Bus Chicago to Mesa, AZ - Compare all Companies

Compare all timetables for the bus from Chicago to Mesa, AZ

Here is a selection of the cheapest bus trips from the schedule from Chicago to Mesa, AZ from various bus operators like Greyhound US or FlixBus for the next days.

today

$167

tomorrow

$166

Thursday

Friday

Saturday

$169

Sunday

$159

Monday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	45h 0m	11:10 PM	Chicago	Canal & Van Buren	6:10 PM	Mesa, AZ	Greyhound	Economy	$167	A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 10/20/2026 11:10:00 PM to Greyhound, Mesa, AZ (USA) arriving at 10/22/2026 6:10:00 PM. 50 Economy ticket for $167 per person are available. Travel duration is 45h 0m
Greyhound US	45h 20m	10:50 PM	Chicago	Downtown Bus Station	6:10 PM	Mesa, AZ	Greyhound	Economy	$167	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 10/20/2026 10:50:00 PM to Greyhound, Mesa, AZ (USA) arriving at 10/22/2026 6:10:00 PM. 50 Economy ticket for $167 per person are available. Travel duration is 45h 20m
Greyhound US	42h 55m	2:45 PM	Chicago	Downtown Bus Station	7:40 AM	Mesa, AZ	Greyhound	Economy	$172	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 10/20/2026 2:45:00 PM to Greyhound, Mesa, AZ (USA) arriving at 10/22/2026 7:40:00 AM. 50 Economy ticket for $172 per person are available. Travel duration is 42h 55m
Greyhound US	47h 25m	10:15 AM	Chicago	Canal & Van Buren	7:40 AM	Mesa, AZ	Greyhound	Economy	$186	A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 10/20/2026 10:15:00 AM to Greyhound, Mesa, AZ (USA) arriving at 10/22/2026 7:40:00 AM. 50 Economy ticket for $186 per person are available. Travel duration is 47h 25m
Greyhound US	44h 30m	11:40 PM	Chicago	95th Red Line Station	6:10 PM	Mesa, AZ	Greyhound	Economy	$218	A Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 10/20/2026 11:40:00 PM to Greyhound, Mesa, AZ (USA) arriving at 10/22/2026 6:10:00 PM. 50 Economy ticket for $218 per person are available. Travel duration is 44h 30m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	45h 0m	11:10 PM	Chicago	Canal & Van Buren	6:10 PM	Mesa, AZ	Greyhound	Economy	$166	A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 10/21/2026 11:10:00 PM to Greyhound, Mesa, AZ (USA) arriving at 10/23/2026 6:10:00 PM. 50 Economy ticket for $166 per person are available. Travel duration is 45h 0m
Greyhound US	45h 20m	10:50 PM	Chicago	Downtown Bus Station	6:10 PM	Mesa, AZ	Greyhound	Economy	$166	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 10/21/2026 10:50:00 PM to Greyhound, Mesa, AZ (USA) arriving at 10/23/2026 6:10:00 PM. 50 Economy ticket for $166 per person are available. Travel duration is 45h 20m
Greyhound US	47h 25m	10:15 AM	Chicago	Canal & Van Buren	7:40 AM	Mesa, AZ	Greyhound	Economy	$172	A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 10/21/2026 10:15:00 AM to Greyhound, Mesa, AZ (USA) arriving at 10/23/2026 7:40:00 AM. 50 Economy ticket for $172 per person are available. Travel duration is 47h 25m
Greyhound US	42h 55m	2:45 PM	Chicago	Downtown Bus Station	7:40 AM	Mesa, AZ	Greyhound	Economy	$172	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 10/21/2026 2:45:00 PM to Greyhound, Mesa, AZ (USA) arriving at 10/23/2026 7:40:00 AM. 50 Economy ticket for $172 per person are available. Travel duration is 42h 55m
