Bus Mersin to Istanbul: Compare prices and save money

Compare all timetables for the bus from Mersin to Istanbul

Here is a selection of the cheapest bus trips from the schedule from Mersin to Istanbul from various bus operators like FlixBus, Metro Turizm or Kamil Koc for the next days.

today

tomorrow

$34

Saturday

$32

Sunday

$33

Monday

$33

Tuesday

$34

Wednesday

$32

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	13h 25m	12:00 PM	Mersin	Yeni Otogar	1:25 AM	Istanbul	Alibeyköy Otogarı	Economy	$34	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 10/23/2026 12:00:00 PM to Alibeyköy Otogarı, Istanbul (Turkey) arriving at 10/24/2026 1:25:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 13h 25m
FlixBus	13h 25m	11:00 PM	Mersin	Yeni Otogar	12:25 PM	Istanbul	Alibeyköy Otogarı	Economy	$34	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 10/23/2026 11:00:00 PM to Alibeyköy Otogarı, Istanbul (Turkey) arriving at 10/24/2026 12:25:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 13h 25m
FlixBus	13h 45m	12:00 PM	Mersin	Yeni Otogar	1:45 AM	Istanbul	Otogar Bus Station	Economy	$34	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 10/23/2026 12:00:00 PM to Otogar Bus Station, Istanbul (Turkey) arriving at 10/24/2026 1:45:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 13h 45m
Metro Turizm	16h 0m	10:30 PM	Mersin	Yeni Otogar	2:30 PM	Istanbul	Alibeyköy Otogarı	Economy	$36	A Bus from Metro Turizm goes from Yeni Otogar, Mersin (Turkey) at 10/23/2026 10:30:00 PM to Alibeyköy Otogarı, Istanbul (Turkey) arriving at 10/24/2026 2:30:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 16h 0m
Metro Turizm	14h 0m	11:00 PM	Mersin	Yeni Otogar	1:00 PM	Istanbul	Alibeyköy Otogarı	Economy	$36	A Bus from Metro Turizm goes from Yeni Otogar, Mersin (Turkey) at 10/23/2026 11:00:00 PM to Alibeyköy Otogarı, Istanbul (Turkey) arriving at 10/24/2026 1:00:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 14h 0m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Kamil Koc	13h 45m	12:00 PM	Mersin	Central Station	1:45 AM	Istanbul	Esenler Bus Station	Economy	$32	A Bus from Kamil Koc goes from Central Station, Mersin (Turkey) at 10/24/2026 12:00:00 PM to Esenler Bus Station, Istanbul (Turkey) arriving at 10/25/2026 1:45:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 13h 45m
Kamil Koc	15h 45m	5:30 PM	Mersin	Central Station	9:15 AM	Istanbul	Esenler Bus Station	Economy	$32	A Bus from Kamil Koc goes from Central Station, Mersin (Turkey) at 10/24/2026 5:30:00 PM to Esenler Bus Station, Istanbul (Turkey) arriving at 10/25/2026 9:15:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 15h 45m
FlixBus	12h 0m	12:00 PM	Mersin	Yeni Otogar	12:00 AM	Istanbul	Dudullu Bus Station	Economy	$33	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 10/24/2026 12:00:00 PM to Dudullu Bus Station, Istanbul (Turkey) arriving at 10/25/2026 12:00:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 12h 0m
FlixBus	13h 35m	5:30 PM	Mersin	Yeni Otogar	7:05 AM	Istanbul	Dudullu Bus Station	Economy	$33	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 10/24/2026 5:30:00 PM to Dudullu Bus Station, Istanbul (Turkey) arriving at 10/25/2026 7:05:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 13h 35m
Metro Turizm	16h 30m	10:30 PM	Mersin	Yeni Otogar	3:00 PM	Istanbul	Otogar Bus Station	Economy	$36	A Bus from Metro Turizm goes from Yeni Otogar, Mersin (Turkey) at 10/24/2026 10:30:00 PM to Otogar Bus Station, Istanbul (Turkey) arriving at 10/25/2026 3:00:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 16h 30m

