Bus Florence to Lyon - Compare all Companies

Compare all timetables for the bus from Florence to Lyon

Here is a selection of the cheapest bus trips from the schedule from Florence to Lyon from various bus operators like FlixBus, Itabus or BlaBlaCar Bus for the next days.

today

$58

tomorrow

$22

Friday

$37

Saturday

$29

Sunday

$34

Monday

$39

Tuesday

$59

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	11h 15m	12:30 PM	Florence	Villa Costanza Bus Station	11:45 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$58	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 10/21/2026 12:30:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/21/2026 11:45:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 11h 15m
Itabus	12h 35m	11:55 AM	Florence	Villa Costanza Bus Station	12:30 AM	Lyon	Perrache Bus Stop	Premium Economy	$59	A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 10/21/2026 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 10/22/2026 12:30:00 AM. 50 Premium Economy ticket for $59 per person are available. Travel duration is 12h 35m
FlixBus	11h 45m	6:45 PM	Florence	Villa Costanza Bus Station	6:30 AM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$67	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 10/21/2026 6:45:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/22/2026 6:30:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 11h 45m
FlixBus	11h 40m	9:05 PM	Florence	Villa Costanza Bus Station	8:45 AM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$72	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 10/21/2026 9:05:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/22/2026 8:45:00 AM. 50 Economy ticket for $72 per person are available. Travel duration is 11h 40m

Did you know that if you travel from Florence to Lyon via Turin, you can save more than $29? You can find the corresponding connections below.
- FlixBus
  
  15h 0m
  
  0
  
  11:15 PM
  
  Florence
  Piazzale Montelungo Bus Stop
  
  7:25 AM
  
  Turin
  Central Bus Station
  
  0
  
  Economy
  
  $14
  
  A Bus from FlixBus goes from Piazzale Montelungo Bus Stop, Florence (Italy) at 10/22/2026 11:15:00 PM to Central Bus Station, Turin (Italy) arriving at 10/23/2026 7:25:00 AM. 50 Economy ticket for $14 per person are available. Travel duration is 8h 10m
- Union Ivkoni
  
  5h 45m
  
  0
  
  8:30 AM
  
  Turin
  Central Bus Station
  
  2:15 PM
  
  Lyon
  Lyon Avenue Tony Garnier Bus Stop
  
  0
  
  Economy
  
  $15
  
  A Bus from Union Ivkoni goes from Central Bus Station, Turin (Italy) at 10/23/2026 8:30:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/23/2026 2:15:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 5h 45m
Travel time is 3h 45m longer, but you will save $29

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	11h 10m	10:20 AM	Florence	Villa Costanza Bus Station	9:30 PM	Lyon	Perrache Bus Stop	Premium Economy	$22	A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 10/22/2026 10:20:00 AM to Perrache Bus Stop, Lyon (France) arriving at 10/22/2026 9:30:00 PM. 50 Premium Economy ticket for $22 per person are available. Travel duration is 11h 10m
FlixBus	11h 45m	6:45 PM	Florence	Villa Costanza Bus Station	6:30 AM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$55	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 10/22/2026 6:45:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/23/2026 6:30:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 11h 45m
FlixBus	11h 15m	12:30 PM	Florence	Villa Costanza Bus Station	11:45 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$56	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 10/22/2026 12:30:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/22/2026 11:45:00 PM. 50 Economy ticket for $56 per person are available. Travel duration is 11h 15m
FlixBus	10h 40m	12:00 PM	Florence	Villa Costanza Bus Station	10:40 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$62	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 10/22/2026 12:00:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/22/2026 10:40:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 10h 40m
Itabus	11h 55m	1:05 AM	Florence	Villa Costanza Bus Station	1:00 PM	Lyon	Perrache Bus Stop	Premium Economy	$67	A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 10/22/2026 1:05:00 AM to Perrache Bus Stop, Lyon (France) arriving at 10/22/2026 1:00:00 PM. 50 Premium Economy ticket for $67 per person are available. Travel duration is 11h 55m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	11h 10m	10:20 AM	Florence	Villa Costanza Bus Station	9:30 PM	Lyon	Perrache Bus Stop	Premium Economy	$37	A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 10/23/2026 10:20:00 AM to Perrache Bus Stop, Lyon (France) arriving at 10/23/2026 9:30:00 PM. 50 Premium Economy ticket for $37 per person are available. Travel duration is 11h 10m
BlaBlaCar Bus	11h 5m	2:15 PM	Florence	Villa Costanza Bus Station	1:20 AM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$38	A Bus from BlaBlaCar Bus goes from Villa Costanza Bus Station, Florence (Italy) at 10/23/2026 2:15:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/24/2026 1:20:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 11h 5m
FlixBus	10h 40m	12:00 PM	Florence	Villa Costanza Bus Station	10:40 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$56	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 10/23/2026 12:00:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/23/2026 10:40:00 PM. 50 Economy ticket for $56 per person are available. Travel duration is 10h 40m
FlixBus	11h 45m	6:45 PM	Florence	Villa Costanza Bus Station	6:30 AM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$65	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 10/23/2026 6:45:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/24/2026 6:30:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 11h 45m
Itabus	11h 55m	1:05 AM	Florence	Villa Costanza Bus Station	1:00 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$73	A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 10/23/2026 1:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/23/2026 1:00:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 11h 55m

