Milan Lampugnano Bus Station  Premium Economy $67
FlixBus 17h 30m 8:15 PM Messina Piazza della Repubblica 12:45 PM Milan San Donato Bus Station  Economy $79
FlixBus 20h 10m 1:30 AM Messina Piazza della Repubblica 9:40 PM Milan Lampugnano Bus Station  Economy $79
Autoservizi Salemi 16h 35m 9:15 PM Messina Piazza della Repubblica 12:50 PM Milan Lampugnano Bus Station  Economy $89
Autoservizi Salemi 15h 55m 9:15 PM Messina Piazza della Repubblica 12:10 PM Milan San Donato Bus Station  Economy $89
  • Did you know that if you travel from Messina to Milan via Rome, you can save more than $54? You can find the corresponding connections below.
    • Interbus
      9h 44m
      0
      2:15 PM
      Messina
      Central Station
      3:25 PM
      Rome
      Appia/Quarto Miglio
      0
      Interbus
      Economy
      $3
      • Waiting Time 0h 20m
    • FlixBus
      8h 14m
      0
      3:45 PM
      Rome
      Tiburtina Bus Station
      11:59 PM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $10
    Travel Time is 5h 11m shorter, and you will save $54

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 18h 20m 8:15 PM Messina Piazza della Repubblica 2:35 PM Milan San Donato Bus Station  Economy $69
FlixBus 17h 30m 8:15 PM Messina Piazza della Repubblica 1:45 PM Milan Lampugnano Bus Station  Economy $70
Itabus 19h 5m 9:35 PM Messina Central Station 4:40 PM Milan Lampugnano Bus Station  Premium Economy $79
FlixBus 20h 25m 9:30 PM Messina Piazza della Repubblica 5:55 PM Milan Lampugnano Bus Station  Economy $96
  • Did you know that if you travel from Messina to Milan via Rome, you can save more than $56? You can find the corresponding connections below.
    • Interbus
      9h 44m
      0
      2:15 PM
      Messina
      Central Station
      3:25 PM
      Rome
      Appia/Quarto Miglio
      0
      Interbus
      Economy
      $3
      • Waiting Time 0h 20m
    • FlixBus
      8h 14m
      0
      3:45 PM
      Rome
      Tiburtina Bus Station
      11:59 PM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $10
    Travel Time is 7h 46m shorter, and you will save $56

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 19h 5m 9:35 PM Messina Central Station 4:40 PM Milan Lampugnano Bus Station  Premium Economy $67
FlixBus 17h 30m 8:15 PM Messina Piazza della Repubblica 1:45 PM Milan Lampugnano Bus Station  Economy $81
FlixBus 18h 20m 8:15 PM Messina Piazza della Repubblica 2:35 PM Milan San Donato Bus Station  Economy $89
Autoservizi Salemi 15h 55m 9:15 PM Messina Piazza della Repubblica 1:10 PM Milan San Donato Bus Station  Economy $90
Autoservizi Salemi 16h 35m 9:15 PM Messina Piazza della Repubblica 1:50 PM Milan Lampugnano Bus Station  Economy $90
  • Did you know that if you travel from Messina to Milan via Rome, you can save more than $54? You can find the corresponding connections below.
    • Interbus
      9h 44m
      0
      2:15 PM
      Messina
      Central Station
      3:25 PM
      Rome
      Appia/Quarto Miglio
      0
      Interbus
      Economy
      $3
      • Waiting Time 0h 20m
    • FlixBus
      8h 14m
      0
      3:45 PM
      Rome
      Tiburtina Bus Station
      11:59 PM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $10
    Travel Time is 6h 11m shorter, and you will save $54

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 19h 5m 9:35 PM Messina Central Station 4:40 PM Milan Lampugnano Bus Station  Premium Economy $67
FlixBus 20h 10m 1:30 AM Messina Piazza della Repubblica 9:40 PM Milan Lampugnano Bus Station  Economy $84
FlixBus 20h 50m 1:30 AM Messina Piazza della Repubblica 10:20 PM Milan San Donato Bus Station  Economy $86
FlixBus 17h 30m 8:15 PM Messina Piazza della Repubblica 1:45 PM Milan Lampugnano Bus Station  Economy $86
  • Did you know that if you travel from Messina to Milan via Rome, you can save more than $54? You can find the corresponding connections below.
    • Interbus
      9h 44m
      0
      2:15 PM
      Messina
      Central Station
      3:25 PM
      Rome
      Appia/Quarto Miglio
      0
      Interbus
      Economy
      $3
      • Waiting Time 0h 20m
    • FlixBus
      8h 14m
      0
      3:45 PM
      Rome
      Tiburtina Bus Station
      11:59 PM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $10
    Travel Time is 7h 46m shorter, and you will save $54

Best Price Offer: The price for the cheapest bus from Messina to Milan is $56 on 10/21/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Messina and Milan

See here how frequent the connections between Messina and Milan are, during different times and days of the week.
Wednesday is the busiest day, with more than 24 daily buses from Messina to Milan. Thursday has instead the fewest connections, with only 9 daily coaches between Messina and Milan.
The busiest time of the day is the Evening, with 68 buses from Messina to Milan, while Night sees the fewest connections between Messina and Milan, with 14 offers.

