Bus Clarksville, TN to Greenville, SC

Compare all timetables for the bus from Clarksville, TN to Greenville, SC

Here is a selection of the cheapest bus trips from the schedule from Clarksville, TN to Greenville, SC from various bus operators like Greyhound US or FlixBus for the next days.

today

tomorrow

$60

Saturday

$65

Sunday

$62

Monday

$55

Tuesday

$57

Wednesday

$50

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	10h 25m	1:10 AM	Clarksville, TN	Park & Ride	12:35 PM	Greenville, SC	Woodruff Rd	Economy	$60	A Bus from Greyhound US goes from Park & Ride, Clarksville, TN (USA) at 8/28/2026 1:10:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 8/28/2026 12:35:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 10h 25m
Greyhound US	11h 25m	2:50 PM	Clarksville, TN	Park & Ride	3:15 AM	Greenville, SC	Woodruff Rd	Economy	$60	A Bus from Greyhound US goes from Park & Ride, Clarksville, TN (USA) at 8/28/2026 2:50:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 8/29/2026 3:15:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 11h 25m
Greyhound US	9h 55m	8:05 PM	Clarksville, TN	Park & Ride	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$60	A Bus from Greyhound US goes from Park & Ride, Clarksville, TN (USA) at 8/28/2026 8:05:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 8/29/2026 7:00:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 9h 55m
FlixBus	10h 30m	4:40 AM	Clarksville, TN	Park & Ride	4:10 PM	Greenville, SC	Woodruff Rd	Economy	$60	A Bus from FlixBus goes from Park & Ride, Clarksville, TN (USA) at 8/28/2026 4:40:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 8/28/2026 4:10:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 10h 30m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	10h 25m	1:10 AM	Clarksville, TN	Park & Ride	12:35 PM	Greenville, SC	Woodruff Rd	Economy	$65	A Bus from Greyhound US goes from Park & Ride, Clarksville, TN (USA) at 8/29/2026 1:10:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 8/29/2026 12:35:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 10h 25m
Greyhound US	9h 55m	8:05 PM	Clarksville, TN	Park & Ride	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$65	A Bus from Greyhound US goes from Park & Ride, Clarksville, TN (USA) at 8/29/2026 8:05:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 8/30/2026 7:00:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 9h 55m
FlixBus	10h 30m	4:40 AM	Clarksville, TN	Park & Ride	4:10 PM	Greenville, SC	Woodruff Rd	Economy	$65	A Bus from FlixBus goes from Park & Ride, Clarksville, TN (USA) at 8/29/2026 4:40:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 8/29/2026 4:10:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 10h 30m
Greyhound US	11h 25m	2:50 PM	Clarksville, TN	Park & Ride	3:15 AM	Greenville, SC	Woodruff Rd	Economy	$76	A Bus from Greyhound US goes from Park & Ride, Clarksville, TN (USA) at 8/29/2026 2:50:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 8/30/2026 3:15:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 11h 25m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	10h 30m	4:40 AM	Clarksville, TN	Park & Ride	4:10 PM	Greenville, SC	Woodruff Rd	Economy	$62	A Bus from FlixBus goes from Park & Ride, Clarksville, TN (USA) at 8/30/2026 4:40:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 8/30/2026 4:10:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 10h 30m
Greyhound US	10h 25m	1:10 AM	Clarksville, TN	Park & Ride	12:35 PM	Greenville, SC	Woodruff Rd	Economy	$63	A Bus from Greyhound US goes from Park & Ride, Clarksville, TN (USA) at 8/30/2026 1:10:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 8/30/2026 12:35:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 10h 25m
