Compare all timetables for the bus from Florence, SC to Jacksonville, FL
Here is a selection of the cheapest bus trips from the schedule from Florence, SC to Jacksonville, FL from various bus operators like Greyhound US for the next days.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 18h 55m | 12:05 PM | Florence, SC | Bus Station | 7:00 AM | Jacksonville, FL | Downtown Bus Stop | Economy | $75 |
A Bus from Greyhound US goes from Bus Station, Florence, SC (USA) at 10/21/2026 12:05:00 PM to Downtown Bus Stop, Jacksonville, FL (USA) arriving at 10/22/2026 7:00:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 18h 55m
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| Greyhound US | 16h 5m | 2:55 PM | Florence, SC | Bus Station | 7:00 AM | Jacksonville, FL | Downtown Bus Stop | Economy | $75 |
A Bus from Greyhound US goes from Bus Station, Florence, SC (USA) at 10/21/2026 2:55:00 PM to Downtown Bus Stop, Jacksonville, FL (USA) arriving at 10/22/2026 7:00:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 16h 5m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 18h 55m | 12:05 PM | Florence, SC | Bus Station | 7:00 AM | Jacksonville, FL | Downtown Bus Stop | Economy | $84 |
A Bus from Greyhound US goes from Bus Station, Florence, SC (USA) at 10/25/2026 12:05:00 PM to Downtown Bus Stop, Jacksonville, FL (USA) arriving at 10/26/2026 7:00:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 18h 55m
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| Greyhound US | 16h 5m | 2:55 PM | Florence, SC | Bus Station | 7:00 AM | Jacksonville, FL | Downtown Bus Stop | Economy | $84 |
A Bus from Greyhound US goes from Bus Station, Florence, SC (USA) at 10/25/2026 2:55:00 PM to Downtown Bus Stop, Jacksonville, FL (USA) arriving at 10/26/2026 7:00:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 16h 5m
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Did you know that if you travel from Florence, SC to Jacksonville, FL via Atlanta, GA, you can save more than $12? You can find the corresponding connections below.
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Greyhound US16h 5m02:55 PMFlorence, SCBus Station9:35 PMAtlanta, GAGarnett Transit Station0EconomyA Bus from Greyhound US goes from Bus Station, Florence, SC (USA) at 10/27/2026 2:55:00 PM to Garnett Transit Station, Atlanta, GA (USA) arriving at 10/27/2026 9:35:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 6h 40m
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FlixBus6h 35m012:25 AMAtlanta, GAGarnett Transit Station7:00 AMJacksonville, FLDowntown Bus Stop0EconomyA Bus from FlixBus goes from Garnett Transit Station, Atlanta, GA (USA) at 10/28/2026 12:25:00 AM to Downtown Bus Stop, Jacksonville, FL (USA) arriving at 10/28/2026 7:00:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 6h 35m
Waiting Time 2h 50mTravel time is the same as the direct connection, but you will save $12 -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 18h 55m | 12:05 PM | Florence, SC | Bus Station | 7:00 AM | Jacksonville, FL | Downtown Bus Stop | Economy | $79 |
A Bus from Greyhound US goes from Bus Station, Florence, SC (USA) at 10/26/2026 12:05:00 PM to Downtown Bus Stop, Jacksonville, FL (USA) arriving at 10/27/2026 7:00:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 18h 55m
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| Greyhound US | 16h 5m | 2:55 PM | Florence, SC | Bus Station | 7:00 AM | Jacksonville, FL | Downtown Bus Stop | Economy | $80 |
A Bus from Greyhound US goes from Bus Station, Florence, SC (USA) at 10/26/2026 2:55:00 PM to Downtown Bus Stop, Jacksonville, FL (USA) arriving at 10/27/2026 7:00:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 16h 5m
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Best Price Offer: The price for the cheapest bus from Florence, SC to Jacksonville, FL is $39 on 10/26/2026. Flexible travelers save on ticket prices.
Facts about the bus from Florence, SC to Jacksonville, FL
Compare all providers like Greyhound US that travel 2 times every day by bus from Florence, SC to Jacksonville, FL in one click! Book your bus ticket from Florence, SC to Jacksonville, FL starting from $39!
| Cheapest Bus | $39 |
| Fastest Bus | 16h 5m |
| Earliest Bus | 12:05 PM |
| Latest Bus | 2:55 PM |
| Daily Bus Routes | 2 Ø |
| Distance | 289.6 miles |
| Bus Companies | Greyhound US |
Cheapest bus connections from Florence, SC to Jacksonville, FL
Every day, 2 buses from 1 bus companies leave Florence, SC for Jacksonville, FL: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/21/2026 and for the following days.
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
10/18
Monday
10/19
Tuesday
10/20
Wednesday
10/21
$75
Thursday
10/22
Friday
10/23
Saturday
10/24
Sunday
10/25
$54
Monday
10/26
$39
Tuesday
10/27
Wednesday
10/28
Thursday
10/29
Friday
10/30
$45
Saturday
10/31
$47
Sunday
11/01
Monday
11/02
$44
Tuesday
11/03
Wednesday
11/04
Thursday
11/05
Friday
11/06
Saturday
11/07
$44
Sunday
11/08
Monday
11/09
$47
Tuesday
11/10
Wednesday
11/11
Thursday
11/12
Friday
11/13
Saturday
11/14
How to save money travelling from Florence, SC to Jacksonville, FL
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:
Book the ticket from Florence, SC to Jacksonville, FL in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Florence, SC to Jacksonville, FL, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Florence, SC to Jacksonville, FL are also emptier.All bus stations and stops in Florence, SC and Jacksonville, FL
In the map below, you can see where to find all bus stations in Florence, SC and Jacksonville, FL.