Cheapest bus trips Sunday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	12h 0m	12:00 PM	Mersin	Yeni Otogar	12:00 AM	Istanbul	Dudullu Bus Station		Economy	$33	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 10/25/2026 12:00:00 PM to Dudullu Bus Station, Istanbul (Turkey) arriving at 10/26/2026 12:00:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 12h 0m
	FlixBus	12h 15m	11:00 PM	Mersin	Yeni Otogar	11:15 AM	Istanbul	Dudullu Bus Station		Economy	$33	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 10/25/2026 11:00:00 PM to Dudullu Bus Station, Istanbul (Turkey) arriving at 10/26/2026 11:15:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 12h 15m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	12h 0m	12:00 PM	Mersin	Yeni Otogar	12:00 AM	Istanbul	Dudullu Bus Station	Economy	$33	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 10/26/2026 12:00:00 PM to Dudullu Bus Station, Istanbul (Turkey) arriving at 10/27/2026 12:00:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 12h 0m
FlixBus	13h 35m	5:30 PM	Mersin	Yeni Otogar	7:05 AM	Istanbul	Dudullu Bus Station	Economy	$33	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 10/26/2026 5:30:00 PM to Dudullu Bus Station, Istanbul (Turkey) arriving at 10/27/2026 7:05:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 13h 35m
FlixBus	12h 15m	11:00 PM	Mersin	Yeni Otogar	11:15 AM	Istanbul	Dudullu Bus Station	Economy	$33	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 10/26/2026 11:00:00 PM to Dudullu Bus Station, Istanbul (Turkey) arriving at 10/27/2026 11:15:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 12h 15m
Metro Turizm	16h 0m	10:30 PM	Mersin	Yeni Otogar	2:30 PM	Istanbul	Alibeyköy Otogarı	Economy	$36	A Bus from Metro Turizm goes from Yeni Otogar, Mersin (Turkey) at 10/26/2026 10:30:00 PM to Alibeyköy Otogarı, Istanbul (Turkey) arriving at 10/27/2026 2:30:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 16h 0m
Metro Turizm	14h 0m	11:00 PM	Mersin	Yeni Otogar	1:00 PM	Istanbul	Alibeyköy Otogarı	Economy	$36	A Bus from Metro Turizm goes from Yeni Otogar, Mersin (Turkey) at 10/26/2026 11:00:00 PM to Alibeyköy Otogarı, Istanbul (Turkey) arriving at 10/27/2026 1:00:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 14h 0m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	13h 25m	12:00 PM	Mersin	Yeni Otogar	1:25 AM	Istanbul	Alibeyköy Otogarı	Economy	$34	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 10/27/2026 12:00:00 PM to Alibeyköy Otogarı, Istanbul (Turkey) arriving at 10/28/2026 1:25:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 13h 25m
FlixBus	13h 25m	11:00 PM	Mersin	Yeni Otogar	12:25 PM	Istanbul	Alibeyköy Otogarı	Economy	$34	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 10/27/2026 11:00:00 PM to Alibeyköy Otogarı, Istanbul (Turkey) arriving at 10/28/2026 12:25:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 13h 25m
FlixBus	13h 45m	12:00 PM	Mersin	Yeni Otogar	1:45 AM	Istanbul	Otogar Bus Station	Economy	$34	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 10/27/2026 12:00:00 PM to Otogar Bus Station, Istanbul (Turkey) arriving at 10/28/2026 1:45:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 13h 45m
Metro Turizm	16h 0m	10:30 PM	Mersin	Yeni Otogar	2:30 PM	Istanbul	Alibeyköy Otogarı	Economy	$36	A Bus from Metro Turizm goes from Yeni Otogar, Mersin (Turkey) at 10/27/2026 10:30:00 PM to Alibeyköy Otogarı, Istanbul (Turkey) arriving at 10/28/2026 2:30:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 16h 0m
Metro Turizm	14h 0m	11:00 PM	Mersin	Yeni Otogar	1:00 PM	Istanbul	Alibeyköy Otogarı	Economy	$36	A Bus from Metro Turizm goes from Yeni Otogar, Mersin (Turkey) at 10/27/2026 11:00:00 PM to Alibeyköy Otogarı, Istanbul (Turkey) arriving at 10/28/2026 1:00:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 14h 0m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Kamil Koc	13h 45m	12:00 PM	Mersin	Central Station	1:45 AM	Istanbul	Esenler Bus Station	Economy	$32	A Bus from Kamil Koc goes from Central Station, Mersin (Turkey) at 10/28/2026 12:00:00 PM to Esenler Bus Station, Istanbul (Turkey) arriving at 10/29/2026 1:45:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 13h 45m
Kamil Koc	15h 45m	5:30 PM	Mersin	Central Station	9:15 AM	Istanbul	Esenler Bus Station	Economy	$32	A Bus from Kamil Koc goes from Central Station, Mersin (Turkey) at 10/28/2026 5:30:00 PM to Esenler Bus Station, Istanbul (Turkey) arriving at 10/29/2026 9:15:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 15h 45m
FlixBus	13h 25m	12:00 PM	Mersin	Yeni Otogar	1:25 AM	Istanbul	Alibeyköy Otogarı	Economy	$33	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 10/28/2026 12:00:00 PM to Alibeyköy Otogarı, Istanbul (Turkey) arriving at 10/29/2026 1:25:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 13h 25m
FlixBus	15h 10m	5:30 PM	Mersin	Yeni Otogar	8:40 AM	Istanbul	Alibeyköy Otogarı	Economy	$33	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 10/28/2026 5:30:00 PM to Alibeyköy Otogarı, Istanbul (Turkey) arriving at 10/29/2026 8:40:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 15h 10m
Metro Turizm	16h 30m	10:30 PM	Mersin	Yeni Otogar	3:00 PM	Istanbul	Otogar Bus Station	Economy	$36	A Bus from Metro Turizm goes from Yeni Otogar, Mersin (Turkey) at 10/28/2026 10:30:00 PM to Otogar Bus Station, Istanbul (Turkey) arriving at 10/29/2026 3:00:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 16h 30m

