Bus Chicago to Harrisburg, PA - Compare all Companies

Compare all timetables for the bus from Chicago to Harrisburg, PA

Here is a selection of the cheapest bus trips from the schedule from Chicago to Harrisburg, PA from various bus operators like Greyhound US or FlixBus for the next days.

today

$75

tomorrow

Saturday

Sunday

$86

Monday

Tuesday

$88

Wednesday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	16h 40m	5:05 PM	Chicago	95th Red Line Station	10:45 AM	Harrisburg, PA	Bus Station	Economy	$75	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 8/27/2026 5:05:00 PM to Bus Station, Harrisburg, PA (USA) arriving at 8/28/2026 10:45:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 16h 40m
FlixBus	29h 0m	11:55 PM	Chicago	95th Red Line Station	5:55 AM	Harrisburg, PA	Bus Station	Economy	$75	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 8/27/2026 11:55:00 PM to Bus Station, Harrisburg, PA (USA) arriving at 8/29/2026 5:55:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 29h 0m
FlixBus	15h 55m	7:15 PM	Chicago	Downtown Bus Station	12:10 PM	Harrisburg, PA	Bus Station	Economy	$77	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 8/27/2026 7:15:00 PM to Bus Station, Harrisburg, PA (USA) arriving at 8/28/2026 12:10:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 15h 55m
Greyhound US	22h 50m	11:45 PM	Chicago	95th Red Line Station	11:35 PM	Harrisburg, PA	Bus Station	Economy	$85	A Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 8/27/2026 11:45:00 PM to Bus Station, Harrisburg, PA (USA) arriving at 8/28/2026 11:35:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 22h 50m
Greyhound US	15h 45m	6:00 PM	Chicago	Downtown Bus Station	10:45 AM	Harrisburg, PA	Bus Station	Economy	$85	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 8/27/2026 6:00:00 PM to Bus Station, Harrisburg, PA (USA) arriving at 8/28/2026 10:45:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 15h 45m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	29h 0m	11:55 PM	Chicago	95th Red Line Station	5:55 AM	Harrisburg, PA	Bus Station	Economy	$86	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 8/30/2026 11:55:00 PM to Bus Station, Harrisburg, PA (USA) arriving at 9/1/2026 5:55:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 29h 0m
FlixBus	15h 55m	7:15 PM	Chicago	Downtown Bus Station	12:10 PM	Harrisburg, PA	Bus Station	Economy	$86	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 8/30/2026 7:15:00 PM to Bus Station, Harrisburg, PA (USA) arriving at 8/31/2026 12:10:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 15h 55m
FlixBus	16h 40m	5:05 PM	Chicago	95th Red Line Station	10:45 AM	Harrisburg, PA	Bus Station	Economy	$87	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 8/30/2026 5:05:00 PM to Bus Station, Harrisburg, PA (USA) arriving at 8/31/2026 10:45:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 16h 40m
Greyhound US	22h 50m	11:45 PM	Chicago	95th Red Line Station	11:35 PM	Harrisburg, PA	Bus Station	Economy	$95	A Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 8/30/2026 11:45:00 PM to Bus Station, Harrisburg, PA (USA) arriving at 8/31/2026 11:35:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 22h 50m
Greyhound US	15h 45m	6:00 PM	Chicago	Downtown Bus Station	10:45 AM	Harrisburg, PA	Bus Station	Economy	$102	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 8/30/2026 6:00:00 PM to Bus Station, Harrisburg, PA (USA) arriving at 8/31/2026 10:45:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 15h 45m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	17h 55m	7:00 AM	Chicago	Downtown Bus Station	1:55 AM	Harrisburg, PA	Bus Station	Economy	$88	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 9/1/2026 7:00:00 AM to Bus Station, Harrisburg, PA (USA) arriving at 9/2/2026 1:55:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 17h 55m
Greyhound US	16h 5m	6:30 AM	Chicago	Downtown Bus Station	11:35 PM	Harrisburg, PA	Bus Station	Economy	$93	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 9/1/2026 6:30:00 AM to Bus Station, Harrisburg, PA (USA) arriving at 9/1/2026 11:35:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 16h 5m
Greyhound US	23h 0m	11:35 PM	Chicago	Downtown Bus Station	11:35 PM	Harrisburg, PA	Bus Station	Economy	$98	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 9/1/2026 11:35:00 PM to Bus Station, Harrisburg, PA (USA) arriving at 9/2/2026 11:35:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 23h 0m
Greyhound US	19h 0m	9:55 AM	Chicago	Downtown Bus Station	5:55 AM	Harrisburg, PA	Bus Station	Economy	$99	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 9/1/2026 9:55:00 AM to Bus Station, Harrisburg, PA (USA) arriving at 9/2/2026 5:55:00 AM. 50 Economy ticket for $99 per person are available. Travel duration is 19h 0m

Best Price Offer: The price for the cheapest bus from Chicago to Harrisburg, PA is $72 on 9/15/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Chicago and Harrisburg, PA

See here how frequent the connections between Chicago and Harrisburg, PA are, during different times and days of the week.

Sunday is the busiest day, with more than 28 daily buses from Chicago to Harrisburg, PA. Tuesday has instead the fewest connections, with only 7 daily coaches between Chicago and Harrisburg, PA.