Service and Comfort on the bus from Florence, SC to Jacksonville, FL
Want to know which seat classes are available on the buses from Florence, SC to Jacksonville, FL? Or which bus companies serve the route Florence, SC to Jacksonville, FL? Below you will find answers to your questions.
FAQs about the Florence, SC to Jacksonville, FL bus
How much does a Florence, SC Jacksonville, FL bus trip cost?
This depends on, among other things, the day and time of travel. The cheapest trip is available from $39 and takes 18h 55m to reach Jacksonville, FL. Compare offers to save money!
How much could I save by comparing buses from Florence, SC to Jacksonville, FL?
This route is offered by 1 companies with a range of ticket prices between $39 and $84. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Jacksonville, FL.
On average, how many connections are available from Florence, SC to Jacksonville, FL each day?
Every day, the Florence, SC to Jacksonville, FL bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.
How long does a bus journey from Florence, SC to Jacksonville, FL take?
The fastest bus from Florence, SC to Jacksonville, FL is offered by Greyhound US and takes 16h 5m. Bus tickets for this connection cost $75. In this context, bear in mind that the journey can take longer due to traffic.
What time is the first bus from Florence, SC to Jacksonville, FL?
The earliest bus arriving in Jacksonville, FL from Florence, SC starts at 12:05 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.
What time is the last bus from Florence, SC to Jacksonville, FL?
The latest bus trip departing from Florence, SC for Jacksonville, FL starts at 2:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.
Which bus companies operate the Florence, SC Jacksonville, FL route?
When traveling by bus from Florence, SC to Jacksonville, FL, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.
Is there a direct bus between Florence, SC and Jacksonville, FL?
You can check all the direct connections between Florence, SC and Jacksonville, FL by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.
What can I take with me on the Florence, SC to Jacksonville, FL bus route?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Florence, SC Jacksonville, FL bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.
What equipment is available for the Florence, SC Jacksonville, FL bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Florence, SC to Jacksonville, FL on your planned travel date.
How does CheckMyBus find the best bus deals from Florence, SC to Jacksonville, FL?
CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Florence, SC and Jacksonville, FL. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.
How does CheckMyBus technology work for trips from Florence, SC to Jacksonville, FL?
Prices and availability for 2 trips between Florence, SC and Jacksonville, FL change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.
Available seat classes which are offered on the bus route Florence, SC to Jacksonville, FL
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Florence, SC and to Jacksonville, FL
Here’s an overview of the most popular bus routes to Florence, SC and to Jacksonville, FL. Simply click on the connection of your choice, and you will find all the details about your bus route!
- Bus Routes to Florence, SC
- From Asheville, NC to Florence, SC bus
- Buses to Florence, SC from Atlanta, GA
- Bus Bakersfield, CA - Florence, SC
- Buses from Cambridge, MA to Florence, SC
- Bus Camden, NJ to Florence, SC
- Bus Charleston, SC - Florence, SC
- Buses to Florence, SC from Charlotte
- Bus Chicago to Florence, SC
- Bus to Florence, SC from College Park, MD
- Bus to Florence, SC from Fredericksburg, VA
- Bus Madison, WI to Florence, SC
- Bus to Florence, SC from Miami
- Myrtle Beach, SC to Florence, SC bus
- Bus from New York to Florence, SC
- From Oklahoma City, OK to Florence, SC bus
- Bus Raleigh, NC to Florence, SC
- Bus Shreveport, LA to Florence, SC
- Bus Syracuse, NY to Florence, SC
- Bus Tallahassee, FL - Florence, SC
- Bus Worcester, MA to Florence, SC
- Bus Routes to Jacksonville, FL
- Columbus, OH to Jacksonville, FL bus
- Bus to Jacksonville, FL from Fort Lauderdale, FL
- Fort Myers, FL to Jacksonville, FL bus
- Bus from Gainesville, FL to Jacksonville, FL
- Bus Knoxville, TN to Jacksonville, FL
- Buses from Mobile, AL to Jacksonville, FL
- Bus to Jacksonville, FL from Montgomery, AL
- Bus New York - Jacksonville, FL
- Buses Newark to Jacksonville, FL
- Bus from Ocala, FL to Jacksonville, FL
- From Panama City Beach, FL to Jacksonville, FL bus
- Buses Petersburg, VA - Jacksonville, FL
- Buses to Jacksonville, FL from Port Saint Lucie, FL
- Buses Raleigh, NC - Jacksonville, FL
- Richmond, VA to Jacksonville, FL bus
- Bus Savannah, GA to Jacksonville, FL
- Buses Tampa - Jacksonville, FL
- From Valdosta, GA to Jacksonville, FL bus
- Buses Washington, DC - Jacksonville, FL
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Popular Airport Shuttles to Florence, SC and to Jacksonville, FL