Facts about the bus from Messina to Milan

Compare all providers like FlixBus, Itabus and Autoservizi Salemi that travel 14 times every day by bus from Messina to Milan in one click! Book your bus ticket from Messina to Milan starting from $56!

Cheapest Bus $56
Fastest Bus 14h 55m
Earliest Bus 1:30 AM
Latest Bus 9:35 PM
Daily Bus Routes 14 Ø
Distance 599.7 miles
Bus Companies FlixBus, Itabus and Autoservizi Salemi

Cheapest bus connections from Messina to Milan

Every day, 14 buses from 3 bus companies leave Messina for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/21/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 10/18
Monday 10/19
Tuesday 10/20
Wednesday 10/21
$56
Thursday 10/22
$77
Friday 10/23
$64
Saturday 10/24
$79
Sunday 10/25
$69
Monday 10/26
$81
Tuesday 10/27
$84
Wednesday 10/28
$72
Thursday 10/29
$94
Friday 10/30
$97
Saturday 10/31
$76
Sunday 11/01
$83
Monday 11/02
$76
Tuesday 11/03
$76
Wednesday 11/04
$73
Thursday 11/05
$65
Friday 11/06
$90
Saturday 11/07
$72
Sunday 11/08
$67
Monday 11/09
$58
Tuesday 11/10
$56
Wednesday 11/11
$60
Thursday 11/12
$62
Friday 11/13
$60
Saturday 11/14

The cheapest time to travel from Messina to Milan

See here on which day and which time of the day you can find the cheapest bus ticket from Messina to Milan, for the next 30 days.
With a price starting from $56, Wednesday is the cheapest day for a bus from Messina to Milan. Sunday instead is the most expensive day with prices starting from $67.
Morning is the cheapest day time for bus tickets from Messina to Milan, with $56. Evening is the most expensive time of the day with prices starting from $56.

How to save money travelling from Messina to Milan

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Messina to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Messina to Milan, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Messina to Milan are also emptier.

All bus stations and stops in Messina and Milan

In the map below, you can see where to find all bus stations in Messina and Milan.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Messina to Milan? Compare all modes of transports from Messina to Milan.

Service and Comfort on the bus from Messina to Milan

Want to know which seat classes are available on the buses from Messina to Milan? Or which bus companies serve the route Messina to Milan? Below you will find answers to your questions.

FAQs about the Messina to Milan bus

How much does a Messina Milan bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $56 and takes 20h 45m to reach Milan. Compare offers to save money!

How much could I save by comparing buses from Messina to Milan?

This route is offered by 3 companies with a range of ticket prices between $56 and $148. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Milan.

On average, how many connections are available from Messina to Milan each day?

Every day, the Messina to Milan bus route is served by approximately 14 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Messina to Milan take?

The fastest bus from Messina to Milan is offered by Autoservizi Salemi and takes 14h 55m. Bus tickets for this connection cost $89. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Messina to Milan?

The earliest bus arriving in Milan from Messina starts at 1:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Messina to Milan?

The latest bus trip departing from Messina for Milan starts at 9:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Messina Milan route?

When traveling by bus from Messina to Milan, passengers can travel with FlixBus, Itabus and Autoservizi Salemi. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Messina and Milan?

You can check all the direct connections between Messina and Milan by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Itabus and Autoservizi Salemi.

What can I take with me on the Messina to Milan bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Messina Milan bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Messina Milan bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Messina to Milan on your planned travel date.

How does CheckMyBus find the best bus deals from Messina to Milan?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 14 daily trips between Messina and Milan. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Messina to Milan?

Prices and availability for 14 trips between Messina and Milan change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Messina to Milan

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Messina and to Milan

Here’s an overview of the most popular bus routes to Messina and to Milan. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses from Vibo Valentia to Messina Buses from Vibo Valentia to Messina
Bus Ciampino - Messina Bus Ciampino - Messina
Salerno to Messina bus Salerno to Messina bus
Buses from Verona to Messina Buses from Verona to Messina
Buses Alessandria - Milan Buses Alessandria - Milan
Bus to Milan from Mulhouse Bus to Milan from Mulhouse
Bus from Lido degli Estensi to Milan Bus from Lido degli Estensi to Milan
Bus Catania to Milan Bus Catania to Milan
Popular Airport Shuttles to Messina and to Milan
CheckMyBus › Buses in Italy › Bus to Messina › Bus to Milan

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.