Bus Brussels Airport (BRU) to Prague: Find cheap tickets

Compare all timetables for the shuttles from Brussels Airport to Prague

Here is a selection of the cheapest shuttle trips from the schedule from Brussels Airport to Prague from various bus operators like FlixBus for the next days.

today

$98

tomorrow

$108

Saturday

$107

Sunday

$108

Monday

$75

Tuesday

$50

Wednesday

$49

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	17h 35m	1:40 PM	Brussels Airport	Brussels Airport	7:15 AM	Prague	ÚAN Florenc	Economy	$98	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/27/2026 1:40:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 8/28/2026 7:15:00 AM. 50 Economy ticket for $98 per person are available. Travel duration is 17h 35m
FlixBus	19h 15m	1:40 PM	Brussels Airport	Brussels Airport	8:55 AM	Prague	Na Knížecí Station	Economy	$98	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/27/2026 1:40:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 8/28/2026 8:55:00 AM. 50 Economy ticket for $98 per person are available. Travel duration is 19h 15m
FlixBus	23h 40m	1:40 PM	Brussels Airport	Brussels Airport	1:20 PM	Prague	Černý Most	Economy	$98	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/27/2026 1:40:00 PM to Černý Most, Prague (Czech Republic) arriving at 8/28/2026 1:20:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 23h 40m
FlixBus	21h 50m	1:40 PM	Brussels Airport	Brussels Airport	11:30 AM	Prague	Wilsonova Bus Station	Economy	$99	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/27/2026 1:40:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 8/28/2026 11:30:00 AM. 50 Economy ticket for $99 per person are available. Travel duration is 21h 50m
FlixBus	23h 30m	6:05 PM	Brussels Airport	Brussels Airport	5:35 PM	Prague	Hradčanská	Economy	$100	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/27/2026 6:05:00 PM to Hradčanská, Prague (Czech Republic) arriving at 8/28/2026 5:35:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 23h 30m

Did you know that if you travel from Brussels Airport to Prague via Brussels, you can save more than $25? You will find the corresponding connections below.
- FlixBus
  
  Save more than 26%
  
  14h 5m
  
  Brussels Airport
  
  7 mi
  
  10:25 AM
  
  Brussels
  North Station
  
  12:30 AM
  
  Prague
  Na Knížecí Station
  
  0 mi
  
  Economy
  
  $73
  
  A Bus from FlixBus goes from North Station, Brussels (Belgium) at 8/27/2026 10:25:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 8/28/2026 12:30:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 14h 5m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	17h 35m	1:40 PM	Brussels Airport	Brussels Airport	7:15 AM	Prague	ÚAN Florenc	Economy	$108	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/28/2026 1:40:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 8/29/2026 7:15:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 17h 35m
FlixBus	20h 15m	4:15 AM	Brussels Airport	Brussels Airport	12:30 AM	Prague	Na Knížecí Station	Economy	$121	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/28/2026 4:15:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 8/29/2026 12:30:00 AM. 50 Economy ticket for $121 per person are available. Travel duration is 20h 15m
FlixBus	20h 30m	4:15 AM	Brussels Airport	Brussels Airport	12:45 AM	Prague	Wilsonova Bus Station	Economy	$121	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/28/2026 4:15:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 8/29/2026 12:45:00 AM. 50 Economy ticket for $121 per person are available. Travel duration is 20h 30m
FlixBus	21h 40m	10:20 PM	Brussels Airport	Brussels Airport	8:00 PM	Prague	Hradčanská	Economy	$121	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/28/2026 10:20:00 PM to Hradčanská, Prague (Czech Republic) arriving at 8/29/2026 8:00:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 21h 40m
FlixBus	21h 25m	4:15 AM	Brussels Airport	Brussels Airport	1:40 AM	Prague	Wilsonova Bus Station	Economy	$122	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/28/2026 4:15:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 8/29/2026 1:40:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 21h 25m

Did you know that if you travel from Brussels Airport to Prague via Brussels, you can save more than $31? You will find the corresponding connections below.
- FlixBus
  
  Save more than 29%
  
  14h 5m
  
  Brussels Airport
  
  7 mi
  
  10:25 AM
  
  Brussels
  North Station
  
  12:30 AM
  
  Prague
  Na Knížecí Station
  
  0 mi
  
  Economy
  
  $77
  
  A Bus from FlixBus goes from North Station, Brussels (Belgium) at 8/28/2026 10:25:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 8/29/2026 12:30:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 14h 5m
Did you know that if you travel from Brussels Airport to Prague via Maastricht, you can save more than $26? You can find the corresponding connections below.
- FlixBus
  