Did you know that if you travel from Florence to Lyon via Scandicci, you can save more than $-5? You will find the corresponding connections below.
- 11h 10m
  
  Florence
  
  3 mi
  
  10:20 AM
  
  Scandicci
  Bus Stop
  
  9:30 PM
  
  Lyon
  Perrache Bus Stop
  
  0 mi
  
  Economy
  
  $42
  
  A Bus from goes from Bus Stop, Scandicci (Italy) at 10/23/2026 10:20:00 AM to Perrache Bus Stop, Lyon (France) arriving at 10/23/2026 9:30:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 11h 10m
Did you know that if you travel from Florence to Lyon via Turin, you can save more than $11? You can find the corresponding connections below.
- FlixBus
  
  13h 45m
  
  0
  
  11:15 PM
  
  Florence
  Piazzale Montelungo Bus Stop
  
  6:25 AM
  
  Turin
  Central Bus Station
  
  0
  
  Economy
  
  $10
  
  A Bus from FlixBus goes from Piazzale Montelungo Bus Stop, Florence (Italy) at 10/24/2026 11:15:00 PM to Central Bus Station, Turin (Italy) arriving at 10/25/2026 6:25:00 AM. 50 Economy ticket for $10 per person are available. Travel duration is 8h 10m
- Itabus
  
  4h 30m
  
  0
  
  7:30 AM
  
  Turin
  Central Bus Station
  
  12:00 PM
  
  Lyon
  Perrache Bus Stop
  
  0
  
  Premium Economy
  
  $17
  
  A Bus from Itabus goes from Central Bus Station, Turin (Italy) at 10/25/2026 7:30:00 AM to Perrache Bus Stop, Lyon (France) arriving at 10/25/2026 12:00:00 PM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 4h 30m
Travel time is 3h 5m longer, but you will save $11

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	11h 10m	10:20 AM	Florence	Villa Costanza Bus Station	9:30 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Premium Economy	$29	A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 10/24/2026 10:20:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/24/2026 9:30:00 PM. 50 Premium Economy ticket for $29 per person are available. Travel duration is 11h 10m
Itabus	12h 35m	11:55 AM	Florence	Villa Costanza Bus Station	12:30 AM	Lyon	Perrache Bus Stop	Premium Economy	$45	A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 10/24/2026 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 10/25/2026 12:30:00 AM. 50 Premium Economy ticket for $45 per person are available. Travel duration is 12h 35m
BlaBlaCar Bus	11h 5m	2:15 PM	Florence	Villa Costanza Bus Station	1:20 AM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$48	A Bus from BlaBlaCar Bus goes from Villa Costanza Bus Station, Florence (Italy) at 10/24/2026 2:15:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/25/2026 1:20:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 11h 5m
FlixBus	10h 40m	12:00 PM	Florence	Villa Costanza Bus Station	10:40 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$62	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 10/24/2026 12:00:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/24/2026 10:40:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 10h 40m
FlixBus	11h 45m	6:45 PM	Florence	Villa Costanza Bus Station	5:30 AM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$67	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 10/24/2026 6:45:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/25/2026 5:30:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 11h 45m

Did you know that if you travel from Florence to Lyon via Turin, you can save more than $3? You can find the corresponding connections below.
- FlixBus
  
  13h 45m
  
  0
  
  11:15 PM
  
  Florence
  Piazzale Montelungo Bus Stop
  
  6:25 AM
  
  Turin
  Central Bus Station
  
  0
  
  Economy
  
  $10
  
  A Bus from FlixBus goes from Piazzale Montelungo Bus Stop, Florence (Italy) at 10/24/2026 11:15:00 PM to Central Bus Station, Turin (Italy) arriving at 10/25/2026 6:25:00 AM. 50 Economy ticket for $10 per person are available. Travel duration is 8h 10m
- Itabus
  
