Which bus from Key West, FL to Orlando, FL is the cheapest?

Compare all bus companies and find the best price: Bus tickets from $41
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Key West, FL to Orlando, FL

Here is a selection of the cheapest bus trips from the schedule from Key West, FL to Orlando, FL from various bus operators like Greyhound US for the next days.

today
tomorrow
$52
Monday
Tuesday
Wednesday
$49
Thursday
$54
Friday

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 10h 15m 10:00 AM Key West, FL Bus Stop 8:15 PM Orlando, FL Bus Station  Economy $52
Greyhound US 9h 45m 1:30 PM Key West, FL Bus Stop 11:15 PM Orlando, FL Bus Station  Economy $56
Greyhound US 9h 10m 1:30 PM Key West, FL Bus Stop 10:40 PM Orlando, FL Florida Mall  Economy $56
Greyhound US 11h 15m 5:00 PM Key West, FL Bus Stop 4:15 AM Orlando, FL Bus Station  Economy $58
Greyhound US 10h 40m 5:00 PM Key West, FL Bus Stop 3:40 AM Orlando, FL Florida Mall  Economy $58

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 12h 40m 10:00 AM Key West, FL Bus Stop 10:40 PM Orlando, FL Florida Mall  Economy $49
Greyhound US 10h 40m 5:00 PM Key West, FL Bus Stop 3:40 AM Orlando, FL Florida Mall  Economy $49
Greyhound US 10h 15m 10:00 AM Key West, FL Bus Stop 8:15 PM Orlando, FL Bus Station  Economy $49
Greyhound US 11h 15m 5:00 PM Key West, FL Bus Stop 4:15 AM Orlando, FL Bus Station  Economy $50

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 10h 15m 10:00 AM Key West, FL Bus Stop 8:15 PM Orlando, FL Bus Station  Economy $54
Greyhound US 11h 15m 5:00 PM Key West, FL Bus Stop 4:15 AM Orlando, FL Bus Station  Economy $57
Greyhound US 10h 40m 5:00 PM Key West, FL Bus Stop 3:40 AM Orlando, FL Florida Mall  Economy $58
  • Did you know that if you travel from Key West, FL to Orlando, FL via Miami Airport, you can save more than $9? You can find the corresponding connections below.
    • Greyhound US
      11h 15m
      0
      5:00 PM
      Key West, FL
      Bus Stop
      9:15 PM
      Miami Airport
      Miami Airport - Terminal J
      0
      Greyhound US
      Economy
      $19
      • Waiting Time 2h 10m
    • Greyhound US
      4h 50m
      0
      11:25 PM
      Miami Airport
      Miami Airport - Intermodal Station
      4:15 AM
      Orlando, FL
      Central Bus Station
      0
      Greyhound US
      Economy
      $26
    Travel time is 1h 0m longer, but you will save $9

Best Price Offer: The price for the cheapest bus from Key West, FL to Orlando, FL is $41 on 9/17/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Key West, FL and Orlando, FL

See here how frequent the connections between Key West, FL and Orlando, FL are, during different times and days of the week.
Sunday is the busiest day, with more than 10 daily buses from Key West, FL to Orlando, FL. Thursday has instead the fewest connections, with only 6 daily coaches between Key West, FL and Orlando, FL.
The busiest time of the day is the Afternoon, with 16 buses from Key West, FL to Orlando, FL, while Morning sees the fewest connections between Key West, FL and Orlando, FL, with 8 offers.

Facts about the bus from Key West, FL to Orlando, FL

Compare all providers like Greyhound US that travel 8 times every day by bus from Key West, FL to Orlando, FL in one click! Book your bus ticket from Key West, FL to Orlando, FL starting from $41!

Cheapest Bus $41
Fastest Bus 9h 10m
Earliest Bus 10:00 AM
Latest Bus 5:00 PM
Daily Bus Routes 8 Ø
Distance 276.6 miles
Bus Companies Greyhound US

Cheapest bus connections from Key West, FL to Orlando, FL

Every day, 8 buses from 1 bus companies leave Key West, FL for Orlando, FL: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 08/29/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 08/23
Monday 08/24
Tuesday 08/25
Wednesday 08/26
Thursday 08/27
Friday 08/28
Saturday 08/29
Sunday 08/30
$52
Monday 08/31
Tuesday 09/01
Wednesday 09/02
$49
Thursday 09/03
$55
Friday 09/04
Saturday 09/05
Sunday 09/06
$61
Monday 09/07
$63
Tuesday 09/08
$49
Wednesday 09/09
$49
Thursday 09/10
$54
Friday 09/11
$49
Saturday 09/12
$55
Sunday 09/13
$55
Monday 09/14
$47
Tuesday 09/15
$42
Wednesday 09/16
$44
Thursday 09/17
$41
Friday 09/18
$51
Saturday 09/19