The busiest time of the day is the Evening, with 31 buses from Chicago to Harrisburg, PA, while Afternoon sees the fewest connections between Chicago and Harrisburg, PA, with 4 offers.

Facts about the bus from Chicago to Harrisburg, PA

Compare all providers like Greyhound US and FlixBus that travel 17 times every day by bus from Chicago to Harrisburg, PA in one click! Book your bus ticket from Chicago to Harrisburg, PA starting from $72!

Cheapest Bus	$72
Fastest Bus	16h 30m
Earliest Bus	10:15 AM
Latest Bus	11:35 PM
Daily Bus Routes	17 Ø
Distance	573.8 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Chicago to Harrisburg, PA

Every day, 17 buses from 2 bus companies leave Chicago for Harrisburg, PA: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 08/27/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 08/23

Monday 08/24

Tuesday 08/25

Wednesday 08/26

Thursday 08/27

$75

Friday 08/28

Saturday 08/29

Sunday 08/30

$86

Monday 08/31

Tuesday 09/01

$88

Wednesday 09/02

Thursday 09/03

$79

Friday 09/04

$97

Saturday 09/05

$78

Sunday 09/06

Monday 09/07

Tuesday 09/08

$86

Wednesday 09/09

Thursday 09/10

$81

Friday 09/11

$81

Saturday 09/12

$77

Sunday 09/13

$79

Monday 09/14

Tuesday 09/15

$72

Wednesday 09/16

Thursday 09/17

$76

Friday 09/18

$75

Saturday 09/19

The cheapest time to travel from Chicago to Harrisburg, PA

See here on which day and which time of the day you can find the cheapest bus ticket from Chicago to Harrisburg, PA, for the next 30 days.

With a price starting from $72, Tuesday is the cheapest day for a bus from Chicago to Harrisburg, PA. Sunday instead is the most expensive day with prices starting from $79.

Night is the cheapest day time for bus tickets from Chicago to Harrisburg, PA, with $72. Morning is the most expensive time of the day with prices starting from $88.

How to save money travelling from Chicago to Harrisburg, PA

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Chicago to Harrisburg, PA in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Chicago to Harrisburg, PA, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Chicago to Harrisburg, PA are also emptier.

Beloved bus companies from Chicago to Harrisburg, PA

These are the most booked bus companies between Chicago to Harrisburg, PA from our users.

Greyhound US from Chicago to Harrisburg, PA

Here you will find the key facts about the Greyhound US bus route Chicago to Harrisburg, PA:

Cheapest Price	$85
Fastest Bus	16h 45m
Earliest Bus	10:15 AM
Last Bus	11:35 PM
Daily Connections	10 Ø
Found on	8/8/2026

All bus stations and stops in Chicago and Harrisburg, PA

In the map below, you can see where to find all bus stations in Chicago and Harrisburg, PA.

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Bus Station

Market St 411

S 4th St & Chestnut St

Mall Parking Lot

Paxton St 3501

N Cameron St

N Cameron St 2000

Old Country Buffet

Jonestown Rd 5083

Service and Comfort on the bus from Chicago to Harrisburg, PA

Want to know which seat classes are available on the buses from Chicago to Harrisburg, PA? Or which bus companies serve the route Chicago to Harrisburg, PA? Below you will find answers to your questions.

FAQs about the Chicago to Harrisburg, PA bus

How much does a Chicago Harrisburg, PA bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $72 and takes 17h 40m to reach Harrisburg, PA. Compare offers to save money!

How much could I save by comparing buses from Chicago to Harrisburg, PA?

This route is offered by 2 companies with a range of ticket prices between $72 and $124. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Harrisburg, PA.

On average, how many connections are available from Chicago to Harrisburg, PA each day?

Every day, the Chicago to Harrisburg, PA bus route is served by approximately 17 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Chicago to Harrisburg, PA take?

The fastest bus from Chicago to Harrisburg, PA is offered by FlixBus and takes 16h 30m. Bus tickets for this connection cost $99. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Chicago to Harrisburg, PA?

The earliest bus arriving in Harrisburg, PA from Chicago starts at 10:15 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Chicago to Harrisburg, PA?

The latest bus trip departing from Chicago for Harrisburg, PA starts at 11:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Chicago Harrisburg, PA route?

When traveling by bus from Chicago to Harrisburg, PA, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Chicago and Harrisburg, PA?

You can check all the direct connections between Chicago and Harrisburg, PA by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Chicago to Harrisburg, PA bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Chicago Harrisburg, PA bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Chicago Harrisburg, PA bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Chicago to Harrisburg, PA on your planned travel date.

How does CheckMyBus find the best bus deals from Chicago to Harrisburg, PA?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 17 daily trips between Chicago and Harrisburg, PA. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Chicago to Harrisburg, PA?

Prices and availability for 17 trips between Chicago and Harrisburg, PA change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Chicago to Harrisburg, PA

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Chicago and to Harrisburg, PA

Here’s an overview of the most popular bus routes to Chicago and to Harrisburg, PA. Simply click on the connection of your choice, and you will find all the details about your bus route!