Bus Knoxville, TN to Houston: Compare prices and save money

Compare all timetables for the bus from Knoxville, TN to Houston

Here is a selection of the cheapest bus trips from the schedule from Knoxville, TN to Houston from various bus operators like Greyhound US for the next days.

today

$128

tomorrow

$123

Monday

$133

Tuesday

$130

Wednesday

$130

Thursday

$127

Friday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	24h 10m	5:55 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	5:05 PM	Houston	Harrisburg Blvd Station	Economy	$128	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/24/2026 5:55:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 10/25/2026 5:05:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 24h 10m
Greyhound US	41h 40m	10:00 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	2:40 PM	Houston	SW Agencia Autobuses	Economy	$128	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/24/2026 10:00:00 PM to SW Agencia Autobuses, Houston (USA) arriving at 10/26/2026 2:40:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 41h 40m
Greyhound US	27h 20m	5:55 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	8:15 PM	Houston	SW Agencia Autobuses	Economy	$129	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/24/2026 5:55:00 PM to SW Agencia Autobuses, Houston (USA) arriving at 10/25/2026 8:15:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 27h 20m
Greyhound US	26h 0m	5:55 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	6:55 PM	Houston	Downtown Houston	Economy	$129	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/24/2026 5:55:00 PM to Downtown Houston, Houston (USA) arriving at 10/25/2026 6:55:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 26h 0m
Greyhound US	22h 55m	8:00 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	5:55 PM	Houston	Harrisburg Blvd Station	Economy	$130	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/24/2026 8:00:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 10/25/2026 5:55:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 22h 55m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	24h 10m	5:55 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	5:05 PM	Houston	Harrisburg Blvd Station	Economy	$123	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/25/2026 5:55:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 10/26/2026 5:05:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 24h 10m
Greyhound US	39h 0m	10:00 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	12:00 PM	Houston	Downtown Houston	Economy	$123	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/25/2026 10:00:00 PM to Downtown Houston, Houston (USA) arriving at 10/27/2026 12:00:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 39h 0m
Greyhound US	26h 0m	5:55 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	6:55 PM	Houston	Downtown Houston	Economy	$124	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/25/2026 5:55:00 PM to Downtown Houston, Houston (USA) arriving at 10/26/2026 6:55:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 26h 0m
Greyhound US	39h 40m	10:00 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	12:40 PM	Houston	Harrisburg Blvd Station	Economy	$125	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/25/2026 10:00:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 10/27/2026 12:40:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 39h 40m
Greyhound US	42h 35m	10:00 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	3:35 PM	Houston	SW Agencia Autobuses	Economy	$127	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/25/2026 10:00:00 PM to SW Agencia Autobuses, Houston (USA) arriving at 10/27/2026 3:35:00 PM. 50 Economy ticket for $127 per person are available. Travel duration is 42h 35m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	26h 0m	5:55 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	6:55 PM	Houston	Downtown Houston	Economy	$133	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/26/2026 5:55:00 PM to Downtown Houston, Houston (USA) arriving at 10/27/2026 6:55:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 26h 0m
Greyhound US	24h 15m	8:00 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	7:15 PM	Houston	Downtown Houston	Economy	$133	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/26/2026 8:00:00 PM to Downtown Houston, Houston (USA) arriving at 10/27/2026 7:15:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 24h 15m
Greyhound US	24h 10m	5:55 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	5:05 PM	Houston	Harrisburg Blvd Station	Economy	$133	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/26/2026 5:55:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 10/27/2026 5:05:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 24h 10m
Greyhound US	22h 55m	8:00 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	5:55 PM	Houston	Harrisburg Blvd Station	Economy	$133	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/26/2026 8:00:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 10/27/2026 5:55:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 22h 55m