  4h 30m
  
  0
  
  7:30 AM
  
  Turin
  Central Bus Station
  
  12:00 PM
  
  Lyon
  Perrache Bus Stop
  
  0
  
  Premium Economy
  
  $17
  
  A Bus from Itabus goes from Central Bus Station, Turin (Italy) at 10/25/2026 7:30:00 AM to Perrache Bus Stop, Lyon (France) arriving at 10/25/2026 12:00:00 PM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 4h 30m
Travel time is 3h 5m longer, but you will save $3

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	11h 10m	10:20 AM	Florence	Villa Costanza Bus Station	9:30 PM	Lyon	Perrache Bus Stop	Premium Economy	$34	A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 10/25/2026 10:20:00 AM to Perrache Bus Stop, Lyon (France) arriving at 10/25/2026 9:30:00 PM. 50 Premium Economy ticket for $34 per person are available. Travel duration is 11h 10m
BlaBlaCar Bus	11h 5m	2:15 PM	Florence	Villa Costanza Bus Station	1:20 AM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$38	A Bus from BlaBlaCar Bus goes from Villa Costanza Bus Station, Florence (Italy) at 10/25/2026 2:15:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/26/2026 1:20:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 11h 5m
Itabus	11h 55m	1:05 AM	Florence	Villa Costanza Bus Station	12:00 PM	Lyon	Perrache Bus Stop	Premium Economy	$67	A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 10/25/2026 1:05:00 AM to Perrache Bus Stop, Lyon (France) arriving at 10/25/2026 12:00:00 PM. 50 Premium Economy ticket for $67 per person are available. Travel duration is 11h 55m
FlixBus	11h 45m	6:45 PM	Florence	Villa Costanza Bus Station	6:30 AM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$83	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 10/25/2026 6:45:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/26/2026 6:30:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 11h 45m
FlixBus	10h 40m	7:30 AM	Florence	Villa Costanza Bus Station	6:10 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$88	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 10/25/2026 7:30:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/25/2026 6:10:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 10h 40m

Did you know that if you travel from Florence to Lyon via Turin, you can save more than $8? You can find the corresponding connections below.
- FlixBus
  
  13h 45m
  
  0
  
  11:15 PM
  
  Florence
  Piazzale Montelungo Bus Stop
  
  6:25 AM
  
  Turin
  Central Bus Station
  
  0
  
  Economy
  
  $10
  
  A Bus from FlixBus goes from Piazzale Montelungo Bus Stop, Florence (Italy) at 10/24/2026 11:15:00 PM to Central Bus Station, Turin (Italy) arriving at 10/25/2026 6:25:00 AM. 50 Economy ticket for $10 per person are available. Travel duration is 8h 10m
- Itabus
  
  4h 30m
  
  0
  
  7:30 AM
  
  Turin
  Central Bus Station
  
  12:00 PM
  
  Lyon
  Perrache Bus Stop
  
  0
  
  Premium Economy
  
  $17
  
  A Bus from Itabus goes from Central Bus Station, Turin (Italy) at 10/25/2026 7:30:00 AM to Perrache Bus Stop, Lyon (France) arriving at 10/25/2026 12:00:00 PM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 4h 30m
Travel time is 3h 5m longer, but you will save $8

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	12h 35m	11:55 AM	Florence	Villa Costanza Bus Station	12:30 AM	Lyon	Perrache Bus Stop	Premium Economy	$39	A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 10/26/2026 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 10/27/2026 12:30:00 AM. 50 Premium Economy ticket for $39 per person are available. Travel duration is 12h 35m
FlixBus	10h 40m	12:00 PM	Florence	Villa Costanza Bus Station	10:40 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$56	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 10/26/2026 12:00:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/26/2026 10:40:00 PM. 50 Economy ticket for $56 per person are available. Travel duration is 10h 40m
FlixBus	11h 45m	6:45 PM	Florence	Villa Costanza Bus Station	6:30 AM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$65	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 10/26/2026 6:45:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/27/2026 6:30:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 11h 45m
FlixBus	10h 40m	7:30 AM	Florence	Villa Costanza Bus Station	6:10 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$70	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 10/26/2026 7:30:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/26/2026 6:10:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 10h 40m
Itabus	11h 55m	1:05 AM	Florence	Villa Costanza Bus Station	1:00 PM	Lyon	Perrache Bus Stop	Premium Economy	$79	A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 10/26/2026 1:05:00 AM to Perrache Bus Stop, Lyon (France) arriving at 10/26/2026 1:00:00 PM. 50 Premium Economy ticket for $79 per person are available. Travel duration is 11h 55m