  17h 5m
  
  0
  
  7:35 PM
  
  Brussels Airport
  Brussels Airport
  
  9:10 PM
  
  Maastricht
  Meerssenerweg
  
  0
  
  Economy
  
  $11
  
  A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/29/2026 7:35:00 PM to Meerssenerweg, Maastricht (Netherlands) arriving at 8/29/2026 9:10:00 PM. 50 Economy ticket for $11 per person are available. Travel duration is 1h 35m
- FlixBus
  
  13h 30m
  
  0
  
  11:10 PM
  
  Maastricht
  Meerssenerweg
  
  12:40 PM
  
  Prague
  ÚAN Florenc
  
  0
  
  Economy
  
  $70
  
  A Bus from FlixBus goes from Meerssenerweg, Maastricht (Netherlands) at 8/29/2026 11:10:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 8/30/2026 12:40:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 13h 30m
Travel Time is 0h 30m shorter, and you will save $26

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	17h 35m	1:40 PM	Brussels Airport	Brussels Airport	7:15 AM	Prague	ÚAN Florenc	Economy	$107	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/29/2026 1:40:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 8/30/2026 7:15:00 AM. 50 Economy ticket for $107 per person are available. Travel duration is 17h 35m
FlixBus	23h 40m	1:40 PM	Brussels Airport	Brussels Airport	1:20 PM	Prague	Černý Most	Economy	$111	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/29/2026 1:40:00 PM to Černý Most, Prague (Czech Republic) arriving at 8/30/2026 1:20:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 23h 40m
FlixBus	17h 5m	7:35 PM	Brussels Airport	Brussels Airport	12:40 PM	Prague	ÚAN Florenc	Economy	$112	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/29/2026 7:35:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 8/30/2026 12:40:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 17h 5m
FlixBus	21h 50m	1:40 PM	Brussels Airport	Brussels Airport	11:30 AM	Prague	Wilsonova Bus Station	Economy	$112	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/29/2026 1:40:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 8/30/2026 11:30:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 21h 50m
FlixBus	22h 20m	9:00 PM	Brussels Airport	Brussels Airport	7:20 PM	Prague	Wilsonova Bus Station	Economy	$112	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/29/2026 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 8/30/2026 7:20:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 22h 20m

Did you know that if you travel from Brussels Airport to Prague via Brussels, you can save more than $30? You will find the corresponding connections below.
- FlixBus
  
  Save more than 28%
  
  14h 5m
  
  Brussels Airport
  
  7 mi
  
  10:25 AM
  
  Brussels
  North Station
  
  12:30 AM
  
  Prague
  Na Knížecí Station
  
  0 mi
  
  Economy
  
  $77
  
  A Bus from FlixBus goes from North Station, Brussels (Belgium) at 8/29/2026 10:25:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 8/30/2026 12:30:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 14h 5m
Did you know that if you travel from Brussels Airport to Prague via Aachen, you can save more than $33? You can find the corresponding connections below.
- FlixBus
  
  17h 55m
  
  0
  
  7:35 PM
  
  Brussels Airport
  Brussels Airport
  
  10:40 PM
  
  Aachen
  West Train Station
  
  0
  
  Economy
  
  $26
  
  A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/30/2026 7:35:00 PM to West Train Station, Aachen (Germany) arriving at 8/30/2026 10:40:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 3h 5m
- FlixBus
  
  11h 40m
  
  0
  
  1:50 AM
  
  Aachen
  West Train Station
  
  1:30 PM
  
  Prague
  ÚAN Florenc
  
  0
  
  Economy
  
  $48
  
  A Bus from FlixBus goes from West Train Station, Aachen (Germany) at 8/31/2026 1:50:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 8/31/2026 1:30:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 11h 40m
Travel time is 0h 50m longer, but you will save $33

