Which bus from Madrid to Santander is the cheapest?

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Compare all timetables for the bus from Madrid to Santander

Here is a selection of the cheapest bus trips from the schedule from Madrid to Santander from various bus operators like ALSA or FlixBus for the next days.

today
$43
tomorrow
$47
Friday
$47
Saturday
$43
Sunday
$43
Monday
$49
Tuesday
$43

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ALSA 5h 45m 4:30 PM Madrid Avenida de América Bus Station 10:15 PM Santander Bus Station  Economy $43
ALSA 5h 30m 6:30 PM Madrid Avenida de América Bus Station 12:00 AM Santander Bus Station  Economy $43
ALSA 5h 45m 7:00 PM Madrid Avenida de América Bus Station 12:45 AM Santander Bus Station  Economy $43
FlixBus 19h 20m 11:30 PM Madrid Sur Bus Station 6:50 PM Santander Bus Station  Economy $110
FlixBus 16h 40m 4:40 PM Madrid Sur Bus Station 9:20 AM Santander Bus Station  Economy $153

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ALSA 5h 50m 8:00 AM Madrid Avenida de América Bus Station 1:50 PM Santander Bus Station  Economy $47
ALSA 5h 45m 10:30 AM Madrid Avenida de América Bus Station 4:15 PM Santander Bus Station  Economy $49
ALSA 5h 30m 1:00 PM Madrid Avenida de América Bus Station 6:30 PM Santander Bus Station  Economy $49
FlixBus 19h 20m 11:30 PM Madrid Sur Bus Station 6:50 PM Santander Bus Station  Economy $139
FlixBus 16h 40m 4:40 PM Madrid Sur Bus Station 9:20 AM Santander Bus Station  Economy $186

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ALSA 5h 30m 3:30 PM Madrid Avenida de América Bus Station 9:00 PM Santander Bus Station  Economy $47
ALSA 5h 45m 10:30 AM Madrid Avenida de América Bus Station 4:15 PM Santander Bus Station  Economy $49
ALSA 5h 45m 4:30 PM Madrid Avenida de América Bus Station 10:15 PM Santander Bus Station  Economy $49
FlixBus 16h 40m 4:40 PM Madrid Sur Bus Station 9:20 AM Santander Bus Station  Economy $121
FlixBus 19h 20m 11:30 PM Madrid Sur Bus Station 6:50 PM Santander Bus Station  Economy $129

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ALSA 5h 45m 10:30 AM Madrid Avenida de América Bus Station 4:15 PM Santander Bus Station  Economy $43
ALSA 5h 45m 4:30 PM Madrid Avenida de América Bus Station 10:15 PM Santander Bus Station  Economy $43
ALSA 5h 30m 6:30 PM Madrid Avenida de América Bus Station 12:00 AM Santander Bus Station  Economy $43
FlixBus 19h 20m 11:30 PM Madrid Sur Bus Station 6:50 PM Santander Bus Station  Economy $143
FlixBus 16h 40m 4:40 PM Madrid Sur Bus Station 9:20 AM Santander Bus Station  Economy $154

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ALSA 5h 30m 6:30 PM Madrid Avenida de América Bus Station 12:00 AM Santander Bus Station  Economy $43
ALSA 5h 45m 7:00 PM Madrid Avenida de América Bus Station 12:45 AM Santander Bus Station  Economy $43
ALSA 5h 45m 10:30 AM Madrid Avenida de América Bus Station 4:15 PM Santander Bus Station  Economy $49
FlixBus 16h 40m 4:40 PM Madrid Sur Bus Station 9:20 AM Santander Bus Station  Economy $132

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ALSA 5h 45m 10:30 AM Madrid Avenida de América Bus Station 4:15 PM Santander Bus Station  Economy $49
ALSA 5h 30m 1:00 PM Madrid Avenida de América Bus Station 6:30 PM Santander Bus Station  Economy $49
ALSA 5h 45m 4:30 PM Madrid Avenida de América Bus Station 10:15 PM Santander Bus Station  Economy $49
FlixBus 16h 40m 4:40 PM Madrid Sur Bus Station 9:20 AM Santander Bus Station  Economy $104
  • Did you know that if you travel from Madrid to Santander via Burgos, you can save more than $7? You can find the corresponding connections below.
    • ALSA
      5h 50m
      0
      8:00 AM
      Madrid
      Avenida de América Bus Station
      10:45 AM
      Burgos
      Bus Station
      0
      ALSA
      Economy
      $22
      • Waiting Time 0h 15m
    • ALSA
      2h 50m
      0
      11:00 AM
      Burgos
      Bus Station
      1:50 PM
      Santander
      Bus Station
      0
      ALSA
      Economy
      $20
    Travel time is 0h 20m longer, but you will save $7

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ALSA 5h 30m 1:00 PM Madrid Avenida de América Bus Station 6:30 PM Santander Bus Station  Economy $43
ALSA 5h 45m 4:30 PM Madrid Avenida de América Bus Station 10:15 PM Santander Bus Station  Economy $43
ALSA 5h 30m 6:30 PM Madrid Avenida de América Bus Station 12:00 AM Santander Bus Station  Economy $43
ALSA 5h 30m 3:00 PM Madrid Avenida de América Bus Station 8:30 PM Santander Bus Station  Economy $45
ALSA 5h 50m 8:00 AM Madrid Avenida de Aragon 1:50 PM Santander Bus Station  Economy $46

Best Price Offer: The price for the cheapest bus from Madrid to Santander is $3 on 8/24/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Madrid and Santander

See here how frequent the connections between Madrid and Santander are, during different times and days of the week.
Thursday is the busiest day, with more than 35 daily buses from Madrid to Santander. Monday has instead the fewest connections, with only 21 daily coaches between Madrid and Santander.
The busiest time of the day is the Afternoon, with 83 buses from Madrid to Santander, while Night sees the fewest connections between Madrid and Santander, with 26 offers.