Greyhound US	44h 30m	11:40 PM	Chicago	95th Red Line Station	6:10 PM	Mesa, AZ	Greyhound	Economy	$217	A Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 10/21/2026 11:40:00 PM to Greyhound, Mesa, AZ (USA) arriving at 10/23/2026 6:10:00 PM. 50 Economy ticket for $217 per person are available. Travel duration is 44h 30m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	43h 55m	12:15 AM	Chicago	Downtown Bus Station	6:10 PM	Mesa, AZ	Greyhound	Economy	$169	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 10/24/2026 12:15:00 AM to Greyhound, Mesa, AZ (USA) arriving at 10/25/2026 6:10:00 PM. 50 Economy ticket for $169 per person are available. Travel duration is 43h 55m
Greyhound US	45h 20m	10:50 PM	Chicago	Downtown Bus Station	6:10 PM	Mesa, AZ	Greyhound	Economy	$176	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 10/24/2026 10:50:00 PM to Greyhound, Mesa, AZ (USA) arriving at 10/26/2026 6:10:00 PM. 50 Economy ticket for $176 per person are available. Travel duration is 45h 20m
Greyhound US	45h 0m	11:10 PM	Chicago	Union Station	6:10 PM	Mesa, AZ	Greyhound	Economy	$176	A Bus from Greyhound US goes from Union Station, Chicago (USA) at 10/24/2026 11:10:00 PM to Greyhound, Mesa, AZ (USA) arriving at 10/26/2026 6:10:00 PM. 50 Economy ticket for $176 per person are available. Travel duration is 45h 0m
FlixBus	40h 35m	5:05 PM	Chicago	Downtown Bus Station	7:40 AM	Mesa, AZ	Greyhound	Economy	$187	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 10/24/2026 5:05:00 PM to Greyhound, Mesa, AZ (USA) arriving at 10/26/2026 7:40:00 AM. 50 Economy ticket for $187 per person are available. Travel duration is 40h 35m
Greyhound US	47h 25m	10:15 AM	Chicago	Union Station	7:40 AM	Mesa, AZ	Greyhound	Economy	$189	A Bus from Greyhound US goes from Union Station, Chicago (USA) at 10/24/2026 10:15:00 AM to Greyhound, Mesa, AZ (USA) arriving at 10/26/2026 7:40:00 AM. 50 Economy ticket for $189 per person are available. Travel duration is 47h 25m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	43h 55m	12:15 AM	Chicago	Downtown Bus Station	6:10 PM	Mesa, AZ	Greyhound	Economy	$159	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 10/25/2026 12:15:00 AM to Greyhound, Mesa, AZ (USA) arriving at 10/26/2026 6:10:00 PM. 50 Economy ticket for $159 per person are available. Travel duration is 43h 55m
Greyhound US	47h 25m	10:15 AM	Chicago	Canal & Van Buren	7:40 AM	Mesa, AZ	Greyhound	Economy	$166	A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 10/25/2026 10:15:00 AM to Greyhound, Mesa, AZ (USA) arriving at 10/27/2026 7:40:00 AM. 50 Economy ticket for $166 per person are available. Travel duration is 47h 25m
FlixBus	40h 35m	5:05 PM	Chicago	Downtown Bus Station	7:40 AM	Mesa, AZ	Greyhound	Economy	$170	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 10/25/2026 5:05:00 PM to Greyhound, Mesa, AZ (USA) arriving at 10/27/2026 7:40:00 AM. 50 Economy ticket for $170 per person are available. Travel duration is 40h 35m
Greyhound US	45h 20m	10:50 PM	Chicago	Downtown Bus Station	6:10 PM	Mesa, AZ	Greyhound	Economy	$174	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 10/25/2026 10:50:00 PM to Greyhound, Mesa, AZ (USA) arriving at 10/27/2026 6:10:00 PM. 50 Economy ticket for $174 per person are available. Travel duration is 45h 20m
Greyhound US	45h 0m	11:10 PM	Chicago	Canal & Van Buren	6:10 PM	Mesa, AZ	Greyhound	Economy	$174	A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 10/25/2026 11:10:00 PM to Greyhound, Mesa, AZ (USA) arriving at 10/27/2026 6:10:00 PM. 50 Economy ticket for $174 per person are available. Travel duration is 45h 0m