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	17h 35m	1:40 PM	Brussels Airport	Brussels Airport	7:15 AM	Prague	ÚAN Florenc	Economy	$108	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/30/2026 1:40:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 8/31/2026 7:15:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 17h 35m
FlixBus	17h 5m	7:35 PM	Brussels Airport	Brussels Airport	12:40 PM	Prague	ÚAN Florenc	Economy	$121	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/30/2026 7:35:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 8/31/2026 12:40:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 17h 5m
FlixBus	23h 40m	1:40 PM	Brussels Airport	Brussels Airport	1:20 PM	Prague	Černý Most	Economy	$122	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/30/2026 1:40:00 PM to Černý Most, Prague (Czech Republic) arriving at 8/31/2026 1:20:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 23h 40m
FlixBus	20h 15m	4:15 AM	Brussels Airport	Brussels Airport	12:30 AM	Prague	Na Knížecí Station	Economy	$123	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/30/2026 4:15:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 8/31/2026 12:30:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 20h 15m
FlixBus	20h 30m	4:15 AM	Brussels Airport	Brussels Airport	12:45 AM	Prague	Wilsonova Bus Station	Economy	$123	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/30/2026 4:15:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 8/31/2026 12:45:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 20h 30m

Did you know that if you travel from Brussels Airport to Prague via Brussels, you can save more than $31? You will find the corresponding connections below.
- FlixBus
  
  Save more than 29%
  
  14h 5m
  
  Brussels Airport
  
  7 mi
  
  10:25 AM
  
  Brussels
  North Station
  
  12:30 AM
  
  Prague
  Na Knížecí Station
  
  0 mi
  
  Economy
  
  $77
  
  A Bus from FlixBus goes from North Station, Brussels (Belgium) at 8/30/2026 10:25:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 8/31/2026 12:30:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 14h 5m
Did you know that if you travel from Brussels Airport to Prague via Maastricht, you can save more than $55? You can find the corresponding connections below.
- FlixBus
  
  23h 45m
  
  0
  
  12:45 AM
  
  Brussels Airport
  Brussels Airport
  
  4:55 AM
  
  Maastricht
  Meerssenerweg
  
  0
  
  Economy
  
  $13
  
  A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 9/1/2026 12:45:00 AM to Meerssenerweg, Maastricht (Netherlands) arriving at 9/1/2026 4:55:00 AM. 50 Economy ticket for $13 per person are available. Travel duration is 4h 10m
- FlixBus
  
  13h 20m
  
  0
  
  11:10 AM
  
  Maastricht
  Meerssenerweg
  
  12:30 AM
  
  Prague
  Na Knížecí Station
  
  0
  
  Economy
  
  $40
  
  A Bus from FlixBus goes from Meerssenerweg, Maastricht (Netherlands) at 9/1/2026 11:10:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 9/2/2026 12:30:00 AM. 50 Economy ticket for $40 per person are available. Travel duration is 13h 20m
Travel time is 6h 40m longer, but you will save $55

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	22h 45m	6:45 PM	Brussels Airport	Brussels Airport	5:30 PM	Prague	Wilsonova Bus Station	Economy	$75	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/31/2026 6:45:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/1/2026 5:30:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 22h 45m
FlixBus	22h 0m	7:35 PM	Brussels Airport	Brussels Airport	5:35 PM	Prague	Hradčanská	Economy	$75	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/31/2026 7:35:00 PM to Hradčanská, Prague (Czech Republic) arriving at 9/1/2026 5:35:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 22h 0m
FlixBus	17h 35m	1:40 PM	Brussels Airport	Brussels Airport	7:15 AM	Prague	ÚAN Florenc	Economy	$75	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/31/2026 1:40:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 9/1/2026 7:15:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 17h 35m
FlixBus	21h 10m	1:50 PM	Brussels Airport	Brussels Airport	11:00 AM	Prague	ÚAN Florenc	Economy	$75	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/31/2026 1:50:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 9/1/2026 11:00:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 21h 10m
FlixBus	17h 35m	7:35 PM	Brussels Airport	Brussels Airport	1:10 PM	Prague	ÚAN Florenc	Economy	$75	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 8/31/2026 7:35:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 9/1/2026 1:10:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 17h 35m

Did you know that if you travel from Brussels Airport to Prague via Brussels, you can save more than $14? You will find the corresponding connections below.
- FlixBus
  
  Save more than 19%
  
  14h 5m
  
  Brussels Airport
  
  7 mi
  
  10:25 AM
  
  Brussels
  North Station
  
  12:30 AM
  
  Prague
  Na Knížecí Station
  
  0 mi
  
  Economy
  
  $61
  
  A Bus from FlixBus goes from North Station, Brussels (Belgium) at 8/31/2026 10:25:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 9/1/2026 12:30:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 14h 5m
Did you know that if you travel from Brussels Airport to Prague via Maastricht, you can save more than $22? You can find the corresponding connections below.
- FlixBus
  