Greyhound US	9h 55m	8:05 PM	Clarksville, TN	Park & Ride	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$63	A Bus from Greyhound US goes from Park & Ride, Clarksville, TN (USA) at 8/30/2026 8:05:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 8/31/2026 7:00:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 9h 55m
Greyhound US	11h 25m	2:50 PM	Clarksville, TN	Park & Ride	3:15 AM	Greenville, SC	Woodruff Rd	Economy	$65	A Bus from Greyhound US goes from Park & Ride, Clarksville, TN (USA) at 8/30/2026 2:50:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 8/31/2026 3:15:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 11h 25m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	10h 25m	1:10 AM	Clarksville, TN	Park & Ride	12:35 PM	Greenville, SC	Woodruff Rd	Economy	$55	A Bus from Greyhound US goes from Park & Ride, Clarksville, TN (USA) at 8/31/2026 1:10:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 8/31/2026 12:35:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 10h 25m
Greyhound US	9h 55m	8:05 PM	Clarksville, TN	Park & Ride	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$55	A Bus from Greyhound US goes from Park & Ride, Clarksville, TN (USA) at 8/31/2026 8:05:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 9/1/2026 7:00:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 9h 55m
FlixBus	10h 30m	4:40 AM	Clarksville, TN	Park & Ride	4:10 PM	Greenville, SC	Woodruff Rd	Economy	$55	A Bus from FlixBus goes from Park & Ride, Clarksville, TN (USA) at 8/31/2026 4:40:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 8/31/2026 4:10:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 10h 30m
Greyhound US	11h 25m	2:50 PM	Clarksville, TN	Park & Ride	3:15 AM	Greenville, SC	Woodruff Rd	Economy	$62	A Bus from Greyhound US goes from Park & Ride, Clarksville, TN (USA) at 8/31/2026 2:50:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 9/1/2026 3:15:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 11h 25m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	10h 30m	4:40 AM	Clarksville, TN	Park & Ride	4:10 PM	Greenville, SC	Woodruff Rd	Economy	$57	A Bus from FlixBus goes from Park & Ride, Clarksville, TN (USA) at 9/1/2026 4:40:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 9/1/2026 4:10:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 10h 30m
Greyhound US	11h 25m	2:50 PM	Clarksville, TN	Park & Ride	3:15 AM	Greenville, SC	Woodruff Rd	Economy	$57	A Bus from Greyhound US goes from Park & Ride, Clarksville, TN (USA) at 9/1/2026 2:50:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 9/2/2026 3:15:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 11h 25m
Greyhound US	9h 55m	8:05 PM	Clarksville, TN	Park & Ride	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$71	A Bus from Greyhound US goes from Park & Ride, Clarksville, TN (USA) at 9/1/2026 8:05:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 9/2/2026 7:00:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 9h 55m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	10h 30m	4:40 AM	Clarksville, TN	Park & Ride	4:10 PM	Greenville, SC	Woodruff Rd	Economy	$50	A Bus from FlixBus goes from Park & Ride, Clarksville, TN (USA) at 9/2/2026 4:40:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 9/2/2026 4:10:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 10h 30m
Greyhound US	11h 25m	2:50 PM	Clarksville, TN	Park & Ride	3:15 AM	Greenville, SC	Woodruff Rd	Economy	$51	A Bus from Greyhound US goes from Park & Ride, Clarksville, TN (USA) at 9/2/2026 2:50:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 9/3/2026 3:15:00 AM. 50 Economy ticket for $51 per person are available. Travel duration is 11h 25m
Greyhound US	9h 55m	8:05 PM	Clarksville, TN	Park & Ride	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$51	A Bus from Greyhound US goes from Park & Ride, Clarksville, TN (USA) at 9/2/2026 8:05:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 9/3/2026 7:00:00 AM. 50 Economy ticket for $51 per person are available. Travel duration is 9h 55m

