Bus Lafayette, IN to Knoxville, TN: Compare prices and save money

Compare all timetables for the bus from Lafayette, IN to Knoxville, TN

Here is a selection of the cheapest bus trips from the schedule from Lafayette, IN to Knoxville, TN from various bus operators like Greyhound US or FlixBus for the next days.

today

$79

tomorrow

Monday

Tuesday

Wednesday

$74

Thursday

$79

Friday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	24h 45m	5:00 PM	Lafayette, IN	Next to CityBus Center	5:45 PM	Knoxville, TN	Greyhound Bus Station	Economy	$79	A Bus from Greyhound US goes from Next to CityBus Center, Lafayette, IN (USA) at 10/24/2026 5:00:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 10/25/2026 5:45:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 24h 45m
FlixBus	24h 15m	9:35 PM	Lafayette, IN	Next to CityBus Center	9:50 PM	Knoxville, TN	Greyhound Bus Station	Economy	$79	A Bus from FlixBus goes from Next to CityBus Center, Lafayette, IN (USA) at 10/24/2026 9:35:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 10/25/2026 9:50:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 24h 15m
Greyhound US	13h 0m	9:30 AM	Lafayette, IN	Next to CityBus Center	10:30 PM	Knoxville, TN	Greyhound Bus Station	Economy	$80	A Bus from Greyhound US goes from Next to CityBus Center, Lafayette, IN (USA) at 10/24/2026 9:30:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 10/24/2026 10:30:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 13h 0m
Greyhound US	24h 45m	7:05 PM	Lafayette, IN	Next to CityBus Center	7:50 PM	Knoxville, TN	Greyhound Bus Station	Economy	$83	A Bus from Greyhound US goes from Next to CityBus Center, Lafayette, IN (USA) at 10/24/2026 7:05:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 10/25/2026 7:50:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 24h 45m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	13h 0m	9:30 AM	Lafayette, IN	Next to CityBus Center	10:30 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$74	A Bus from Greyhound US goes from Next to CityBus Center, Lafayette, IN (USA) at 10/28/2026 9:30:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 10/28/2026 10:30:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 13h 0m
Greyhound US	24h 45m	5:00 PM	Lafayette, IN	Next to CityBus Center	5:45 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$75	A Bus from Greyhound US goes from Next to CityBus Center, Lafayette, IN (USA) at 10/28/2026 5:00:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 10/29/2026 5:45:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 24h 45m
Greyhound US	24h 45m	7:05 PM	Lafayette, IN	Next to CityBus Center	7:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$90	A Bus from Greyhound US goes from Next to CityBus Center, Lafayette, IN (USA) at 10/28/2026 7:05:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 10/29/2026 7:50:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 24h 45m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	24h 45m	5:00 PM	Lafayette, IN	Next to CityBus Center	5:45 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$79	A Bus from Greyhound US goes from Next to CityBus Center, Lafayette, IN (USA) at 10/29/2026 5:00:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 10/30/2026 5:45:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 24h 45m
Greyhound US	13h 0m	9:30 AM	Lafayette, IN	Next to CityBus Center	10:30 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$80	A Bus from Greyhound US goes from Next to CityBus Center, Lafayette, IN (USA) at 10/29/2026 9:30:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 10/29/2026 10:30:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 13h 0m
FlixBus	24h 15m	9:35 PM	Lafayette, IN	Next to CityBus Center	9:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$84	A Bus from FlixBus goes from Next to CityBus Center, Lafayette, IN (USA) at 10/29/2026 9:35:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 10/30/2026 9:50:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 24h 15m
Greyhound US	24h 45m	7:05 PM	Lafayette, IN	Next to CityBus Center	7:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$89	A Bus from Greyhound US goes from Next to CityBus Center, Lafayette, IN (USA) at 10/29/2026 7:05:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 10/30/2026 7:50:00 PM. 50 Economy ticket for $89 per person are available. Travel duration is 24h 45m

Best Price Offer: The price for the cheapest bus from Lafayette, IN to Knoxville, TN is $67 on 11/10/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Lafayette, IN and Knoxville, TN

See here how frequent the connections between Lafayette, IN and Knoxville, TN are, during different times and days of the week.

Thursday is the busiest day, with more than 8 daily buses from Lafayette, IN to Knoxville, TN. Saturday has instead the fewest connections, with only 4 daily coaches between Lafayette, IN and Knoxville, TN.

The busiest time of the day is the Evening, with 8 buses from Lafayette, IN to Knoxville, TN, while Morning sees the fewest connections between Lafayette, IN and Knoxville, TN, with 5 offers.