Did you know that if you travel from Florence to Lyon via Turin, you can save more than $13? You can find the corresponding connections below.
- FlixBus
  
  13h 45m
  
  0
  
  11:15 PM
  
  Florence
  Piazzale Montelungo Bus Stop
  
  6:25 AM
  
  Turin
  Central Bus Station
  
  0
  
  Economy
  
  $10
  
  A Bus from FlixBus goes from Piazzale Montelungo Bus Stop, Florence (Italy) at 10/24/2026 11:15:00 PM to Central Bus Station, Turin (Italy) arriving at 10/25/2026 6:25:00 AM. 50 Economy ticket for $10 per person are available. Travel duration is 8h 10m
- Itabus
  
  4h 30m
  
  0
  
  7:30 AM
  
  Turin
  Central Bus Station
  
  12:00 PM
  
  Lyon
  Perrache Bus Stop
  
  0
  
  Premium Economy
  
  $17
  
  A Bus from Itabus goes from Central Bus Station, Turin (Italy) at 10/25/2026 7:30:00 AM to Perrache Bus Stop, Lyon (France) arriving at 10/25/2026 12:00:00 PM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 4h 30m
Travel time is 3h 5m longer, but you will save $13

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	12h 35m	11:55 AM	Florence	Villa Costanza Bus Station	12:30 AM	Lyon	Perrache Bus Stop	Premium Economy	$59	A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 10/27/2026 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 10/28/2026 12:30:00 AM. 50 Premium Economy ticket for $59 per person are available. Travel duration is 12h 35m
FlixBus	10h 40m	7:30 AM	Florence	Villa Costanza Bus Station	6:10 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$67	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 10/27/2026 7:30:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/27/2026 6:10:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 10h 40m
Itabus	11h 55m	1:05 AM	Florence	Villa Costanza Bus Station	1:00 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$73	A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 10/27/2026 1:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/27/2026 1:00:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 11h 55m
FlixBus	12h 20m	1:50 AM	Florence	Villa Costanza Bus Station	2:10 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$80	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 10/27/2026 1:50:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/27/2026 2:10:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 12h 20m
FlixBus	11h 10m	4:45 PM	Florence	Villa Costanza Bus Station	3:55 AM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$81	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 10/27/2026 4:45:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/28/2026 3:55:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 11h 10m

Did you know that if you travel from Florence to Lyon via Turin, you can save more than $33? You can find the corresponding connections below.
- FlixBus
  
  13h 45m
  
  0
  
  11:15 PM
  
  Florence
  Piazzale Montelungo Bus Stop
  
  6:25 AM
  
  Turin
  Central Bus Station
  
  0
  
  Economy
  
  $10
  
  A Bus from FlixBus goes from Piazzale Montelungo Bus Stop, Florence (Italy) at 10/24/2026 11:15:00 PM to Central Bus Station, Turin (Italy) arriving at 10/25/2026 6:25:00 AM. 50 Economy ticket for $10 per person are available. Travel duration is 8h 10m
- Itabus
  
  4h 30m
  
  0
  
  7:30 AM
  
  Turin
  Central Bus Station
  
  12:00 PM
  
  Lyon
  Perrache Bus Stop
  
  0
  
  Premium Economy
  
  $17
  
  A Bus from Itabus goes from Central Bus Station, Turin (Italy) at 10/25/2026 7:30:00 AM to Perrache Bus Stop, Lyon (France) arriving at 10/25/2026 12:00:00 PM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 4h 30m
Travel time is 3h 5m longer, but you will save $33

Best Price Offer: The price for the cheapest bus from Florence to Lyon is $22 on 10/22/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Florence and Lyon

See here how frequent the connections between Florence and Lyon are, during different times and days of the week.

Sunday is the busiest day, with more than 24 daily buses from Florence to Lyon. Wednesday has instead the fewest connections, with only 8 daily coaches between Florence and Lyon.

The busiest time of the day is the Night, with 51 buses from Florence to Lyon, while Evening sees the fewest connections between Florence and Lyon, with 20 offers.