Best Price Offer: The price for the cheapest bus from Clarksville, TN to Greenville, SC is $48 on 9/18/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Clarksville, TN and Greenville, SC

See here how frequent the connections between Clarksville, TN and Greenville, SC are, during different times and days of the week.

Friday is the busiest day, with more than 8 daily buses from Clarksville, TN to Greenville, SC. Tuesday has instead the fewest connections, with only 3 daily coaches between Clarksville, TN and Greenville, SC.

The busiest time of the day is the Night, with 12 buses from Clarksville, TN to Greenville, SC, while Afternoon sees the fewest connections between Clarksville, TN and Greenville, SC, with 7 offers.

Facts about the bus from Clarksville, TN to Greenville, SC

Compare all providers like Greyhound US and FlixBus that travel 4 times every day by bus from Clarksville, TN to Greenville, SC in one click! Book your bus ticket from Clarksville, TN to Greenville, SC starting from $48!

Cheapest Bus	$48
Fastest Bus	10h 55m
Earliest Bus	1:10 AM
Latest Bus	8:05 PM
Daily Bus Routes	4 Ø
Distance	294.3 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Clarksville, TN to Greenville, SC

Every day, 4 buses from 2 bus companies leave Clarksville, TN for Greenville, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 08/27/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 08/23

Monday 08/24

Tuesday 08/25

Wednesday 08/26

Thursday 08/27

$81

Friday 08/28

$60

Saturday 08/29

$65

Sunday 08/30

$62

Monday 08/31

$55

Tuesday 09/01

$57

Wednesday 09/02

$50

Thursday 09/03

Friday 09/04

Saturday 09/05

$82

Sunday 09/06

$72

Monday 09/07

Tuesday 09/08

$67

Wednesday 09/09

$63

Thursday 09/10

$70

Friday 09/11

Saturday 09/12

Sunday 09/13

$71

Monday 09/14

$65

Tuesday 09/15

Wednesday 09/16

Thursday 09/17

Friday 09/18

$48

Saturday 09/19

The cheapest time to travel from Clarksville, TN to Greenville, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Clarksville, TN to Greenville, SC, for the next 30 days.

With a price starting from $48, Friday is the cheapest day for a bus from Clarksville, TN to Greenville, SC. Tuesday instead is the most expensive day with prices starting from $57.

Night is the cheapest day time for bus tickets from Clarksville, TN to Greenville, SC, with $48. Afternoon is the most expensive time of the day with prices starting from $51.

How to save money travelling from Clarksville, TN to Greenville, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Clarksville, TN to Greenville, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Clarksville, TN to Greenville, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Clarksville, TN to Greenville, SC are also emptier.

Beloved bus companies from Clarksville, TN to Greenville, SC

These are the most booked bus companies between Clarksville, TN to Greenville, SC from our users.

Greyhound US from Clarksville, TN to Greenville, SC

Here you will find the key facts about the Greyhound US bus route Clarksville, TN to Greenville, SC:

Cheapest Price	$51
Fastest Bus	10h 55m
Earliest Bus	1:10 AM
Last Bus	8:05 PM
Daily Connections	3 Ø
Found on	8/2/2026

All bus stations and stops in Clarksville, TN and Greenville, SC

In the map below, you can see where to find all bus stations in Clarksville, TN and Greenville, SC.

Park & Ride

Bus Stop

Jefferson St 11

N Church St

Woodruff Rd

Woodruff Rd 1116

Greyhound Bus Station

Hendrix Dr 9

Guadalajara Supermarket

White Horse Rd 2803

McDonald's

Woodruff Rd 1111

Service and Comfort on the bus from Clarksville, TN to Greenville, SC

Want to know which seat classes are available on the buses from Clarksville, TN to Greenville, SC? Or which bus companies serve the route Clarksville, TN to Greenville, SC? Below you will find answers to your questions.

FAQs about the Clarksville, TN to Greenville, SC bus

How much does a Clarksville, TN Greenville, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $48 and takes 11h 30m to reach Greenville, SC. Compare offers to save money!

How much could I save by comparing buses from Clarksville, TN to Greenville, SC?

This route is offered by 2 companies with a range of ticket prices between $48 and $76. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Greenville, SC.

On average, how many connections are available from Clarksville, TN to Greenville, SC each day?

Every day, the Clarksville, TN to Greenville, SC bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Clarksville, TN to Greenville, SC take?

The fastest bus from Clarksville, TN to Greenville, SC is offered by Greyhound US and takes 10h 55m. Bus tickets for this connection cost $64. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Clarksville, TN to Greenville, SC?

The earliest bus arriving in Greenville, SC from Clarksville, TN starts at 1:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Clarksville, TN to Greenville, SC?

The latest bus trip departing from Clarksville, TN for Greenville, SC starts at 8:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Clarksville, TN Greenville, SC route?

When traveling by bus from Clarksville, TN to Greenville, SC, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Clarksville, TN and Greenville, SC?

You can check all the direct connections between Clarksville, TN and Greenville, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Clarksville, TN to Greenville, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Clarksville, TN Greenville, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Clarksville, TN Greenville, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Clarksville, TN to Greenville, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Clarksville, TN to Greenville, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 4 daily trips between Clarksville, TN and Greenville, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Clarksville, TN to Greenville, SC?

Prices and availability for 4 trips between Clarksville, TN and Greenville, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Clarksville, TN to Greenville, SC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Clarksville, TN and to Greenville, SC

Here’s an overview of the most popular bus routes to Clarksville, TN and to Greenville, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!