Best Price Offer: The price for the cheapest bus from Mersin to Istanbul is $25 on 10/23/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Mersin and Istanbul

See here how frequent the connections between Mersin and Istanbul are, during different times and days of the week.

Saturday is the busiest day, with more than 16 daily buses from Mersin to Istanbul. Sunday has instead the fewest connections, with only 2 daily coaches between Mersin and Istanbul.

The busiest time of the day is the Evening, with 35 buses from Mersin to Istanbul, while Afternoon sees the fewest connections between Mersin and Istanbul, with 25 offers.

Facts about the bus from Mersin to Istanbul

Compare all providers like FlixBus, Metro Turizm and Kamil Koc that travel 10 times every day by bus from Mersin to Istanbul in one click! Book your bus ticket from Mersin to Istanbul starting from $25!

Cheapest Bus	$25
Fastest Bus	12h 0m
Earliest Bus	12:00 PM
Latest Bus	11:00 PM
Daily Bus Routes	10 Ø
Distance	420.4 miles
Bus Companies	FlixBus, Metro Turizm and Kamil Koc

Cheapest bus connections from Mersin to Istanbul

Every day, 10 buses from 3 bus companies leave Mersin for Istanbul: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/22/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 10/18

Monday 10/19

Tuesday 10/20

Wednesday 10/21

Thursday 10/22

$30

Friday 10/23

$25

Saturday 10/24

$25

Sunday 10/25

$25

Monday 10/26

$33

Tuesday 10/27

$34

Wednesday 10/28

$25

Thursday 10/29

$35

Friday 10/30

$25

Saturday 10/31

$25

Sunday 11/01

$36

Monday 11/02

$33

Tuesday 11/03

$25

Wednesday 11/04

$30

Thursday 11/05

$36

Friday 11/06

$25

Saturday 11/07

$38

Sunday 11/08

$35

Monday 11/09

$35

Tuesday 11/10

$35

Wednesday 11/11

$25

Thursday 11/12

$38

Friday 11/13

Saturday 11/14

The cheapest time to travel from Mersin to Istanbul

See here on which day and which time of the day you can find the cheapest bus ticket from Mersin to Istanbul, for the next 30 days.