Greyhound US	39h 0m	10:00 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	12:00 PM	Houston	Downtown Houston	Economy	$135	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/26/2026 10:00:00 PM to Downtown Houston, Houston (USA) arriving at 10/28/2026 12:00:00 PM. 50 Economy ticket for $135 per person are available. Travel duration is 39h 0m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	24h 10m	5:55 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	5:05 PM	Houston	Harrisburg Blvd Station	Economy	$130	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/27/2026 5:55:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 10/28/2026 5:05:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 24h 10m
Greyhound US	22h 55m	8:00 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	5:55 PM	Houston	Harrisburg Blvd Station	Economy	$130	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/27/2026 8:00:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 10/28/2026 5:55:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 22h 55m
Greyhound US	26h 0m	8:00 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	9:00 PM	Houston	Downtown Houston	Economy	$130	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/27/2026 8:00:00 PM to Downtown Houston, Houston (USA) arriving at 10/28/2026 9:00:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 26h 0m
Greyhound US	40h 40m	10:00 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	1:40 PM	Houston	SW Agencia Autobuses	Economy	$163	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/27/2026 10:00:00 PM to SW Agencia Autobuses, Houston (USA) arriving at 10/29/2026 1:40:00 PM. 50 Economy ticket for $163 per person are available. Travel duration is 40h 40m
Greyhound US	39h 40m	10:00 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	12:40 PM	Houston	Harrisburg Blvd Station	Economy	$165	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/27/2026 10:00:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 10/29/2026 12:40:00 PM. 50 Economy ticket for $165 per person are available. Travel duration is 39h 40m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	22h 55m	8:00 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	5:55 PM	Houston	Harrisburg Blvd Station	Economy	$130	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/28/2026 8:00:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 10/29/2026 5:55:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 22h 55m
Greyhound US	26h 0m	8:00 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	9:00 PM	Houston	Downtown Houston	Economy	$130	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/28/2026 8:00:00 PM to Downtown Houston, Houston (USA) arriving at 10/29/2026 9:00:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 26h 0m
Greyhound US	40h 40m	10:00 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	1:40 PM	Houston	SW Agencia Autobuses	Economy	$132	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/28/2026 10:00:00 PM to SW Agencia Autobuses, Houston (USA) arriving at 10/30/2026 1:40:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 40h 40m
Greyhound US	24h 10m	5:55 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	5:05 PM	Houston	Harrisburg Blvd Station	Economy	$133	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/28/2026 5:55:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 10/29/2026 5:05:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 24h 10m
Greyhound US	39h 40m	10:00 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	12:40 PM	Houston	Harrisburg Blvd Station	Economy	$134	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/28/2026 10:00:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 10/30/2026 12:40:00 PM. 50 Economy ticket for $134 per person are available. Travel duration is 39h 40m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	24h 10m	5:55 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	5:05 PM	Houston	Harrisburg Blvd Station	Economy	$127	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/29/2026 5:55:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 10/30/2026 5:05:00 PM. 50 Economy ticket for $127 per person are available. Travel duration is 24h 10m
Greyhound US	22h 55m	8:00 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	5:55 PM	Houston	Harrisburg Blvd Station	Economy	$127	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/29/2026 8:00:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 10/30/2026 5:55:00 PM. 50 Economy ticket for $127 per person are available. Travel duration is 22h 55m
Greyhound US	24h 15m	8:00 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	7:15 PM	Houston	Downtown Houston	Economy	$127	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/29/2026 8:00:00 PM to Downtown Houston, Houston (USA) arriving at 10/30/2026 7:15:00 PM. 50 Economy ticket for $127 per person are available. Travel duration is 24h 15m
Greyhound US	39h 0m	10:00 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	12:00 PM	Houston	Downtown Houston	Economy	$128	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/29/2026 10:00:00 PM to Downtown Houston, Houston (USA) arriving at 10/31/2026 12:00:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 39h 0m
Greyhound US	27h 20m	5:55 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	8:15 PM	Houston	SW Agencia Autobuses	Economy	$129	A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 10/29/2026 5:55:00 PM to SW Agencia Autobuses, Houston (USA) arriving at 10/30/2026 8:15:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 27h 20m