  23h 45m
  
  0
  
  12:45 AM
  
  Brussels Airport
  Brussels Airport
  
  4:55 AM
  
  Maastricht
  Meerssenerweg
  
  0
  
  Economy
  
  $13
  
  A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 9/1/2026 12:45:00 AM to Meerssenerweg, Maastricht (Netherlands) arriving at 9/1/2026 4:55:00 AM. 50 Economy ticket for $13 per person are available. Travel duration is 4h 10m
- FlixBus
  
  13h 20m
  
  0
  
  11:10 AM
  
  Maastricht
  Meerssenerweg
  
  12:30 AM
  
  Prague
  Na Knížecí Station
  
  0
  
  Economy
  
  $40
  
  A Bus from FlixBus goes from Meerssenerweg, Maastricht (Netherlands) at 9/1/2026 11:10:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 9/2/2026 12:30:00 AM. 50 Economy ticket for $40 per person are available. Travel duration is 13h 20m
Travel time is 6h 10m longer, but you will save $22

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	20h 15m	4:15 AM	Brussels Airport	Brussels Airport	12:30 AM	Prague	Na Knížecí Station	Economy	$50	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 9/1/2026 4:15:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 9/2/2026 12:30:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 20h 15m
FlixBus	20h 30m	4:15 AM	Brussels Airport	Brussels Airport	12:45 AM	Prague	Wilsonova Bus Station	Economy	$50	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 9/1/2026 4:15:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/2/2026 12:45:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 20h 30m
FlixBus	21h 25m	4:15 AM	Brussels Airport	Brussels Airport	1:40 AM	Prague	Wilsonova Bus Station	Economy	$50	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 9/1/2026 4:15:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/2/2026 1:40:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 21h 25m
FlixBus	20h 25m	12:45 AM	Brussels Airport	Brussels Airport	9:10 PM	Prague	Na Knížecí Station	Economy	$52	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 9/1/2026 12:45:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 9/1/2026 9:10:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 20h 25m
FlixBus	22h 45m	6:45 PM	Brussels Airport	Brussels Airport	5:30 PM	Prague	Wilsonova Bus Station	Economy	$52	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 9/1/2026 6:45:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/2/2026 5:30:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 22h 45m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	20h 25m	12:45 AM	Brussels Airport	Brussels Airport	9:10 PM	Prague	Na Knížecí Station	Economy	$49	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 9/2/2026 12:45:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 9/2/2026 9:10:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 20h 25m
FlixBus	22h 50m	11:15 AM	Brussels Airport	Brussels Airport	10:05 AM	Prague	Na Knížecí Station	Economy	$49	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 9/2/2026 11:15:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 9/3/2026 10:05:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 22h 50m
FlixBus	20h 15m	4:15 AM	Brussels Airport	Brussels Airport	12:30 AM	Prague	Na Knížecí Station	Economy	$50	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 9/2/2026 4:15:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 9/3/2026 12:30:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 20h 15m
FlixBus	20h 30m	4:15 AM	Brussels Airport	Brussels Airport	12:45 AM	Prague	Wilsonova Bus Station	Economy	$50	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 9/2/2026 4:15:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/3/2026 12:45:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 20h 30m
FlixBus	21h 25m	4:15 AM	Brussels Airport	Brussels Airport	1:40 AM	Prague	Wilsonova Bus Station	Economy	$50	A Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 9/2/2026 4:15:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/3/2026 1:40:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 21h 25m

Best Price Offer: The price for the cheapest bus from Brussels Airport to Prague is $29 on 9/15/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Brussels Airport and Prague

See here how frequent the connections between Brussels Airport and Prague are, during different times and days of the week.

Sunday is the busiest day, with more than 28 daily buses from Brussels Airport to Prague. Wednesday has instead the fewest connections, with only 15 daily coaches between Brussels Airport and Prague.

The busiest time of the day is the Evening, with 73 buses from Brussels Airport to Prague, while Morning sees the fewest connections between Brussels Airport and Prague, with 4 offers.

Facts about the bus from Brussels Airport (BRU) to Prague

Compare all providers like FlixBus that travel 22 times every day by bus from Brussels Airport to Prague in one click! Book your bus ticket from Brussels Airport to Prague starting from $29!