Best Price Offer: The price for the cheapest bus from Chicago to Mesa, AZ is $150 on 10/19/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Chicago and Mesa, AZ

See here how frequent the connections between Chicago and Mesa, AZ are, during different times and days of the week.

Wednesday is the busiest day, with more than 10 daily buses from Chicago to Mesa, AZ. Saturday has instead the fewest connections, with only 5 daily coaches between Chicago and Mesa, AZ.

The busiest time of the day is the Evening, with 13 buses from Chicago to Mesa, AZ, while Night sees the fewest connections between Chicago and Mesa, AZ, with 3 offers.

Facts about the bus from Chicago to Mesa, AZ

Compare all providers like Greyhound US and FlixBus that travel 7 times every day by bus from Chicago to Mesa, AZ in one click! Book your bus ticket from Chicago to Mesa, AZ starting from $150!

Cheapest Bus	$150
Fastest Bus	38h 35m
Earliest Bus	10:15 AM
Latest Bus	11:40 PM
Daily Bus Routes	7 Ø
Distance	1,440.9 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Chicago to Mesa, AZ

Every day, 7 buses from 2 bus companies leave Chicago for Mesa, AZ: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/20/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 10/18

Monday 10/19

Tuesday 10/20

$167

Wednesday 10/21

$171

Thursday 10/22

Friday 10/23

Saturday 10/24

$169

Sunday 10/25

$159

Monday 10/26

Tuesday 10/27

$162

Wednesday 10/28

$178

Thursday 10/29

$176

Friday 10/30

Saturday 10/31

Sunday 11/01

Monday 11/02

$159

Tuesday 11/03

$174

Wednesday 11/04

$168

Thursday 11/05

$155

Friday 11/06

$155

Saturday 11/07

Sunday 11/08

Monday 11/09

$166

Tuesday 11/10

$161

Wednesday 11/11

Thursday 11/12

Friday 11/13

Saturday 11/14

The cheapest time to travel from Chicago to Mesa, AZ

See here on which day and which time of the day you can find the cheapest bus ticket from Chicago to Mesa, AZ, for the next 30 days.

With a price starting from $159, Sunday is the cheapest day for a bus from Chicago to Mesa, AZ. Saturday instead is the most expensive day with prices starting from $169.

Night is the cheapest day time for bus tickets from Chicago to Mesa, AZ, with $155. Afternoon is the most expensive time of the day with prices starting from $170.

How to save money travelling from Chicago to Mesa, AZ

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Chicago to Mesa, AZ in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Chicago to Mesa, AZ, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Chicago to Mesa, AZ are also emptier.

All bus stations and stops in Chicago and Mesa, AZ

In the map below, you can see where to find all bus stations in Chicago and Mesa, AZ.

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

W Cermak Rd

W Cermak Rd 1001

Greyhound

S Country Club Dr 1423

Fry’s Fuel Center

W Main Street 1235

Service and Comfort on the bus from Chicago to Mesa, AZ

Want to know which seat classes are available on the buses from Chicago to Mesa, AZ? Or which bus companies serve the route Chicago to Mesa, AZ? Below you will find answers to your questions.

FAQs about the Chicago to Mesa, AZ bus

How much does a Chicago Mesa, AZ bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $150 and takes 41h 55m to reach Mesa, AZ. Compare offers to save money!

How much could I save by comparing buses from Chicago to Mesa, AZ?

This route is offered by 2 companies with a range of ticket prices between $150 and $233. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Mesa, AZ.

On average, how many connections are available from Chicago to Mesa, AZ each day?

Every day, the Chicago to Mesa, AZ bus route is served by approximately 7 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Chicago to Mesa, AZ take?

The fastest bus from Chicago to Mesa, AZ is offered by FlixBus and takes 38h 35m. Bus tickets for this connection cost $187. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Chicago to Mesa, AZ?

The earliest bus arriving in Mesa, AZ from Chicago starts at 10:15 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Chicago to Mesa, AZ?

The latest bus trip departing from Chicago for Mesa, AZ starts at 11:40 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Chicago Mesa, AZ route?

When traveling by bus from Chicago to Mesa, AZ, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Chicago and Mesa, AZ?

You can check all the direct connections between Chicago and Mesa, AZ by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Chicago to Mesa, AZ bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Chicago Mesa, AZ bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Chicago Mesa, AZ bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Chicago to Mesa, AZ on your planned travel date.

How does CheckMyBus find the best bus deals from Chicago to Mesa, AZ?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 7 daily trips between Chicago and Mesa, AZ. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Chicago to Mesa, AZ?

Prices and availability for 7 trips between Chicago and Mesa, AZ change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Chicago to Mesa, AZ

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Chicago and to Mesa, AZ

Here’s an overview of the most popular bus routes to Chicago and to Mesa, AZ. Simply click on the connection of your choice, and you will find all the details about your bus route!