With a price starting from $25, Sunday is the cheapest day for a bus from Mersin to Istanbul. Monday instead is the most expensive day with prices starting from $33.

Afternoon is the cheapest day time for bus tickets from Mersin to Istanbul, with $32. Afternoon is the most expensive time of the day with prices starting from $32.

How to save money travelling from Mersin to Istanbul

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mersin to Istanbul in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mersin to Istanbul, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mersin to Istanbul are also emptier.

Beloved bus companies from Mersin to Istanbul

These are the most booked bus companies between Mersin to Istanbul from our users.

Kamil Koc from Mersin to Istanbul

Here you will find the key facts about the Kamil Koc bus route Mersin to Istanbul:

Cheapest Price	$32
Fastest Bus	13h 45m
Earliest Bus	12:00 PM
Last Bus	11:00 PM
Daily Connections	3 Ø
Found on	9/28/2026

Latest reviews for bus companies on the route Mersin - Istanbul

Dersu, 9/1/2026

Berbat bir yolculuk oldu. 12 saatlik yolu 15 saatte aldık. Neredeyse köylere dahi girecekti. Çok kirli ve kaloriferi bozuk olduğundan yaz günü sıcak hava ile terleyerek yolculuk yaptık. Söylediğimiz d ... Berbat bir yolculuk oldu. 12 saatlik yolu 15 saatte aldık. Neredeyse köylere dahi girecekti. Çok kirli ve kaloriferi bozuk olduğundan yaz günü sıcak hava ile terleyerek yolculuk yaptık. Söylediğimiz de akşam bu sıcaklığı arayacaksınız gibi lakayt bir ifade söylendi.

All bus stations and stops in Mersin and Istanbul

In the map below, you can see where to find all bus stations in Mersin and Istanbul.

Yeni Otogar

Port

Bus Stop

Mut

Central Station

Gazi Mustafa Kemal Bulvarı 277

Alibeyköy Otogarı

Güzeltepe, Fatih Sultan Mehmet Blv 18

Dudullu Bus Station

Kible Sokak 38

Esenler Bus Station

Altıntepsi

Otogar Bus Station

Altıntepsi Mahallesi Bayrampasa-Istanbul

Samandira Bus Station

Tuna Cd 4

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Mersin to Istanbul? Compare all modes of transports from Mersin to Istanbul.

Service and Comfort on the bus from Mersin to Istanbul

Want to know which seat classes are available on the buses from Mersin to Istanbul? Or which bus companies serve the route Mersin to Istanbul? Below you will find answers to your questions.

FAQs about the Mersin to Istanbul bus

How much does a Mersin Istanbul bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $25 and takes 13h 45m to reach Istanbul. Compare offers to save money!

How much could I save by comparing buses from Mersin to Istanbul?

This route is offered by 3 companies with a range of ticket prices between $25 and $36. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Istanbul.

On average, how many connections are available from Mersin to Istanbul each day?

Every day, the Mersin to Istanbul bus route is served by approximately 10 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mersin to Istanbul take?

The fastest bus from Mersin to Istanbul is offered by FlixBus and takes 12h 0m. Bus tickets for this connection cost $33. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mersin to Istanbul?

The earliest bus arriving in Istanbul from Mersin starts at 12:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mersin to Istanbul?

The latest bus trip departing from Mersin for Istanbul starts at 11:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mersin Istanbul route?

When traveling by bus from Mersin to Istanbul, passengers can travel with FlixBus, Metro Turizm and Kamil Koc. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mersin and Istanbul?

You can check all the direct connections between Mersin and Istanbul by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Metro Turizm and Kamil Koc.

What can I take with me on the Mersin to Istanbul bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mersin Istanbul bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mersin Istanbul bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mersin to Istanbul on your planned travel date.

How does CheckMyBus find the best bus deals from Mersin to Istanbul?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 10 daily trips between Mersin and Istanbul. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Mersin to Istanbul?

Prices and availability for 10 trips between Mersin and Istanbul change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Mersin to Istanbul

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mersin and to Istanbul

Here’s an overview of the most popular bus routes to Mersin and to Istanbul. Simply click on the connection of your choice, and you will find all the details about your bus route!