Facts about the bus from Florence to Lyon

Compare all providers like FlixBus, Itabus and BlaBlaCar Bus that travel 19 times every day by bus from Florence to Lyon in one click! Book your bus ticket from Florence to Lyon starting from $22!

Cheapest Bus	$22
Fastest Bus	10h 40m
Earliest Bus	11:55 AM
Latest Bus	11:40 PM
Daily Bus Routes	19 Ø
Distance	343.2 miles
Bus Companies	FlixBus, Itabus and BlaBlaCar Bus

Cheapest bus connections from Florence to Lyon

Every day, 19 buses from 3 bus companies leave Florence for Lyon: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/21/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 10/18

Monday 10/19

Tuesday 10/20

Wednesday 10/21

$48

Thursday 10/22

$22

Friday 10/23

$37

Saturday 10/24

$23

Sunday 10/25

$34

Monday 10/26

$39

Tuesday 10/27

$59

Wednesday 10/28

$67

Thursday 10/29

$73

Friday 10/30

$90

Saturday 10/31

$93

Sunday 11/01

$103

Monday 11/02

$47

Tuesday 11/03

$41

Wednesday 11/04

$29

Thursday 11/05

$28

Friday 11/06

$31

Saturday 11/07

$40

Sunday 11/08

$48

Monday 11/09

$32

Tuesday 11/10

$46

Wednesday 11/11

$43

Thursday 11/12

$40

Friday 11/13

$40

Saturday 11/14

The cheapest time to travel from Florence to Lyon

See here on which day and which time of the day you can find the cheapest bus ticket from Florence to Lyon, for the next 30 days.

With a price starting from $22, Thursday is the cheapest day for a bus from Florence to Lyon. Tuesday instead is the most expensive day with prices starting from $41.

Morning is the cheapest day time for bus tickets from Florence to Lyon, with $22. Evening is the most expensive time of the day with prices starting from $55.

How to save money travelling from Florence to Lyon

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Florence to Lyon in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Florence to Lyon, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Florence to Lyon are also emptier.

All bus stations and stops in Florence and Lyon

In the map below, you can see where to find all bus stations in Florence and Lyon.

Guidoni T2 Bus Station

Viale Alessandro Guidoni 211

Piazza della Stazione Bus Station

Piazza della Stazione

Piazzale Montelungo Bus Stop

Viale Filippo Strozzi - Piazzale Montelungo (Stazione Novella)

Villa Costanza Bus Station

A1 73B

Calenzano Testanera Bus Stop

Via Vittorio Emanuele 3

Perrache Bus Stop

Cours de Verdun 14

Lyon Avenue Tony Garnier Bus Stop

Avenue Tony Garnier 52

Saint Paul Train Station

Pont Kitchener R.G. Bus Stop

Cours de Verdun

Maison Carrée Bus Stop

Les Charrières 69570

Service and Comfort on the bus from Florence to Lyon

Want to know which seat classes are available on the buses from Florence to Lyon? Or which bus companies serve the route Florence to Lyon? Below you will find answers to your questions.

FAQs about the Florence to Lyon bus

How much does a Florence Lyon bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $22 and takes 11h 10m to reach Lyon. Compare offers to save money!

How much could I save by comparing buses from Florence to Lyon?

This route is offered by 3 companies with a range of ticket prices between $22 and $172. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Lyon.

On average, how many connections are available from Florence to Lyon each day?

Every day, the Florence to Lyon bus route is served by approximately 19 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Florence to Lyon take?

The fastest bus from Florence to Lyon is offered by FlixBus and takes 10h 40m. Bus tickets for this connection cost $65. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Florence to Lyon?

The earliest bus arriving in Lyon from Florence starts at 11:55 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Florence to Lyon?

The latest bus trip departing from Florence for Lyon starts at 11:40 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Florence Lyon route?

When traveling by bus from Florence to Lyon, passengers can travel with FlixBus, Itabus and BlaBlaCar Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Florence and Lyon?

You can check all the direct connections between Florence and Lyon by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Itabus and BlaBlaCar Bus.

What can I take with me on the Florence to Lyon bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Florence Lyon bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Florence Lyon bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Florence to Lyon on your planned travel date.

How does CheckMyBus find the best bus deals from Florence to Lyon?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 19 daily trips between Florence and Lyon. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Florence to Lyon?

Prices and availability for 19 trips between Florence and Lyon change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Florence to Lyon

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Florence and to Lyon

Here’s an overview of the most popular bus routes to Florence and to Lyon. Simply click on the connection of your choice, and you will find all the details about your bus route!