Cheapest Bus	$29
Fastest Bus	16h 35m
Earliest Bus	1:40 PM
Latest Bus	9:30 PM
Daily Bus Routes	22 Ø
Distance	441.0 miles
Bus Companies	FlixBus

Cheapest bus connections from Brussels Airport to Prague

Every day, 22 buses from 1 bus companies leave Brussels Airport for Prague: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 08/27/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 08/23

Monday 08/24

Tuesday 08/25

Wednesday 08/26

Thursday 08/27

$98

Friday 08/28

$108

Saturday 08/29

$107

Sunday 08/30

$108

Monday 08/31

$75

Tuesday 09/01

$50

Wednesday 09/02

$49

Thursday 09/03

$48

Friday 09/04

$69

Saturday 09/05

$56

Sunday 09/06

$73

Monday 09/07

$43

Tuesday 09/08

$33

Wednesday 09/09

$33

Thursday 09/10

$40

Friday 09/11

$50

Saturday 09/12

$47

Sunday 09/13

$52

Monday 09/14

$34

Tuesday 09/15

$29

Wednesday 09/16

$29

Thursday 09/17

$33

Friday 09/18

$41

Saturday 09/19

The cheapest time to travel from Brussels Airport to Prague

See here on which day and which time of the day you can find the cheapest bus ticket from Brussels Airport to Prague, for the next 30 days.

With a price starting from $23, Tuesday is the cheapest day for a bus from Brussels Airport to Prague. Sunday instead is the most expensive day with prices starting from $43.

Night is the cheapest day time for bus tickets from Brussels Airport to Prague, with $23. Afternoon is the most expensive time of the day with prices starting from $54.

How to save money travelling from Brussels Airport to Prague

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Brussels Airport to Prague in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Brussels Airport to Prague, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Brussels Airport to Prague are also emptier.

Beloved bus companies from Brussels Airport to Prague

These are the most booked bus companies between Brussels Airport to Prague from our users.

FlixBus from Brussels Airport to Prague

Here you will find the key facts about the FlixBus bus route Brussels Airport to Prague:

Cheapest Price	$49
Fastest Bus	16h 35m
Earliest Bus	1:40 PM
Last Bus	9:30 PM
Daily Connections	22 Ø
Found on	8/27/2026

All bus stations and stops in Brussels Airport and Prague

In the map below, you can see where to find all bus stations in Brussels Airport and Prague.

Brussels Airport

Zaventem 8

Na Knížecí Station

Za Ženskými domovy / Ostrovského

ÚAN Florenc

Křižíkova 279

Wilsonova Bus Station

Wilsonova 300/8

Roztyly

Tomíčkova 2234

Černý Most

Bryksova

Service and Comfort on the bus from Brussels Airport to Prague

Want to know which seat classes are available on the buses from Brussels Airport to Prague? Or which bus companies serve the route Brussels Airport to Prague? Below you will find answers to your questions.

FAQs about the Brussels Airport to Prague bus

How much does a Brussels Airport Prague bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $29 and takes 20h 25m to reach Prague. Compare offers to save money!

How much could I save by comparing buses from Brussels Airport to Prague?

This route is offered by 1 companies with a range of ticket prices between $29 and $180. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Prague.

On average, how many connections are available from Brussels Airport to Prague each day?

Every day, the Brussels Airport to Prague bus route is served by approximately 22 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Brussels Airport to Prague take?

The fastest shuttle from Brussels Airport to Prague is offered by FlixBus and takes 16h 35m. Bus tickets for this connection cost $115. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first shuttle from Brussels Airport to Prague?

The earliest bus arriving in Prague from Brussels Airport starts at 1:40 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last shuttle from Brussels Airport to Prague?

The latest bus trip departing from Brussels Airport for Prague starts at 9:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Brussels Airport Prague route?

When traveling by shuttle from Brussels Airport to Prague, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Brussels Airport and Prague?

You can check all the direct connections between Brussels Airport and Prague by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Brussels Airport to Prague bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Brussels Airport Prague bus route free of charge. Simply use our search to find a shuttle that is best suited to your needs for your planned travel date.

What equipment is available for the Brussels Airport Prague bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the shuttle from Brussels Airport to Prague on your planned travel date.

How does CheckMyBus find the best bus deals from Brussels Airport to Prague?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 22 daily trips between Brussels Airport and Prague. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Brussels Airport to Prague?

Prices and availability for 22 trips between Brussels Airport and Prague change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Brussels Airport to Prague

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Brussels Airport and to Prague

Here’s an overview of the most popular bus routes to Brussels Airport and to Prague. Simply click on the connection of your choice, and you will find all the details about your bus route!