Facts about the bus from Madrid to Santander

Compare all providers like ALSA and FlixBus that travel 27 times every day by bus from Madrid to Santander in one click! Book your bus ticket from Madrid to Santander starting from $3!

Cheapest Bus $3
Fastest Bus 5h 30m
Earliest Bus 12:30 AM
Latest Bus 6:30 PM
Daily Bus Routes 27 Ø
Distance 210.6 miles
Bus Companies ALSA and FlixBus

Cheapest bus connections from Madrid to Santander

Every day, 27 buses from 2 bus companies leave Madrid for Santander: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 08/26/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 08/23
Monday 08/24
Tuesday 08/25
Wednesday 08/26
$3
Thursday 08/27
$75
Friday 08/28
$3
Saturday 08/29
$143
Sunday 08/30
$3
Monday 08/31
$68
Tuesday 09/01
$3
Wednesday 09/02
$3
Thursday 09/03
$43
Friday 09/04
$3
Saturday 09/05
$3
Sunday 09/06
$3
Monday 09/07
$3
Tuesday 09/08
$3
Wednesday 09/09
$46
Thursday 09/10
$46
Friday 09/11
$47
Saturday 09/12
$3
Sunday 09/13
$50
Monday 09/14
$59
Tuesday 09/15
$46
Wednesday 09/16
$3
Thursday 09/17
$44
Friday 09/18
$47
Saturday 09/19

The cheapest time to travel from Madrid to Santander

See here on which day and which time of the day you can find the cheapest bus ticket from Madrid to Santander, for the next 30 days.
With a price starting from $3, Sunday is the cheapest day for a bus from Madrid to Santander. Thursday instead is the most expensive day with prices starting from $43.
Night is the cheapest day time for bus tickets from Madrid to Santander, with $3. Morning is the most expensive time of the day with prices starting from $43.

How to save money travelling from Madrid to Santander

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Madrid to Santander in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Madrid to Santander, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Madrid to Santander are also emptier.

Beloved bus companies from Madrid to Santander

These are the most booked bus companies between Madrid to Santander from our users.

ALSA from Madrid to Santander

ALSA

Here you will find the key facts about the ALSA bus route Madrid to Santander:

Cheapest Price $43
Fastest Bus 5h 30m
Earliest Bus 12:30 AM
Last Bus 6:30 PM
Daily Connections 25 Ø
Found on 8/25/2026

All bus stations and stops in Madrid and Santander

In the map below, you can see where to find all bus stations in Madrid and Santander.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Madrid to Santander? Compare all modes of transports from Madrid to Santander.

Service and Comfort on the bus from Madrid to Santander

Want to know which seat classes are available on the buses from Madrid to Santander? Or which bus companies serve the route Madrid to Santander? Below you will find answers to your questions.

FAQs about the Madrid to Santander bus

How much does a Madrid Santander bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $3 and takes 5h 45m to reach Santander. Compare offers to save money!

How much could I save by comparing buses from Madrid to Santander?

This route is offered by 2 companies with a range of ticket prices between $3 and $186. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santander.

On average, how many connections are available from Madrid to Santander each day?

Every day, the Madrid to Santander bus route is served by approximately 27 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Madrid to Santander take?

The fastest bus from Madrid to Santander is offered by ALSA and takes 5h 30m. Bus tickets for this connection cost $71. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Madrid to Santander?

The earliest bus arriving in Santander from Madrid starts at 12:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Madrid to Santander?

The latest bus trip departing from Madrid for Santander starts at 6:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Madrid Santander route?

When traveling by bus from Madrid to Santander, passengers can travel with ALSA and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Madrid and Santander?

You can check all the direct connections between Madrid and Santander by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: ALSA and FlixBus.

What can I take with me on the Madrid to Santander bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Madrid Santander bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Madrid Santander bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Madrid to Santander on your planned travel date.

How does CheckMyBus find the best bus deals from Madrid to Santander?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 27 daily trips between Madrid and Santander. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Madrid to Santander?

Prices and availability for 27 trips between Madrid and Santander change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Madrid to Santander

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Madrid and to Santander

Here’s an overview of the most popular bus routes to Madrid and to Santander. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses from Ortigosa del Monte to Madrid Buses from Ortigosa del Monte to Madrid
Buses Vera to Madrid Buses Vera to Madrid
Bus to Madrid from Navalmoral de la Mata Bus to Madrid from Navalmoral de la Mata
From Cáceres‎‎ (ES) to Madrid bus From Cáceres‎‎ (ES) to Madrid bus
Bus Laredo - Santander Bus Laredo - Santander
From Llanes to Santander bus From Llanes to Santander bus
Bus from Barreda to Santander Bus from Barreda to Santander
Bus from Seville to Santander Bus from Seville to Santander
Popular Airport Shuttles to Madrid and to Santander
CheckMyBus › Buses in Spain › Bus to Madrid › Bus to Santander

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