Facts about the bus from Lafayette, IN to Knoxville, TN

Compare all providers like Greyhound US and FlixBus that travel 6 times every day by bus from Lafayette, IN to Knoxville, TN in one click! Book your bus ticket from Lafayette, IN to Knoxville, TN starting from $67!

Cheapest Bus	$67
Fastest Bus	13h 0m
Earliest Bus	9:30 AM
Latest Bus	9:35 PM
Daily Bus Routes	6 Ø
Distance	347.2 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Lafayette, IN to Knoxville, TN

Every day, 6 buses from 2 bus companies leave Lafayette, IN for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/24/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 10/18

Monday 10/19

Tuesday 10/20

Wednesday 10/21

Thursday 10/22

Friday 10/23

Saturday 10/24

$79

Sunday 10/25

Monday 10/26

Tuesday 10/27

Wednesday 10/28

$78

Thursday 10/29

$83

Friday 10/30

Saturday 10/31

$84

Sunday 11/01

Monday 11/02

Tuesday 11/03

Wednesday 11/04

Thursday 11/05

$75

Friday 11/06

$78

Saturday 11/07

$69

Sunday 11/08

$69

Monday 11/09

$68

Tuesday 11/10

$67

Wednesday 11/11

Thursday 11/12

$84

Friday 11/13

Saturday 11/14

The cheapest time to travel from Lafayette, IN to Knoxville, TN

See here on which day and which time of the day you can find the cheapest bus ticket from Lafayette, IN to Knoxville, TN, for the next 30 days.

With a price starting from $69, Saturday is the cheapest day for a bus from Lafayette, IN to Knoxville, TN. Thursday instead is the most expensive day with prices starting from $75.

Morning is the cheapest day time for bus tickets from Lafayette, IN to Knoxville, TN, with $74. Evening is the most expensive time of the day with prices starting from $79.

How to save money travelling from Lafayette, IN to Knoxville, TN

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Lafayette, IN to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Lafayette, IN to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Lafayette, IN to Knoxville, TN are also emptier.

All bus stations and stops in Lafayette, IN and Knoxville, TN

In the map below, you can see where to find all bus stations in Lafayette, IN and Knoxville, TN.

Next to CityBus Center

N 3Rd St (between Brown and North Street) 410

Bus Stop

West Lafayette, IN

N Grant St 103-173

Progress Drive / Roy Meeks Way

Kingston Pike

Kingston Pike 6927

Knoxville Area Transit Bus Stop

Knoxville Area Transit Bus Stop Knoxville Area Transit Bus Stop

Walker Springs Plaza Shopping Center

Kingston Pike 8509

Transit Center

E Church Ave 301

Greyhound Bus Station

E Magnolia Ave 100

Service and Comfort on the bus from Lafayette, IN to Knoxville, TN

Want to know which seat classes are available on the buses from Lafayette, IN to Knoxville, TN? Or which bus companies serve the route Lafayette, IN to Knoxville, TN? Below you will find answers to your questions.

FAQs about the Lafayette, IN to Knoxville, TN bus

How much does a Lafayette, IN Knoxville, TN bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $67 and takes 13h 0m to reach Knoxville, TN. Compare offers to save money!

How much could I save by comparing buses from Lafayette, IN to Knoxville, TN?

This route is offered by 2 companies with a range of ticket prices between $67 and $94. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.

On average, how many connections are available from Lafayette, IN to Knoxville, TN each day?

Every day, the Lafayette, IN to Knoxville, TN bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Lafayette, IN to Knoxville, TN take?

The fastest bus from Lafayette, IN to Knoxville, TN is offered by Greyhound US and takes 13h 0m. Bus tickets for this connection cost $80. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Lafayette, IN to Knoxville, TN?

The earliest bus arriving in Knoxville, TN from Lafayette, IN starts at 9:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Lafayette, IN to Knoxville, TN?

The latest bus trip departing from Lafayette, IN for Knoxville, TN starts at 9:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Lafayette, IN Knoxville, TN route?

When traveling by bus from Lafayette, IN to Knoxville, TN, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Lafayette, IN and Knoxville, TN?

You can check all the direct connections between Lafayette, IN and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Lafayette, IN to Knoxville, TN bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Lafayette, IN Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Lafayette, IN Knoxville, TN bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Lafayette, IN to Knoxville, TN on your planned travel date.

How does CheckMyBus find the best bus deals from Lafayette, IN to Knoxville, TN?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Lafayette, IN and Knoxville, TN. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Lafayette, IN to Knoxville, TN?

Prices and availability for 6 trips between Lafayette, IN and Knoxville, TN change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Lafayette, IN to Knoxville, TN

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Lafayette, IN and to Knoxville, TN

Here’s an overview of the most popular bus routes to Lafayette, IN and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!