Best Price Offer: The price for the cheapest bus from Knoxville, TN to Houston is $108 on 11/5/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Knoxville, TN and Houston

See here how frequent the connections between Knoxville, TN and Houston are, during different times and days of the week.

Thursday is the busiest day, with more than 16 daily buses from Knoxville, TN to Houston. Tuesday has instead the fewest connections, with only 5 daily coaches between Knoxville, TN and Houston.

The busiest time of the day is the Evening, with 49 buses from Knoxville, TN to Houston, while Afternoon sees the fewest connections between Knoxville, TN and Houston, with 22 offers.

Facts about the bus from Knoxville, TN to Houston

Compare all providers like Greyhound US that travel 11 times every day by bus from Knoxville, TN to Houston in one click! Book your bus ticket from Knoxville, TN to Houston starting from $108!

Cheapest Bus	$108
Fastest Bus	21h 55m
Earliest Bus	5:55 PM
Latest Bus	10:00 PM
Daily Bus Routes	11 Ø
Distance	791.0 miles
Bus Companies	Greyhound US

Cheapest bus connections from Knoxville, TN to Houston

Every day, 11 buses from 1 bus companies leave Knoxville, TN for Houston: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/24/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 10/18

Monday 10/19

Tuesday 10/20

Wednesday 10/21

Thursday 10/22

Friday 10/23

Saturday 10/24

$131

Sunday 10/25

$127

Monday 10/26

$133

Tuesday 10/27

$130

Wednesday 10/28

$130

Thursday 10/29

$131

Friday 10/30

Saturday 10/31

$127

Sunday 11/01

Monday 11/02

$111

Tuesday 11/03

$112

Wednesday 11/04

$115

Thursday 11/05

$108

Friday 11/06

$114

Saturday 11/07

Sunday 11/08

$109

Monday 11/09

$111

Tuesday 11/10

Wednesday 11/11

$108

Thursday 11/12

$118

Friday 11/13

$142

Saturday 11/14

The cheapest time to travel from Knoxville, TN to Houston

See here on which day and which time of the day you can find the cheapest bus ticket from Knoxville, TN to Houston, for the next 30 days.

With a price starting from $108, Wednesday is the cheapest day for a bus from Knoxville, TN to Houston. Saturday instead is the most expensive day with prices starting from $122.

Evening is the cheapest day time for bus tickets from Knoxville, TN to Houston, with $123. Afternoon is the most expensive time of the day with prices starting from $123.

How to save money travelling from Knoxville, TN to Houston

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Knoxville, TN to Houston in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Knoxville, TN to Houston, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Knoxville, TN to Houston are also emptier.

Beloved bus companies from Knoxville, TN to Houston

These are the most booked bus companies between Knoxville, TN to Houston from our users.

Greyhound US from Knoxville, TN to Houston

Here you will find the key facts about the Greyhound US bus route Knoxville, TN to Houston:

Cheapest Price	$123
Fastest Bus	21h 55m
Earliest Bus	5:55 PM
Last Bus	10:00 PM
Daily Connections	11 Ø
Found on	10/19/2026

All bus stations and stops in Knoxville, TN and Houston

In the map below, you can see where to find all bus stations in Knoxville, TN and Houston.

Kingston Pike

Kingston Pike 6927

Knoxville Area Transit Bus Stop

Knoxville Area Transit Bus Stop Knoxville Area Transit Bus Stop

Walker Springs Plaza Shopping Center

Kingston Pike 8509

Transit Center

E Church Ave 301

Greyhound Bus Station

E Magnolia Ave 100

Downtown Houston

Gray St 605

Harrisburg Blvd Station

Harrisburg Blvd 7000

Main Street

Main St 2121

Chase Bank

Milam Street 212

Uptown/Upper Kirby

Southwest Fwy 2525

Service and Comfort on the bus from Knoxville, TN to Houston

Want to know which seat classes are available on the buses from Knoxville, TN to Houston? Or which bus companies serve the route Knoxville, TN to Houston? Below you will find answers to your questions.

FAQs about the Knoxville, TN to Houston bus

How much does a Knoxville, TN Houston bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $108 and takes 38h 0m to reach Houston. Compare offers to save money!

How much could I save by comparing buses from Knoxville, TN to Houston?

This route is offered by 1 companies with a range of ticket prices between $108 and $165. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Houston.

On average, how many connections are available from Knoxville, TN to Houston each day?

Every day, the Knoxville, TN to Houston bus route is served by approximately 11 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Knoxville, TN to Houston take?

The fastest bus from Knoxville, TN to Houston is offered by Greyhound US and takes 21h 55m. Bus tickets for this connection cost $130. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Knoxville, TN to Houston?

The earliest bus arriving in Houston from Knoxville, TN starts at 5:55 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Knoxville, TN to Houston?

The latest bus trip departing from Knoxville, TN for Houston starts at 10:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Knoxville, TN Houston route?

When traveling by bus from Knoxville, TN to Houston, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Knoxville, TN and Houston?

You can check all the direct connections between Knoxville, TN and Houston by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Knoxville, TN to Houston bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Knoxville, TN Houston bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Knoxville, TN Houston bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Knoxville, TN to Houston on your planned travel date.

How does CheckMyBus find the best bus deals from Knoxville, TN to Houston?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 11 daily trips between Knoxville, TN and Houston. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Knoxville, TN to Houston?

Prices and availability for 11 trips between Knoxville, TN and Houston change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Knoxville, TN to Houston

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Knoxville, TN and to Houston

Here’s an overview of the most popular bus routes to Knoxville, TN and to Houston. Simply click on the connection of your choice, and you will find all the details about your bus route!