The cheapest time to travel from Key West, FL to Orlando, FL

See here on which day and which time of the day you can find the cheapest bus ticket from Key West, FL to Orlando, FL, for the next 30 days.
With a price starting from $41, Wednesday is the cheapest day for a bus from Key West, FL to Orlando, FL. Sunday instead is the most expensive day with prices starting from $52.
Morning is the cheapest day time for bus tickets from Key West, FL to Orlando, FL, with $49. Morning is the most expensive time of the day with prices starting from $49.

How to save money travelling from Key West, FL to Orlando, FL

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Key West, FL to Orlando, FL in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Key West, FL to Orlando, FL, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Key West, FL to Orlando, FL are also emptier.

Beloved bus companies from Key West, FL to Orlando, FL

These are the most booked bus companies between Key West, FL to Orlando, FL from our users.

Greyhound US from Key West, FL to Orlando, FL

Greyhound US

Here you will find the key facts about the Greyhound US bus route Key West, FL to Orlando, FL:

Cheapest Price $49
Fastest Bus 9h 10m
Earliest Bus 10:00 AM
Last Bus 5:00 PM
Daily Connections 8 Ø
Found on 8/25/2026

All bus stations and stops in Key West, FL and Orlando, FL

In the map below, you can see where to find all bus stations in Key West, FL and Orlando, FL.

Service and Comfort on the bus from Key West, FL to Orlando, FL

Want to know which seat classes are available on the buses from Key West, FL to Orlando, FL? Or which bus companies serve the route Key West, FL to Orlando, FL? Below you will find answers to your questions.

FAQs about the Key West, FL to Orlando, FL bus

How much does a Key West, FL Orlando, FL bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $41 and takes 12h 40m to reach Orlando, FL. Compare offers to save money!

How much could I save by comparing buses from Key West, FL to Orlando, FL?

This route is offered by 1 companies with a range of ticket prices between $41 and $62. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Orlando, FL.

On average, how many connections are available from Key West, FL to Orlando, FL each day?

Every day, the Key West, FL to Orlando, FL bus route is served by approximately 8 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Key West, FL to Orlando, FL take?

The fastest bus from Key West, FL to Orlando, FL is offered by Greyhound US and takes 9h 10m. Bus tickets for this connection cost $56. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Key West, FL to Orlando, FL?

The earliest bus arriving in Orlando, FL from Key West, FL starts at 10:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Key West, FL to Orlando, FL?

The latest bus trip departing from Key West, FL for Orlando, FL starts at 5:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Key West, FL Orlando, FL route?

When traveling by bus from Key West, FL to Orlando, FL, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Key West, FL and Orlando, FL?

You can check all the direct connections between Key West, FL and Orlando, FL by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Key West, FL to Orlando, FL bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Key West, FL Orlando, FL bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Key West, FL Orlando, FL bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Key West, FL to Orlando, FL on your planned travel date.

How does CheckMyBus find the best bus deals from Key West, FL to Orlando, FL?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 8 daily trips between Key West, FL and Orlando, FL. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Key West, FL to Orlando, FL?

Prices and availability for 8 trips between Key West, FL and Orlando, FL change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Key West, FL to Orlando, FL

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Key West, FL and to Orlando, FL

Here’s an overview of the most popular bus routes to Key West, FL and to Orlando, FL. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus from Jacksonville, FL to Key West, FL Bus from Jacksonville, FL to Key West, FL
Buses from Melbourne, FL to Key West, FL Buses from Melbourne, FL to Key West, FL
Bus New York to Key West, FL Bus New York to Key West, FL
From Hartford, CT to Key West, FL bus From Hartford, CT to Key West, FL bus
From York, PA to Orlando, FL bus From York, PA to Orlando, FL bus
Bus Binghamton, NY to Orlando, FL Bus Binghamton, NY to Orlando, FL
Bus to Orlando, FL from Monroe, LA Bus to Orlando, FL from Monroe, LA
From Louisville, KY to Orlando, FL bus From Louisville, KY to Orlando, FL bus
Popular Airport Shuttles to Key West, FL and to Orlando, FL
CheckMyBus › Buses in USA › Bus to Key West, FL › Bus to Orlando, FL

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.